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Worldwide Estimation of Parental Acceptance of COVID-19 Vaccine for Their Children: A Systematic Review and Meta-Analysis

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Assessment of caregiver willingness to vaccinate their children against COVID-19 in Saudi Arabia: a cross-sectional study

Mohammed Samannodi et al.

Summary: In Saudi Arabia, an appropriate proportion of parents are willing to vaccinate their children against COVID-19, but there are still some parents who are hesitant, mainly due to poor awareness about the vaccine's effectiveness on children. Raising public awareness of public health is key to gaining public trust in vaccination and the healthcare system.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Biotechnology & Applied Microbiology

Caregivers' intentions to COVID-19 vaccination for their children in China: a cross-sectional survey

Huangyufei Feng et al.

Summary: The study revealed that a high proportion (84.0%) of Chinese caregivers intended to vaccinate their children against COVID-19, especially among those who were willing to be vaccinated themselves. Factors such as older age, lower education level, and perception of vaccine safety and efficacy were associated with caregivers' intention to vaccinate their children. Residence in Hubei province seemed to increase the likelihood of caregivers choosing not to have their children vaccinated. Efforts are needed to address caregivers' concerns about vaccine safety and to encourage their own vaccination before deciding on their children's vaccination.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Biotechnology & Applied Microbiology

Parents' hesitation about getting their children vaccinated against COVID-19 in Japan

Takeshi Yoda et al.

Summary: The study used an internet-based questionnaire survey to determine parents' willingness to get their children vaccinated against COVID-19 in Japan. Significant differences were found in parents' willingness to vaccinate their children across various variables such as gender, age, occupation, income, education background, and parents' own willingness to get vaccinated. Reasons for uncertainty included concerns about potential side effects, safety, and vaccine efficiency.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Biotechnology & Applied Microbiology

Chinese parents' intentions to vaccinate their children against SARS-CoV-2 infection and vaccine preferences

Yulan Lin et al.

Summary: This study investigated Chinese parents' intention to vaccinate their children against SARS-CoV-2 and their preferences for domestically or foreign-made COVID-19 vaccines. Analysis revealed that perceived cost barriers and new vaccine concerns significantly influenced vaccination intent. Vaccine concerns such as efficacy, safety, side effects, and faulty/fake vaccines were important factors in predicting vaccination intent.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Infectious Diseases

Predictors of willingness to get a COVID-19 vaccine in the U.S

Bridget J. Kelly et al.

Summary: Most Americans were willing to get a COVID-19 vaccine, but several vulnerable populations reported low willingness. Public health efforts should address these gaps as national implementation efforts continue. Black respondents were less willing than White respondents to get vaccinated, while Hispanic respondents were more willing. Females, those without insurance, and some younger age groups were also less willing to get vaccinated.

BMC INFECTIOUS DISEASES (2021)

Article Pediatrics

Parents' intention to get vaccinated and to have their child vaccinated against COVID-19: cross-sectional analyses using data from the KUNO-Kids health study

Susanne Brandstetter et al.

Summary: The study reveals considerable COVID-19 vaccination hesitancy among parents in Germany, with factors such as parental confidence in prevention measures and beliefs about policy exaggeration influencing the intention to vaccinate. Comprehensive and tailored communication and education strategies should address these modifiable factors.

EUROPEAN JOURNAL OF PEDIATRICS (2021)

Article Immunology

Anti-COVID Vaccination for Adolescents: A Survey on Determinants of Vaccine Parental Hesitancy

Stefano Zona et al.

Summary: Research found that parents hesitant of anti-COVID vaccination are typically younger, with lower education levels, freelancers, lower household incomes, and have incorrect perceptions of COVID-19 risks and fears of anti-COVID vaccination.

VACCINES (2021)

Article Immunology

Prevalence and Factors Associated with Parents' Non-Intention to Vaccinate Their Children and Adolescents against COVID-19 in Latin America and the Caribbean

Diego Urrunaga-Pastor et al.

Summary: The study aimed to estimate the prevalence and factors associated with parents' non-intention to vaccinate their children and adolescents against COVID-19 in Latin America and the Caribbean. The majority of parents in the region intended to vaccinate their children, with factors such as age, education level, compliance with mitigation strategies, economic status, and existing health conditions influencing parents' decisions.

VACCINES (2021)

Article Immunology

Attitudes of Parents with Regard to Vaccination of Children against COVID-19 in Poland. A Nationwide Online Survey

Mateusz Babicki et al.

