☆ 4.7 Review

Preprocedural Viral Load Effects of Oral Antiseptics on SARS-CoV-2 in Patients with COVID-19: A Systematic Review

BIOMEDICINES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Public, Environmental & Occupational Health

A pilot randomized trial to evaluate the efficacy of oral and nasal povidone iodine in reducing the burden of severe acute respiratory syndrome coronavirus 2 RNA in patients with coronavirus disease 2019

Sarah N. Redmond et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2023)

添加到收藏夹

Review Biochemistry & Molecular Biology

Current SARS-CoV-2 Protective Strategies for Healthcare Professionals

Miriam Ting et al.

Summary: This paper aims to provide healthcare professionals with evidence-based protective strategies against the transmission of SARS-CoV-2, including hand hygiene, surgical masks, vaccinations and boosters, air filtration, environmental sanitization, instrument sterilization, mouth rinses, and social distancing.

BIOMEDICINES (2023)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Is povidone iodine mouthwash effective against SARS-CoV-2? First in vivo tests

Lucia Martinez Lamas et al.

ORAL DISEASES (2022)

添加到收藏夹

Article Microbiology

CPC- containing oral rinses inactivate SARS- CoV-2 variants and are active in the presence of human saliva

Enyia R. Anderson et al.

Summary: This study examined the in vitro efficacy of mouthwash formulations in inactivating SARS-CoV-2 variants. The results showed that mouthwashes containing 0.07% cetylpyridinium chloride completely inactivated multiple SARS-CoV-2 variants and remained effective in the presence of human saliva.

JOURNAL OF MEDICAL MICROBIOLOGY (2022)

添加到收藏夹

Article Anatomy & Morphology

How does antiseptic mouthwashes against SARS-COV-2 affect the bond strength of universal adhesive to enamel?

Zumrut Ceren Ozduman et al.

Summary: This study compared the effect of different mouthwashes during the COVID-19 pandemic on the bond strength of universal adhesive to enamel. The results showed that in the self-etch mode, the group without mouthwash had significantly higher bond strength than other mouthwash groups; in the etch-and-rinse mode, teeth without mouthwash had significantly higher bond strength than the chlorhexidine and povidone-iodine groups.

MICROSCOPY RESEARCH AND TECHNIQUE (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Chlorhexidine mouthwash reduces the salivary viral load of SARS-CoV-2: A randomized clinical trial

Denis Damiao Costa et al.

Summary: The study found that using 0.12% chlorhexidine gluconate mouthwash significantly reduced the load of SARS-CoV-2 in saliva for at least 60 minutes.

ORAL DISEASES (2022)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Antiviral effect of mouthwashes against SARS-COV-2: A systematic review

Jhon Paul Iakov Mezarina Mendoza et al.

Summary: This systematic review evaluated the antiviral effect of mouthwashes against SARS-CoV-2 and found that povidone-iodine, cetylpyridinium chloride, and essential oils may have antiviral effects. However, more research is needed to confirm these findings.

SAUDI DENTAL JOURNAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses

Zack Saud et al.

Summary: The lipid envelope of SARS-CoV-2 is different from the host plasma membrane, which allows for selective antiviral approaches using oral rinses.

JOURNAL OF LIPID RESEARCH (2022)

添加到收藏夹

Article Environmental Sciences

Impact of Oral Rinsing with Octenidine Based Solution on SARS-CoV-2 Loads in Saliva of Infected Patients an Exploratory Study

Ralf Smeets et al.

Summary: This study investigated the in-vivo effect of an antiseptic mouth rinse with Octenisept plus phenoxyethanol (OCT + PE) on the oral SARS-CoV-2 load in COVID-19 patients. The results showed that mouth rinsing led to a significant reduction of SARS-CoV-2 RNA load in saliva immediately after rinsing, but the levels returned to baseline at later time points. The saliva samples remained infectious, as virus isolation was successful from samples collected at later time points.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

添加到收藏夹

Article Environmental Sciences

Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials

Alvaro Garcia-Sanchez et al.

Summary: The use of PVP-I as a pre-intervention mouthwash has been shown to reduce the salivary load of SARS-CoV-2, potentially decreasing the risk of cross-infection in healthcare settings.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

添加到收藏夹

Article Otorhinolaryngology

Efficacy of antiseptic mouthrinses against SARS-CoV-2: A prospective randomized placebo-controlled pilot study

Paolo Junior Fantozzi et al.

Summary: This study evaluated the effectiveness of three different mouthrinses in reducing oral/oropharyngeal SARS-CoV-2 viral load. The results showed that 1% povidone-iodine (PVP-I) rinse was the most effective, especially in patients with low viral copy numbers at baseline.

