☆ 4.7 Article

Punica granatum L. Extract Shows Cardioprotective Effects Measured by Oxidative Stress Markers and Biomarkers of Heart Failure in an Animal Model of Metabolic Syndrome

ANTIOXIDANTS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Cell Biology

Punica granatum L. Polyphenolic Extract as an Antioxidant to Prevent Kidney Injury in Metabolic Syndrome Rats

Anna Radajewska et al.

Summary: Obesity and metabolic syndrome are rapidly increasing health problems, and they contribute to the development of multiple comorbidities, including kidney diseases. Oxidative stress is an important component of metabolic syndrome and is also involved in kidney dysfunction and injury. The study confirms the usefulness of pomegranate polyphenols in treating metabolic syndrome and preventing kidney damage.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2023)

添加到收藏夹

Article Pharmacology & Pharmacy

Pomegranate peel extract protects against the development of diabetic cardiomyopathy in rats by inhibiting pyroptosis and downregulating LncRNA-MALAT1

Mariam Ali Abo-Saif et al.

Summary: This study investigated the protective effect of pomegranate peel extract (PPE) on diabetic cardiomyopathy in rats. The results showed that PPE exhibited antioxidant, anti-inflammatory, and antifibrotic properties, and improved cardiac structure and function. The protective effect of PPE may be attributed to the inhibition of pyroptosis and downregulation of lncRNA-MALAT1.

FRONTIERS IN PHARMACOLOGY (2023)

添加到收藏夹

Review Biochemistry & Molecular Biology

Metabolic Syndrome: Updates on Pathophysiology and Management in 2021

Gracia Fahed et al.

Summary: Metabolic syndrome is a cluster of metabolic dysregulations associated with insulin resistance and chronic low-grade inflammation. If left untreated, it significantly increases the risk of developing diabetes and cardiovascular diseases. However, many aspects of Metabolic syndrome are still not completely understood, and many questions remain unanswered. This review provides a comprehensive overview of the historical background, epidemiology, histopathology, pathophysiology, management, and prevention of Metabolic syndrome.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Ongoing and potential novel trends of pomegranate fruit peel; a comprehensive review of its health benefits and future perspectives as nutraceutical

Heba A. Fahmy et al.

Summary: Pomegranate peel, previously considered as waste, is now recognized as a rich source of bioactive compounds with promising health benefits. Recent research has shown that pomegranate peel exhibits various pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, anti-osteoporosis, antihyperlipidemic, and anticancer effects. Its potential health benefits are attributed to its phenolic and polysaccharide content, as well as its biotransformed metabolites.

JOURNAL OF FOOD BIOCHEMISTRY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nutritional and phytochemical profile of pomegranate (Wonderful variety) peel and its effects on hepatic oxidative stress and metabolic alterations

Eunice A. Akuru et al.

Summary: The study evaluates the antioxidant, nutritional, and phytochemical profiles of the Wonderful pomegranate peel, showing its potential as a source of functional nutrients and phenolic antioxidants. The peel exhibits potent antioxidant activities, preventing oxidative stress-induced damage in liver cells and tissues. Additionally, metabolomics analysis reveals beneficial metabolic alterations following treatment with the peel extract, suggesting its potential in improving overall body function and mitigating hepatic oxidative damage.

JOURNAL OF FOOD BIOCHEMISTRY (2022)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Twenty-year trends in heart failure among US adults, 1999-2018: The growing impact of obesity and diabetes

Stefano Ciardullo et al.

Summary: Over the past 20 years, the prevalence of HF in US adults has remained stable, while the prevalence of obesity and diabetes has increased, affecting half of patients with HF. There have been improvements in the control of dyslipidemia and, to a lesser extent, blood pressure, but there is still a significant gap in the guideline-directed use of HF and diabetes medications.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Health benefits of polyphenols: A concise review

Ananya Rana et al.

Summary: Polyphenols produced by plants are highly essential functional foods in our diet. They have diverse chemical structures and play a vital role in protecting the organism and eliminating reactive oxygen species. Polyphenols can be found in tea, chocolate, fruits, and vegetables, and have the potential to positively influence human health by improving lipid profiles, blood pressure, and systemic inflammation. They may also interact with the gut microbiome, leading to therapeutic effects. Therefore, polyphenols are important for human health.

JOURNAL OF FOOD BIOCHEMISTRY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Reactive Oxygen Species: Beyond Their Reactive Behavior

Arnaud Tauffenberger et al.

Summary: Cellular homeostasis is crucial for organism development and aging, with disruption leading to health degradation and death. Reactive oxygen species (ROS) are strongly linked to health decline and neurological disorders, disrupting macromolecules and playing complex roles in cell signaling, particularly in the brain where they impact neuronal survival and synaptic plasticity.