Summary: The study examined the attitudes of Polish parents towards vaccinating their children against COVID-19, with results showing that the majority of respondents were females who favored vaccinating their children as soon as possible. Main concerns included the safety and effectiveness of the vaccines, with information mainly obtained from media sources.

VACCINES (2021)

Article Immunology

COVID-19 Vaccine Hesitancy among Parents of Children and Adolescents Living in Brazil

Leonardo Evangelista Bagateli et al.

Summary: The survey in Brazil showed that vaccine hesitancy among caregivers is very low, with even hesitant parents willing to vaccinate their children against COVID-19. This highlights the importance of offering the COVID-19 vaccination to the whole population, including those with uncertainties about other vaccines.

VACCINES (2021)

Article Immunology

Evaluating Rates and Determinants of COVID-19 Vaccine Hesitancy for Adults and Children in the Singapore Population: Strengthening Our Community's Resilience against Threats from Emerging Infections (SOCRATEs) Cohort

Konstadina Griva et al.

Summary: The study found low rates of vaccine hesitancy for adults' own vaccination, but higher rates for children's vaccination. Factors influencing adult hesitancy included living with people in poor health, subjective norm, moral norm, benefits, and necessity of vaccination; while factors influencing parental hesitancy included male gender, lower perceived vaccine benefits, high COVID-19 risk perceptions, vaccination concerns, and necessity beliefs.

VACCINES (2021)

Article Immunology

Association between Adult Vaccine Hesitancy and Parental Acceptance of Childhood COVID-19 Vaccines: A Web-Based Survey in a Northwestern Region in China

A. Kezhong et al.

Summary: The study found a negative correlation between adult vaccine hesitancy and parental acceptance of childhood COVID-19 vaccines, impacting the vaccination rates of other common vaccines for children. Respondents preferred vaccines with lower risks, which were also associated with adult vaccine hesitancy.

VACCINES (2021)

Article Immunology

Intention of Parents to Immunize Children against SARS-CoV-2 in Italy

Luisa Russo et al.

Summary: A study in Italy found that a significant portion of families expressed negative or uncertain attitudes towards vaccinating children aged 12 years and above, as well as those under 12 years. Determinants of vaccination intention included perceived safety and efficacy of vaccines, perceived risk of transmitting infection, and perceived risk of being infected and hospitalized due to COVID-19 for younger children. The study calls for targeted communication strategies focusing on the safety and efficacy of COVID-19 vaccines in children and the dynamics of infection spread across different age groups.

VACCINES (2021)

Article Immunology

Investigating the Influence of Vaccine Literacy, Vaccine Perception and Vaccine Hesitancy on Israeli Parents' Acceptance of the COVID-19 Vaccine for Their Children: A Cross-Sectional Study

Yulia Gendler et al.

Summary: Research in Israel shows that vaccine literacy, perception, hesitancy, and behavior of parents significantly influence their intentions to vaccinate their children against COVID-19. The most crucial factor for parents' decision is their own vaccination status. Providing reliable information about the COVID-19 vaccine is essential in increasing vaccine acceptance.

VACCINES (2021)

Article Dentistry, Oral Surgery & Medicine

Caregiver acceptance of an anticipated COVID-19 vaccination

Ronnie R. Marquez et al.

Summary: This study found that a significant proportion of caregivers are reluctant to have their children vaccinated for COVID-19, but many are willing to follow the recommendation of their physician. Therefore, healthcare professionals play a crucial role in educating the public about the importance of COVID-19 vaccine acceptance.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION (2021)

Article Public, Environmental & Occupational Health

Chinese Parent Intention to Vaccinate Children With Special Diseases Against COVID-19

Xu Wang et al.

Summary: The study found that some parents of children with special diseases are willing to vaccinate their children against COVID-19, and parental willingness to vaccinate is associated with education level and knowledge of the epidemic.

FRONTIERS IN PUBLIC HEALTH (2021)

Review Public, Environmental & Occupational Health

COVID-19 Vaccine Hesitancy in the United States: A Systematic Review

Farah Yasmin et al.

Summary: A systematic review on COVID-19 vaccine uptake in the US revealed varying acceptance rates, with hesitancy particularly high among Black/African Americans and pregnant/breastfeeding women, while lower among males. Efforts need to be made to address these disparities and revise vaccination plans accordingly.

FRONTIERS IN PUBLIC HEALTH (2021)

Article Public, Environmental & Occupational Health

Parental Attitudes and Hesitancy About COVID-19 vs. Routine Childhood Vaccinations: A National Survey

Mohamad-Hani Temsah et al.

