期刊
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
卷 11, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fcell.2023.1145563
关键词
trace elements; acute lymphoblastic leukemia; DNA synthesis; free radical; gene mutation
Trace elements are important substances with low content in the human body and changes in their levels are related to diseases. This paper focuses on their relationship with acute lymphoblastic leukemia (ALL), a malignant blood tumor. Both the trace element levels in ALL patients and the efficacy of different treatment methods are linked to the corresponding trace element changes. It is believed that the abnormal metabolism of trace elements in the body is related to ALL, and this paper aims to provide more information on trace elements for the diagnosis, treatment, and prevention of ALL.
Trace elements are very important substances with low content in the human body. If the content of some trace elements changes, they are also related to diseases. Acute lymphoblastic leukemia (ALL) is a malignant blood tumor, and its relationship with trace elements has also been a concern by scholars. Not only have the trace element levels in ALL patients changed, but the efficacy of different treatment methods has also been linked to the corresponding trace element changes. The characteristics of ALL may be related to the dysregulation of differentiation and proliferation of lymphoid precursor cells. Cell proliferation and differentiation are often affected by changes in DNA levels. However, trace elements are involved in DNA damage and repair mechanisms. In recent years, as an increasing number of studies believe that ALL is related to the abnormal metabolism of trace elements in the body, this paper intends to discuss the research progress on the relationship between trace elements and ALL to provide more information on trace elements for the diagnosis, treatment, and prevention of ALL.
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