☆ 4.6 Review

An Insight into Advances in Developing Nanotechnology Based Therapeutics, Drug Delivery, Diagnostics and Vaccines: Multidimensional Applications in Tuberculosis Disease Management

PHARMACEUTICALS (2023)

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Article Immunology

Engineering zinc oxide hybrid selenium nanoparticles for synergetic anti-tuberculosis treatment by combining Mycobacterium tuberculosis killings and host cell immunological inhibition

Wensen Lin et al.

Summary: In this study, the researchers synthesized zinc oxide-selenium nanoparticles (ZnO-Se NPs) that combine the anti-TB activities of zinc oxide and selenium. The results showed that ZnO-Se NPs effectively killed extracellular Mycobacterium tuberculosis (Mtb) and inhibited intracellular Mtb growth. This was achieved by increasing the production of antibacterial substances and promoting host cell immune responses such as apoptosis.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2023)

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Article Chemistry, Multidisciplinary

Nano-Delivery System of Ethanolic Extract of Propolis Targeting Mycobacterium tuberculosis via Aptamer-Modified-Niosomes

Sirikwan Sangboonruang et al.

Summary: This study developed a niosome-based drug delivery platform for ethanolic extract of propolis (EEP) to target Mycobacterium tuberculosis (Mtb). The platform showed antimycobacterial activity and no toxicity on alveolar macrophages.

NANOMATERIALS (2023)

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Review Pharmacology & Pharmacy

Nanosized Drug Delivery Systems to Fight Tuberculosis

Tom Bourguignon et al.

Summary: Tuberculosis (TB) is the second deadliest infectious disease, and current therapies have limitations. Nanosized drug delivery systems (DDSs) have the potential to optimize TB treatment by reducing toxicity and improving efficiency. Numerous publications have shown growing interest in this field. This review explores the challenges and relevant publications related to using drug nanocarriers for TB treatment. The reviewed studies demonstrate that DDSs can optimize antibacterial effects, reduce doses and toxicity, and mitigate the emergence of resistant strains, but there is still a lack of clinical applications and in vivo proof of concept for these nanosized DDSs.

PHARMACEUTICS (2023)

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Article Developmental Biology

Designing of SiO2 mesoporous nanoparticles loaded with mometasone furoate for potential nasal drug delivery: Ex vivo evaluation and determination of pro-inflammatory interferon and interleukin mRNA expression

Yasir Mehmood et al.

Frontiers in Cell and Developmental Biology (2023)

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Review Materials Science, Biomaterials

Treatments of Mycobacterium tuberculosis and Toxoplasma gondii with Selenium Nanoparticles

Ikhazuagbe H. Ifijen et al.

Summary: Toxoplasma gondii and Mycobacterium tuberculosis are harmful pathogens to humans, and their interaction can be fatal to public health. There is a strong correlation between these infections, with one infection affecting the other reciprocally. Novel therapeutics are urgently needed to address these challenges.

BIONANOSCIENCE (2023)

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Review Infectious Diseases

A Current Perspective on the Potential of Nanomedicine for Anti-Tuberculosis Therapy

Khushboo Borah Slater et al.

Summary: Tuberculosis is a deadly infectious disease caused by Mycobacterium tuberculosis, with over a million annual deaths. The emergence of antimicrobial resistance in TB poses a serious problem that requires urgent treatment. Nanomedicine shows promise in delivering drugs effectively using nanoparticles, reducing drug doses and side effects, and improving patient compliance and recovery.

TROPICAL MEDICINE AND INFECTIOUS DISEASE (2023)

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Article Environmental Sciences

Bio-inspired polynorepinephrine based nanocoatings for reduced graphene oxide/gold nanoparticles composite for high-performance biosensing of Mycobacterium tuberculosis

Neha Bisht et al.

Summary: Polydopamine (PDA) has been widely used as a grafting and coating material for electrochemically active nanomaterials, while its sister compound, polynorepinephrine (PNE), with additional -OH groups and better coating uniformity and biocompatibility, has not been studied in biosensors. This study investigated PNE as a coating material for graphene oxide (RGO) and gold nanoparticles (Au) to develop an electrochemical genosensor for MTB detection. The results showed that RGO/PNE/Au exhibited superior biosensing performance compared to RGO/PDA/Au.

ENVIRONMENTAL RESEARCH (2023)

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Review Cell Biology

Nano-biotechnology in tumour and cancerous disease: A perspective review

Ambikesh Soni et al.

Summary: In recent years, the nanobiotechnology approach has been considered by drug manufacturers and researchers to improve the drug delivery system for tumour and cancer diseases. This article reviews current strategies to improve tumour and cancer drug delivery, focusing on biocompatibility, biodistribution, and active targeting. Nanoparticle-based drug delivery provides target-specific delivery and controlled release, offering a better therapeutic window for treatment options by eradicating diseased cells while sparing normal cells. Nanoparticle-based therapy also overcomes the challenges of treating brain tumors by breaching the blood-brain barriers, improving drug delivery to the target.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2023)

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Article Biochemistry & Molecular Biology

Antagonist Impact of Selenium-Based Nanoparticles Against Mycobacterium tuberculosis

Shagufta Parveen et al.

Summary: Tuberculosis (TB) has been identified as a major cause of global deaths from a single-point infectious agent, mainly due to multi-drug resistance. As a result, there is significant research interest in developing alternative treatment methodologies. The application of nanoparticles has been found to have substantial potential as a delivery medium and bactericidal agent. This study evaluated the efficacy of selenium nanoparticles in inhibiting the growth of Mycobacterium tuberculosis, and the results showed that the synthesized selenium nanoparticles disrupted the integrity of the cell envelope and effectively inhibited its growth. This study proposes a novel approach and opens new avenues in nanoparticle-induced cell disruption strategies.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2023)

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Review Chemistry, Physical

Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders

Tanima Bhattacharya et al.

Summary: The strategies for therapeutics development for neurodegenerative disorders are complex and challenging due to the blood-brain barrier. Nanotechnology combined with phytomedicine shows promise in enhancing drug delivery to the brain and reducing adverse effects.