Summary: The study found that many parents are hesitant towards the COVID-19 vaccine mainly due to lack of confidence in its effectiveness, safety, and necessity for their children. Parents who rely on official healthcare authority websites for information are more likely to accept childhood COVID-19 vaccination.

FRONTIERS IN PUBLIC HEALTH (2021)

Article Information Science & Library Science

Exploring public perceptions of the COVID-19 vaccine online from a cultural perspective: Semantic network analysis of two social media platforms in the United States and China

Chen Luo et al.

Summary: This study compared public perceptions of the COVID-19 vaccine on social media platforms in the United States and China using semantic network analysis. While both countries shared similar themes related to vaccination policies, priority groups, and challenges, differences were found in individual vaccination experiences, attitudes towards the vaccine, and trust in authorities. These disparities were attributed to cultural differences between the two countries.

TELEMATICS AND INFORMATICS (2021)

Article Immunology

Would Parents Get Their Children Vaccinated Against SARS-CoV-2? Rate and Predictors of Vaccine Hesitancy According to a Survey over 5000 Families from Bologna, Italy

Marco Montalti et al.

Summary: In the study investigating COVID-19 vaccine hesitancy among parents/guardians in Bologna, it was found that a majority were inclined to vaccinate, while hesitancy was higher among female parents/guardians of younger children, with lower education levels, relying on web-based information, and disliking mandatory vaccination policies. These data could help in designing targeted strategies to improve vaccine campaign adherence, especially focusing on web-based information.

VACCINES (2021)

Article Immunology

Vaccine Hesitancy: COVID-19 and Influenza Vaccine Willingness among Parents in Wuxi, China - A Cross-Sectional Study

Qiang Wang et al.

Summary: The study found that parents in China are more hesitant about category B vaccines, with over 40% showing hesitancy and refusal to use COVID-19 and influenza vaccines.

VACCINES (2021)

Article Pediatrics

Parents Willingness to Vaccinate with a COVID-19 Vaccine The Role of Parenthood and Gender

Amelie Altenbuchner et al.

Summary: The study found that parents with minors have a lower willingness to vaccinate with a COVID-19 vaccine compared to those without minors, with fathers showing stronger willingness than mothers. Men are more inclined to have their own children vaccinated with a COVID-19 vaccine compared to women. There is a considerable misrepresentation of vaccination risks and frequent beliefs in vaccination conspiracy theories among parents, especially mothers.

PADIATRIE UND PADOLOGIE (2021)

Article Public, Environmental & Occupational Health

Parental COVID-19 vaccine hesitancy for children: vulnerability in an urban hotspot

Nina L. Alfieri et al.

Summary: The study compared hesitancy towards a future COVID-19 vaccine among different sociodemographic groups in Chicago and Cook County, Illinois, and found that certain groups most severely affected by the pandemic exhibited the highest rates of hesitancy. Parents primarily obtain information about COVID-19 from family, internet, and healthcare providers.

BMC PUBLIC HEALTH (2021)

Article Immunology

COVID-19 vaccine hesitancy and related fears and anxiety

Antonia Bendau et al.

Summary: The study found that COVID-19-related anxiety and health-related fears were significantly associated with higher rates of vaccine acceptance, while fears of social and economic consequences showed the opposite effect. The way people accessed information about the pandemic also influenced their willingness to get vaccinated.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Article Clinical Neurology

Parental psychological distress and attitudes towards COVID-19 vaccination: A cross-sectional survey in Shenzhen, China

Yucheng Xu et al.

Summary: Parental psychological distress is associated with vaccine hesitancy for COVID-19, with parents experiencing psychological distress more likely to hesitate in getting vaccinated themselves, their spouses, and their children. Targeted health education and intervention strategies should be provided to individuals with vaccine hesitancy, especially those susceptible to psychological distress.

JOURNAL OF AFFECTIVE DISORDERS (2021)

Article Health Policy & Services

Parents Intentions to Vaccinate Their Children Against COVID-19

Kristine M. Ruggiero et al.

Summary: Parents' attitudes and behaviors towards the COVID-19 vaccine are influenced by various factors, including concerns about vaccine side effects and safety. Parents who plan to vaccinate their children against the flu are more likely to be willing to vaccinate them against COVID-19 as well.

JOURNAL OF PEDIATRIC HEALTH CARE (2021)

Article Psychiatry

Poison or protection? A mixed methods exploration of Australian parents' COVID-19 vaccination intentions

S. Evans et al.

Summary: The study examined Australian parents' intentions towards COVID-19 vaccination for themselves and their children, finding that 64% of parents intended to vaccinate, 26% were unsure, and 9% intended to decline. Factors such as trust in doctors were associated with vaccination intentions. Qualitative data revealed that many parents had not firmly decided due to concerns about testing, side effects, and long-term outcomes.

