4.7 Article

Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through an ROS-dependent mechanism

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer

Johanna M. Buschhaus et al.

Summary: Research has found that ER+ breast cancer cells in direct contact with MSCs acquire cancer stem-like phenotypes and develop resistance to antiestrogenic drugs. It has also been observed that modulating iron levels can restore sensitivity to antiestrogenic therapy. These findings provide a new strategy for treating ER+ breast cancer.

ONCOGENE (2022)

Review Cell Biology

Regulation of Mitochondrial Function by the Actin Cytoskeleton

Maria Illescas et al.

Summary: This mini-review summarizes the regulatory role of actin cytoskeleton and actin-binding proteins (ABPs) on mitochondrial function, with a focus on the involvement of Gelsolin in mitochondrial disorders. The functional interplay between actin cytoskeleton, ABPs, and mitochondrial membranes for the regulation of cellular homeostasis is highlighted as a new exciting field for future research and therapeutic approaches.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Cell Biology

The phosphatase Shp1 interacts with and dephosphorylates cortactin to inhibit invadopodia function

Alessia Varone et al.

Summary: The research demonstrated that Shp1 plays a crucial role in invadopodia formation by promoting the dephosphorylation of cortactin, thereby reducing melanoma cancer cells' ability to degrade the extracellular matrix. Additionally, the study showed that Shp1 can be considered as a regulator of melanoma cell invasiveness and a potential target for antimetastatic drugs. Glycerophosphoinositol was found to facilitate the localization of Shp1 at invadopodia, leading to impaired invadopodia function and decreased tumor dissemination both in vitro and in an in vivo model of melanomas.

CELL COMMUNICATION AND SIGNALING (2021)

Review Biotechnology & Applied Microbiology

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

Henry Jay Forman et al.

Summary: Oxidative stress plays a role in various diseases, and understanding the mechanisms behind antioxidants and how to enhance antioxidant defences may lead to greater pharmacological success.

NATURE REVIEWS DRUG DISCOVERY (2021)

Review Biochemistry & Molecular Biology

The Mitochondrion as an Emerging Therapeutic Target in Cancer

Katherine G. Roth et al.

TRENDS IN MOLECULAR MEDICINE (2020)

Review Oncology

Shp1 in Solid Cancers and Their Therapy

Alessia Varone et al.

FRONTIERS IN ONCOLOGY (2020)

Review Pharmacology & Pharmacy

On the Clinical Pharmacology of Reactive Oxygen Species

Ana Casas et al.

PHARMACOLOGICAL REVIEWS (2020)

Review Biochemistry & Molecular Biology

Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy

Tzu-Ting Huang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Cell Biology

ROS and ROS-Mediated Cellular Signaling

Jixiang Zhang et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Article Multidisciplinary Sciences

A neuronal network of mitochondrial dynamics regulates metastasis

M. Cecilia Caino et al.

NATURE COMMUNICATIONS (2016)

Review Cell Biology

Functions of Shp2 in cancer

Jie Zhang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2015)

Review Oncology

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

Go J. Yoshida

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)

Article Multidisciplinary Sciences

Oxidative stress inhibits distant metastasis by human melanoma cells

Elena Piskounova et al.

NATURE (2015)

Article Multidisciplinary Sciences

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

M. Cecilia Caino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion

Dayana B. Rivadeneira et al.

SCIENCE SIGNALING (2015)

Article Biochemistry & Molecular Biology

Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion

Dayana B. Rivadeneira et al.

SCIENCE SIGNALING (2015)

Review Oncology

Mitochondrial reactive oxygen species and cancer

Lucas B. Sullivan et al.

CANCER & METABOLISM (2014)

Article Biochemistry & Molecular Biology

Mitochondria: Starving to reach quorum?

Martin Picard et al.

BIOESSAYS (2012)

Article Immunology

The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation

Katie E. Crump et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

In vivo imaging of ligand receptor binding with Gaussia luciferase cornplementation

Kathryn E. Luker et al.

NATURE MEDICINE (2012)

Article Pathology

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Matthew W. Conklin et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Article Oncology

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis

Emilie A. Bard-Chapeau et al.

CANCER CELL (2011)

Article Multidisciplinary Sciences

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. De Nicola et al.

NATURE (2011)

Review Biochemistry & Molecular Biology

Oxidative stress, inflammation, and cancer How are they linked?

Simone Reuter et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Review Cell Biology

Energetics, epigenetics, mitochondrial genetics

Douglas C. Wallace et al.

MITOCHONDRION (2010)

Article Multidisciplinary Sciences

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration

Koji Yo et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Article Biochemical Research Methods

Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7

Kathryn E. Luker et al.

BIOTECHNIQUES (2009)

Article Multidisciplinary Sciences

Association of reactive oxygen species levels and radioresistance in cancer stem cells

Maximilian Diehn et al.

NATURE (2009)

Review Physiology

Mitochondrial Dynamics in Mammalian Health and Disease

Marc Liesa et al.

PHYSIOLOGICAL REVIEWS (2009)

Article Cardiac & Cardiovascular Systems

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

Tianzheng Yu et al.

CARDIOVASCULAR RESEARCH (2008)

Article Biochemistry & Molecular Biology

A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

Jan Trnka et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Article Multidisciplinary Sciences

Mechanism of shape determination in motile cells

Kinneret Keren et al.

NATURE (2008)

Article Biochemical Research Methods

Lifeact: a versatile marker to visualize F-actin

Julia Riedl et al.

NATURE METHODS (2008)

Article Multidisciplinary Sciences

Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

TZ Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Oncology

CXCR4 regulates growth of both primary and metastatic breast cancer

MCP Smith et al.

CANCER RESEARCH (2004)

Article Biochemistry & Molecular Biology

The protein tyrosine phosphatase SHP-2 regulates interleukin-1-induced ERK activation in fibroblasts

M MacGillivray et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)