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Alternatives to Antimicrobial Treatment in Bovine Mastitis Therapy: A Review

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ANTIBIOTICS-BASEL
卷 12, 期 4, 页码 -

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MDPI
DOI: 10.3390/antibiotics12040683

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alternative treatment; antimicrobial stewardship; dairy cows; mastitis

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Despite preventive and therapeutic measures, mastitis remains a common health problem in dairy herds. In order to reduce the risks associated with antibiotic therapy, many scientific studies have explored non-antibiotic alternative approaches. These studies have identified novel, effective, and safe agents that have the potential to reduce antibiotic use and improve animal productivity and environmental protection.
Despite preventive and therapeutic measures, mastitis continues to be the most prevalent health problem in dairy herds. Considering the risks associated with antibiotic therapy, such as compromised effectiveness due to the emergence of resistant bacteria, food safety issues, and environmental impact, an increasing number of scientific studies have referred to the new therapeutic procedures that could serve as alternatives to conventional therapy. Therefore, the aim of this review was to provide insight into the currently available literature data in the investigation of non-antibiotic alternative approaches. In general, a vast number of in vitro and in vivo available data offer the comprehension of novel, effective, and safe agents with the potential to reduce the current use of antibiotics and increase animal productivity and environmental protection. Constant progress in this field could overcome treatment difficulties associated with bovine mastitis and considerable global pressure being applied on reducing antimicrobial therapy in animals.

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