AMERICAN JOURNAL OF OTOLARYNGOLOGY (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Substantivity of mouth-rinse formulations containing cetylpyridinium chloride and O-cymen-5-ol: a randomized-crossover trial

Felipe-Rodrigo Aguilera et al.

Summary: This study aimed to evaluate the substantivity of mouth-washing solutions based on CPC and O-cymen-5-ol. The results showed that the combination of CPC and O-cymen-5-ol exhibited significant substantivity after 4 hours, making it a potential alternative to triclosan and chlorhexidine-based mouth-rinses.

BMC ORAL HEALTH (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Cetylpyridinium Chloride Mouthwash to Reduce Shedding of Infectious SARS-CoV-2: A Double-Blind Randomized Clinical Trial

A. Alemany et al.

Summary: This study evaluated the impact of mouthwashes containing cetylpyridinium chloride (CPC) on the transmission of SARS-CoV-2. The results showed that the use of 0.07% CPC mouthwash in nonhospitalized patients significantly increased the levels of viral nucleocapsid protein in saliva, indicating enhanced disruption of viral particles.

JOURNAL OF DENTAL RESEARCH (2022)

添加到收藏夹

Article Virology

Mouthrinses against SARS-CoV-2-High antiviral effectivity by membrane disruption in vitro translates to mild effects in a randomized placebo-controlled clinical trial

Toni Luise Meister et al.

Summary: The emergence of SARS-CoV-2 poses an unprecedented threat to humans, requiring rapid and effective intervention measures. Antiseptic agents, such as benzalkoniumchloride, have shown promise in inactivating SARS-CoV-2 in vitro, but their clinical application has only resulted in a mild reduction of viral loads in the oral cavity.

VIRUS RESEARCH (2022)

添加到收藏夹

Review Environmental Sciences

Oral Antiseptics against SARS-CoV-2: A Literature Review

Cristian Gabriel Guerrero Bernal et al.

Summary: Dentists are at the highest risk of exposure to COVID-19 and have implemented additional disinfection strategies for their protection. Oral antiseptics, although not proven to prevent the transmission of SARS-CoV-2, have been recommended as control measures by various health institutions worldwide.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

添加到收藏夹

Article Immunology

Effect of oral antiseptics in reducing SARS-CoV-2 infectivity: evidence from a randomized double-blind clinical trial

Alvaro Sanchez Barrueco et al.

Summary: Although in vitro studies have shown that some oral antiseptics have virucidal activity against SARS-CoV-2, this study found that these mouthwashes did not affect the viral load in saliva. Only cetylpyridinium chloride (CPC) significantly reduced viral infectivity, but the effect was only observed one hour after mouthwash. The use of mouthwashes does not immediately reduce viral transmission and may create a false sense of security.

EMERGING MICROBES & INFECTIONS (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Effect of oral antiseptics on the viral load of SARS-CoV-2: A randomized controlled trial

Sema Nur Sevinc Gul et al.

Summary: This study found that gargling with hypochlorous acid and povidone-iodine solutions did not significantly reduce the oral viral load of SARS-CoV-2. Therefore, these findings suggest that antiseptics have no role in controlling the transmission of SARS-CoV-2 through aerosols generated during dental procedures or in general.

DENTAL AND MEDICAL PROBLEMS (2022)

添加到收藏夹

Article

Efficacy of Hexetidine, Thymol and Hydrogen Peroxide-Containing Oral Antiseptics in Reducing Sars-Cov-2 Virus in the Oral Cavity: A Pilot Study

Ogun

West African Journal of Medicine (2022)

添加到收藏夹

Review Environmental Sciences

Triclosan and triclocarban as potential risk factors of colitis and colon cancer: Roles of gut microbiota involved

Katherine Z. Sanidad et al.

Summary: In recent years, there has been a significant increase in the occurrence of inflammatory bowel disease (IBD), a chronic inflammatory disease of the intestines. Exposure to the chemicals triclosan (TCS) and triclocarban (TCC) may contribute to the development of IBD and associated diseases, as studies have shown that exposure to these chemicals increases the severity of colitis and exacerbates colon tumorigenesis in mice. The presence of gut microbiota is necessary for the toxic effects of these compounds.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

USE OF MOUTHWASH AND DENTIFRICE CONTAINING AN ANTIMICROBIAL PHTHALOCYANINE DERIVATIVE FOR THE REDUCTION OF CLINICAL SYMPTOMS OF COVID-19: A RANDOMIZED TRIPLE-BLIND CLINICAL TRIAL

Marcelo Lupion Poleti et al.