MATERIALS (2022)

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Article Engineering, Chemical

Novel Green Approaches for the Preparation of Gold Nanoparticles and Their Promising Potential in Oncology

Tanima Bhattacharya et al.

Summary: Metallic nanoparticles, particularly gold nanoparticles, show great potential in achieving targeted drug delivery in cancer therapy. They offer advantages over other metal nanoparticles and have recently been explored for novel, greener synthesis strategies.

PROCESSES (2022)

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Review Nanoscience & Nanotechnology

Emerging Trends in the Delivery of Resveratrol by Nanostructures: Applications of Nanotechnology in Life Sciences

Hitesh Chopra et al.

Summary: Resveratrol is a natural polyphenolic compound with anticancer, antioxidant, anti-inflammatory, and cardioprotective effects. However, its low solubility, poor bioavailability, and short half-life hinder its potential. Nanoencapsulation technology is an effective method to improve the antioxidant effect of resveratrol and enhance its therapeutic efficacy.

JOURNAL OF NANOMATERIALS (2022)

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Review Nanoscience & Nanotechnology

Nanomaterials: A Promising Therapeutic Approach for Cardiovascular Diseases

Hitesh Chopra et al.

Summary: Cardiovascular diseases are a leading cause of death worldwide, and traditional treatments lack safety and effectiveness. Therefore, there is an urgent need for innovative nanomaterials for disease diagnosis and treatment. The small size of nanomaterials enables them to reach the heart and arteries more effectively, making them ideal for treating cardiovascular diseases.

JOURNAL OF NANOMATERIALS (2022)

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Article Chemistry, Physical

Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine

Nehal E. Elsadek et al.

Summary: Electrospinning is a customizable drug delivery technique that fabricates drug-loaded nanofibers using various polymers. These nanofibers have applications in cancer therapy, microbial infections, and regenerative medicine. They offer controlled drug release, high loading capability, and cost-effectiveness, making them promising for improving chemotherapy efficiency, antimicrobial drug delivery, wound healing, and tissue regeneration.

MATERIALS (2022)

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Review Biotechnology & Applied Microbiology

A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases

Siqin He et al.

Summary: Pulmonary drug delivery is an important approach for treating infectious lung diseases, with unique advantages. This review article examines literature on pulmonary delivery strategies in the past decade, offering new perspectives for future treatments.

JOURNAL OF NANOBIOTECHNOLOGY (2022)

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Review Biotechnology & Applied Microbiology

Green Metallic Nanoparticles: Biosynthesis to Applications

Hitesh Chopra et al.

Summary: Advancements in nanotechnology have led to the development of new nanomaterials, but they also bring potential health and environmental risks. Researchers are working to optimize eco-friendly procedures for creating metal and metal oxide nanoparticles. Using biomaterials for nanoparticle preparation is a beneficial approach in green nanotechnology. However, there are unresolved issues that require further research and understanding.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)

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Article Nanoscience & Nanotechnology

Fabrication of Silver Nanoparticles from Ziziphus nummularia Fruit Extract: Effect on Hair Growth Rate and Activity against Selected Bacterial and Fungal Strains

Muhammad Saqib Khalil et al.

Summary: Nanoparticles, particularly silver nanoparticles, are widely used in biomedical and biotechnological research due to their unique physical properties and high permeability. In this study, silver nanoparticles were prepared using Ziziphus nummularia fruit extract and silver nitrate solution, and their hair growth and antibacterial and antifungal activities were evaluated. The results showed that Z. nummularia-AgNPs exhibited effective hair growth activity and showed potential for biomedical and pharmaceutical applications.

JOURNAL OF NANOMATERIALS (2022)

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Article Nanoscience & Nanotechnology

Fabrication of Silver Nanoparticles from Ziziphus nummularia Fruit Extract: Effect on Hair Growth Rate and Activity against Selected Bacterial and Fungal Strains

Muhammad Saqib Khalil et al.

Summary: Nanoparticles, especially silver nanoparticles, are widely used in biomedical and biotechnological research due to their unique properties. This study demonstrated the preparation and characterization of silver nanoparticles using Ziziphus nummularia fruit extract, which showed significant effects on hair growth and antibacterial activities. The findings suggest the potential of Z. nummularia-AgNPs in diverse biomedical and pharmaceutical applications.

JOURNAL OF NANOMATERIALS (2022)

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Article Pharmacology & Pharmacy

Supramolecular assembly of rifampicin and PEGylated PAMAM dendrimer as a novel conjugate for tuberculosis

Rami Ahmed et al.

Summary: The study successfully developed PEGylated G4 PAMAM dendrimers as a suitable drug carrier for rifampicin, with negligible cytotoxicity, high loading potential, and prolonged-release behavior. PEGylated dendrimers exhibited a slower release rate compared to the native/unmodified formulation and free drug, with significantly improved toxicity after PEGylation, and negligible toxicity detected for formulations with 100% functionalization.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

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Article Infectious Diseases

Global Tuberculosis Report 2020-Reflections on the Global TB burden, treatment and prevention efforts

Jeremiah Chakaya et al.

Summary: The global TB report for October 2020 highlights slow progress in TB control efforts and the need to ramp up screening and diagnostic test services. Key drivers of TB, including undernutrition, poverty, diabetes, tobacco smoking, and household air pollution, must be addressed to achieve WHO 2035 TB care and prevention targets. Global focus is needed on the development of new vaccines for TB using new technological methods.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Review Biotechnology & Applied Microbiology

Nanotechnology against the novel coronavirus (severe acute respiratory syndrome coronavirus 2): diagnosis, treatment, therapy and future perspectives

Hamid Rashidzadeh et al.

Summary: COVID-19, an emerging infectious disease, has caused significant impact on global health. Nanotechnology offers promising tools for designing effective diagnostic and therapeutic agents against the virus, showing potential in disease management.

NANOMEDICINE (2021)

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Article Biochemistry & Molecular Biology

Safe Polycationic Dendrimers as Potent Oral In Vivo Inhibitors of Mycobacterium tuberculosis: A New Therapy to Take Down Tuberculosis

Serge Mignani et al.

Summary: This study presents a novel class of antimycobacterial agents, polycationic phosphorus dendrimers, which exhibit intrinsic activity against drug-resistant strains of Mycobacterium tuberculosis. These dendrimers show significant efficacy in vivo and outperform ethambutol and rifampicin in treating TB infections.