NEUROCHEMICAL RESEARCH (2021)

添加到收藏夹

Review Food Science & Technology

Role of dietary polyphenols on gut microbiota, their metabolites and health benefits

S. Mithul Aravind et al.

Summary: In the past two decades, there has been intensive research on the beneficial health roles of dietary polyphenols in preventing oxidative stress related chronic diseases. As our understanding of the role of gut microbiota advances, the need to examine the prebiotic role of dietary polyphenols has emerged. Further research should focus on the importance of human trials and the links of polyphenols-gut microbiota-nerve-brain to unlock the mechanisms behind the observed benefits of dietary polyphenols.

FOOD RESEARCH INTERNATIONAL (2021)

添加到收藏夹

Editorial Material Medicine, General & Internal

The Leading Causes of Death in the US for 2020

Farida B. Ahmad et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Plant Sciences

A Comprehensive Study of the Antibacterial Activity of Bioactive Juice and Extracts from Pomegranate (Punica granatum L.) Peels and Seeds

Kaja Kupnik et al.

Summary: The pomegranate fruit, known for its health-promoting properties, is increasingly utilized for food purposes, resulting in the generation of biological waste products such as peels. A circular bioeconomy strategy for biowaste holds promise for sustainable development. Extracts from pomegranate peels were found to be rich in secondary metabolites with high antioxidant potential, and showed significant antibacterial efficacy against various strains of bacteria. These findings highlight the great potential of pomegranate in various industries for its antibacterial activity and other health benefits.

PLANTS-BASEL (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Pharmacological Properties of Polyphenols: Bioavailability, Mechanisms of Action, and Biological Effects in In Vitro Studies, Animal Models, and Humans

Kristine Stromsnes et al.

Summary: Drugs are bioactive compounds discovered from plants and animals that interact with molecules in our body, offering pharmacological properties that can prevent and treat diseases. Ingesting molecules like polyphenols through diet can improve health and act as a concomitant treatment against various pathologies.

BIOMEDICINES (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

A comprehensive review on phytochemistry, bioactivity and medicinal value of bioactive compounds of pomegranate (Punica granatum)

Muhammad Modassar Ali Nawaz Ranjha et al.

Summary: Pomegranate is a therapeutic fruit rich in various bioactive compounds, showing antioxidant, anti-hypertensive, cardioprotective, anti-diabetic, and anti-carcinogenic properties, with potential benefits in preventing prostate cancer, reducing colon inflammation, improving renal function, and inhibiting metastatic melanoma growth.

ADVANCES IN TRADITIONAL MEDICINE (2021)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Pomegranate variety and pomegranate plant part, relevance from bioactive point of view: a review

Pablo Melgarejo-Sanchez et al.

Summary: This review provides a comprehensive overview of the bioactivity of pomegranate trees, highlighting the importance of differentiating varieties and plant parts. It aims to identify the most bioactive varieties, potential consumption pathways, and gaps in current research to guide future studies.

BIORESOURCES AND BIOPROCESSING (2021)

添加到收藏夹

Article Chemistry, Applied

Stability of pomegranate peel polyphenols encapsulated in orange juice industry by-product and their incorporation in cookies

Kyriakos Kaderides et al.

FOOD CHEMISTRY (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

Ana Sanches-Silva et al.

PHARMACOLOGICAL RESEARCH (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Early Diagnosis of Myocardial Infarction With Point-of-Care High-Sensitivity Cardiac Troponin I

Jasper Boeddinghaus et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Processing Factors Affecting the Phytochemical and Nutritional Properties of Pomegranate (Punica granatum L.) Peel Waste: A Review

Tandokazi Pamela Magangana et al.

MOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Protection of the myocardium against ischemia/reperfusion injury by punicalagin through an SIRT1-NRF-2-HO-1-dependent mechanism

Li-Ming Yu et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2019)

添加到收藏夹

Article Cell Biology

Comparison of Oxidative Stress Parameters in Heart Failure Patients Depending on Ischaemic or Nonischaemic Aetiology

Ewa Romuk et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

添加到收藏夹

Article Agriculture, Dairy & Animal Science

The 3Rs and Humane Experimental Technique: Implementing Change

Robert C. Hubrecht et al.

ANIMALS (2019)

添加到收藏夹

Review Immunology

Emerging Activators and Regulators of Inflammasomes and Pyroptosis

Yansong Xue et al.

TRENDS IN IMMUNOLOGY (2019)

添加到收藏夹

Article Chemistry, Analytical

Punica granatum Peel Extract Ameliorates Doxorubicin Induced Cardiotoxicity

Imran B. Patel et al.

ANALYTICAL CHEMISTRY LETTERS (2019)

添加到收藏夹

Article Chemistry, Applied

Phenolic compounds as beneficial phytochemicals in pomegranate (Punica granatum L.) peel: A review

Balwinder Singh et al.

FOOD CHEMISTRY (2018)

添加到收藏夹

Review Endocrinology & Metabolism

Metabolic syndrome: an update on diagnostic criteria, pathogenesis, and genetic links

Uzma Zafar et al.

HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (2018)

添加到收藏夹

Review Endocrinology & Metabolism

The Impact of Obesity on the Cardiovascular System

Imre Csige et al.

