4.7 Article

Association of Antihistamine Use with Increased Risk of Esophageal Squamous Cell Carcinoma: A Nationwide, Long-Term Follow-Up Study Using Propensity Score Matching

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

The clinical relationship between histamine-1 receptor antagonists and risk of cancer: a systematic review and meta-analysis

Elham Bakhtiari et al.

Summary: Studies indicate that the use of antihistamines may reduce the risk of certain cancers, particularly in cases of glioma. Sensitivity and subgroup analysis suggest that omitting certain studies may alter the direction of the results. More research with defined background of allergy is needed to clarify the relevance of different types of cancer with anti-H1 receptors.

EXPERT REVIEW OF ANTICANCER THERAPY (2023)

Article Medicine, General & Internal

Dementia risk after major elective surgery based on the route of anaesthesia: A propensity score-matched population-based cohort study

Mingyang Sun et al.

Summary: This study compared the incidence of dementia among surgical patients undergoing different routes of anesthesia and found that patients undergoing general anesthesia had a higher risk of dementia compared to those undergoing regional anesthesia. The risk of dementia was also higher with inhalation anesthesia compared to noninhalation anesthesia. These findings should be confirmed in a randomized controlled trial.

ECLINICALMEDICINE (2023)

Article Endocrinology & Metabolism

with type 2 diabetes mellitus

Szu-Yuan Wu et al.

Summary: This study investigated the association between H1-antihistamine use and hepatocellular carcinoma (HCC) risk in type 2 diabetes mellitus (T2DM) patients without hepatitis B or C virus infection. The results showed that the use of antihistamines significantly reduced the risk of HCC in these patients, and a dose-response relationship was observed.

DIABETES & METABOLISM (2023)

Article Anesthesiology

Effect of opioids on cancer survival in patients with chronic pain: a propensity score-matched population-based cohort study

Mingyang Sun et al.

Summary: The study suggests that long-term opioid analgesic use before cancer diagnosis may be associated with poor overall survival in patients with chronic pain.

BRITISH JOURNAL OF ANAESTHESIA (2022)

Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Editorial Material Oncology

Antihistamines for cancer immunotherapy: More than just treating allergies

Song Chen et al.

Summary: The study identifies that histamine released during allergic reactions and from tumor cells weakens the response to immunotherapy. Histamine H-1-receptor signaling induces a suppressive phenotype in tumor-associated macrophages and increases VISTA expression, thereby suppressing CD8(+) T cell function. Anti-histamines can reverse these effects and improve the efficacy of immunotherapy.

CANCER CELL (2022)

Article Oncology

The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1

Hongzhong Li et al.

Summary: Antihistamines can improve survival in cancer patients by reversing T cell dysfunction through modulation of histamine receptor H1 (HRH1), thereby enhancing immunotherapy responses.

CANCER CELL (2022)

Article Oncology

H1-Antihistamines Reduce the Risk of Hepatocellular Carcinoma in Patients With Hepatitis B Virus, Hepatitis C Virus, or Dual Hepatitis B Virus-Hepatitis C Virus Infection

Yu-Chuan Shen et al.

Summary: This study suggests that H1-antihistamines may reduce the risk of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV), hepatitis C virus (HCV), or dual HBV-HCV infection. Patients using AHs had significantly lower risk of HCC compared to those who did not use AH, and there was a dose-response relationship observed.

JOURNAL OF CLINICAL ONCOLOGY (2022)

Article Anesthesiology

Association between long-term opioid use ana cancer risk in patients with chronic pain: a propensity score-matched cohort study

Mingyang Sun et al.

Summary: The study found an association between long-term opioid use and the development of cancer in patients with chronic pain, including multiple types of cancers. These results have important clinical implications.

BRITISH JOURNAL OF ANAESTHESIA (2022)

Article Nutrition & Dietetics

Sarcopenia as an Independent Risk Factor for Specific Cancers: A Propensity Score-Matched Asian Population-Based Cohort Study

Ming-Yang Sun et al.

