☆ 4.7 Article

Rational Design of Multifunctional Ferulic Acid Derivatives Aimed for Alzheimer's and Parkinson's Diseases

ANTIOXIDANTS (2023)

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Ferulic Acid Induces Apoptosis of HeLa and Caski Cervical Carcinoma Cells by Down-Regulating the Phosphatidylinositol 3-Kinase (PI3K)/Akt Signaling Pathway

Liping Luo et al.

MEDICAL SCIENCE MONITOR (2020)

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Article Biochemistry & Molecular Biology

Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to biochemical effects

Claudia Pellerito et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2020)

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Article Chemistry, Medicinal

Alleviation of Liver Dysfunction, Oxidative Stress and Inflammation Underlies the Protective Effect of Ferulic Acid in Methotrexate-Induced Hepatotoxicity

Mozhdeh Roghani et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2020)

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Article Chemistry, Multidisciplinary

Computationally Designed Sesamol Derivatives Proposed as Potent Antioxidants

Laura M. Castro-Gonzalez et al.

ACS OMEGA (2020)

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Article Biochemistry & Molecular Biology

Gallic acid and ferulic acid protect the liver from thioacetamide-induced fibrosis in rats via differential expression of miR-21, miR-30 and miR-200 and impact on TGF-β1/Smad3 signaling

Rasha M. Hussein et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2020)

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Article Chemistry, Medicinal

Ferulic acid protects cardiomyocytes from TNF-α/cycloheximide-induced apoptosis by regulating autophagy

Chunxiao Li et al.

ARCHIVES OF PHARMACAL RESEARCH (2020)

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Article Chemistry, Physical

Iron ions chelation-based antioxidant potential vs. pro-oxidant risk of ferulic acid: A DFT study in aqueous phase

Dinh Hieu Truong et al.

COMPUTATIONAL AND THEORETICAL CHEMISTRY (2020)

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Article Engineering, Chemical

Biological Evaluation of Azetidine-2-One Derivatives of Ferulic Acid as Promising Anti-Inflammatory Agents

Maria Dragan et al.

PROCESSES (2020)

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Article Biochemistry & Molecular Biology

Ferulic acid confers protection on islet β cells and placental tissues of rats with gestational diabetes mellitus

Jian Zhao et al.

CELLULAR AND MOLECULAR BIOLOGY (2020)

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Article Biochemistry & Molecular Biology

Lipophilic ferulic acid derivatives protect PC12 cells against oxidative damage via modulating beta-amyloid aggregation and activating Nrf2 enzymes

Yu Wu et al.

FOOD & FUNCTION (2020)

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Article Biochemistry & Molecular Biology

Ferulic Acid Improves Depressive-Like Behavior in Prenatally-Stressed Offspring Rats via Anti-Inflammatory Activity and HPA Axis

Xingxing Zheng et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Medicine, Research & Experimental

Ferulic acid ameliorates nonalcoholic fatty liver disease and modulates the gut microbiota composition in high-fat diet fed ApoE-/- mice

Yunci Ma et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

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Article Biochemistry & Molecular Biology

A Ferulic Acid Derivative FXS-3 Inhibits Proliferation and Metastasis of Human Lung Cancer A549 Cells via Positive JNK Signaling Pathway and Negative ERK/p38, AKT/mTOR and MEK/ERK Signaling Pathways

Shi-Jun Yue et al.

MOLECULES (2019)

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Article Pharmacology & Pharmacy

A novel ferulic acid derivative attenuates myocardial cell hypoxia reoxygenation injury through a succinate dehydrogenase dependent antioxidant mechanism

Fei Wang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2019)

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Article Pharmacology & Pharmacy

The study of neuroprotective effect of ferulic acid based on cell metabolomics

Chun-li Yin et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2019)

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Article Food Science & Technology

Antidepressant-Like Effect of Ferulic Acid via Promotion of Energy Metabolism Activity

Kazunori Sasaki et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2019)

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Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain

Ahmed Montaser et al.

Oxidative Medicine and Cellular Longevity (2019)

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Article Chemistry, Medicinal

Cytotoxicity of New Ferulic-Acid Derivatives on Human Colon Carcinoma (HCT116) Cells

L. A. Bakholdina et al.

PHARMACEUTICAL CHEMISTRY JOURNAL (2019)

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Article Biochemistry & Molecular Biology

Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease

Zhipei Sang et al.

ACS CHEMICAL NEUROSCIENCE (2019)

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Article Plant Sciences

Ferulic acid confers tolerance against excess boron by regulating ROS levels and inducing antioxidant system in wheat leaves (Triticum aestivum)

Evren Yildiztugay et al.