Summary: This clinical trial found that mouthwash and dentifrice can have a positive impact on reducing clinical symptoms in patients with COVID-19.

JOURNAL OF EVIDENCE-BASED DENTAL PRACTICE (2022)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Evaluation of current evidence on the use of oral antiseptics against SARS-CoV-2: A narrative review

Victor Chumpitaz-Cerrate et al.

Summary: This review aimed to assess the current evidence on the use of oral antiseptics against SARS-CoV-2 and found that they may have potential benefits in reducing viral load. However, the certainty of the evidence is very low due to methodological limitations. Therefore, more rigorous clinical studies are needed for evidence-based decision-making.

JOURNAL OF INTERNATIONAL SOCIETY OF PREVENTIVE AND COMMUNITY DENTISTRY (2022)

添加到收藏夹

Article Medicine, General & Internal

The short-term effect of different chlorhexidine forms versus povidone iodine mouth rinse in minimizing the oral SARS-CoV-2 viral load: An open label randomized controlled clinical trial study

Zuhair S. Natto et al.

Summary: This study assessed the short-term efficacy of over-the-counter mouth rinses and lozenges in reducing the salivary viral load of SARS-CoV-2 in COVID-19 patients. The results indicated that povidone iodine mouth rinse showed a potential influence on reducing the viral load in the short term, but longer-term studies are needed.

MEDICINE (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

Impact of Steam Inhalation, Saline Gargling, and Povidone-Iodine Gargling on Clinical Outcome of COVID-19 Patients in Bengaluru, Karnataka: A Randomized Control Trial

Vani H. Chalageri et al.

Summary: A randomized controlled trial conducted in Bangalore from September 2020 to February 2021 aimed to assess the effect of steam inhalation, saline gargling, and povidone-iodine gargling among COVID-19-positive patients. The results showed that povidone-iodine gargling was effective in achieving early test negativity, while saline gargling was effective in early clinical recovery.

INDIAN JOURNAL OF COMMUNITY MEDICINE (2022)

添加到收藏夹

Article Surgery

Virucidal effect of povidone iodine on COVID-19 in the nasopharynx: an open-label randomized clinical trial

Mostafa Kamal Arefin et al.

Summary: Povidone-iodine (PVP-I) has shown promising virucidal properties against SARS-CoV-2 in vitro, making it a potential option for preventing COVID-19, although more research is needed to confirm its efficacy in human subjects.

INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY (2022)

添加到收藏夹

Article Otorhinolaryngology

Efficacy of Povidone-Iodine Nasal and Oral Antiseptic Preparations Against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)

Jesse S. Pelletier et al.

Summary: The study demonstrated that povidone iodine nasal and oral antiseptic formulations were effective at completely inactivating SARS-CoV-2 virus within 60 seconds, potentially reducing the transmission of COVID-19.

ENT-EAR NOSE & THROAT JOURNAL (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Hydrogen peroxide as an auxiliary treatment for COVID-19 in Brazil: a randomized double-blind clinical trial

Marielle Bazzo Di Domenico et al.

Summary: This study found that H2O2 as mouthwash and nasal spray was not effective in relieving symptoms of COVID-19 patients, and was associated with certain adverse effects.

EPIDEMIOLOGY AND HEALTH (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Salivary SARS-CoV-2 load reduction with mouthwash use: A randomized pilot clinical trial

Fernanda de Paula Eduardo et al.

Summary: The study showed that mouthwash containing cetylpyridinium chloride plus zinc lactate and chlorhexidine gluconate significantly reduced the SARS-CoV-2 viral load in saliva up to 60 minutes after rinsing, while hydrogen peroxide mouthwash resulted in a significant reduction up to 30 minutes after rinsing.

HELIYON (2021)

添加到收藏夹

Article Virology

Lowering the transmission and spread of human coronavirus

Craig Meyers et al.

Summary: The emergence of the COVID-19 pandemic has caused unprecedented healthcare, social, and economic crises. While wearing masks and practicing social distancing can help reduce transmission, additional strategies are needed to further mitigate the risk.

JOURNAL OF MEDICAL VIROLOGY (2021)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Virucidal activity of oral care products against SARS-CoV-2 in vitro

Akihiko Komine et al.

Summary: The study found that oral care products containing CPC or delmopinol hydrochloride can inactivate the SARS-CoV-2 virus in vitro, suggesting that these products may reduce viral load in the mouth.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY (2021)

添加到收藏夹

Meeting Abstract Critical Care Medicine

ORAL GARGLE OF ETHANOL-BASED MOUTHWASH SOLUTION AND ITS EFFECTS ON ADULT PATIENTS WITH MILD COVID-19 INFECTION: AN OPEN LABEL-RANDOMIZED CONTROLLED TRIAL

Lawrence Cyril Vitug et al.

