期刊
ANNALS OF CARDIOTHORACIC SURGERY
卷 12, 期 3, 页码 253-258出版社
AME PUBLISHING COMPANY
DOI: 10.21037/acs-2023-avs1-0029
关键词
Valve-sparing aortic root replacement; pediatrics; congenital heart surgery; Marfan syndrome; Loeys-Dietz syndrome
This study retrospectively analyzed 17 pediatric patients who underwent aortic valve-sparing procedures at the Royal Children's Hospital, Melbourne between 2006 and 2016. The results showed that aortic valve-sparing surgery is a feasible option for pediatric patients, although it requires a highly skilled surgeon.
Background: Aortic valve-sparing procedures have been established as a mainstream treatment option for adult patients with aortic root aneurysms. However, data regarding their use in the pediatric population is limited. This study reports on our experience with aortic valve-sparing procedures in children. Methods: A retrospective review was conducted of all patients who underwent an aortic valve-sparing procedure at the Royal Children's Hospital, Melbourne, Australia between April 2006 and April 2016. Clinical and echocardiographic data were analyzed. Results: The study included 17 patients, with a median age of 15.7 years and a majority of patients being male (82.4%). The most common diagnosis was transposition of great arteries after arterial switch operation, followed by Loeys-Dietz syndrome and Marfan syndrome. Preoperative echocardiography showed more than moderate aortic regurgitation in 94.1% of the patients. The David procedure was performed in all 17 patients, with no mortality during follow-up. Reoperation was required in 29.4% of patients, and 23.5% required aortic valve replacement. Freedom from reoperation for aortic valve replacement at 1, 5, and 10 years was 93.8%, 93.8% and 68.2% respectively. Conclusions: Aortic valve-sparing surgery can be successfully performed in the pediatric population. However, it requires a highly skilled surgeon due to the often dysplastic or distorted nature of these valves and the need for additional procedures on the aortic valve leaflets.
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