ENVIRONMENTAL AND EXPERIMENTAL BOTANY (2019)

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Review Clinical Neurology

Inhibitors of MAO-B and COMT: their effects on brain dopamine levels and uses in Parkinson's disease

John P. M. Finberg

JOURNAL OF NEURAL TRANSMISSION (2019)

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Review Nutrition & Dietetics

Anti-hypertensive Effect of Cereal Antioxidant Ferulic Acid and Its Mechanism of Action

Md Ashraful Alam

FRONTIERS IN NUTRITION (2019)

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Article Biochemistry & Molecular Biology

In vitro and in vivo antithrombotic and cytotoxicity effects of ferulic acid

Jun-Hui Choi et al.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2018)

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Article Medicine, Research & Experimental

Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice

Salma Mukhtar Mir et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

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Article Oncology

The anticancer effects of ferulic acid is associated with induction of cell cycle arrest and autophagy in cervical cancer cells

Jinhua Gao et al.

CANCER CELL INTERNATIONAL (2018)

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Article Chemistry, Medicinal

Preparation, characterization, and in vivo evaluation of nano formulations of ferulic acid in diabetic wound healing

Ujjawal Bairagi et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2018)

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Article Food Science & Technology

Ameliorative role of ferulic acid against diabetes associated oxidative stress induced spleen damage

Sumit Ghosh et al.

FOOD AND CHEMICAL TOXICOLOGY (2018)

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Article Food Science & Technology

Computational and experimental validation of antioxidant properties of synthesized bioactive ferulic acid derivatives

Oluyomi Stephen Adeyemi et al.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES (2018)

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Article Materials Science, Biomaterials

In-vivo sustained release of nanoencapsulated ferulic acid and its impact in induced diabetes

Richa Panwar et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

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Article Chemistry, Multidisciplinary

Theoretical study of ferulic acid dimer derivatives: bond dissociation enthalpy, spin density, and HOMO-LUMO analysis

Luis Hernandez-Garcia et al.

STRUCTURAL CHEMISTRY (2018)

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Review Dermatology

Antioxidant Properties of Ferulic Acid and Its Possible Application

Kamila Zdunska et al.

SKIN PHARMACOLOGY AND PHYSIOLOGY (2018)

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Article Urology & Nephrology

Ameliorative effect of ferulic acid on gentamicin-induced nephrotoxicity in a rat model; role of antioxidant effects

Amin Hasanvand et al.

JOURNAL OF RENAL INJURY PREVENTION (2018)

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Article Multidisciplinary Sciences

Molecular Docking of Ferulic Acid Derivatives on P2Y12 Receptor and their ADMET Prediction

Juni Ekowati et al.

JOURNAL OF MATHEMATICAL AND FUNDAMENTAL SCIENCES (2018)

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Article Chemistry, Medicinal

Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

Zhipei Sang et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

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Article Immunology

Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress

Ya-Min Liu et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2017)

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Article Medicine, Research & Experimental

Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo

Zhongkun Ren et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)

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Article Chemistry, Medicinal

Quantum chemical, ADMET and molecular docking studies of ferulic acid amide derivatives with a novel anticancer drug target

Naresh Kumar et al.

MEDICINAL CHEMISTRY RESEARCH (2017)

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Article Biochemistry & Molecular Biology

Ferulic Acid Supplementation for Management of Depression in Epilepsy

Tanveer Singh et al.

NEUROCHEMICAL RESEARCH (2017)

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Article Agronomy

Design, synthesis, antiviral bioactivity and three-dimensional quantitative structure-activity relationship study of novel ferulic acid ester derivatives containing quinazoline moiety

Zengxue Wu et al.

PEST MANAGEMENT SCIENCE (2017)

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Article Chemistry, Physical

Estimation of empirically fitted parameters for calculating pK a values of thiols in a fast and reliable way

Adriana Perez-Gonzalez et al.

THEORETICAL CHEMISTRY ACCOUNTS (2017)

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Review Pharmacology & Pharmacy

Chemical Properties of Caffeic and Ferulic Acids in Biological System: Implications in Cancer Therapy. A Review

Sarah S. Damasceno et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

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Article Chemistry, Medicinal

Synthesis, antiviral activity, and molecular docking study of trans-ferulic acid derivatives containing acylhydrazone moiety

Zhenzhen Wang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

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Article Biochemistry & Molecular Biology

Water-soluble ferulic acid derivatives improve amyloid-β-induced neuronal cell death and dysmnesia through inhibition of amyloid-β aggregation

Masaki Kikugawa et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2016)

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Article Oncology

Anti-proliferative and anti-invasive effects of ferulic acid in TT medullary thyroid cancer cells interacting with URG4/URGCP

Yavuz Dodurga et al.