CHEST (2021)

添加到收藏夹

Article Infectious Diseases

Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: randomized control trial in Singapore

Chaminda J. Seneviratne et al.

Summary: The study found that using cetylpyridinium chloride and povidone-iodine mouth rinses can effectively reduce the salivary SARS-CoV-2 viral load in COVID-19 patients. Especially in high-risk procedures such as dental treatment, using these mouth rinses may help reduce the risk of virus transmission.

INFECTION (2021)

添加到收藏夹

Letter Medicine, Research & Experimental

Virucidal effect of povidone iodine on COVID-19 in the nasopharynx: A structured summary of a study protocol for an open-label randomized clinical trial

Mohammad Jahid Hasan et al.

Summary: The study aims to assess the virucidal efficacy of povidone iodine (PVP-I) on COVID-19 virus in the nasopharynx. It is a single-center, open-label randomized clinical trial with a 7-arm parallel-group design.

TRIALS (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Virucidal effect of povidone-iodine against SARS-CoV-2 in vitro

Ying Wang et al.

Summary: The study demonstrated that PVP-I at concentrations >0.5 mg/ml in contact with SARS-CoV-2 for 30 s, 1 min, 2 min, and 5 min showed up to 99% viral inhibition. A contact time of 1 min with PVP-I exhibited a virucidal effect, and there was no cytotoxic effects on cells at concentrations tested (0.125-1 mg/ml).

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2021)

添加到收藏夹

Article Health Care Sciences & Services

Characteristics of First Cases of Coronavirus Disease 2019 and the Effort to Prevent the Early Spread of COVID-19 in Saudi Arabia

Zuhair S. Natto et al.

Summary: The early cases of COVID-19 in Saudi Arabia showed an increasing trend, with travel being the main source of infection. Males and Saudi nationals were the most affected groups, with Mecca having the highest concentration of cases. The Saudi government implemented various measures to minimize infection spread, as the trend of increasing cases is expected to continue.

RISK MANAGEMENT AND HEALTHCARE POLICY (2021)

添加到收藏夹

Article Medicine, General & Internal

SARS-CoV-2 Transmission From People Without COVID-19 Symptoms

Michael A. Johansson et al.

Summary: The study suggests that more than half of COVID-19 transmission may come from asymptomatic individuals, highlighting the importance of measures beyond identifying and isolating symptomatic cases in controlling the spread of the virus.

JAMA NETWORK OPEN (2021)

添加到收藏夹

Article Physiology

Carrageenan-containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures

Desiree Schuetz et al.

Summary: The study found that carrageenan in certain nasal and mouth sprays can effectively inhibit SARS-CoV-2 infection, reducing the risk of viral spread.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2021)

添加到收藏夹

Article Microbiology

Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients

David M. Goldfarb et al.

Summary: This study evaluated the performance, stability, and user acceptability of different self-collected sample types for detecting SARS-CoV-2. Saline mouth rinse/gargle samples showed excellent sensitivity and stability, as well as the highest acceptability scores, making them a promising option for outpatient self-collection in adults and school-aged children.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Comparison of the in-vitro efficacy of different mouthwash solutions targeting SARS-CoV-2 based on the European Standard EN 14476

K. Steinhauer et al.

Summary: The outbreak of the SARS-CoV-2 pandemic has led to a global health emergency alert, requiring urgent effective preventive measures. Recent research has emphasized the relevance of aerosols in the spread of SARS-CoV-2. An investigation of commercially available antiseptic mouthwashes based on OCT has shown effectiveness against SARS-CoV-2, making it a potential candidate for future clinical studies on prevention of transmission.

JOURNAL OF HOSPITAL INFECTION (2021)

添加到收藏夹

Letter Otorhinolaryngology

Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial

Jeremy Guenezan et al.

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY (2021)

添加到收藏夹

Article Microbiology

Inactivation of SARS-CoV-2 through Treatment with the Mouth Rinsing Solutions ViruProX(R) and BacterX(R) Pro

Julia Koch-Heier et al.

Summary: Preprocedural mouth rinses with ViruProX(R) or BacterX(R) pro containing CPC and H2O2 or CHX, CPC, and F- successfully inactivated infectious SARS-CoV-2 particles within 30 seconds. While a combination of CPC and CHX as well as CPC alone led to a significant reduction of infectious viral particles, H2O2 and CHX alone had no virucidal effect against SARS-CoV-2.

