期刊
DIAGNOSTICS
卷 13, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/diagnostics13101674
关键词
dementia and related disorders; neurodegenerative disorders; neuroimaging; nuclear medicine; Parkinson disease and related disorders
Extensive research on crossed cerebellar diaschisis (CCD) in neurodegenerative disorders is lacking. While PET is commonly used to detect CCD, advanced MRI techniques have also emerged for this purpose. This study aimed to evaluate whether PET provides additional value compared to MRI or advanced MRI techniques in detecting CCD. Eight articles involving 1246 participants were included in this review, with six using PET imaging and two using MRI and hybrid imaging. PET studies showed decreased cerebral metabolism in various cortices, while MRI studies showed decreased cerebellar volumes. The study concluded that PET is a common and sensitive technique for detecting CCD in neurodegenerative diseases, while MRI is better for measuring brain volume.
There has not been extensive research into crossed cerebellar diaschisis (CCD) in neurodegenerative disorders. CCD is frequently detected using positron emission tomography (PET). However, advanced MRI techniques have come forth for the detection of CCD. The correct diagnosis of CCD is crucial for the care of neurological patients and those with neurodegenerative conditions. The purpose of this study is to determine whether PET can offer extra value over MRI or an advanced technique in MRI for detecting CCD in neurological conditions. We searched three main electronic databases from 1980 until the present and included only English and peer-reviewed journal articles. Eight articles involving 1246 participants met the inclusion criteria, six of which used PET imaging while the other two used MRI and hybrid imaging. The findings in PET studies showed decreased cerebral metabolism in the frontal, parietal, temporal, and occipital cortices, as on the opposite side of the cerebellar cortex. However, the findings in MRI studies showed decreased cerebellar volumes. This study concludes that PET is a common, accurate, and sensitive technique for detecting both crossed cerebellar and uncrossed basal ganglia as well as thalamic diaschisis in neurodegenerative diseases, while MRI is better for measuring brain volume. This study suggests that PET has a higher diagnostic value for diagnosing CCD compared to MRI, and that PET is a more valuable technique for predicting CCD.
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