相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Neuronal subset-specific phosphatase and tensin homolog knockout mice exhibit age and brain region-associated alterations in microglia/macrophage activation
David A. Narvaiz et al.
NEUROREPORT (2022)
mTOR-driven neural circuit changes initiate an epileptogenic cascade
Candi L. LaSarge et al.
PROGRESS IN NEUROBIOLOGY (2021)
Microvascular changes associated with epilepsy: A narrative review
Rick H. G. J. van Lanen et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2021)
The glucocorticoid receptor specific modulator CORT108297 reduces brain pathology following status epilepticus
Aynara C. Wulsin et al.
EXPERIMENTAL NEUROLOGY (2021)
Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro
D. W. M. Broekaart et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2020)
Tuberous Sclerosis (tsc2+/-) Model Eker Rats Reveals Extensive Neuronal Loss with Microglial Invasion and Vascular Remodeling Related to Brain Neoplasia
Viera Kutna et al.
NEUROTHERAPEUTICS (2020)
Imaging of PTEN-related abnormalities in the central nervous system
Radhika Dhamija et al.
CLINICAL IMAGING (2020)
First comprehensive TSC1/TSC2 mutational analysis in Mexican patients with Tuberous Sclerosis Complex reveals numerous novel pathogenic variants
Miriam E. Reyna-Fabian et al.
SCIENTIFIC REPORTS (2020)
PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
Angela R. White et al.
NEUROBIOLOGY OF DISEASE (2020)
mTORopathies: A Road Well-Traveled
Peter B. Crino
EPILEPSY CURRENTS (2020)
Breakdown of blood brain barrier as a mechanism of post-traumatic epilepsy
Aaron Dadas et al.
NEUROBIOLOGY OF DISEASE (2019)
Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth
Salwa R. Arafa et al.
EXPERIMENTAL NEUROLOGY (2019)
Hypervascularization in mTOR-dependent focal and global cortical malformations displays differential rapamycin sensitivity
Longbo Zhang et al.
EPILEPSIA (2019)
Intracranial aneurysms in patients with tuberous sclerosis complex: a systematic review
Mehdi Chihi et al.
JOURNAL OF NEUROSURGERY-PEDIATRICS (2019)
The Roof is Leaking and a Storm is Raging: Repairing the Blood-Brain Barrier in the Fight Against Epilepsy
J. A. Gorter et al.
EPILEPSY CURRENTS (2019)
The Blood-Brain Barrier Breakdown During Acute Phase of the Pilocarpine Model of Epilepsy Is Dynamic and Time-Dependent
Natalia Ferreira Mendes et al.
FRONTIERS IN NEUROLOGY (2019)
Vascular malformations syndromes: an update
Antonio Martinez-Lopez et al.
CURRENT OPINION IN PEDIATRICS (2019)
Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
Candi L. LaSarge et al.
EXPERIMENTAL NEUROLOGY (2019)
Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency
Chien-Ju Chen et al.
NATURE MEDICINE (2019)
Vascular hyperpermeability as a hallmark of phacomatoses: is the etiology angiogenesis comparable with mechanisms seen in inflammatory pathways? Part I: historical observations and clinical perspectives on the etiology of increased CSF protein levels, CSF clotting, and communicating hydrocephalus: a comprehensive review
Yosef Laviv et al.
NEUROSURGICAL REVIEW (2018)
PTEN inhibition enhances angiogenesis in an in vitro model of ischemic injury by promoting Akt phosphorylation and subsequent hypoxia inducible factor-1α upregulation
Lixia Xue et al.
METABOLIC BRAIN DISEASE (2018)
Review: Mechanistic target of rapamycin (mTOR) pathway, focal cortical dysplasia and epilepsy
E. Marsan et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2018)
Blood-Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit
Marion Bankstahl et al.
ENEURO (2018)
PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network
Caitlynn M. Barrows et al.
JOURNAL OF NEUROSCIENCE (2017)
PTEN deletion increases hippocampal granule cell excitability in male and female mice
Victor R. Santos et al.
