4.7 Article

Flavonoid Extract from Seed Residues of Hippophae rhamnoides ssp. sinensis Protects against Alcohol-Induced Intestinal Barrier Dysfunction by Regulating the Nrf2 Pathway

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Food Science & Technology

Bioactive compounds, health benefits and functional food products of sea buckthorn: a review

Kewen Wang et al.

Summary: Sea buckthorn, recognized as a medicine food homology fruit by China's National Health Commission, is rich in nutrients and bioactive compounds, with various health benefits such as improving cardiovascular conditions, anti-diabetic and anti-obesity activity. This review compiled a database of phytochemical compounds in sea buckthorn, summarizing its benefits and mechanisms of anti-oxidation and anti-inflammation.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Article Food Science & Technology

Comparative assessment of phenolics, antioxidant and antiproliferative activities between Hippophae rhamnoides ssp. sinensis and H. tibetana leaf in Qinghai-Tibet Plateau

Juan Wei et al.

Summary: Both sea buckthorn leaf of Hippophae rhamnoides ssp. sinensis (Rha) and H. tibetana (Tib) exhibited high levels of total phenolic and flavonoid content, with Rha showing significantly higher levels. The presence of 66 phenolic compounds, including ellagic acid, rutin, and other compounds, was detected in sea buckthorn leaf for the first time. The aqueous ethanol extracts of sea buckthorn leaf showed strong antioxidant properties and anti-proliferation activity against HepG2 cells, with Rha showing stronger effects due to its higher content of total phenolic and flavonoid profiles.

FOOD BIOSCIENCE (2022)

Article Chemistry, Applied

Phenolic compositions and antioxidant activities of Hippophae tibetana and H. rhamnoides ssp. sinensis berries produced in Qinghai-Tibet Plateau

Juan Wei et al.

Summary: The phenolic ingredients of Hippophae tibetana and H. rhamnoides ssp. sinensis berries from the Qinghai-Tibet Plateau were identified. The results showed that both berries had high levels of total phenolic and flavonoid compounds, with Rha berries having higher contents. Additionally, Rha berries had higher levels of flavonols, while Tib berries had higher levels of flavanols. The phenolic extracts of both berries exhibited strong antioxidant properties, with Rha berries showing stronger effects due to their higher levels of phenolic and flavonoid profiles.

FOOD CHEMISTRY-X (2022)

Article Cell Biology

Prophylactic Treatment of Probiotic and Metformin Mitigates Ethanol-Induced Intestinal Barrier Injury: In Vitro, In Vivo, and In Silico Approaches

Farhin Patel et al.

Summary: The study demonstrates that the combination of probiotic V and metformin can alleviate ethanol-induced intestinal barrier dysfunction and oxidative stress, while promoting anti-inflammatory responses.

MEDIATORS OF INFLAMMATION (2021)

Article Chemistry, Applied

Flavonoids and caffeoylquinic acids in Chrysanthemum morifolium Ramat flowers: A potentially rich source of bioactive compounds

Sha Chen et al.

Summary: The study analyzed various chemical compounds in chrysanthemums using liquid chromatography mass spectrometry, finding a correlation between acacetin and kaempferol content and flower color, as well as indicating that chrysanthemums are rich in flavonoids and carotenoids. The results contribute to a better understanding of flavonoid biosynthesis and flower color formation mechanisms.

FOOD CHEMISTRY (2021)

Article Agriculture, Multidisciplinary

Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways

Jinwen Yuan et al.

Summary: The study showed that luteolin could alleviate ethanol-induced intestinal barrier damage by regulating the expression of tight junction proteins and inhibiting key signaling pathways. Additionally, luteolin acted as an indirect antioxidant to relieve oxidative damage and improve tight junction function.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Review Nutrition & Dietetics

Alcohol's Impact on the Gut and Liver

Keith Pohl et al.

Summary: Alcohol is closely linked to the digestive system, affecting gut microbiome and liver function and structure. Excessive alcohol use can result in important micronutrient deficiencies and progression of liver disease, even leading to liver cancer and high mortality rates among chronic liver disease patients.

NUTRIENTS (2021)

Article Food Science & Technology

Composition analysis and antioxidant activity evaluation of a high purity oligomeric procyanidin prepared from sea buckthorn by a green method

Yulian Zhu et al.

Summary: The research successfully obtained sea buckthorn Procyanidin (SBP) using a green extraction technique, and analyzed its structure, antioxidant properties, and synergistic effects with vitamin C. Results showed that SBP has promising potential as a natural antioxidant with superior scavenging capacity and synergistic effects with vitamin C.

CURRENT RESEARCH IN FOOD SCIENCE (2021)

Review Nutrition & Dietetics

Health-Promoting Properties of Proanthocyanidins for Intestinal Dysfunction

Carlos Gonzalez-Quilen et al.