MICROORGANISMS (2021)

添加到收藏夹

Article Microbiology

Differential Effects of Antiseptic Mouth Rinses on SARS-CoV-2 Infectivity In Vitro

Chuan Xu et al.

Summary: The study found that mouth rinses like Colgate Peroxyl and povidone-iodine can significantly reduce the infectivity of SARS-CoV-2 virus. The antiviral activities of these rinses were linked to cellular damage, with prolonged effects enhancing their efficacy.

PATHOGENS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Beneficial effects of a mouthwash containing an antiviral phthalocyanine derivative on the length of hospital stay for COVID-19: randomised trial

Paulo Sergio da Silva Santos et al.

Summary: The study found that using a mouthwash containing a compound with antiviral effects against SARS-CoV-2 may reduce symptoms and spread of infection in patients, helping to shorten hospital stay.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2

Maria D. Ferrer et al.

Summary: This study tested the efficacy of mouthwashes in reducing salivary viral load in COVID-19 patients, but found no significant decrease in viral load. Further studies on viral infectivity post-mouthwash use are deemed necessary.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Review Environmental Sciences

Recommendations for Safe Dental Care: A Systematic Review of Clinical Practice Guidelines in the First Year of the COVID-19 Pandemic

Naira Figueiredo Deana et al.

Summary: Clinical practice guidelines recommend specific measures to reduce the risk of COVID-19 transmission in dental care, such as using rubber dam, high-volume evacuator, mouthwash, four-handed work, and mechanical barriers, while avoiding the use of aerosol-generating equipment whenever possible.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

添加到收藏夹

Article Infectious Diseases

Effect of Ammonium Chloride in addition to standard of care in outpatients and hospitalized COVID-19 patients: A randomized clinical trial

Zeinab Siami et al.

Summary: In this study, the addition of Ammonium Chloride to standard care for COVID-19 patients showed significant benefits, including a shorter recovery time and lower viral burden, suggesting its potential as a treatment option for the disease.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Infectious Diseases

Positive impact of oral hydroxychloroquine and povidone-iodine throat spray for COVID-19 prophylaxis: An open-label randomized trial

Raymond Chee Seong Seet et al.

Summary: The study found that chemoprophylaxis with either oral hydroxychloroquine or povidone-iodine throat spray was superior to oral vitamin C in reducing SARS-CoV-2 infection in young and healthy men. Participants receiving zinc/vitamin C combination had the highest rate of interruptions due to side effects.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

添加到收藏夹

Letter Infectious Diseases

Comparison of saliva and nasopharyngeal swab SARS-CoV-2 RT-qPCR testing in a community setting

Monique Torres et al.

JOURNAL OF INFECTION (2021)

添加到收藏夹

Article Virology

Use of chlorhexidine to eradicate oropharyngeal SARS-CoV-2 in COVID-19 patients

Y. Hanna Huang et al.

Summary: Chlorhexidine as an oral antimicrobial agent may significantly reduce SARS-CoV-2 presence in the oral and oropharyngeal cavities of hospitalized COVID-19 patients, showing a potential role in disease spread prevention.

JOURNAL OF MEDICAL VIROLOGY (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

SARS-CoV-2: Overview and Its Impact on Oral Health

Miriam Ting et al.

Summary: The spread of SARS-CoV-2 and its variants causing COVID-19 is rapid and highly contagious. Factors like periodontal health, good oral hygiene, and access to dental care may play a role in combating SARS-CoV-2 infection. Maintaining overall health, good oral hygiene, and quitting smoking may be beneficial in preventing and managing COVID-19 infections.

BIOMEDICINES (2021)

添加到收藏夹

Article Health Care Sciences & Services

Infection Control Practices at the Dental Clinics in Jeddah, Saudi Arabia

Zuhair S. Natto et al.

Summary: The study revealed that most dental clinics in Jeddah follow infection control measures and implement strict protective requirements during the COVID-19 period. The incidence of COVID-19 was found to be higher among dental staff, indicating a need for further strengthening infection control practices.

JOURNAL OF MULTIDISCIPLINARY HEALTHCARE (2021)

添加到收藏夹

Letter Medicine, Research & Experimental

Reconvalescent plasma/camostat mesylate in early SARS-CoV-2 Q-PCR positive high-risk individuals (RES-Q-HR): a structured summary of a study protocol for a randomized controlled trial

Verena Keitel et al.

TRIALS (2021)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

IN VIVO EVALUATION OF THE VIRUCIDAL EFFICACY OF CHLORHEXIDINE AND POVIDONE-IODINE MOUTHWASHES AGAINST SALIVARY SARS-COV-2. A RANDOMIZED-CONTROLLED CLINICAL TRIAL

Rola Elzein et al.

