相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Synergistic therapeutic effects of intracerebral transplantation of human modified bone marrow-derived stromal cells (SB623) and voluntary exercise with running wheel in a rat model of ischemic stroke
Satoru Yabuno et al.
STEM CELL RESEARCH & THERAPY (2023)
Cellular and Molecular Regulation of Exercise-A Neuronal Perspective
Ishitha Reddy et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2023)
P75 neurotrophin receptor controls subventricular zone neural stem cell migration after stroke
Sachin S. Deshpande et al.
CELL AND TISSUE RESEARCH (2022)
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology
Sen Liu et al.
JOURNAL OF NEUROINFLAMMATION (2022)
New insights into the role of fibroblast growth factors in Alzheimer's disease
Ramy Alam et al.
MOLECULAR BIOLOGY REPORTS (2022)
Mitochondriomics reveals the underlying neuroprotective mechanism of TrkB receptor agonist R13 in the 5xFAD mice
Ting Li et al.
NEUROPHARMACOLOGY (2022)
Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model
Wan-yi Li et al.
MOLECULAR NEUROBIOLOGY (2022)
Neurotrophin-targeted therapeutics: A gateway to cognition and more?
Gunnar Nordvall et al.
DRUG DISCOVERY TODAY (2022)
A Review of Molecular Interplay between Neurotrophins and miRNAs in Neuropsychological Disorders
Sara Abdolahi et al.
MOLECULAR NEUROBIOLOGY (2022)
Neurogenic effects of rotarod walking exercise in subventricular zone, subgranular zone, and substantia nigra in MPTP-induced Parkinson's disease mice
Yea-Hyun Leem et al.
SCIENTIFIC REPORTS (2022)
Environmental Enrichment Reverses Maternal Sleep Deprivation-Induced Anxiety-Like Behavior and Cognitive Impairment in CD-1 Mice
Yue-Ming Zhang et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2022)
Neurotrophin Crosstalk in the Etiology and Treatment of Neuropsychiatric and Neurodegenerative Disease
Rajeev Joshi et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2022)
Physical exercise ameliorates memory impairment in offspring of old mice
Tae-Woon Kim et al.
JOURNAL OF EXERCISE REHABILITATION (2022)
Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity
Ya-Jen Chiu et al.
Aging-US (2022)
Resistance training and Urtica dioica increase neurotrophin levels and improve cognitive function by increasing age in the hippocampus of rats
Masoud Rahmati et al.
BIOMEDICINE & PHARMACOTHERAPY (2022)
Temporal endurance of exercise-induced benefits on hippocampus-dependent memory and synaptic plasticity in female mice
T.N. Dong et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2022)
Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions
Sonalika Bhalla et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2022)
Yuk-Gunja-Tang attenuates neuronal death and memory impairment via ERK/CREB/BDNF signaling in the hippocampi of experimental Alzheimer's disease model
Malk Eun Pak et al.
FRONTIERS IN PHARMACOLOGY (2022)
Review on Alzheimer's disease: Inhibition of amyloid beta and tau tangle formation
Hossein Ashrafian et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)
Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system
Vandreza Cardoso Bortolotto et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2021)
Tadalafil and bergapten mitigate streptozotocin-induced sporadic Alzheimer's disease in mice via modulating neuroinflammation, PI3K/Akt, Wnt/β-catenin, AMPK/mTOR signaling pathways
Mohamed A. Salem et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2021)
Brain-Derived Neurotrophic Factor Signaling in the Pathophysiology of Alzheimer's Disease: Beneficial Effects of Flavonoids for Neuroprotection
Tadahiro Numakawa et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers
Sumonto Mitra et al.
FRONTIERS IN AGING NEUROSCIENCE (2021)
Serum pro-BDNF levels correlate with phospho-tau staining in Alzheimer's disease
Krishna L. Bharani et al.
NEUROBIOLOGY OF AGING (2020)
GDNF, A Neuron-Derived Factor Upregulated in Glial Cells during Disease
Marcelo Duarte Azevedo et al.