NUTRIENTS (2020)

Article Food Science & Technology

Puerarin prevents epithelial tight junction dysfunction induced by ethanol in Caco-2 cell model

Si-yan Che et al.

JOURNAL OF FUNCTIONAL FOODS (2020)

Review Cell Biology

A Protective Role of the NRF2-Keap1 Pathway in Maintaining Intestinal Barrier Function

Zhiyong Wen et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

Review Biochemistry & Molecular Biology

Lipid Oxidation Products in the Pathogenesis of Inflammation-related Gut Diseases

Barbara Sottero et al.

CURRENT MEDICINAL CHEMISTRY (2018)

Review Food Science & Technology

Intestinal Barrier Function in Chronic Kidney Disease

Bjorn Meijers et al.

TOXINS (2018)

Article Oncology

Interplay between tight junctions & adherens junctions

Hannah K. Campbell et al.

EXPERIMENTAL CELL RESEARCH (2017)

Review Gastroenterology & Hepatology

Oxidative stress, antioxidants and intestinal calcium absorption

Gabriela Diaz de Barboza et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2017)

Review Medicine, Research & Experimental

Studies on oxidants and antioxidants with a brief glance at their relevance to the immune system

Banafsheh Amir Aslani et al.

LIFE SCIENCES (2016)

Article Integrative & Complementary Medicine

Anti-Inflammatory Effects of Cumin Essential Oil by Blocking JNK, ERK, and NF-κB Signaling Pathways in LPS-Stimulated RAW 264.7 Cells

Juan Wei et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)

Article Agriculture, Multidisciplinary

Analysis of Lipophilic and Hydrophilic Bioactive Compounds Content in Sea Buckthorn (Hippophae rhamnoides L.) Berries

Miroslawa Teleszko et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

Review Biochemistry & Molecular Biology

Downregulation of tumor necrosis factor and other proinflammatory biomarkers by polyphenols

Subash C. Gupta et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2014)

Review Chemistry, Multidisciplinary

Superoxide Dismutases and Superoxide Reductases

Yuewei Sheng et al.

CHEMICAL REVIEWS (2014)

Article Agriculture, Multidisciplinary

Polyphenols Protect the Epithelial Barrier Function of Caco-2 Cells Exposed to Indomethacin through the Modulation of Occludin and Zonula Occludens-1 Expression

Catalina Carrasco-Pozo et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

Article Nutrition & Dietetics

Supplemental Naringenin Prevents Intestinal Barrier Defects and Inflammation in Colitic Mice

Tomoyo Azuma et al.

JOURNAL OF NUTRITION (2013)

Review Nutrition & Dietetics

Ethanol metabolism and its effects on the intestinal epithelial barrier

Elhaseen E. Elamin et al.

NUTRITION REVIEWS (2013)

Review Nutrition & Dietetics

Nutritional Attributes and Health Application of Seabuckthorn (Hippophae rhamnoides L.) - A Review

Tsering Stobdan et al.

CURRENT NUTRITION & FOOD SCIENCE (2013)

Article Food Science & Technology

HPLC-DAD-MS/MS profiling of antioxidant flavonoid glycosides in sea buckthorn (Hippophae rhamnoides L.) seeds

Ranjith Arimboor et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2012)

Article Agriculture, Multidisciplinary

Differential Effects of Flavonoids on Barrier Integrity in Human Intestinal Caco-2 Cells

Sakino Noda et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2012)

Article Agriculture, Multidisciplinary

Hypolipidaemic and hypoglycaemic effects of total flavonoids from seed residues of Hippophae rhamnoides L. in mice fed a high-fat diet

Jiesi Wang et al.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2011)

Review Biochemistry & Molecular Biology

Nrf2:INrf2 (Keap1) signaling in oxidative stress

James W. Kaspar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Review Allergy

Intestinal barrier function: Molecular regulation and disease pathogenesis

Katherine R. Groschwitz et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)

Review Biochemistry & Molecular Biology

Transmembrane proteins of tight junctions

Hideki Chiba et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)

Article Chemistry, Applied

Radical-scavenging proanthocyanidins from sea buckthorn seed

Jinling Fan et al.

FOOD CHEMISTRY (2007)

Article Nutrition & Dietetics

Intestinal permeability and oxidative stress in patients with alcoholic pellagra

MSrcia Varella Morandi Junqueira-Francoa et al.

CLINICAL NUTRITION (2006)

Review Gastroenterology & Hepatology

Alcohol and oxidative liver injury

A Dey et al.

HEPATOLOGY (2006)

Article Endocrinology & Metabolism

Intestinal barrier function

DC Baumgart et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2002)