BIOMACROMOLECULES (2021)

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Article Pharmacology & Pharmacy

Alginate-Capped Silver Nanoparticles as a Potent Anti-mycobacterial Agent Against Mycobacterium tuberculosis

Cheng-Cheung Chen et al.

Summary: Traditional TB treatments face challenges such as poor patient compliance and drug resistance, but the use of alginate-capped silver nanoparticles shows promise as an effective alternative therapy, with demonstrated efficacy against drug-resistant and dormant Mtb strains.

FRONTIERS IN PHARMACOLOGY (2021)

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Review Biochemistry & Molecular Biology

Inorganic Nanoparticles and Composite Films for Antimicrobial Therapies

Vera Alexandra Spirescu et al.

Summary: The development of drug-resistant microorganisms poses a critical challenge to modern medicine and drug discovery, necessitating innovative strategies to combat global health issues. Metal and metal oxide nanoparticles have shown promise as effective nanobiocides and nanocarriers for antimicrobial drugs, offering potential solutions to combat infections.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Cell Biology

Natural Products for the Management of Castration-Resistant Prostate Cancer: Special Focus on Nanoparticles Based Studies

Rajeev K. Singla et al.

Summary: Prostate cancer is the most common cancer among men and its progression to castration-resistant prostate cancer is a major challenge in disease management. Resistance mechanisms include activation of androgen receptors and tumor microenvironment. Natural products show potential against resistance pathways but face limitations in clinical trials due to unfavorable pharmacological properties. Nanoparticle formulations offer promise in overcoming these limitations for effective treatment.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

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Review Biochemistry & Molecular Biology

Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets

Hitesh Chopra et al.

Summary: Curcuma longa, known for its therapeutic benefits worldwide, contains curcumin as its active component, which has been utilized in treatments for various disorders. Researchers have explored different techniques to enhance the therapeutic potential and pharmacological activity of the plant. The focus now is on developing physicochemical and biological studies to improve target specificity.

MOLECULES (2021)

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Review Pharmacology & Pharmacy

The Application of Inorganic Nanoparticles in Molecular Targeted Cancer Therapy: EGFR Targeting

Meng Sun et al.

Summary: Inorganic nanomaterials are increasingly utilized in EGFR-mediated therapy to address limitations and enhance the efficacy of molecular targeted cancer treatment. Their ease of preparation, modification, and biosecurity make them promising candidates for cancer treatment research aimed at improving EGFR-targeted therapy.

FRONTIERS IN PHARMACOLOGY (2021)

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Article Pharmacology & Pharmacy

Nanotechnology-Based Targeted Drug Delivery: An Emerging Tool to Overcome Tuberculosis

Zsuzsa Baranyai et al.

Summary: The emergence and rapid spread of drug resistant strains of tuberculosis pose a serious threat to public health, increasing the demand for more effective therapies. Nanotechnology has emerged as a tool to improve current treatments by using antimicrobial-loaded nanocarriers for targeted drug delivery to Mycobacterium tuberculosis-infected macrophages. This strategy aims to increase local drug concentration and enhance treatment efficacy in order to overcome the challenges in TB treatment.

ADVANCED THERAPEUTICS (2021)

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Article Pharmacology & Pharmacy

Mechanisms of the effectiveness of lipid nanoparticle formulations loaded with anti-tubercular drugs combinations toward overcoming drug bioavailability in tuberculosis

Subham Banerjee et al.

JOURNAL OF DRUG TARGETING (2020)

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Article Chemistry, Inorganic & Nuclear

Commercial Yeast Extracts Mediated Green Synthesis of Silver Chloride Nanoparticles and their Anti-mycobacterial Activity

Anbarasu Sivaraj et al.

JOURNAL OF CLUSTER SCIENCE (2020)

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Article Chemistry, Multidisciplinary

Macrophage-Targeted Isoniazid-Selenium Nanoparticles Promote Antimicrobial Immunity and Synergize Bactericidal Destruction of Tuberculosis Bacilli

Jiang Pi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Article Biochemistry & Molecular Biology

Green synthesis of quaternized chitosan/silver nanocomposites for targeting mycobacterium tuberculosis and lung carcinoma cells (A-549)

Marwa M. Abdel-Aziz et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Biochemistry & Molecular Biology

Fungicidal and anti-biofilm activities of trimethylchitosan-stabilized silver nanoparticles against Candida species in zebrafish embryos

Shao-Hung Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Biochemistry & Molecular Biology

Phyto-fabricated ZnO nanoparticles from Canthium dicoccum (L.) for antimicrobial, anti-tuberculosis and antioxidant activity

C. Mahendra et al.

PROCESS BIOCHEMISTRY (2020)

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Article Infectious Diseases

Rehabilitation, optimized nutritional care, and boosting host internal milieu to improve long-term treatment outcomes in tuberculosis patients

Onno W. Akkerman et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

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Article Nanoscience & Nanotechnology

Novel Approach for Transdermal Delivery of Rifampicin to Induce Synergistic Antimycobacterial Effects Against Cutaneous and Systemic Tuberculosis Using a Cationic Nanoemulsion Gel

Afzal Hussain et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

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Review Nanoscience & Nanotechnology

The Antibacterial Mechanism of Silver Nanoparticles and Its Application in Dentistry

Iris Xiaoxue Yin et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

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Article Chemistry, Multidisciplinary

In Vivo Biodistribution of Respirable Solid Lipid Nanoparticles Surface-Decorated with a Mannose-Based Surfactant: A Promising Tool for Pulmonary Tuberculosis Treatment?

Eleonora Truzzi et al.

NANOMATERIALS (2020)

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Review Microbiology

The Pathogenesis of Tuberculosis-The Koch Phenomenon Reinstated

Robert L. Hunter

PATHOGENS (2020)

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Review Respiratory System

Treatment of Isoniazid-Resistant Pulmonary Tuberculosis

Byung Woo Jhun et al.

