Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study

Article Engineering, Environmental

Global trend of antimicrobial resistance in common bacterial pathogens in response to antibiotic consumption

Jie Hou et al.

Summary: There is an association between antibiotic consumption and antibiotic resistance globally, with low- and middle-income countries being major hotspots for resistance.

JOURNAL OF HAZARDOUS MATERIALS (2023)

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Article Immunology

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections

Pranita D. Tamma et al.

Summary: The Infectious Diseases Society of America (IDSA) has provided updated guidance on the treatment of antimicrobial-resistant infections, focusing on treating AmpC-producing Enterobacterales, carbapenem-resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia infections. The guidance is based on clinical experience, expert opinion, and a review of available literature, as published data on optimal treatment options are limited. This document emphasizes treatment approaches for infections in the United States, considering differences in resistance epidemiology and the availability of specific anti-infectives internationally.

CLINICAL INFECTIOUS DISEASES (2022)

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Article Immunology

Comparison of antimicrobial susceptibility interpretation among Enterobacteriaceae using CLSI and EUCAST breakpoints

Suravaram Swathi et al.

Summary: This study aimed to compare the antimicrobial susceptibility of various antibiotics using CLSI & EUCAST breakpoints, finding discrepancies in interpretation for most drugs. Only 3 antibiotics showed perfect agreement between the two guidelines, with major changes observed in the Intermediate category for others. Further research is needed to determine the clinical implications of these changes in antimicrobial susceptibility.

INDIAN JOURNAL OF MEDICAL MICROBIOLOGY (2021)

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Review Microbiology

Bacterial Antibiotic Resistance: The Most Critical Pathogens

Giuseppe Mancuso et al.

Summary: Overuse and misuse of antibiotics have accelerated the spread of antibiotic-resistant bacteria, leading to at least 700,000 deaths worldwide each year. Without new treatments, this number could rise to 10 million by 2050, posing a serious global health threat.

PATHOGENS (2021)

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Article Microbiology

Characterization of resistance mechanisms of Enterobacter cloacae Complex co-resistant to carbapenem and colistin

Shixing Liu et al.

Summary: This study found that the resistance mechanisms of carbapenem-resistant and colistin-resistant ECC strains do not overlap, but the presence of ECC strains carrying multiple resistance genes may pose a potential risk for the spread of carbapenem and colistin resistance.

BMC MICROBIOLOGY (2021)

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Review Microbiology