期刊
PATHOGENS
卷 12, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/pathogens12030408
关键词
Staphylococcus aureus; septic arthritis; diagnosis; diabetes; tobacco; mPCR
类别
This paper presents a rare case of atypical septic arthritis caused by drug-resistant Staphylococcus aureus, and discusses current diagnostic methods, novel diagnostic techniques, and Staphylococcus aureus vaccine development for high-risk patients.
Septic arthritis is a synovial fluid and joint tissue infection with significant morbidity and mortality risk if not diagnosed and treated promptly. The most common pathogen to cause septic arthritis is Staphylococcus aureus, a Gram-positive bacterium. Although diagnostic criteria are in place to guide the diagnosis of staphylococcal septic arthritis, there is a lack of adequate sensitivity and specificity. Some patients present with atypical findings which make it difficult to diagnose and treat in time. In this paper, we present the case of a patient with an atypical presentation of recalcitrant staphylococcal septic arthritis in a native hip complicated by uncontrolled diabetes mellitus and tobacco usage. We review current literature on diagnosing S. aureus septic arthritis, novel diagnostic technique performance to guide future research and assist clinical suspicion, and current S. aureus vaccine development for at-risk patients.
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