TUBERCULOSIS AND RESPIRATORY DISEASES (2020)

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Article Chemistry, Medicinal

Inhalable liposomes of Glycyrrhiza glabra extract for use in tuberculosis: formulation, in vitro characterization, in vivo lung deposition, and in vivo pharmacodynamic studies

Vivek Viswanathan et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2019)

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Review Microbiology

Mycobacterium tuberculosis infection of host cells in space and time

Claudio Bussi et al.

FEMS MICROBIOLOGY REVIEWS (2019)

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Article Infectious Diseases

Analysis of drug resistance mutations in pulmonary Mycobacterium tuberculosis isolates in the Southern coastal region of Andhra Pradesh, India

Giri Prasad Polu et al.

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES (2019)

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Article Pharmacology & Pharmacy

Alginate modified-PLGA nanoparticles entrapping amikacin and moxifloxacin as a novel host-directed therapy for multidrug-resistant tuberculosis

Sharif Abdelghany et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

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Article Chemistry, Multidisciplinary

Polymeric nanobiotics as a novel treatment for mycobacterial infections

Iris L. Batalha et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Infectious Diseases

The Anti-Mycobacterial Activity Of Ag, ZnO, And Ag- ZnO Nanoparticles Against MDR- And XDR-Mycobacterium tuberculosis

Mohsen Heidary et al.

INFECTION AND DRUG RESISTANCE (2019)

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Review Infectious Diseases

Advances in the understanding of Mycobacterium tuberculosis transmission in HIV-endemic settings

Julian S. Peters et al.

LANCET INFECTIOUS DISEASES (2019)

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Article Materials Science, Biomaterials

Size-dependent antimycobacterial activity of titanium oxide nanoparticles against Mycobacterium tuberculosis

Vaikundamoorthy Ramalingam et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Article Engineering, Biomedical

Magnetic iron oxide nanoparticles (MIONs) cross-linked natural polymer-based hybrid gel beads: Controlled nano anti-TB drug delivery application

Mookkandi Palsamy Kesavan et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2018)

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Article Chemistry, Multidisciplinary

Multimetallic Microparticles Increase the Potency of Rifampicin against Intracellular Mycobacterium tuberculosis

Timothy Ellis et al.

ACS NANO (2018)

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Article Biophysics

Heteroassembled gold nanoparticles with sandwich-immunoassay LSPR chip format for rapid and sensitive detection of hepatitis B virus surface antigen (HBsAg)

Jinwoon Kim et al.

BIOSENSORS & BIOELECTRONICS (2018)

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Article Biochemistry & Molecular Biology

Chondroitin sulfate-stabilized silver nanoparticles: Improved synthesis and their catalytic, antimicrobial, and biocompatible activities

Jenn-jong Young et al.

CARBOHYDRATE RESEARCH (2018)

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Article Engineering, Environmental

New active formulations against M. tuberculosis: Bedaquiline encapsulation in lipid nanoparticles and chitosan nanocapsules

L. De Matteis et al.

CHEMICAL ENGINEERING JOURNAL (2018)

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Article Biochemistry & Molecular Biology

Silver nanoparticle functionalized CS-g-(CA-MA-PZA) carrier for sustainable anti-tuberculosis drug delivery

Rajendran Arnarnath Praphakar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

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Article Infectious Diseases

Global tuberculosis targets and milestones set for 2016-2035: definition and rationale

K. Floyd et al.

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2018)

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Article Pharmacology & Pharmacy

Mannosylated gelatin nanoparticles of licorice for use in tuberculosis: Formulation, in vitro evaluation, in vitro cell uptake, in vivo pharmacokinetics and in vivo anti-tubercular efficacy

Vivek Viswanathan et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2018)

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Article Chemistry, Multidisciplinary

Functional silica nanoparticles conjugated with beta-glucan to deliver anti-tuberculosis drug molecules

Jangsun Hwang et al.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2018)

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Article Infectious Diseases

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Susan E. Dorman et al.

LANCET INFECTIOUS DISEASES (2018)

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Article Biotechnology & Applied Microbiology

Functional nanocarrier for drug and gene delivery via local administration in mucosal tissues

Lingwei Wang et al.

NANOMEDICINE (2018)

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Review Critical Care Medicine

The global tuberculosis epidemic and progress in care, prevention, and research: an overview in year 3 of the End TB era

Katherine Floyd et al.

LANCET RESPIRATORY MEDICINE (2018)

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Article Chemistry, Medicinal

Formulation, optimization, and characterization of rifampicin-loaded solid lipid nanoparticles for the treatment of tuberculosis

Nimitt V. Chokshi et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2018)

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Review Pharmacology & Pharmacy

Dendrimers: A versatile nanocarrier for drug delivery and targeting

Atul P. Sherje et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Review Chemistry, Multidisciplinary

Nanotechnology in Tuberculosis: State of the Art and the Challenges Ahead

Estefania Grotz et al.

PHARMACEUTICAL RESEARCH (2018)

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Review Biochemistry & Molecular Biology

Inorganic Nanoparticles for Cancer Therapy: A Transition from Lab to Clinic

Samer Bayda et al.

CURRENT MEDICINAL CHEMISTRY (2018)

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Letter Respiratory System

Pyridoxine for patients suffering from drug-susceptible tuberculosis in India

M. Bhargava et al.

PUBLIC HEALTH ACTION (2018)

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Review Infectious Diseases

Imaging in extrapulmonary tuberculosis

Sanjay Gambhir et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2017)

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Article Pharmacology & Pharmacy

Preparation and characterization of isoniazid-loaded crude soybean lecithin liposomes

Christian Isalomboto Nkanga et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Pharmacology & Pharmacy

Chitosan and hyaluronan coated liposomes for pulmonary administration of curcumin

Maria Manconi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Immunology

Drivers of Tuberculosis Transmission

Barun Mathema et al.

JOURNAL OF INFECTIOUS DISEASES (2017)

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Article Immunology

What We Know About Tuberculosis Transmission: An Overview

Gavin Churchyard et al.

JOURNAL OF INFECTIOUS DISEASES (2017)

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Article Biochemical Research Methods

A label-free biosensor based on localized surface plasmon resonance for diagnosis of tuberculosis

Wenxia Sun et al.

