期刊
ANTIOXIDANTS
卷 12, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/antiox12030713
关键词
diphenylamine; antioxidant; lipophilicity; NBD; hydrophobicity; RP-TLC
4-Aminodiphenylamino derivatives were studied for their antioxidant and hydrophobic properties, as well as their antimicrobial and antibiofilm activity. Novel derivatives were obtained by reacting the starting material with NBD-chloride. A comprehensive structural analysis was conducted using various techniques, and the hydrophobicity of the compounds was measured experimentally or calculated. The results showed a correlation between the experimental and computed properties. Additionally, some of the synthesized compounds exhibited antimicrobial and antibiofilm activity.
4-Aminodiphenylamino derivatives were investigated for their antioxidant and hydrophobicity character, together with other biological measurements, such as antimicrobial and antibiofilm activity. Among these nine compounds used, we obtained novel derivatives via reaction of the starting material with NBD-chloride. Therefore, we performed a full structural analysis for these compounds, i.e., elemental analysis, IR, UV-Vis, H-1- and C-13-NMR, ESI-MS, X-ray diffraction on single crystal, etc. The hydrophobicity of all the compounds was measured either experimentally using the RP-TLC technique, or via calculation using the fragments method. The other structural characteristics were analyzed, and a correlation between the experimental and computed properties was found. Moreover, the results of the biological evaluation showed that some of the synthesized compounds have antimicrobial and antibiofilm activity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据