4.7 Article

Modifications of the PI3K/Akt/mTOR axis during FeHV-1 infection in permissive cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

Non-Structural Protein 3 of Duck Tembusu Virus Induces Autophagy via the ERK and PI3K-AKT-mTOR Signaling Pathways

Jun Zhao et al.

Summary: Despite the economic losses caused by duck Tembusu virus (DTMUV) to the poultry industry, the specific relationships between DTMUV and cellular autophagy are largely unknown. This study investigated the interactions between autophagy and DTMUV and found that DTMUV increased autophagy, which in turn facilitated viral replication. Non-structural protein 3 (NS3) was identified as the main protein inducing autophagy, and this induction was mediated by the ERK2, PI3K/AKT, and mTOR signaling pathways. NS3-induced autophagy promoted DTMUV replication.

FRONTIERS IN IMMUNOLOGY (2022)

Article Veterinary Sciences

Porcine parvovirus triggers autophagy through the AMPK/Raptor/mTOR pathway to promote viral replication in porcine placental trophoblasts

Xiujuan Zhang et al.

Summary: Porcine parvovirus infection induces autophagy to promote viral replication by inhibiting the activation of mTORC1 through the AMPK/Raptor pathway.

VETERINARY RESEARCH (2022)

Review Immunology

Herpes Simplex Virus Cell Entry Mechanisms: An Update

Krishnaraju Madavaraju et al.

Summary: Herpes simplex virus has a wide host range and can cause severe infections in humans. Its surface glycoproteins play a crucial role in binding to host cell receptors and facilitating the entry process. Understanding the mechanisms of viral entry is essential for developing antiviral strategies against HSV.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Article Immunology

Dengue Virus Dysregulates Master Transcription Factors and PI3K/AKT/mTOR Signaling Pathway in Megakaryocytes

Anismrita Lahon et al.

Summary: This study investigates the impact of DENV infection on megakaryocyte development and maturation, revealing a crucial role of the PI3K/AKT/mTOR pathway in this process. The findings suggest that DENV impairs this pathway, affecting the development and maturation of megakaryocytes.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Article Pharmacology & Pharmacy

HCMV modulation of cellular PI3K/AKT/mTOR signaling: New opportunities for therapeutic intervention?

Aaron M. Altman et al.

ANTIVIRAL RESEARCH (2019)

Article Oncology

Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy

Serena Montagnaro et al.

CANCER BIOLOGY & THERAPY (2019)

Article Biotechnology & Applied Microbiology

Autophagy activated by duck enteritis virus infection positively affects its replication

Hai-Chang Yin et al.

JOURNAL OF GENERAL VIROLOGY (2017)

Article Pathology

Feline Herpesvirus Pneumonia: Investigations Into the Pathogenesis

Josep Maria Monne Rodriguez et al.

VETERINARY PATHOLOGY (2017)

Article Biochemistry & Molecular Biology

Feline Herpesvirus-1 Down-Regulates MHC Class I Expression in an Homologous Cell System

S. Montagnaro et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2009)

Review Microbiology

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway

Nicholas J. Buchkovich et al.

NATURE REVIEWS MICROBIOLOGY (2008)

Article Microbiology

EBV latent membrane protein 1 activates Akt, NFκB, and Stat3 in B cell lymphomas

Kathy H. Y. Shair et al.

PLOS PATHOGENS (2007)