JOURNAL OF PSYCHOSOMATIC RESEARCH (2021)

Article Medicine, General & Internal

Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents

Kashif Ali et al.

Summary: The study demonstrates that the mRNA-1273 vaccine has good safety profile in adolescents aged 12 to 17 years, with immune response similar to that in young adults. It also proves the efficacy of the vaccine in preventing Covid-19 in this age group.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Pediatrics

Parents' Intentions and Perceptions About COVID-19 Vaccination for Their Children: Results From a National Survey

Peter G. Szilagyi et al.

Summary: Less than half of US parents are likely to have their children receive a COVID-19 vaccine, with concerns mainly focused on vaccine safety and side effects. Pediatric health care providers play a crucial role in promoting and administering COVID-19 vaccination for children.

PEDIATRICS (2021)

Article Immunology

Parental plans to vaccinate children for COVID-19 in New York city

Chloe A. Teasdale et al.

Summary: The study conducted an online survey of 1,119 parents and caregivers of children aged < 12 years in New York City, finding that a majority of parents planned to vaccinate their children for COVID-19, but a significant proportion expressed hesitancy or resistance. Female and non-Hispanic Black parents were least likely to plan for their children's vaccination, with safety, effectiveness, and perceptions of vaccine necessity as primary reasons for hesitancy. Parents who have or will vaccinate themselves were more likely to plan vaccination for their children as well, highlighting the importance of increasing awareness and education on vaccine safety.

VACCINE (2021)

Article Immunology

The public's role in COVID-19 vaccination: Human-centered recommendations to enhance pandemic vaccine awareness, access, and acceptance in the United States

Monica Schoch-Spana et al.

Summary: In response to the social and economic challenges brought by the COVID-19 pandemic, the importance of vaccine development and uptake is highlighted. A working group in the United States has identified major challenges and opportunities for future COVID-19 vaccination campaigns, emphasizing the need for public understanding, access to, and acceptance of vaccines. The successful implementation of these recommendations is seen as essential for a successful vaccination program.

VACCINE (2021)

Article Infectious Diseases

The impact of the COVID-19 pandemic on parents' behavior toward scheduled pediatric vaccinations in Saudi Arabia

Abdullah Saleh Al-Nafeesah et al.

Summary: This study investigated the impact of the COVID-19 pandemic on parents' behavior towards their children's scheduled vaccinations in Saudi Arabia. The results showed that living in regions with high COVID-19 prevalence and having two or more children were associated with an increased risk of vaccine delay during the pandemic.

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES (2021)

Article Psychiatry

Depression level and coping responses toward the movement control order and its impact on quality of life in the Malaysian community during the COVID-19 pandemic: a web-based cross-sectional study

Anne Yee et al.

Summary: This study investigated the depression level and coping responses towards the lockdown during COVID-19 pandemic in Malaysia and its impact on quality of life. Approximately one in three individuals experienced mild-to-severe depression during the nationwide Movement Control Order (MCO), with younger age, lack of partner, lower income, and living in high-risk areas being significant factors. Those with depression had higher avoidant coping scores and lower religious coping scores, as well as lower scores in each domain of quality of life.

ANNALS OF GENERAL PSYCHIATRY (2021)

Article Biotechnology & Applied Microbiology

Parental acceptability of COVID-19 vaccination for children under the age of 18 years among Chinese doctors and nurses: a cross-sectional online survey

Zixin Wang et al.

Summary: The study found that Chinese healthcare workers who believed in higher vaccine efficacy and longer protection duration, who had confidence in China's ability to prevent another wave of COVID-19 outbreak with vaccines in place, and who were willing to receive a COVID-19 vaccination for themselves were more likely to have their children receive the vaccine. Additionally, those who had higher exposure to information through social media and direct interpersonal communication were more accepting of COVID-19 vaccination for their children, while knowing individuals who experienced serious side effects following vaccination was associated with lower acceptability.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Biotechnology & Applied Microbiology

Willingness and influential factors of parents of 3-6-year-old children to vaccinate their children with the COVID-19 vaccine in China

Xiao Wan et al.

