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Sexually Transmitted Diseases-An Update and Overview of Current Research

DIAGNOSTICS (2023)

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Article Medicine, General & Internal

Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections

Anne F. Luetkemeyer et al.

Summary: In this study, it was found that doxycycline postexposure prophylaxis significantly reduced the incidence of sexually transmitted infections (STIs) among MSM and transgender women. The use of doxycycline was shown to be effective in preventing STIs in this population.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

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Review Medicine, General & Internal

Diagnosis and Treatment of Sexually Transmitted Infections A Review

Susan Tuddenham et al.

Summary: Approximately 1 in 5 adults in the US had a sexually transmitted infection (STI) in 2018. Rates of gonorrhea, chlamydia, and syphilis in the US have increased, while rates of HSV-1 and HSV-2 have declined. Effective treatments are available for most STIs, but antimicrobial resistance limits oral therapies for gonorrhea and Mycoplasma genitalium, and no cure is available for genital herpes.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Dermatology

2021 European guideline on the management of Mycoplasma genitalium infections

J. S. Jensen et al.

Summary: Mycoplasma genitalium infection is responsible for a significant number of cases of non-chlamydial non-gonococcal urethritis in men and is associated with cervicitis and pelvic inflammatory disease in women. Transmission occurs through direct mucosal contact. Asymptomatic infections are common. Diagnosis is achieved through nucleic acid amplification testing, including investigation for macrolide resistance mutations.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2022)

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Article Immunology

Centers for Disease Control and Prevention's Sexually Transmitted Diseases Infection Guidelines

Kimberly A. Workowski et al.

CLINICAL INFECTIOUS DISEASES (2022)

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Review Medicine, General & Internal

Vaginal Microbiome in Reproductive Medicine

Veronika Guenther et al.

Summary: The human microbiome, particularly the vaginal microbiome, has gained importance in reproductive medicine due to its potential influence on infertility and implantation failure. Non-Lactobacillus-dominated microbiomes have been associated with dysbiosis and may negatively impact reproductive outcomes. Screening the microbiome and administering antibiotic and/or probiotic treatment could improve pregnancy outcomes.

DIAGNOSTICS (2022)

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Article Public, Environmental & Occupational Health

Sexually Transmitted Infections Treatment Guidelines, 2021

Kimberly A. Workowski et al.

MMWR Recommendations and Reports (2021)

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Article Immunology

Pathogenesis and virulence of herpes simplex virus

Shuyong Zhu et al.

Summary: HSV-1 and HSV-2 are two of the most prevalent human viruses worldwide, causing a variety of diseases. Immune responses play a key role in controlling HSV, but the virus has developed mechanisms to evade them. The severity of disease upon HSV infection varies among individuals, partly due to genetic polymorphisms. HSV has lytic and latent replication cycles, with the latter leading to disease.

VIRULENCE (2021)

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Review Public, Environmental & Occupational Health

Chlamydia trachomatis Screening and Treatment in Pregnancy to Reduce Adverse Pregnancy and Neonatal Outcomes: A Review

Kristina N. Adachi et al.

Summary: This review examines the potential benefits of antenatal screening and treatment of Chlamydia trachomatis in preventing adverse pregnancy and infant outcomes. The majority of studies analyzed in the review provide some degree of support for the effectiveness of these interventions in decreasing adverse outcomes. Additional research from low and middle-income settings is needed to further validate these findings.

FRONTIERS IN PUBLIC HEALTH (2021)

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Article Obstetrics & Gynecology

Pelvic inflammatory disease

Anna Westermann et al.

Summary: Pelvic inflammatory disease (PID) is a group of inflammatory diseases affecting the uterus and adnexa, primarily caused by ascending infections from the vagina and cervix. The pathogens mainly include Chlamydia trachomatis and Neisseria gonorrhoeae. Symptoms vary depending on the infected compartment, with complications such as tubo-ovarian abscess and perihepatitis.

GYNAKOLOGE (2021)

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Review Infectious Diseases

Pregnancy and fertility-related adverse outcomes associated withChlamydia trachomatisinfection: a global systematic review and meta-analysis

Weiming Tang et al.

SEXUALLY TRANSMITTED INFECTIONS (2020)

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Review Oncology

Biological and clinical aspects of HPV-related cancers

Klaudia Anna Szymonowicz et al.

CANCER BIOLOGY & MEDICINE (2020)

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Article Immunology

2017 European guideline for the management of pelvic inflammatory disease

Jonathan Ross et al.

INTERNATIONAL JOURNAL OF STD & AIDS (2018)

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Review Pediatrics

The growing epidemic of sexually transmitted infections in adolescents: a neglected population

Chelsea L. Shannon et al.

CURRENT OPINION IN PEDIATRICS (2018)

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Article Dermatology

S2k-Leitlinie: HPV-assoziierte Läsionen der äußeren Genitalregion und des Anus - Genitalwarzen und Krebsvorstufen der Vulva, des Penis und der peri- und intraanalen Haut (Kurzfassung)

Gerd E. Gross et al.

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (2018)

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Review Obstetrics & Gynecology

Overview of the benefits and potential issues of the nonavalent HPV vaccine

Luciano Mariani et al.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2017)

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Article Immunology

2017 European guidelines for the management of genital herpes

Rajul Patel et al.

INTERNATIONAL JOURNAL OF STD & AIDS (2017)

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Article Obstetrics & Gynecology

Oral Human Papillomavirus in Women With High-Grade Cervical Intraepithelial Neoplasia

Linn Woelber et al.

JOURNAL OF LOWER GENITAL TRACT DISEASE (2017)

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Review Obstetrics & Gynecology

Sexually transmitted diseases and infertility

Danielle G. Tsevat et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2017)

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Review Obstetrics & Gynecology

Herpes Genitalis: Diagnosis, Treatment and Prevention

A. Sauerbrei

GEBURTSHILFE UND FRAUENHEILKUNDE (2016)

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Review Cell Biology

Chlamydia trachomatis Genital Infections

Catherine M. O'Connell et al.

MICROBIAL CELL (2016)

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Review Medicine, General & Internal

Pelvic Inflammatory Disease

Robert C. Brunham et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

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Article Medicine, General & Internal

A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women

E. A. Joura et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

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Article Obstetrics & Gynecology

Salpingitis. Laparscopic diagnostics, Chlamydia screening and intrauterine device in situ

U. B. Hoyme

GYNAKOLOGE (2015)

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Article Immunology

Pelvic Inflammatory Disease Current Concepts in Pathogenesis, Diagnosis and Treatment

Caroline Mitchell et al.

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA (2013)

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