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ADVANCES IN NUTRITION (2011)
Neuroprotective Mechanism of Mitochondrial Ferritin on 6-Hydroxydopamine-Induced Dopaminergic Cell Damage: Implication for Neuroprotection in Parkinson's Disease
Zhen-Hua Shi et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron
Darius J. R. Lane et al.
BIOCHEMICAL JOURNAL (2010)
Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease
James A. Duce et al.
CELL (2010)
Two to Tango: Regulation of Mammalian Iron Metabolism
Matthias W. Hentze et al.
CELL (2010)
Role of hepcidin in murine brain iron metabolism
S. -M. Wang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Gestational and Neonatal Iron Deficiency Alters Apical Dendrite Structure of CA1 Pyramidal Neurons in Adult Rat Hippocampus
Katyarina E. Brunette et al.
DEVELOPMENTAL NEUROSCIENCE (2010)
Effectiveness of iron repletion in the diet for the optic nerve development of anaemic rats
A. S. DeMaman et al.
EYE (2010)
Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1
Jerome A. Roth et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Iron Deficiency Anemia and Cognitive Function in Infancy
R. Colin Carter et al.
PEDIATRICS (2010)
Consequences of Low Neonatal Iron Status Due to Maternal Diabetes Mellitus on Explicit Memory Performance in Childhood
Tracy Riggins et al.
DEVELOPMENTAL NEUROPSYCHOLOGY (2009)
Divalent metal transporter 1 is involved in amyloid precursor protein processing and A beta generation
Wei Zheng et al.
FASEB JOURNAL (2009)
MRI and Histological Analysis of Beta-Amyloid Plaques in Both Human Alzheimer's Disease and APP/PS1 Transgenic Mice
Mark D. Meadowcroft et al.
JOURNAL OF MAGNETIC RESONANCE IMAGING (2009)
Intranasal Deferoxamine Provides Increased Brain Exposure and Significant Protection in Rat Ischemic Stroke
Leah R. Hanson et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in MES23.5 cells
Shuzhen Zhang et al.
NEUROBIOLOGY OF AGING (2009)
Chelation Therapy for Neurodegenerative Diseases
Silvia Bolognin et al.
MEDICINAL RESEARCH REVIEWS (2009)
Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins
Tracey A. Rouault et al.
METABOLIC BRAIN DISEASE (2009)
Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993-2005
Erin McLean et al.
PUBLIC HEALTH NUTRITION (2009)
The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies
Robert A. Philibert et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2008)
Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network
Martina U. Muckenthaler et al.
Annual Review of Nutrition (2008)
Glutaredoxin systems
Christopher Horst Lillig et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
A potential pathogenetic role of iron in Alzheimer's disease
Laura Silvestri et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Tim-2 is the receptor for H-ferritin on oligodendrocytes
Bozho Todorich et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Early-Life Iron Deficiency Anemia Alters Neurotrophic Factor Expression and Hippocampal Neuron Differentiation in Male Rats
Phu V. Tran et al.
JOURNAL OF NUTRITION (2008)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett et al.
NATURE GENETICS (2008)
Regulation of iron acquisition and storage: consequences for iron-linked disorders
Ivana De Domenico et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Deferoxamine decreases the excitatory amino acid levels and improves the histological outcome in the hippocampus of neonatal rats after hypoxia-ischemia
Georgios Papazisis et al.
PHARMACOLOGICAL RESEARCH (2008)
Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1α and erythropoietin
Yun-Xia Li et al.
Neuroscience Bulletin (2008)
Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease
Ashley D. Reynolds et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications
Yang-Sung Sohn et al.
BLOOD (2008)
Development and iron-dependent expression of hephaestin in different brain regions of rats
Zhong-Ming Qian et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Iron deficiency and child development
Betsy Lozoff
FOOD AND NUTRITION BULLETIN (2007)
Brain iron metabolism: Neurobiology and neurochemistry
Ya Ke et al.
PROGRESS IN NEUROBIOLOGY (2007)
Oxidative stress-induced phosphorylation, degradation and aggregation of α-synuclein are linked to upregulated CK2 and cathepsin D
Makio Takahashi et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Ferritin: a novel mechanism for delivery of iron to the brain and other organs
J. Fisher et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Selective iron chelation in Friedreich ataxia:: biologic and clinical implications
Nathalie Boddaert et al.
BLOOD (2007)
The apoptosome: signalling platform of cell death
Stefan J. Riedl et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Recent evidence from human and animal studies regarding iron status and infant development
John Beard
JOURNAL OF NUTRITION (2007)
Perinatal iron deficiency results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus
Erik S. Carlson et al.
HIPPOCAMPUS (2007)
Early iron deficiency alters sensorimotor development and brain monoamines in rats
Erica L. Unger et al.
JOURNAL OF NUTRITION (2007)
The 5 '-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element
A. L. Friedlich et al.
MOLECULAR PSYCHIATRY (2007)
Characterization of the Rab8-specific membrane traffic route linked to protrusion formation
Katarina Hattula et al.