Summary: The study aimed to evaluate the effectiveness of two preprocedural mouthrinses in reducing salivary SARS-CoV-2 viral load and compared the results to a control group. The results showed that 0.2% Chlorhexidine and 1% Povidone-iodine oral solutions are effective in reducing salivary SARS-CoV-2 in dental treatments, suggesting their use as a preventive strategy during dental practice.

JOURNAL OF EVIDENCE-BASED DENTAL PRACTICE (2021)

添加到收藏夹

Article Otorhinolaryngology

Mouthrinses against SARS-CoV-2: anti-inflammatory effectivity and a clinical pilot study

Matthias Schurmann et al.

Summary: The study aimed to confirm the effectiveness of over the counter mouthwash solutions in reducing viral load in the saliva of COVID-19 patients and investigating the potential immune modulation effects. The results showed that the mouth rinsing solution reduced viral load by about 90% in most patients and the effects lasted for approximately 6 hours. Further research is needed to explore the potential benefits of using zinc and dexpanthenol in mouthwash formulations for improving patients' health.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY (2021)

添加到收藏夹

Article Infectious Diseases

The role of mouthwash sampling in SARS-CoV-2 diagnosis

Asaf Biber et al.

Summary: The study explored mouthwash (MW) as an alternative diagnostic method for COVID-19, comparing its effectiveness with oro-nasopharyngeal (ONP) swabs. Results showed that MW targeting the N gene was comparable to ONP swabs targeting the E and R genes, suggesting that MW with normal saline can effectively detect COVID-19 patients.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro

J. Munoz-Basagoiti et al.

Summary: Cetylpyridinium chloride (CPC) in oral mouthwashes reduces SARS-CoV-2 infectivity by disrupting the integrity of the viral envelope and inhibiting the fusion with target cells. This antiviral activity is effective against different SARS-CoV-2 variants, making CPC-containing mouth rinses a cost-effective measure to reduce viral transmission from infected individuals.

JOURNAL OF DENTAL RESEARCH (2021)

添加到收藏夹

Letter Infectious Diseases

Self-collected mid-nasal swabs and saliva specimens, compared with nasopharyngeal swabs, for SARS-CoV-2 detection in mild COVID-19 patients

Andrea Alemany et al.

JOURNAL OF INFECTION (2021)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Estimating salivary carriage of severe acute respiratory syndrome coronavirus 2 in nonsymptomatic people and efficacy of mouthrinse in reducing viral load A randomized controlled trial

PremPrashant Chaudhary et al.

Summary: The study found that 23%, 28%, and 60% of asymptomatic, presymptomatic, and postsymptomatic individuals respectively carry SARS-CoV-2 in their saliva. Mouthrinses can significantly reduce viral load in less than an hour, especially with lower initial viral loads.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION (2021)

添加到收藏夹

Review Public, Environmental & Occupational Health

In vitro studies evaluating the efficacy of mouth rinses on Sars-Cov-2: A systematic review

Jyothi Tadakamadla et al.

Summary: This systematic review evaluated the efficacy of mouth rinses on SARS-CoV-2 from in vitro studies, finding Povidone Iodine to be the most effective. Chlorhexidine's effectiveness was inconclusive, while hydrogen peroxide was less effective. Other active ingredients also showed promising results in reducing viral load.

JOURNAL OF INFECTION AND PUBLIC HEALTH (2021)

添加到收藏夹

Article Medicine, General & Internal

Characterizing long COVID in an international cohort: 7 months of symptoms and their impact

Hannah E. Davis et al.

Summary: Patients with Long COVID report prolonged, multisystem involvement and significant disability. By seven months, many patients have not yet recovered (mainly from systemic and neurological/cognitive symptoms), have not returned to previous levels of work, and continue to experience significant symptom burden.

ECLINICALMEDICINE (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Effectiveness of hydrogen peroxide as auxiliary treatment for hospitalized COVID-19 patients in Brazil: preliminary results of a randomized double-blind clinical trial

Marielle Bazzo Di Domenico et al.

Summary: The study found that using H2O2 as a mouthwash and nasal spray in COVID-19 patients is safe, but there is insufficient evidence to prove its effectiveness as an auxiliary treatment for hospitalized patients.

EPIDEMIOLOGY AND HEALTH (2021)

添加到收藏夹

Article Immunology

Consistent Detection of 2019 Novel Coronavirus in Saliva

Kelvin Kai-Wang To et al.

CLINICAL INFECTIOUS DISEASES (2020)

添加到收藏夹

Letter Dentistry, Oral Surgery & Medicine

Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis

Robinson Sabino-Silva et al.

