期刊
MICROORGANISMS
卷 11, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/microorganisms11051239
关键词
Helicobacter pylori; whole genome sequencing; antimicrobial resistance; infectious disease
类别
Helicobacter pylori antimicrobial resistance is a significant public health issue. Whole genome sequencing can provide a comprehensive understanding of resistance mechanisms and improve treatment efficacy to prevent gastric cancer.
Helicobacter pylori antimicrobial resistance is a critical public health issue. Typically, antimicrobial resistance epidemiology reports include only the antimicrobial susceptibility test results for H. pylori. However, this phenotypic approach is less capable of answering queries related to resistance mechanisms and specific mutations found in particular global regions. Whole genome sequencing can help address these two questions while still offering quality control and is routinely validated against AST standards. A comprehensive understanding of the mechanisms of resistance should improve H. pylori eradication efforts and prevent gastric cancer.
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