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IFN-Induced PARPs-Sensors of Foreign Nucleic Acids?

PATHOGENS (2023)

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Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

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PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

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Comparative analysis of viral RNA signatures on different RIG-I-like receptors

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Accessory Factors of Cytoplasmic viral RNA Sensors Required for Antiviral innate immune Response

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NATURE REVIEWS IMMUNOLOGY (2016)

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LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling

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CYTOKINE (2015)

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Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein

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Toll-like receptor 8 senses degradation products of single-stranded RNA

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Toll-like receptor 8 senses degradation products of single-stranded RNA

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PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression

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Interferon-Stimulated Poly(ADP-Ribose) Polymerases Are Potent Inhibitors of Cellular Translation and Virus Replication

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The 2′-5′-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2′-5′-Oligoadenylates Required for RNase L Activation

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Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity

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ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS Toxin Regulates Inflammasome Activity

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Family-wide analysis of poly(ADP-ribose) polymerase activity

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Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts

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DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

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BAL1 and Its Partner E3 Ligase, BBAP, Link Poly(ADP-Ribose) Activation, Ubiquitylation, and Double-Strand DNA Repair Independent of ATM, MDC1, and RNF8

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PARP-14 Binds Specific DNA Sequences to Promote Th2 Cell Gene Expression

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Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase

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Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains

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A systematic analysis of the PARP protein family identifies new functions critical for cell physiology

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Scavenger receptors in homeostasis and immunity

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New PARP Gene with an Anti-Alphavirus Function

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Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

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Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

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SCIENCE (2012)

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Uridine Composition of the Poly-U/UC Tract of HCV RNA Defines Non-Self Recognition by RIG-I

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ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

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Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

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LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

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Toward a unified nomenclature for mammalian ADP-ribosyltransferases

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TRENDS IN BIOCHEMICAL SCIENCES (2010)

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The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

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The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

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Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein

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The SARS-unique domain (SUD) of SARS coronavirus is an oligo(G)-binding protein

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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

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Activation of PKR: an open and shut case?

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PARP-10, a novel Myc-interacting protein with poly( ADP-ribose) polymerase activity, inhibits transformation

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Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold

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