Muscle Activity during Passive and Active Movements in Preterm and Full-Term Infants

Manifestation of muscle reactions at an early developmental stage may reflect the processes underlying the generation of appropriate muscle tone, which is also an integral part of all movements. In preterm infants, some aspects of muscular development may occur differently than in infants born at term. Here we evaluated early manifestations of muscle tone by measuring muscle responses to passive stretching (StR) and shortening (ShR) in both upper and lower limbs in preterm infants (at the corrected age from 0 weeks to 12 months), and compared them to those reported in our previous study on full-term infants. In a subgroup of participants, we also assessed spontaneous muscle activity during episodes of relatively large limb movements. The results showed very frequent StR and ShR, and also responses in muscles not being primarily stretched/shortened, in both preterm and full-term infants. A reduction of sensorimotor responses to muscle lengthening and shortening with age suggests a reduction in excitability and/or the acquisition of functionally appropriate muscle tone during the first year of life. The alterations of responses during passive and active movements in preterm infants were primarily seen in the early months, perhaps reflecting temporal changes in the excitability of the sensorimotor networks.

Automated summary

This study investigates the early manifestations of muscle tone in preterm infants and compared them to full-term infants. The results suggest a reduction in sensorimotor responses to muscle lengthening and shortening, indicating a decrease in excitability and the development of appropriate muscle tone during the first year of life. The alterations in responses observed in preterm infants primarily occur in the early months, possibly reflecting changes in the excitability of the sensorimotor networks.