Summary: The study indicates that the majority of Chinese parents of 3-6 year old children are willing to vaccinate their children against COVID-19. Factors such as being female, recognizing their children in high-risk category, actively seeking vaccine-related information, believing in the safety of the vaccine, and understanding the preventive capabilities of the vaccine are associated with higher willingness to vaccinate their children.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Immunology

BNT162b2 COVID-19 Vaccine Hesitancy among Parents of 4023 Young Adolescents (12-15 Years) in Qatar

Sarah Musa et al.

Summary: The study found that key factors influencing parental vaccine hesitancy towards the COVID-19 vaccine for 12-15 year olds include the adolescents' age, parents' nationality, and history of COVID-19 infection. Effective communication strategies targeting parents of younger adolescents, those from Gulf Countries, and parents of adolescents with chronic diseases or previous COVID-19 infection are crucial to increase vaccine uptake and build community trust.

VACCINES (2021)

Article Medicine, General & Internal

The Association Between Risk Perception and COVID-19 Vaccine Hesitancy for Children Among Reproductive Women in China: An Online Survey

Min Du et al.

Summary: The study found that COVID-19 vaccine hesitancy was relatively low among reproductive women in China, but there was still a certain proportion of individuals affected. Vaccine hesitancy was associated with lower perceived susceptibility, increased perceived barriers, and decreased perceived benefits, suggesting that tailored public health measures are needed to enhance perceived susceptibility and benefits while reducing perceived barriers among reproductive women.

FRONTIERS IN MEDICINE (2021)

Article Medicine, General & Internal

Pediatric and Parents' Attitudes Towards COVID-19 Vaccines and Intention to Vaccinate for Children

Soo-Han Choi et al.

Summary: The study found that 76.5% of parents in South Korea intend to get vaccinated against COVID-19, 64.2% intend to have their children vaccinated, but only 49.6% of children responded that they would get vaccinated. Factors such as parents' confidence in the safety of vaccines, willingness to vaccinate themselves, and awareness of the need to vaccinate children were associated with parents' intention to vaccinate their children.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

Article Immunology

Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

John S. Tregoning et al.

Summary: The development and rollout of vaccines have brought hope for controlling the COVID-19 pandemic, with vaccines proving highly effective in preventing disease. However, challenges remain in ensuring equitable access to vaccines globally, as well as lessons to be learned for controlling pandemics in the future.

NATURE REVIEWS IMMUNOLOGY (2021)

Article Public, Environmental & Occupational Health

Willingness to Vaccinate against COVID-19 Might be Systematically Underestimated

Marc Oliver Rieger

Summary: Many individuals initially decline vaccination simply to allow those at higher risk to be vaccinated first. Rephrasing questions and providing additional information can increase willingness to vaccinate. Awareness of herd immunity also boosts vaccination willingness, highlighting the importance of education in promoting vaccine uptake.

ASIAN JOURNAL OF SOCIAL HEALTH AND BEHAVIOR (2021)

Review Microbiology

Vaccine Safety: Myths and Misinformation

Sarah Geoghegan et al.

FRONTIERS IN MICROBIOLOGY (2020)

Review Microbiology

Impact of Vaccines; Health, Economic and Social Perspectives

Charlene M. C. Rodrigues et al.

FRONTIERS IN MICROBIOLOGY (2020)

Article Medicine, General & Internal

Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US

Katherine A. Auger et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Editorial Material Pediatrics

Mental health considerations for children quarantined because of COVID-19

Jia Jia Liu et al.

LANCET CHILD & ADOLESCENT HEALTH (2020)

Article Multidisciplinary Sciences

Economic and social consequences of human mobility restrictions under COVID-19

Giovanni Bonaccorsi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Mathematical & Computational Biology

Assessing the quality of studies in meta-analyses: Advantages and limitations of the Newcastle Ottawa Scale

Claudio Luchini et al.

WORLD JOURNAL OF META-ANALYSIS (2017)

Article Medicine, General & Internal

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

David Moher et al.

ANNALS OF INTERNAL MEDICINE (2009)

Article Public, Environmental & Occupational Health

Vaccination greatly reduces disease, disability, death and inequity worldwide

F. E. Andre et al.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2008)

Article Psychology, Multidisciplinary

Assessing heterogeneity in meta-analysis:: Q statistic or I2 index?

Tania B. Huedo-Medina et al.

PSYCHOLOGICAL METHODS (2006)

Article Education & Educational Research

The bystander effect: A lens for understanding patterns of participation

JM Hudson et al.

JOURNAL OF THE LEARNING SCIENCES (2004)

Article Psychology, Developmental

Maternal and child reports of behavioral compensation in response to safety equipment usage

D DiLillo et al.

JOURNAL OF PEDIATRIC PSYCHOLOGY (2001)