CLINICAL ORAL INVESTIGATIONS (2020)

添加到收藏夹

Review Public, Environmental & Occupational Health

Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents

G. Kampf et al.

JOURNAL OF HOSPITAL INFECTION (2020)

添加到收藏夹

Letter Medicine, General & Internal

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

Lirong Zou et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Transmission routes of 2019-nCoV and controls in dental practice

Xian Peng et al.

INTERNATIONAL JOURNAL OF ORAL SCIENCE (2020)

添加到收藏夹

Article Microbiology

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

Alexander E. Gorbalenya et al.

NATURE MICROBIOLOGY (2020)

添加到收藏夹

Letter Dentistry, Oral Surgery & Medicine

Povidone iodine

S. J. Challacombe et al.

BRITISH DENTAL JOURNAL (2020)

添加到收藏夹

Letter Immunology

Gargle Lavage as a Safe and Sensitive Alternative to Swab Samples to Diagnose COVID-19: A Case Report in Japan

Makoto Saito et al.

CLINICAL INFECTIOUS DISEASES (2020)

添加到收藏夹

Article Otorhinolaryngology

COVID-19 pandemic: Effects and evidence-based recommendations for otolaryngology and head and neck surgery practice

Luiz P. Kowalski et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2020)

添加到收藏夹

Letter Dentistry, Oral Surgery & Medicine

Salivary Glands: Potential Reservoirs for COVID-19 Asymptomatic Infection

J. Xu et al.

JOURNAL OF DENTAL RESEARCH (2020)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine

L. Meng et al.

JOURNAL OF DENTAL RESEARCH (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Virological assessment of hospitalized patients with COVID-2019

Roman Woelfel et al.

NATURE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Temporal dynamics in viral shedding and transmissibility of COVID-19

Xi He et al.

NATURE MEDICINE (2020)

添加到收藏夹

Letter Medicine, General & Internal

Droplets and Aerosols in the Transmission of SARS-CoV-2

Matthew Meselson

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Interventions to Reduce Aerosolized Microbes in Dental Practice: A Systematic Review with Network Meta-analysis of Randomized Controlled Trials

D. Koletsi et al.

JOURNAL OF DENTAL RESEARCH (2020)

添加到收藏夹

Article Infectious Diseases

Povidone-Iodine Demonstrates Rapid In Vitro Virucidal Activity Against SARS-CoV-2, The Virus Causing COVID-19 Disease

Danielle E. Anderson et al.

INFECTIOUS DISEASES AND THERAPY (2020)

添加到收藏夹

Article Immunology

Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2

Toni Luise Meister et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

添加到收藏夹

Article Otorhinolaryngology

Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic

Mubarak Muhamed Khan et al.

AMERICAN JOURNAL OF OTOLARYNGOLOGY (2020)

添加到收藏夹

Editorial Material Medicine, General & Internal

SARS-CoV-2 Vaccine Acceptance: We May Need to Choose Our Battles

Alison M. Buttenheim

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Editorial Material Infectious Diseases

Understanding COVID-19: what does viral RNA load really mean?

Gavin M. Joynt et al.

LANCET INFECTIOUS DISEASES (2020)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

A prospective clinical pilot study on the effects of a hydrogen peroxide mouthrinse on the intraoral viral load of SARS-CoV-2

Maximilian J. Gottsauner et al.

CLINICAL ORAL INVESTIGATIONS (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

Ching-Lin Hsieh et al.

SCIENCE (2020)

添加到收藏夹

Letter Medicine, Research & Experimental

Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, Canada

Julie K. Wright et al.

TRIALS (2020)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Rapid In-Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Using Povidone-Iodine Oral Antiseptic Rinse

Avinash S. Bidra et al.

JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY (2020)

添加到收藏夹

Letter Medicine, General & Internal

Thrombo-prophylaxis prevents thrombotic events in home-managed COVID patients A registry study

Gianni Belcaro et al.

MINERVA MEDICA (2020)

添加到收藏夹

Letter Medicine, General & Internal

Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2

Anne L. Wyllie et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Article Medicine, Research & Experimental

A quadruple blind, randomised controlled trial of gargling agents in reducing intraoral viral load among hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial

Farhan Raza Khan et al.

TRIALS (2020)

添加到收藏夹

Letter Anesthesiology

Preanesthetic Povidone-Iodine gargles for patients with COVID-19

Varun Suresh et al.

JOURNAL OF CLINICAL ANESTHESIA (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Underdetection of cases of COVID-19 in France threatens epidemic control

Giulia Pullano et al.

