期刊
PATHOGENS
卷 12, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/pathogens12050652
关键词
tuberculosis; biosocial; global health; antimicrobial resistance
类别
Despite progress in increasing access to TB diagnostics and treatment, the global burden of TB remains high, with a large number of latent TB infection carriers. The unintended consequence of increased treatment access is the dramatic rise in drug-resistant TB cases. A comprehensive paradigm shift for TB control in the twenty-first century requires a rethinking of the biosocial dynamics that impact the pathogenic disease.
With an estimated two billion people being carriers of latent tuberculosis infection (LTBI), the gains achieved by increasing access to diagnostics and treatment, although substantial, have had a modest impact on the global burden of tuberculosis (TB). At the same time, increased access to treatment has had the unintended consequence that drug-resistant TB (DR-TB) has increased dramatically. Earlier TB control strategies strongly emphasizing medical treatment have failed to address these issues effectively. The current strategy to eliminate TB by 2050 is accompanied by a call for a paradigm shift, emphasizing patient rights and equity more. Based on ethnographic fieldwork in Odisha, India, and global-level TB conferences, this paper contrasts the dynamics of global health policy and strategy-making with the lived realities of patients with DR-TB. A more thorough rethinking of the biosocial dynamics that impact the pathogenic disease is required to develop a comprehensive paradigm shift for TB control in the twenty-first century.
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