JOURNAL OF CELL SCIENCE (2006)
Fenton chemistry and iron chelation under physiologically relevant conditions: Electrochemistry and kinetics
Martin Merkofer et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2006)
Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice
Suh Young Jeong et al.
JOURNAL OF NEUROSCIENCE (2006)
NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1
Jaime H. Cheah et al.
NEURON (2006)
Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats
Barbara T. Felt et al.
BEHAVIOURAL BRAIN RESEARCH (2006)
Oral chelators deferasirox and defefiprone for transfusional iron overload in thalassen a major: new data, new questions
EJ Neufeld
BLOOD (2006)
Long-lasting neural and behavioral effects of iron deficiency in infancy
Betsy Lozoff et al.
NUTRITION REVIEWS (2006)
Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders
S Mandel et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2006)
Reactive macrophages increase oxidative stress and alpha-synuclein nitration during death of dopaminergic neuronal cells in co-culture: Relevance to Parkinson's disease
S Shavali et al.
NEUROCHEMICAL RESEARCH (2006)
Perinatal nutritional iron deficiency permanently impairs hippocampus-dependent trace fear conditioning in rats
MD McEchron et al.
NUTRITIONAL NEUROSCIENCE (2005)
Controlled elimination of intracellular H2O2:: Regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification
SG Rhee et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
L Chen et al.
NATURE NEUROSCIENCE (2005)
Multifunctional activities of green tea catechins in neuroprotection - Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway
SA Mandel et al.
NEUROSIGNALS (2005)
Fetal iron deficiency disrupts the maturation of synaptic function and efficacy in area CAI of the developing rat hippocampus
LA Jorgenson et al.
HIPPOCAMPUS (2005)
Brain capillary endothelium and choroid plexus epithelium regulate transport of transferrin-bound and free iron into the rat brain
R Deane et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
EG Meyron-Holtz et al.
EMBO JOURNAL (2004)
Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration
P Hahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models
E Ortiz et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
A Zimprich et al.
NEURON (2004)
Functional consequences of α-synuclein tyrosine nitration -: Diminished binding to lipid vesicles and increased fibril formation
R Hodara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats
JL Beard et al.
DEVELOPMENTAL NEUROSCIENCE (2003)
Dopaminergic cell death precedes iron elevation in MPTP-injected monkeys
Y He et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
SY Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain
AJM Siddappa et al.
PEDIATRIC RESEARCH (2003)
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Effects of coenzyme Q10 in early Parkinson disease -: Evidence of slowing of the functional decline
CW Shults et al.
ARCHIVES OF NEUROLOGY (2002)
Amyloid-β oligomers:: their production, toxicity and therapeutic inhibition
DM Walsh et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
Dopamine-dependent neurotoxicity of α-synuclein:: A mechanism for selective neurodegeneration in Parkinson disease
J Xu et al.
NATURE MEDICINE (2002)
Aceruloplasminemia:: new clinical, pathophysiological and therapeutic insights
O Loréal et al.
JOURNAL OF HEPATOLOGY (2002)
Magnesium inhibits spontaneous and iron-induced aggregation of α-synuclein
N Golts et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cytochrome c release from mitochondria proceeds by a two-step process
M Ott et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
α-Synuclein is phosphorylated in synucleinopathy lesions
H Fujiwara et al.
NATURE CELL BIOLOGY (2002)
Lactoferrin is synthesized by activated microglia in the human substantia nigra and its synthesis by the human microglial CHME cell line is upregulated by tumor necrosis factor α or 1-methyl-4-phenylpyridinium treatment
C Fillebeen et al.
MOLECULAR BRAIN RESEARCH (2001)
Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP)
M Takanashi et al.
PARKINSONISM & RELATED DISORDERS (2001)
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
T LaVaute et al.
NATURE GENETICS (2001)
Oxidative regulation of fatty acid-induced tau polymerization
TC Gamblin et al.
BIOCHEMISTRY (2000)
Glial cells contribute more to iron and aluminum accumulation but are more resistant to oxidative stress than neuronal cells
S Oshiro et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2000)
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson et al.
SCIENCE (2000)
Sequestration of iron by Lewy bodies in Parkinson's disease
RJ Castellani et al.
ACTA NEUROPATHOLOGICA (2000)
Chronic marginal iron intakes during early development in mice alter brain iron concentrations and behavior despite postnatal iron supplementation
CL Kwik-Uribe et al.
JOURNAL OF NUTRITION (2000)
Metals and neuroscience
AI Bush
CURRENT OPINION IN CHEMICAL BIOLOGY (2000)
The neuroprotective effect of deferoxamine in the hypoxic-ischemic immature mouse brain
DP Sarco et al.
NEUROSCIENCE LETTERS (2000)
Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy
B Lozoff et al.
PEDIATRICS (2000)
Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain
BN Patel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Transferrin and transferrin receptor function in brain barrier systems
T Moos et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2000)
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