JOURNAL OF CLINICAL MEDICINE (2020)
Low and High Molecular Weight FGF-2 Have Differential Effects on Astrocyte Proliferation, but Are Both Protective Against Aβ-Induced Cytotoxicity
Xi Chen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)
Pathways Connecting Late-Life Depression and Dementia
Christoph Linnemann et al.
FRONTIERS IN PHARMACOLOGY (2020)
RET-independent signaling by GDNF ligands and GFRα receptors
Carlos F. Ibanez et al.
CELL AND TISSUE RESEARCH (2020)
Intracellular RET signaling pathways activated by GDNF
Kumi Kawai et al.
CELL AND TISSUE RESEARCH (2020)
IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model
Mona Sohrabi et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2020)
The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease
Meysam Amidfar et al.
LIFE SCIENCES (2020)
Comprehensive Review on Alzheimer's Disease: Causes and Treatment
Zeinab Breijyeh et al.
MOLECULES (2020)
FGF/FGFR signaling in health and disease
Yangli Xie et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
GDNF and alcohol use disorder
Segev Barak et al.
ADDICTION BIOLOGY (2019)
Heparan sulfate proteoglycan - A common receptor for diverse cytokines
Meng Xie et al.
CELLULAR SIGNALLING (2019)
The Role of PI3K/Akt and ERK in Neurodegenerative Disorders
Sachchida Nand Rai et al.
NEUROTOXICITY RESEARCH (2019)
Kaempferide prevents cognitive decline via attenuation of oxidative stress and enhancement of brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response element-binding signaling pathway
Tingxu Yan et al.
PHYTOTHERAPY RESEARCH (2019)
Unifying Hypothesis of Dopamine Neuron Loss in Neurodegenerative Diseases: Focusing on Alzheimer's Disease
Paraskevi Krashia et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer's Disease
Zhi-Hao Wang et al.
CELL REPORTS (2019)
Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders
Sweta Bawari et al.
PHARMACOLOGICAL RESEARCH (2019)
GDNF and GFRα1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons
Antonela Bonafina et al.
CELL REPORTS (2019)
GFRA1: A Novel Molecular Target for the Prevention of Osteosarcoma Chemoresistance
Mihwa Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease
Chun Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
p75 Neurotrophin Receptor: A Double-Edged Sword in Pathology and Regeneration of the Central Nervous System
Kathrin Becker et al.
VETERINARY PATHOLOGY (2018)
Genetic Dissection of Presynaptic and Postsynaptic BDNF-TrkB Signaling in Synaptic Efficacy of CA3-CA1 Synapses
Pei-Yi Lin et al.
CELL REPORTS (2018)
Type 2 Diabetes Mellitus and Alzheimer's Disease: Role of Insulin Signalling and Therapeutic Implications
Andrea Tumminia et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Icariside II Ameliorates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Inhibiting the Amyloidogenic Pathway: Involvement of BDNF/TrkB/CREB Signaling and Up-Regulation of PPARα and PPARγ in Rats
Caixia Yin et al.
FRONTIERS IN PHARMACOLOGY (2018)
Antidepressant-Like Effects of Low- and High-Molecular Weight FGF-2 on Chronic Unpredictable Mild Stress Mice
Lin Wang et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease
M. Florencia Iulita et al.
NEUROBIOLOGY OF DISEASE (2017)
PI3K/Akt and ERK/MAPK Signaling Promote Different Aspects of Neuron Survival and Axonal Regrowth Following Rat Facial Nerve Axotomy
Haitao Huang et al.
NEUROCHEMICAL RESEARCH (2017)
IGF-1 protects against Aβ25-35-induced neuronal cell death via inhibition of PUMA expression and Bax activation
Xunyao Hou et al.
NEUROSCIENCE LETTERS (2017)
PGC-1 α or FNDC5 Is Involved in Modulating the Effects of Aβ1-42 Oligomers on Suppressing the Expression of BDNF, a Beneficial Factor for Inhibiting Neuronal Apoptosis, Aβ Deposition and Cognitive Decline of APP/PS1 Tg Mice
De-Yu Xia et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease
Elyse Rosa et al.