JOURNAL OF MICROBIOLOGICAL METHODS (2017)

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Article Medicine, General & Internal

Side effects associated with the treatment of multidrug-resistant tuberculosis at a tuberculosis referral hospital in South Korea A retrospective study

Tae Won Yang et al.

MEDICINE (2017)

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Article Immunology

Bactericidal impact of Ag, ZnO and mixed AgZnO colloidal nanoparticles on H37Rv Mycobacterium tuberculosis phagocytized by THP-1 cell lines

Alireza Jafari et al.

MICROBIAL PATHOGENESIS (2017)

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Article Immunology

Antigen 85 complex as a powerful Mycobacterium tuberculosis immunogene: Biology, immune-pathogenicity, applications in diagnosis, and vaccine design

Mohsen Karbalaei Zadeh Babaki et al.

MICROBIAL PATHOGENESIS (2017)

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Article Radiology, Nuclear Medicine & Medical Imaging

Pulmonary Tuberculosis: Role of Radiology in Diagnosis and Management

Arun C. Nachiappan et al.

RADIOGRAPHICS (2017)

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Review Chemistry, Analytical

Biosensing Using Magnetic Particle Detection Techniques

Yi-Ting Chen et al.

SENSORS (2017)

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Article Microbiology

The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

Soumitesh Chakravorty et al.

MBIO (2017)

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Review Materials Science, Biomaterials

Recent developments in the synthesis, properties, and biomedical applications of core/shell superparamagnetic iron oxide nanoparticles with gold

Sandip Sabale et al.

BIOMATERIALS SCIENCE (2017)

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Review Nanoscience & Nanotechnology

Emerging applications of label-free optical biosensors

Giuliano Zanchetta et al.

NANOPHOTONICS (2017)

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Article Chemistry, Multidisciplinary

Diagnosis of Tuberculosis Using Colorimetric Gold Nanoparticles on a Paper-Based Analytical Device

Tsung-Ting Tsai et al.

ACS SENSORS (2017)

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Article Multidisciplinary Sciences

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

Joana Costa-Gouveia et al.

SCIENTIFIC REPORTS (2017)

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Article Biophysics

Trimethyl chitosan-capped silver nanoparticles with positive surface charge: Their catalytic activity and antibacterial spectrum including multidrug-resistant strains of Acinetobacter baumannii

T. Y. Chang et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

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Review Medicine, General & Internal

Clinical use of whole genome sequencing for Mycobacterium tuberculosis

Adam A. Witney et al.

BMC MEDICINE (2016)

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Review Pharmacology & Pharmacy

Mechanism of isoniazid-induced hepatotoxicity: then and now

Imir Metushi et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2016)

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Review Biochemistry & Molecular Biology

Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

Xi-Feng Zhang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

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Review Chemistry, Multidisciplinary

Surface Modification Chemistries of Materials Used in Diagnostic Platforms with Biomolecules

Mukesh Digambar Sonawane et al.

JOURNAL OF CHEMISTRY (2016)

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Review Pharmacology & Pharmacy

Isoniazid metabolism and hepatotoxicity

Pengcheng Wang et al.

ACTA PHARMACEUTICA SINICA B (2016)

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Article Multidisciplinary Sciences

GenoType MTBDRplus Assay for Rapid Detection of Multidrug Resistance in Mycobacterium tuberculosis: A Meta-Analysis

Yuanyuan Bai et al.

PLOS ONE (2016)

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Review Medicine, General & Internal

Gold Nanoparticles for Diagnostics: Advances towards Points of Care

Milton Cordeiro et al.

DIAGNOSTICS (2016)

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Article Infectious Diseases

Limonia acidissima L. leaf mediated synthesis of zinc oxide nanoparticles: A potent tool against Mycobacterium tuberculosis

Tarikere C. Taranath et al.

INTERNATIONAL JOURNAL OF MYCOBACTERIOLOGY (2016)

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Review Pharmacology & Pharmacy

Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and Challenges

Hong Wen et al.

AAPS JOURNAL (2015)

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Article Engineering, Chemical

Smart nanoparticles for drug delivery: Boundaries and opportunities

Byung Kook Lee et al.

CHEMICAL ENGINEERING SCIENCE (2015)

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Article Immunology

The Distribution of Fitness Costs of Resistance-Conferring Mutations Is a Key Determinant for the Future Burden of Drug-Resistant Tuberculosis: A Model-Based Analysis

Gwenan M. Knight et al.

CLINICAL INFECTIOUS DISEASES (2015)

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Editorial Material Gastroenterology & Hepatology

Pancreatic tuberculosis: Look at the kidney!

Vishal Sharma et al.

DIGESTIVE AND LIVER DISEASE (2015)

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Review Pharmacology & Pharmacy

Nano- and micro-based inhaled drug delivery systems for targeting alveolar macrophages

Wing-Hin Lee et al.

EXPERT OPINION ON DRUG DELIVERY (2015)

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Article Infectious Diseases

Chemical and biological metal nanoparticles as antimycobacterial agents: A comparative study

Richa Singh et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2015)

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Editorial Material Infectious Diseases

Multifocal Cutaneous and Osseous Tuberculosis

M. M. Sherif et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2015)

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Review Infectious Diseases

The complex evolution of antibiotic resistance in Mycobacterium tuberculosis

J. D. Fonseca et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2015)

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Article Pharmacology & Pharmacy

Novel perspectives in the tuberculosis treatment: Administration of isoniazid through the skin

Thiago Caon et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

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Review Microbiology

Mycobacterium tuberculosis: ecology and evolution of a human bacterium

Anne-Laure Banuls et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2015)

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Article Biochemical Research Methods

Association of the anti-tuberculosis drug rifampicin with a PAMAM dendrimer

Reinaldo G. Bellini et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2015)

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Article Multidisciplinary Sciences

Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification

Srijata Sarkar et al.

PLOS ONE (2015)

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Article Chemistry, Multidisciplinary

pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice

Angela A. Hwang et al.

SMALL (2015)

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Article Microbiology

Comparative analysis of pulmonary and extrapulmonary tuberculosis of 411 cases

Aysel Sunnetcioglu et al.

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS (2015)

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Article Medicine, Research & Experimental

Imaging in Tuberculosis

Jamshed B. Bomanji et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)

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Article Medicine, Research & Experimental

Multidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis

Kwonjune J. Seung et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)

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Article Genetics & Heredity

Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Francesc Coll et al.