NATURE (2020)

添加到收藏夹

Article Medicine, General & Internal

Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva

Jin Gu Yoon et al.

JOURNAL OF KOREAN MEDICAL SCIENCE (2020)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Effects of oral care on prolonged viral shedding in coronavirus disease 2019 (COVID-19)

Yoko Warabi et al.

SPECIAL CARE IN DENTISTRY (2020)

添加到收藏夹

Review Cell Biology

Potential Role of Oral Rinses Targeting the Viral Lipid Envelope in SARS-CoV-2 Infection

Valerie B. O'Donnell et al.

FUNCTION (2020)

添加到收藏夹

Review Microbiology

Resistance Toward Chlorhexidine in Oral Bacteria - Is There Cause for Concern?

Fabian Cieplik et al.

FRONTIERS IN MICROBIOLOGY (2019)

添加到收藏夹

Article Medicine, General & Internal

RoB 2: a revised tool for assessing risk of bias in randomised trials

Jonathan A. C. Sterne et al.

BMJ-BRITISH MEDICAL JOURNAL (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Adverse events associated with home use of mouthrinses: a systematic review

Gianluca M. Tartaglia et al.

THERAPEUTIC ADVANCES IN DRUG SAFETY (2019)

添加到收藏夹

Review Infectious Diseases

Infectious Disease Management and Control with Povidone Iodine

Maren Eggers

INFECTIOUS DISEASES AND THERAPY (2019)

添加到收藏夹

Review Infectious Diseases

Biocidal Agents Used for Disinfection Can Enhance Antibiotic Resistance in Gram-Negative Species

Guenter Kampf

ANTIBIOTICS-BASEL (2018)

添加到收藏夹

Article Infectious Diseases

In Vitro Bactericidal and Virucidal Efficacy of Povidone-Iodine Gargle/Mouthwash Against Respiratory and Oral Tract Pathogens

Maren Eggers et al.

INFECTIOUS DISEASES AND THERAPY (2018)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

The antiplaque and bleeding control effects of a cetylpyridinium chloride and tranexamic acid mouth rinse in patients with gingivitis

Ji-Eun Lee et al.

JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE (2017)

添加到收藏夹

Article Infectious Diseases

Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections

Pranab K. Mukherjee et al.

BMC INFECTIOUS DISEASES (2017)

添加到收藏夹

Review Public, Environmental & Occupational Health

Acquired resistance to chlorhexidine - is it time to establish an 'antiseptic stewardship' initiative?

G. Kampf

JOURNAL OF HOSPITAL INFECTION (2016)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

The effect of chlorhexidine dentifrice or gel versus chlorhexidine mouthwash on plaque, gingivitis, bleeding and tooth discoloration: a systematic review

S. C. Supranoto et al.

INTERNATIONAL JOURNAL OF DENTAL HYGIENE (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Chlorhexidine Substantivity on Salivary Flora and Plaque-Like Biofilm: An In Situ Model

Lucia Garcia-Caballero et al.

PLOS ONE (2013)

添加到收藏夹

Review Infectious Diseases

Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action

Ezra Linley et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2012)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Retention of Antimicrobial Activity in Plaque and Saliva following Mouthrinse Use in vivo

M. P. T. Otten et al.

CARIES RESEARCH (2010)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

In vivo substantivity of 0.12% and 0.2% chlorhexidine mouthrinses on salivary bacteria

Maria Consuelo Cousido et al.

CLINICAL ORAL INVESTIGATIONS (2010)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

The efficacy of 0.12% chlorhexidine mouthrinse compared with 0.2% on plaque accumulation and periodontal parameters: a systematic review

C. E. Berchier et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2010)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

In vivo bactericidal effect of 0.2% chlorhexidine but not 0.12% on salivary obligate anaerobes

I. Tomas et al.

ARCHIVES OF ORAL BIOLOGY (2008)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Adverse events associated with chlorhexidine use - Results from the department of veterans affairs dental diabetes study

Linda C. McCoy et al.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION (2008)

添加到收藏夹

Article Medical Laboratory Technology

Characterization of RNA in saliva

Noh Jin Park et al.

CLINICAL CHEMISTRY (2006)

添加到收藏夹

Article Dermatology

Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions and chemical reagents

H Kariwa et al.

DERMATOLOGY (2006)

添加到收藏夹

Review Infectious Diseases

Biocide use and antibiotic resistance: the relevance of laboratory findings to clinical and environmental situations

AD Russell

LANCET INFECTIOUS DISEASES (2003)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Saliva in health and disease: an appraisal and update

LM Sreebny

INTERNATIONAL DENTAL JOURNAL (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.