Summary: Sarcopenia may be a significant risk factor for various types of cancer, including lung, colorectal, breast, head and neck, pancreas, gastric, esophageal, and ovarian cancers, as well as hepatocellular carcinoma. The study found that the presence of sarcopenia before cancer onset was associated with an increased risk of developing cancer. The adjusted incidence rate ratios for sarcopenia patients were particularly high for pancreatic cancer, esophageal cancer, and lung cancer.

NUTRIENTS (2022)

Article Chemistry, Medicinal

Possible Association between the Use of Proton Pump Inhibitors and H2 Receptor Antagonists, and Esophageal Cancer: A Nested Case-Control Study Using a Korean National Health Screening Cohort

Hyo Geun Choi et al.

Summary: This study investigated the likelihood of incident esophageal cancer and its mortality in Koreans, depending on prior history of PPI/H2RA use and GERD. The results showed that the use of PPI or H2RA was associated with an increased risk of incident esophageal cancer, while the use of PPI was associated with a decreased risk of mortality. However, the effect of H2RA varied depending on the presence of GERD and age.

PHARMACEUTICALS (2022)

Article Medicine, General & Internal

Long-term Incidence Rates of Esophageal Squamous Cell Carcinoma in Chinese Patients With Low-grade Intraepithelial Neoplasia and Association of Surveillance Endoscopy With Incidence

He Li et al.

Summary: This cohort study examines the incidence of esophageal squamous cell carcinoma (ESCC) and the use of surveillance endoscopy in patients with low-grade intraepithelial neoplasia in China.

JAMA NETWORK OPEN (2022)

Article Multidisciplinary Sciences

Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells

Nobuki Matsumoto et al.

Summary: Histamine H1 receptor antagonists selectively kill cisplatin-resistant cancer cells, possibly through a molecular mechanism involving autocrine histamine activity and high-level expression of FGF13. This suggests a potential opportunity to utilize H1 receptor antagonists in combination with anticancer agents to treat drug-resistant cancers effectively.

SCIENTIFIC REPORTS (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Toxicology

Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells

Sedat Kacar et al.

Summary: Cyproheptadine, a first-generation antihistamine drug, shows potential as an anticancer agent by increasing apoptosis and reducing inflammation levels. Further research on its mechanisms and efficacy in cancer treatment is warranted.

TOXICOLOGY IN VITRO (2021)

Article Gastroenterology & Hepatology

Association Between Metformin Use and Risk of Esophageal Squamous Cell Carcinoma in a Population-Based Cohort Study

Qiao-Li Wang et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2020)

Article Gastroenterology & Hepatology

Distinct roles of histamine H1-and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis

Zhongcheng Shi et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2019)

Article Gastroenterology & Hepatology

Association between proton pump inhibitors and the risk of hepatocellular carcinoma

Y. -H. J. Shao et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2018)

Article Gastroenterology & Hepatology

Epidemiology of Esophageal Squamous Cell Carcinoma

Christian C. Abnet et al.

GASTROENTEROLOGY (2018)

Article Medicine, Research & Experimental

Astemizole promotes the anti-tumor effect of vitamin D through inhibiting miR-125a-5p-meidated regulation of VDR in HCC

Junli Xu et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Editorial Material Gastroenterology & Hepatology

Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries

Maria Jose Domper Arnal et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Review Oncology

Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

Kyle J. Napier et al.

WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2014)

Article Medicine, General & Internal

Oesophageal carcinoma

Arjun Pennathur et al.

LANCET (2013)

Article Medicine, General & Internal

A 10-year experience with universal health insurance in Taiwan: Measuring changes in health and health disparity

Chi Pang Wen et al.

ANNALS OF INTERNAL MEDICINE (2008)

Review Allergy

H-1 Antihistamines Current Status and Future Directions

F. Estelle R. Simons et al.

WORLD ALLERGY ORGANIZATION JOURNAL (2008)

Article Gastroenterology & Hepatology

Use of anti-inflammatory drugs and lower esophageal sphincter-relaxing drugs and risk of esophageal and gastric cancers

Joan Fortuny et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2007)

Article Biochemistry & Molecular Biology

Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells

Nadia Lamplasi et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2007)