GENOME MEDICINE (2015)

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Review Pharmacology & Pharmacy

A review on phospholipids and their main applications in drug delivery systems

Jing Li et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)

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Article Medicine, General & Internal

Evaluation of Pulmonary and Extrapulmonary Tuberculosis in Immunocompetent Adults: A Retrospective Case Series Analysis

Selma Ates Guler et al.

MEDICAL PRINCIPLES AND PRACTICE (2015)

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Article Biochemistry & Molecular Biology

Mutation of environmental mycobacteria to resist silver nanoparticles also confers resistance to a common antibiotic

Curtis Larimer et al.

BIOMETALS (2014)

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Article Chemistry, Multidisciplinary

Thiol-modified gold nanoparticles for the inhibition of Mycobacterium smegmatis

Jennifer C. Gifford et al.

CHEMICAL COMMUNICATIONS (2014)

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Review Biochemistry & Molecular Biology

Drug targeting using solid lipid nanoparticles

Elham Rostami et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2014)

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Review Biochemistry & Molecular Biology

Nanoparticle-Mediated Pulmonary Drug Delivery: A Review

Mukta Paranjpe et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

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Article Pharmacology & Pharmacy

Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis

Eleonora Maretti et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)

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Article Chemistry, Multidisciplinary

Polyacrylic Acid-Coated Iron Oxide Nanoparticles for Targeting Drug Resistance in Mycobacteria

Priyanka Padwal et al.

LANGMUIR (2014)

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Article Multidisciplinary Sciences

A Multi-Site Validation in India of the Line Probe Assay for the Rapid Diagnosis of Multi-Drug Resistant Tuberculosis Directly from Sputum Specimens

Neeraj Raizada et al.

PLOS ONE (2014)

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Review Biology

The ongoing challenge of latent tuberculosis

H. Esmail et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

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Article Pharmacology & Pharmacy

Single step spray drying method to develop proliposomes for inhalation: A systematic study based on quality by design approach

Arpana Patil-Gadhe et al.

PULMONARY PHARMACOLOGY & THERAPEUTICS (2014)

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Article Nanoscience & Nanotechnology

One-Pot Construction of Functional Mesoporous Silica Nanoparticles for the Tumor-Acidity-Activated Synergistic Chemotherapy of Glioblastoma

Ze-Yong Li et al.

ACS APPLIED MATERIALS & INTERFACES (2013)

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Article Microbiology

Cationic Antimicrobial Peptides and Biogenic Silver Nanoparticles Kill Mycobacteria without Eliciting DNA Damage and Cytotoxicity in Mouse Macrophages

Soumitra Mohanty et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)

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Article Microbiology

Gallium Nitrate Is Efficacious in Murine Models of Tuberculosis and Inhibits Key Bacterial Fe-Dependent Enzymes

Oyebode Olakanmi et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)

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Article Biophysics

Bio-microfluidic platform for gold nanoprobe based DNA detection-application to Mycobacterium tuberculosis

Iwona Bernacka-Wojcik et al.

BIOSENSORS & BIOELECTRONICS (2013)

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Editorial Material Respiratory System

Tuberculosis: are we making it incurable?

Jose A. Caminero et al.

EUROPEAN RESPIRATORY JOURNAL (2013)

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Article Immunology

Enhanced protection against pulmonary mycobacterial challenge by chitosan-formulated polyepitope gene vaccine is associated with increased pulmonary secretory IgA and gamma-interferon plus T cell responses

Wenqing Ai et al.

MICROBIOLOGY AND IMMUNOLOGY (2013)

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Article Multidisciplinary Sciences

Detection of Rifampicin Resistance in Mycobacterium tuberculosis by Padlock Probes and Magnetic Nanobead-Based Readout

Anna Engstrom et al.

PLOS ONE (2013)

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Article Chemistry, Analytical

Rapid monitoring of CFP-10 during culture of Mycobacterium tuberculosis by using a magnetophoretic immunoassay

Jeonghyo Kim et al.

SENSORS AND ACTUATORS B-CHEMICAL (2013)

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Article Immunology

Enhancement of immune response to a DNA vaccine against Mycobacterium tuberculosis Ag85B by incorporation of an autophagy inducing system

Jomkhwan Meerak et al.

VACCINE (2013)

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Article Multidisciplinary Sciences

Magnetic barcode assay for genetic detection of pathogens

Monty Liong et al.

NATURE COMMUNICATIONS (2013)

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Review Pediatrics

Pharmacokinetics of Antibacterial Agents in the CSF of Children and Adolescents

Amanda K. Sullins et al.

PEDIATRIC DRUGS (2013)

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Review Immunology

Virulence factors of the Mycobacterium tuberculosis complex

Marina A. Forrellad et al.

VIRULENCE (2013)

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Review Gastroenterology & Hepatology

Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management

Vidyasagar Ramappa et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2013)

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Article Microbiology

Targeted Intracellular Delivery of Antituberculosis Drugs to Mycobacterium tuberculosis-Infected Macrophages via Functionalized Mesoporous Silica Nanoparticles

Daniel L. Clemens et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)

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Article Engineering, Chemical

CHARACTERIZATION OF LYOPHILIZED LIPOSOMES PRODUCED WITH NON-PURIFIED SOY LECITHIN: A CASE STUDY OF CASEIN HYDROLYSATE MICROENCAPSULATION

D. Yokota et al.

BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING (2012)

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Review Biochemical Research Methods

Achievements and future trends in the analysis of emerging organic contaminants in environmental samples by mass spectrometry and bioanalytical techniques

Marinella Farre et al.

JOURNAL OF CHROMATOGRAPHY A (2012)

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Review Chemistry, Multidisciplinary

Vaccination Strategies against Malaria: novel carrier(s) more than a tour de force

Rajeev K. Tyagi et al.

JOURNAL OF CONTROLLED RELEASE (2012)

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Article Biochemical Research Methods

Gold on paper-paper platform for Au-nanoprobe TB detection

Bruno Veigas et al.