TUMOR BIOLOGY (2016)

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Article Biochemistry & Molecular Biology

Ferulic acid, a natural polyphenol, alleviates insulin resistance and hypertension in fructose fed rats: Effect on endothelial-dependent relaxation

Hany El-Bassossy et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2016)

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Article Pharmacology & Pharmacy

Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling

Qian Hong et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2016)

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Article Pharmacology & Pharmacy

Protective effects of a dimeric derivative of ferulic acid in animal models of Alzheimer's disease

Jun-Sub Jung et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2016)

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Article Genetics & Heredity

Ferulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro

Umut Fahrioglu et al.

GENE (2016)

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Article Cell Biology

The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity

Fethullah Gerin et al.

INFLAMMATION (2016)

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Article Food Science & Technology

Ferulic acid ameliorates memory impairment in d-galactose-induced aging mouse model

Honggai Yang et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2016)

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Article Chemistry, Medicinal

Empirically Fitted Parameters for Calculating pKa Values with Small Deviations from Experiments Using a Simple Computational Strategy

Annia Galano et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2016)

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A theoretical study on antioxidant activity of ferulic acid and its ester derivatives

Romesh Borgohain et al.

JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY (2016)

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Article Chemistry, Medicinal

Ferulic acid amide derivatives as anticancer and antioxidant agents: synthesis, thermal, biological and computational studies

Naresh Kumar et al.

MEDICINAL CHEMISTRY RESEARCH (2016)

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Article Chemistry, Physical

Photodynamics of potent antioxidants: ferulic and caffeic acids

Michael D. Horbury et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)

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The 2H+/2e- free radical scavenging mechanisms of uric acid: thermodynamics of N-H bond cleavage

Ana Amic et al.

COMPUTATIONAL AND THEORETICAL CHEMISTRY (2016)

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Review Pharmacology & Pharmacy

Inhibitors of MAO-A and MAO-B in Psychiatry and Neurology

John P. M. Finberg et al.

FRONTIERS IN PHARMACOLOGY (2016)

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Article Biochemistry & Molecular Biology

Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate

Keylla C. Machado et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2015)

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Review Pharmacology & Pharmacy

Catechol-O-Methyltransferase Inhibitors in Parkinson's Disease

Thomas Mueller

DRUGS (2015)

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Article Endocrinology & Metabolism

Ferulic acid chronic treatment exerts antidepressant-like effect: role of antioxidant defense system

Juliana Lenzi et al.

METABOLIC BRAIN DISEASE (2015)

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Article Pharmacology & Pharmacy

Augmentation of ferulic acid-induced vasorelaxation with aging and its structure importance in thoracic aorta of spontaneously hypertensive rats

Toshihiko Fukuda et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2015)

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Article Oncology

Assessment of the anticancer mechanism of ferulic acid via cell cycle and apoptotic pathways in human prostate cancer cell lines

Canan Eroglu et al.

TUMOR BIOLOGY (2015)

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Article Chemistry, Multidisciplinary

Design, Synthesis, and In Vitro Antiplatelet Aggregation Activities of Ferulic Acid Derivatives

Peng-Xuan Zhang et al.

JOURNAL OF CHEMISTRY (2015)

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Article Endocrinology & Metabolism

Antidepressant-like effects of ferulic acid: involvement of serotonergic and norepinergic systems

Jianliang Chen et al.

METABOLIC BRAIN DISEASE (2015)

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Synthesis and antimicrobial evaluation of ferulic acid derivatives

Anurag Khatkar et al.

RESEARCH ON CHEMICAL INTERMEDIATES (2015)

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Review Pharmacology & Pharmacy

Structure-based drug design of catechol-O-methyltransferase inhibitors for CNS disorders

Zhiguo Ma et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2014)

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Article Chemistry, Medicinal

Medicinal Chemistry of Catechol O-Methyltransferase (COMT) Inhibitors and Their Therapeutic Utility

Laszlo E. Kiss et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

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Article Biochemistry & Molecular Biology

Influence of different free radicals on scavenging potency of gallic acid

Jelena Dorovic et al.

JOURNAL OF MOLECULAR MODELING (2014)

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Vertical Ionization Energies of Free Radicals and Electron Detachment Energies of Their Anions: A Comparison of Direct and Indirect Methods Versus Experiment

Adriana Perez-Gonzalez et al.

JOURNAL OF PHYSICAL CHEMISTRY A (2014)

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Review Oncology

Monoamine oxidase inhibitors: Promising therapeutic agents for Alzheimer's disease (Review)

Zhiyou Cai

MOLECULAR MEDICINE REPORTS (2014)

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Review Pharmacology & Pharmacy

Ferulic acid and derivatives: molecules with potential application in the pharmaceutical field

Livia Brenelli de Paiva et al.

BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)

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Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

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CURRENT NEUROPHARMACOLOGY (2013)

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Understanding the Molecular Properties and Metabolism of Top Prescribed Drugs

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CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)

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Ferulic Acid Improves Cardiovascular and Kidney Structure and Function in Hypertensive Rats

Md Ashraful Alam et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2013)

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Article Infectious Diseases

Antibacterial Activity and Mode of Action of Ferulic and Gallic Acids Against Pathogenic Bacteria

Anabela Borges et al.

MICROBIAL DRUG RESISTANCE (2013)

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Article Biochemical Research Methods

Catechol-O-methyltransferase in complex with substituted 3′-deoxyribose bisubstrate inhibitors

Manuel Ellermann et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)

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Article Chemistry, Medicinal

Biological activity evaluation and structure-activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer

Weixia Li et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

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Article Chemistry, Medicinal

Is chemical synthetic accessibility computationally predictable for drug and lead-like molecules? A comparative assessment between medicinal and computational chemists

Pascal Bonnet

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)

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Article Chemistry, Medicinal

Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands

Jonah Cheung et al.

JOURNAL OF MEDICINAL CHEMISTRY (2012)

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Article Chemistry, Physical

On the peroxyl scavenging activity of hydroxycinnamic acid derivatives: mechanisms, kinetics, and importance of the acid-base equilibrium

Jorge Rafael Leon-Carmona et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2012)

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Article Chemistry, Medicinal

Lipophilic Caffeic and Ferulic Acid Derivatives Presenting Cytotoxicity against Human Breast Cancer Cells

Teresa L. Serafim et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2011)

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Article Chemistry, Physical

Physicochemical Insights on the Free Radical Scavenging Activity of Sesamol: Importance of the Acid/Base Equilibrium

Annia Galano et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2011)

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Article Biotechnology & Applied Microbiology

Probing the links between in vitro potency, ADMET and physicochemical parameters

M. Paul Gleeson et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

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Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain MAO-A by CX157

Joanna S. Fowler et al.

NEUROPSYCHOPHARMACOLOGY (2010)

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Article Chemistry, Applied

In vitro and in vivo antioxidant properties of ferulic acid: A comparative study with other natural oxidation inhibitors

Shirou Itagaki et al.

FOOD CHEMISTRY (2009)

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Determination of Dissociation Constants of Some Hydroxylated Benzoic and Cinnamic Acids in Water from Mobility and Spectroscopic Data Obtained by CE-DAD

Sabriye P. Ozkorucuklu et al.

JOURNAL OF CHEMICAL AND ENGINEERING DATA (2009)

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Review Chemistry, Physical

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

Aleksandr V. Marenich et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2009)

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Article Agriculture, Multidisciplinary

Novel effects of a single administration of ferulic acid on the regulation of blood pressure and the hepatic lipid metabolic profile in stroke-prone spontaneously hypertensive rats

Ardiansyah et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)

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Article Biochemistry & Molecular Biology

Sequestration of Copper from β-Amyloid Promotes Selective Lysis by Cyclen-Hybrid Cleavage Agents

Wei-hui Wu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

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Article Chemistry, Medicinal

Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis

Hao Zhu et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)

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Article Chemistry, Medicinal

Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: Safinamide and coumarin analogs

Claudia Binda et al.

JOURNAL OF MEDICINAL CHEMISTRY (2007)

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Article Biochemistry & Molecular Biology

Structure and reaction based evaluation of synthetic accessibility

Krisztina Boda et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2007)

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Article Peripheral Vascular Disease

Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats

Atsushi Suzuki et al.

AMERICAN JOURNAL OF HYPERTENSION (2007)

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Article Chemistry, Applied

Preparation of ferulic acid derivatives and evaluation of their xanthine oxidase inhibition activity

Feng Wang et al.

NATURAL PRODUCT RESEARCH (2007)

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Review Nutrition & Dietetics

Ferulic acid: Therapeutic potential through its antioxidant property

Marimuthu Srinivasan et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2007)

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Review Chemistry, Physical

Design of density functionals by combining the method of constraint satisfaction with parametrization for thermochemistry, thermochemical kinetics, and noncovalent interactions

Y Zhao et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2006)

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Review Biochemistry & Molecular Biology

Structure and mechanism of monoamine oxidase

DE Edmondson et al.

CURRENT MEDICINAL CHEMISTRY (2004)

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UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

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Molecular properties that influence the oral bioavailability of drug candidates

DF Veber et al.

JOURNAL OF MEDICINAL CHEMISTRY (2002)

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