NEUROBIOLOGY OF DISEASE (2017)
The genomic landscape of tuberous sclerosis complex
Katie R. Martin et al.
NATURE COMMUNICATIONS (2017)
Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats I: Magnetic resonance imaging
Erwin A. van Vliet et al.
EPILEPSIA (2016)
Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms
Erwin A. van Vliet et al.
EPILEPSIA (2016)
Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain
Michael S. Hester et al.
EXPERIMENTAL NEUROLOGY (2016)
Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells
Candi L. LaSarge et al.
NEUROBIOLOGY OF DISEASE (2016)
Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism
Ghayda M. Mirzaa et al.
JAMA NEUROLOGY (2016)
Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex
Angelika Muehlebner et al.
PLOS ONE (2016)
PTEN deletion from adult-generated dentate granule cells disrupts granule cell mossy fiber axon structure
Candi L. LaSarge et al.
NEUROBIOLOGY OF DISEASE (2015)
Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction
Ji-Yoen Kim et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2014)
Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex
David M. Feliciano et al.
HUMAN MOLECULAR GENETICS (2013)
Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling: Correlation With Histopathological Vascular Density
Pia Wintermark et al.
JOURNAL OF CHILD NEUROLOGY (2013)
T11TS impedes glioma angiogenesis by inhibiting VEGF signaling and pro-survival PI3K/Akt/eNOS pathway with concomitant upregulation of PTEN in brain endothelial cells
Debanjan Bhattacharya et al.
JOURNAL OF NEURO-ONCOLOGY (2013)
Long-lasting pro-ictogenic effects induced in vivo by rat brain exposure to serum albumin in the absence of concomitant pathology
Federica Frigerio et al.
EPILEPSIA (2012)
Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation
Erwin A. van Vliet et al.
EPILEPSIA (2012)
Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis
John McMahon et al.
JOURNAL OF NEUROSCIENCE (2012)
Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration
Margaret Sperow et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Excessive Activation of mTOR in Postnatally Generated Granule Cells Is Sufficient to Cause Epilepsy
Raymund Y. K. Pun et al.
NEURON (2012)
Enhanced Epidermal Growth Factor, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor Expression in Tuberous Sclerosis Complex
Whitney E. Parker et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
PI3K/AKT/mTOR pathway in angiogenesis
Jayashree Karar et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2011)
PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and -independent mechanisms in HepG2 cells
Tao Tian et al.
CARCINOGENESIS (2010)
VASCULAR CHANGES IN EPILEPSY: FUNCTIONAL CONSEQUENCES AND ASSOCIATION WITH NETWORK PLASTICITY IN PILOCARPINE-INDUCED EXPERIMENTAL EPILEPSY
X. E. Ndode-Ekane et al.
NEUROSCIENCE (2010)
Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
Carol Kilkenny et al.
PLOS BIOLOGY (2010)
The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy
Ling-Hui Zeng et al.
JOURNAL OF NEUROSCIENCE (2009)
Age-dependent vascular changes induced by status epilepticus in rat forebrain: Implications for epileptogenesis
Jessica Marcon et al.
NEUROBIOLOGY OF DISEASE (2009)
Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif
Stephen C. Land et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Somatic induction of Pten loss in a preclinical astrocytoma model reveals major roles in disease progression and avenues for target discovery and validation
A Xiao et al.
CANCER RESEARCH (2005)
Clinical and experimental studies of epilepsy associated with focal cortical dysplasia
K Hashizume et al.
PSYCHIATRY AND CLINICAL NEUROSCIENCES (2004)
mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
CH Kwon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
TSC2 regulates VEGF through mTOR-dependent and -independent pathways
JB Brugarolas et al.
CANCER CELL (2003)
Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis
C Gomez-Manzano et al.
ANNALS OF NEUROLOGY (2003)
PTEN controls tumor-induced angiogenesis
SH Wen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
分享论文