LAB ON A CHIP (2012)

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Article Nanoscience & Nanotechnology

Nanoparticle-based adjuvant for enhanced protective efficacy of DNA vaccine Ag85A-ESAT-6-IL-21 against Mycobacterium tuberculosis infection

Fangliu Yu et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2012)

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Article Nanoscience & Nanotechnology

Silver nanoparticle enhanced silver ion stress response in Escherichia coli K12

Jonathan S. McQuillan et al.

NANOTOXICOLOGY (2012)

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Article Multidisciplinary Sciences

Formulation of a mmaA4 Gene Deletion Mutant of Mycobacterium bovis BCG in Cationic Liposomes Significantly Enhances Protection against Tuberculosis

Steven C. Derrick et al.

PLOS ONE (2012)

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Article Multidisciplinary Sciences

How Staphylococcus aureus biofilms develop their characteristic structure

Saravanan Periasamy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

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Article Gastroenterology & Hepatology

A Guide to the Management of Tuberculosis in Patients with Chronic Liver Disease

Radha K. Dhiman et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2012)

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Review Microbiology

Mycobacterium tuberculosis: success through dormancy

Martin Gengenbacher et al.

FEMS MICROBIOLOGY REVIEWS (2012)

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Article Microbiology

Quorum sensing in biofilms - How to destroy the bacterial citadels or their cohesion/power?

Veronica Lazar

ANAEROBE (2011)

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Article Biophysics

Portable optoelectronic biosensing platform for identification of mycobacteria from the Mycobacterium tuberculosis complex

Leonardo Bione Silva et al.

BIOSENSORS & BIOELECTRONICS (2011)

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Article Biochemistry & Molecular Biology

Engineered ZnO and TiO2 nanoparticles induce oxidative stress and DNA damage leading to reduced viability of Escherichia coli

Ashutosh Kumar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

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Article Biochemistry & Molecular Biology

Isoniazid Proliposome Powders for Inhalation-Preparation, Characterization and Cell Culture Studies

Wipaporn Rojanarat et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2011)

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Article Chemistry, Multidisciplinary

Size-Dependent Bacterial Growth Inhibition and Mechanism of Antibacterial Activity of Zinc Oxide Nanoparticles

Krishna R. Raghupathi et al.

LANGMUIR (2011)

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Article Medicine, Research & Experimental

Comparison of the Depot Effect and Immunogenicity of Liposomes Based on Dimethyldioctadecylammonium (DDA), 3 beta[N ',N '-Dimethylaminoethane)carbomyl] Cholesterol (DC-Chol), and 1,2-Dioleoyl-3-trimethylammonium Propane (DOTAP): Prolonged Liposome Retention Mediates Stronger Th1 Responses

Malou Henriksen-Lacey et al.

MOLECULAR PHARMACEUTICS (2011)

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Article Polymer Science

Effects of PEGylation on the Size and Internal Structure of Dendrimers: Self-Penetration of Long PEG Chains into the Dendrimer Core

Hwankyu Lee et al.

MACROMOLECULES (2011)

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Article Nanoscience & Nanotechnology

Targeted anticancer prodrug with mesoporous silica nanoparticles as vehicles

Jianquan Fan et al.

NANOTECHNOLOGY (2011)

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Review Radiology, Nuclear Medicine & Medical Imaging

Extrapulmonary Tuberculosis: Radiological Imaging of an Almost Forgotten Transformation Artist

T. Heye et al.

ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN (2011)

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Review Microbiology

Mycobacterium tuberculosis infection and inflammation: what is beneficial for the host and for the bacterium?

Smitha J. Sasindran et al.

FRONTIERS IN MICROBIOLOGY (2011)

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Review Pharmacology & Pharmacy

New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery

Alejandro Sosnik et al.

ADVANCED DRUG DELIVERY REVIEWS (2010)

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Review Biotechnology & Applied Microbiology

Advances in developing HIV-1 viral load assays for resource-limited settings

ShuQi Wang et al.

BIOTECHNOLOGY ADVANCES (2010)

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Editorial Material Infectious Diseases

Pott's spine with 'bird nest' appearance

Vinay Ramakrishna Pandit et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2010)

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Review Infectious Diseases

Extrapulmonary tuberculosis in Kabul, Afghanistan: A hospital-based retrospective review

Tim Fader et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2010)

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Article Pharmacology & Pharmacy

Gelatin nanocarriers as potential vectors for effective management of tuberculosis

Gaurav Kant Saraogi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2010)

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Review Microbiology

Nanobead-based interventions for the treatment and prevention of tuberculosis

Gareth Griffiths et al.

NATURE REVIEWS MICROBIOLOGY (2010)

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Review Immunology

The near future: Improving the activity of rifamycins and pyrazinamide

D. A. Mitchison et al.

TUBERCULOSIS (2010)

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Article Chemistry, Multidisciplinary

Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs

Tian Xia et al.

ACS NANO (2009)

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Review Biophysics

Detection of microorganisms using biosensors-A smarter way towards detection techniques

Madhura Nayak et al.

BIOSENSORS & BIOELECTRONICS (2009)

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Review Engineering, Biomedical

Surface-Engineered Dendrimers: a Solution for Toxicity Issues

Vijay Mishra et al.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2009)

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Article Engineering, Biomedical

Chitosan-based rechargeable long-term antimicrobial and biofilm-controlling systems

Zhengbing Cao et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2009)

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Article Biochemical Research Methods

Direct detection of unamplified DNA from pathogenic mycobacteria using DNA-derivatized gold nanoparticles

Emmanouil Liandris et al.

JOURNAL OF MICROBIOLOGICAL METHODS (2009)

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Article Biochemistry & Molecular Biology

Synthetic EthR inhibitors boost antituberculous activity of ethionamide

Nicolas Willand et al.

NATURE MEDICINE (2009)

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Review Microbiology

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

Clifton E. Barry et al.

NATURE REVIEWS MICROBIOLOGY (2009)

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Article Multidisciplinary Sciences

CD4 and CD8 T Cell Responses to the M. tuberculosis Ag85B-TB10.4 Promoted by Adjuvanted Subunit, Adenovector or Heterologous Prime Boost Vaccination

Tara Elvang et al.

