期刊
CHILDREN-BASEL
卷 10, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/children10050834
关键词
COVID-19; congenital hearing loss; pregnancy
类别
This systematic review aims to assess the possible link between maternal COVID-19 infection and congenital hearing loss. After analyzing 924 candidate papers, only 9 studies were selected for further analysis. The review identified 1687 children born from mothers infected with COVID-19, with a confirmed hearing loss rate of 0.7% (12/1688). However, the selected studies lack information on the nature of hearing loss (sensorineural vs. conductive), and the follow-up periods varied across the studies. Therefore, the correlation between congenital hearing loss and SARS-CoV-2 infection cannot be definitively established, and further studies are needed for additional evidence.
Background and aim: Several viruses have previously been reported to be responsible for congenital hearing loss; therefore, since the beginning of the SARS-CoV-2 infection pandemic, various reports have investigated a possible link. The aim of this review is to assess the possible link between maternal COVID-19 infection and congenital hearing loss. Methods: This systematic review was performed using PRISMA criteria, searching Medline and Embase databases from March 2020 to February 2023. A total of 924 candidate papers were identified; however, considering the specific selection criteria, only nine were selected for additional analysis. Results: The overall number of children born from mothers infected with COVID-19 during pregnancy identified through this review was 1687. The confirmed cases of hearing loss were 0.7% (12/1688); a description of its nature (sensorineural vs. conductive) is missing in the selected studies, and the follow-up period is variable across the analyzed papers. Surprisingly, a large proportion of false positives were recorded at the first stage of screening, which resulted normal at the re-test. Conclusions: Currently, a correlation between congenital hearing loss and SARS-CoV-2 infection cannot be definitively established. Further studies are desirable to provide additional evidence on this topic.
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