NEUROBIOLOGY OF AGING (2016)
Neuroprotective effects of LMW and HMW FGF2 against amyloid beta toxicity in primary cultured hippocampal neurons
Yong Cheng et al.
NEUROSCIENCE LETTERS (2016)
Immunomodulator CD200 Promotes Neurotrophic Activity by Interacting with and Activating the Fibroblast Growth Factor Receptor
Stanislava Pankratova et al.
MOLECULAR NEUROBIOLOGY (2016)
Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance
Geraldine Gontier et al.
JOURNAL OF NEUROSCIENCE (2015)
ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation
Abhik Sen et al.
JOURNAL OF NEUROSCIENCE (2015)
Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice
Ariana Q. Farrand et al.
NEUROBIOLOGY OF AGING (2015)
Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice
Loukia Katsouri et al.
NEUROBIOLOGY OF AGING (2015)
CREB expression mediates amyloid β-induced basal BDNF downregulation
Elyse Rosa et al.
NEUROBIOLOGY OF AGING (2015)
Insulin resistance in brain alters dopamine turnover and causes behavioral disorders
Andre Kleinridders et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease
Josiane Budni et al.
AGING AND DISEASE (2015)
Decreased Neurotrophic Support is Associated with Cognitive Decline in Non-Demented Subjects
Orestes Vicente Forlenza et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
The ins and outs of fibroblast growth factor receptor signalling
Stacey J. Coleman et al.
CLINICAL SCIENCE (2014)
Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells
Susana Revilla et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Insulin Action in Brain Regulates Systemic Metabolism and Brain Function
Andre Kleinridders et al.
DIABETES (2014)
Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease
Chi Zhang et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain
Susana Revilla et al.
NEUROPHARMACOLOGY (2014)
Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis
Marianna Sadagurski et al.
MOLECULAR METABOLISM (2014)
Fibroblast growth factor (FGF) signaling in development and skeletal diseases
Chad M. Teven et al.
GENES & DISEASES (2014)
Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease
Oliver Stoehr et al.
AGE (2013)
TrkB Receptor Signalling: Implications in Neurodegenerative, Psychiatric and Proliferative Disorders
Vivek K. Gupta et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Modeling Alzheimer's disease in transgenic rats
Sonia Do Carmo et al.
MOLECULAR NEURODEGENERATION (2013)
Neurotrophin regulation of neural circuit development and function
Hyungju Park et al.
NATURE REVIEWS NEUROSCIENCE (2013)
Growth Hormone-Releasing Hormone Effects on Brain γ-Aminobutyric Acid Levels in Mild Cognitive Impairment and Healthy Aging
Seth D. Friedman et al.
JAMA NEUROLOGY (2013)
Genetic deletion of trkB.T1 increases neuromuscular function
Susan G. Dorsey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
Effects of Growth Hormone-Releasing Hormone on Cognitive Function in Adults With Mild Cognitive Impairment and Healthy Older Adults Results of a Controlled Trial
Laura D. Baker et al.
ARCHIVES OF NEUROLOGY (2012)
Effect of bFGF on neuronal damage induced by sequential treatment of amyloid β and excitatory amino acid in vitro and in vivo
Takafumi Noshita et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of β-amyloid and ibotenic acid into the bilateral hippocampus
Chengcheng Feng et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)
Influence of Lithium Treatment on GDNF Serum and CSF Concentrations in Patients with Early Alzheimer's Disease
Guido Straten et al.
CURRENT ALZHEIMER RESEARCH (2011)
Glucocorticoid suppresses BDNF-stimulated MAPK/ERK pathway via inhibiting interaction of Shp2 with TrkB
Emi Kumamaru et al.