JOURNAL OF DIABETES RESEARCH (2018)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Novel Insights in the Metabolic Syndrome-induced Oxidative Stress and Inflammation-mediated Atherosclerosis

Johnna F. Varghese et al.

CURRENT CARDIOLOGY REVIEWS (2018)

添加到收藏夹

Article Food Science & Technology

Natural polyphenols: An overview

Munawar Abbas et al.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES (2017)

添加到收藏夹

Review Medical Laboratory Technology

Cardiovascular consequences of metabolic syndrome

Johnathan D. Tune et al.

TRANSLATIONAL RESEARCH (2017)

添加到收藏夹

Article Agriculture, Multidisciplinary

In vitro and in vivo antioxidant activities of three major polyphenolic compounds in pomegranate peel: Ellagic acid, punicalin, and punicalagin

Sun Yu-qing et al.

JOURNAL OF INTEGRATIVE AGRICULTURE (2017)

添加到收藏夹

Review Biochemistry & Molecular Biology

Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly

Francesco Violi et al.

ANTIOXIDANTS & REDOX SIGNALING (2017)

添加到收藏夹

Article Medicine, General & Internal

Effect of Metabolic Syndrome Score, Metabolic Syndrome, and Its Individual Components on the Prevalence and Severity of Angiographic Coronary Artery Disease

Ming-Hui Gui et al.

CHINESE MEDICAL JOURNAL (2017)

添加到收藏夹

Article Integrative & Complementary Medicine

Punicalagin Prevents Hypoxic Pulmonary Hypertension via Anti-Oxidant Effects in Rats

Jingyun Shao et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2016)

添加到收藏夹

Article Environmental Sciences

Pomegranate peel extract attenuates oxidative stress by decreasing coronary angiotensin-converting enzyme (ACE) activity in hypertensive female rats

Roger L. dos Santos et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2016)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Metabolic syndrome update

Scott M. Grundy

TRENDS IN CARDIOVASCULAR MEDICINE (2016)

添加到收藏夹

Article Neurosciences

Microvascular perfusion heterogeneity contributes to peripheral vascular disease in metabolic syndrome

Jefferson C. Frisbee et al.

JOURNAL OF PHYSIOLOGY-LONDON (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dwindling of cardio damaging effect of isoproterenol by Punica granatum L. peel extract involve activation of nitric oxide-mediated Nrf2/ARE signaling pathway and apoptosis inhibition

Mahesh Gupta et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2015)

添加到收藏夹

Article Food Science & Technology

Identification and quantification of major derivatives of ellagic acid and antioxidant properties of thinning and ripe Spanish pomegranates

Nallely Nuncio-Jauregui et al.

JOURNAL OF FUNCTIONAL FOODS (2015)

添加到收藏夹

Article Nutrition & Dietetics

Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats

Thewarid Berkban et al.

NUTRIENTS (2015)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Galectin-3: A Modifiable Risk Factor in Heart Failure

Rudolf A. de Boer et al.

CARDIOVASCULAR DRUGS AND THERAPY (2014)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Clinical relevance of biomarkers in heart failure and cardiorenal syndrome: the role of natriuretic peptides and troponin

Alberto Palazzuoli et al.

HEART FAILURE REVIEWS (2014)

添加到收藏夹

Article Immunology

Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism

Nagla A. El-Shitany et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2014)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Preventive Effects of Ellagic Acid Against Doxorubicin-Induced Cardio-Toxicity in Mice

Ming-cheng Lin et al.

CARDIOVASCULAR TOXICOLOGY (2013)

添加到收藏夹

Article Pharmacology & Pharmacy

Ellagic acid and gingerol, activators of the sarco-endoplasmic reticulum Ca2+-ATPase, ameliorate diabetes mellitus-induced diastolic dysfunction in isolated murine ventricular myocardia

Iyuki Namekata et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2013)

添加到收藏夹

Article Chemistry, Applied

Protective role of Punica granatum (pomegranate) peel and seed oil extracts on diethylnitrosamine and phenobarbital-induced hepatic injury in male rats

Nadia Z. Shaban et al.

FOOD CHEMISTRY (2013)

添加到收藏夹

Article Endocrinology & Metabolism

Ellagic acid inhibits cardiac arrhythmias, hypertrophy and hyperlipidaemia during myocardial infarction in rats

M. Mari Kannan et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2013)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Galectin-3: a novel mediator of heart failure development and progression

Rudolf A. de Boer et al.

EUROPEAN JOURNAL OF HEART FAILURE (2009)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Progression of coronary and mesenteric vascular dysfunction in Zucker obese and Zucker diabetic fatty rats

Christine L. Oltman et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)

添加到收藏夹

Article Agriculture, Multidisciplinary

Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells

LS Adams et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)

添加到收藏夹

Article Medical Laboratory Technology

A new automated colorimetric method for measuring total oxidant status

O Erel

CLINICAL BIOCHEMISTRY (2005)

添加到收藏夹

Review Food Science & Technology

Dietary polyphenols and the prevention of diseases

A Scalbert et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.