PLOS ONE (2009)

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Article Multidisciplinary Sciences

A Novel Liposome-Based Adjuvant CAF01 for Induction of CD8+ Cytotoxic T-Lymphocytes (CTL) to HIV-1 Minimal CTL Peptides in HLA-A*0201 Transgenic Mice

Gregers Jacob Gram et al.

PLOS ONE (2009)

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Review Biotechnology & Applied Microbiology

Acoustic wave biosensors: physical models and biological applications of quartz crystal microbalance

Guilherme N. M. Ferreira et al.

TRENDS IN BIOTECHNOLOGY (2009)

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Article Immunology

Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice

Maytal Bivas-Benita et al.

VACCINE (2009)

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Review Chemistry, Analytical

Sensitive optical biosensors for unlabeled targets: A review

Xudong Fan et al.

ANALYTICA CHIMICA ACTA (2008)

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Article Infectious Diseases

Comparison of pulmonary and extrapulmonary tuberculosis in Nepal - a hospital-based retrospective study

Chandrashekhar T. Sreeramareddy et al.

BMC INFECTIOUS DISEASES (2008)

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Article Infectious Diseases

Diagnosis of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis: Current standards and challenges

Giovanni Battista Migliori et al.

CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY (2008)

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Review Infectious Diseases

Multildrug-resistant and extensively drug-resistant tuberculosis: a review

Edward D. Chan et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2008)

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Review Chemistry, Multidisciplinary

Potential of solid lipid nanoparticles in brain targeting

Indu Pal Kaur et al.

JOURNAL OF CONTROLLED RELEASE (2008)

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Article Multidisciplinary Sciences

Cationic Liposomes Formulated with Synthetic Mycobacterial Cordfactor (CAF01): A Versatile Adjuvant for Vaccines with Different Immunological Requirements

Else Marie Agger et al.

PLOS ONE (2008)

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Article Pathology

Lung granulomas from Mycobacterium tuberculosis/HIV-1 co-infected patients display decreased in situ TNF production

Almerio L. L. de Noronha et al.

PATHOLOGY RESEARCH AND PRACTICE (2008)

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Article Engineering, Environmental

The inhibitory effects of silver nanoparticles, silver ions, and silver chloride colloids on microbial growth

Okkyoung Choi et al.

WATER RESEARCH (2008)

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Review Biochemical Research Methods

Gold nanoparticles for the development of clinical diagnosis methods

Pedro Baptista et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2008)

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Article Pharmacology & Pharmacy

Encapsulation of moxifloxacin within poly(butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis

K. O. Kisich et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

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Review Biotechnology & Applied Microbiology

Nanoparticles for drug delivery to the lungs

Jean C. Sung et al.

TRENDS IN BIOTECHNOLOGY (2007)

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Review Biophysics

Nanomaterials and nanoparticles: Sources and toxicity

Cristina Buzea et al.

BIOINTERPHASES (2007)

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Article Pharmacology & Pharmacy

Inhalable microparticles containing large payload of anti-tuberculosis drugs

Pavan Muttil et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2007)

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Article Pharmacology & Pharmacy

Effects of Labrasol and other pharmaceutical excipients on the intestinal transport and absorption of rhodamine123, a P-glycoprotein substrate, in rats

Yulian Lin et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2007)

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Article Chemistry, Multidisciplinary

Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings

Hongwei Duan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

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Article Infectious Diseases

Uptake of inhalable microparticles affects defence responses of macrophages infected with Mycobacterium tuberculosis H37Ra

Rolee Sharma et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)

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Article Oncology

Nanoparticle-based oral drug delivery system for an injectable antibiotic - Streptomycin - Evaluation in a murine tuberculosis model

Rajesh Pandey et al.

CHEMOTHERAPY (2007)

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Review Biotechnology & Applied Microbiology

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

Christopher J. H. Porter et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

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Article Chemistry, Analytical

Hydrothermal synthesis of highly crystalline ZnO nanoparticles: A competitive sensor for LPG and EtOH

Babita Baruwati et al.

SENSORS AND ACTUATORS B-CHEMICAL (2006)

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Article Pharmacology & Pharmacy

Preparation of a claudin-targeting molecule using a C-terminal fragment of Clostridium perfringens enterotoxin

C Ebihara et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

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Article Critical Care Medicine

The potential advantages of nanoparticle drug delivery systems in chemotherapy of tuberculosis

S Gelperina et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

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Article Immunology

Solid lipid particle-based inhalable sustained drug delivery system against experimental tuberculosis

R Pandey et al.

TUBERCULOSIS (2005)

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Article Biotechnology & Applied Microbiology

Studies on PEGylated and drug-loaded PAMAM dendrimers

GF Pan et al.

JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS (2005)

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Article Infectious Diseases

Chemotherapeutic potential of alginate-chitosan microspheres as anti-tubercular drug carriers

R Pandey et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2004)

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Article Pharmacology & Pharmacy

Solid lipid namoparticles (SLNs) to improve oral bioavailability of poorly soluble drugs

LD Hu et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2004)

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Article Chemistry, Multidisciplinary

Altered chemical and biological activities of all-trans retinoic acid incorporated in solid lipid nanoparticle powders

SJ Lim et al.

JOURNAL OF CONTROLLED RELEASE (2004)

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Article Chemistry, Multidisciplinary

Silica particles:: A novel drug-delivery system

C Barbé et al.

ADVANCED MATERIALS (2004)

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Article Infectious Diseases

Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis

A Sharma et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2004)

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Review Biochemical Research Methods

Present and future of surface plasmon resonance biosensors

J Homola

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2003)

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Article Chemistry, Medicinal

Commonly used surfactant, tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats

HJ Zhang et al.

ARCHIVES OF PHARMACAL RESEARCH (2003)

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Article Microbiology

Chemotherapeutic potential of orally administered poly(lactide-co-glycolide) microparticles containing isoniazid, rifampin, and pyrazinamide against experimental tuberculosis

Q ul-Ain et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)

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Review Cell Biology

Phagocytosis: latex leads the way

M Desjardins et al.

CURRENT OPINION IN CELL BIOLOGY (2003)

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Article Infectious Diseases

Alginate-based oral drug delivery system for tuberculosis: pharmacokinetics and therapeutic effects

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