FEBS LETTERS (2011)
Identification of Novel GDNF Isoforms and cis-Antisense GDNFOS Gene and Their Regulation in Human Middle Temporal Gyrus of Alzheimer Disease
Mikko Airavaara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Alcohol Reward, Dopamine Depletion, and GDNF
Charles L. Pickens et al.
JOURNAL OF NEUROSCIENCE (2011)
Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease
Josef Marksteiner et al.
NEUROBIOLOGY OF AGING (2011)
FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders
Tomomi Kiyota et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A Novel Transgenic Rat Model with a Full Alzheimer's-Like Amyloid Pathology Displays Pre-Plaque Intracellular Amyloid-beta-Associated Cognitive Impairment
Wanda Carolina Leon et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis
D. Taliaz et al.
MOLECULAR PSYCHIATRY (2010)
Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons
Yuanyuan Ji et al.
NATURE NEUROSCIENCE (2010)
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
Sung-Wuk Jang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice
Richard Killick et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice
Ehud Cohen et al.
CELL (2009)
Neuronal IGF-1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer's disease
Susanna Freude et al.
FASEB JOURNAL (2009)
Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-γ signaling for glutamate release via a glutamate transporter
Tadahiro Numakawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Insulin-like signaling, nutrient homeostasis, and life span
Akiko Taguchi et al.
ANNUAL REVIEW OF PHYSIOLOGY (2008)
Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease
Leah R. Hanson et al.
BMC NEUROSCIENCE (2008)
Glucocorticoid prevents brain-derived neurotrophic factor-mediated maturation of synaptic function in developing hippocampal neurons through reduction in the activity of mitogen-activated protein kinase
Emi Kumamaru et al.
MOLECULAR ENDOCRINOLOGY (2008)
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment
Yun Li et al.
NEURON (2008)
Beta-amyloid toxicity in embryonic rat astrocytes
Poincyane Assis-Nascimento et al.
NEUROCHEMICAL RESEARCH (2007)
BDNF regulates the expression and traffic of NMDA receptors in cultured hippocampal neurons
Margarida V. Caldeira et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Brain-derived neurotrophic factor regulates the expression and synaptic delivery of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons
Margarida V. Caldeira et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Neuratrophin-regulated signalling pathways
Louis F. Reichardt
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2006)
Interaction of survival and death signaling in basal forebrain neurons: Roles of neurotrophins and proneurotrophins
Marta Volosin et al.
JOURNAL OF NEUROSCIENCE (2006)
Brain-derived neurotrophic factor-induced potentiation of glutamate and GABA release: Different dependency on signaling pathways and neuronal activity
T Matsumoto et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2006)
The insulin-like growth factor system and its pleiotropic functions in brain
VC Russo et al.
ENDOCRINE REVIEWS (2005)
TrkB has a cell-autonomous role in the establishment of hippocampal schaffer collateral synapses
BW Luikart et al.
JOURNAL OF NEUROSCIENCE (2005)
Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats
H Scharfman et al.
EXPERIMENTAL NEUROLOGY (2005)
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons
M Alonso et al.
LEARNING & MEMORY (2004)
Sortilin is essential for proNGF-induced neuronal cell death
A Nykjaer et al.
NATURE (2004)
Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
XL He et al.
SCIENCE (2004)
Ability of GDNF to diminish free radical production leads to protection against kainate-induced excitotoxicity in hippocampus
H Cheng et al.
HIPPOCAMPUS (2004)
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
M Schubert et al.
JOURNAL OF NEUROSCIENCE (2003)
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
M Holzenberger et al.
NATURE (2003)
GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial bax translocation
O Ghribi et al.
NEUROBIOLOGY OF DISEASE (2001)
Role of brain insulin receptor in control of body weight and reproduction
JC Brüning et al.
SCIENCE (2000)
NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR
J Mukai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Growth factor effects on survival and development of calbindin immunopositive cultured septal neurons
A Silva et al.
BRAIN RESEARCH BULLETIN (2000)
Neurotrophic factors protect cortical synaptic terminals against amyloid- and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function
ZH Guo et al.
CEREBRAL CORTEX (2000)