相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Group 1 Metabotropic Glutamate Receptors in Neurological and Psychiatric Diseases: Mechanisms and Prospective
Li-Da Su et al.
NEUROSCIENTIST (2022)
Metabotropic Glutamate Receptors As Emerging Targets for the Treatment of Schizophrenia
Shalini Dogra et al.
MOLECULAR PHARMACOLOGY (2022)
The comparative effects of mGlu5 receptor positive allosteric modulators VU0409551 and VU0360172 on cognitive deficits and signalling in the sub-chronic PCP rat model for schizophrenia
Jessica Brown et al.
NEUROPHARMACOLOGY (2022)
The Course of General Cognitive Ability in Individuals With Psychotic Disorders
Katherine Jonas et al.
JAMA PSYCHIATRY (2022)
Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice
Ana Elena Teleuca et al.
LIFE-BASEL (2022)
Impaired discriminative avoidance and increased plasma corticosterone levels induced by vaginal lavage procedure in rats
Marcela Becegato et al.
PHYSIOLOGY & BEHAVIOR (2021)
mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia
Hoau-Yan Wang et al.
MOLECULAR PSYCHIATRY (2020)
Alterations in sleep, sleep spindle, and EEG power in mGluR5 knockout mice
David D. Aguilar et al.
JOURNAL OF NEUROPHYSIOLOGY (2020)
Pharmacological activation of mGlu5 receptors with the positive allosteric modulator VU0360172, modulates thalamic GABAergic transmission
Roberta Celli et al.
NEUROPHARMACOLOGY (2020)
Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia
Ferdinando Nicoletti et al.
FRONTIERS IN PSYCHIATRY (2019)
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system
Luisa Di Menna et al.
NEUROPHARMACOLOGY (2018)
Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies
Adarsh Tripathi et al.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2018)
Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery
Kathy Sengmany et al.
NEUROPHARMACOLOGY (2017)
Metabotropic glutamate receptor, mGlu5, regulates hippocampal synaptic plasticity and is required for tetanisation-triggered changes in theta and gamma oscillations
Arthur Bikbaev et al.
NEUROPHARMACOLOGY (2017)
GABA and schizophrenia: Where we stand and where we need to go
Jill R. Glausier et al.
SCHIZOPHRENIA RESEARCH (2017)
Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus bias
K. Sengmany et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Oxazolidinone-based allosteric modulators, of mGluR5: Defining molecular switches to create a pharmacological tool box
Hong Huang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Dopamine Targeting Drugs for the Treatment of Schizophrenia: Past, Present and Future
Peng Li et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)
Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology
Jo C. Neill et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2016)
An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia
Darrick T. Balu et al.
NEUROPSYCHOPHARMACOLOGY (2016)
Discovery and Preclinical Evaluation of BMS-955829, a Potent Positive Allosteric Modulator of mGluR5
Fukang Yang et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism
Federica Filice et al.
MOLECULAR BRAIN (2016)
Reversal of evoked gamma oscillation deficits is predictive of antipsychotic activity with a unique profile for clozapine
M. R. Hudson et al.
TRANSLATIONAL PSYCHIATRY (2016)
Assessment of disease-related cognitive impairments using the novel object recognition (NOR) task in rodents
Ben Grayson et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Subregional differences in the generation of fast network oscillations in the rat medial prefrontal cortex (mPFC) in vitro
Vasileios Glykos et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders
S. A. Barnes et al.
MOLECULAR PSYCHIATRY (2015)
Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents
Jerri M. Rook et al.
NEURON (2015)
Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism
Hannah A. Hathaway et al.
NEUROPHARMACOLOGY (2015)
Clinical management of negative symptoms of schizophrenia: An update
Evangelia M. Tsapakis et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Converging models of schizophrenia - Network alterations of prefrontal cortex underlying cognitive impairments
Takeshi Sakurai et al.
PROGRESS IN NEUROBIOLOGY (2015)
Acute and chronic effects of NMDA receptor antagonists in rodents, relevance to negative symptoms of schizophrenia: A translational link to humans
Joanna C. Neill et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2014)
Negative symptoms, past and present: A historical perspective and moving to DSM-5
Dolores Malaspina et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2014)
Correction: MGluR5 Mediates the Interaction between Late-LTP, Network Activity, and Learning
Arthur Bikbaev et al.
PLoS One (2014)
OPINION Signalling bias in new drug discovery: detection, quantification and therapeutic impact
Terry Kenakin et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Chronic Ketamine Reduces the Peak Frequency of Gamma Oscillations in Mouse Prefrontal Cortex Ex vivo
James M. McNally et al.
Frontiers in Psychiatry (2013)
A Novel Metabotropic Glutamate Receptor 5 Positive Allosteric Modulator Acts at a Unique Site and Confers Stimulus Bias to mGlu5 Signaling
M. J. Noetzel et al.
MOLECULAR PHARMACOLOGY (2013)
Reduced Natural Oscillatory Frequency of Frontal Thalamocortical Circuits in Schizophrenia
Fabio Ferrarelli et al.
ARCHIVES OF GENERAL PSYCHIATRY (2012)
From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment
Bita Moghaddam et al.
NEUROPSYCHOPHARMACOLOGY (2012)
Ligand Bias at Metabotropic Glutamate 1a Receptors: Molecular Determinants That Distinguish β-Arrestin-Mediated from G Protein-Mediated Signaling
Andrew C. Emery et al.
MOLECULAR PHARMACOLOGY (2012)
Reducing Prefrontal Gamma-Aminobutyric Acid Activity Induces Cognitive, Behavioral, and Dopaminergic Abnormalities That Resemble Schizophrenia
Takeshi Enomoto et al.
BIOLOGICAL PSYCHIATRY (2011)
Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease
Colleen M. Niswender et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
Immunochemical Characterization of Inhibitory Mouse Cortical Neurons: Three Chemically Distinct Classes of Inhibitory Cells
Xiangmin Xu et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2010)
Metabotropic Glutamate Receptor-Mediated Cell Signaling Pathways Are Altered in a Mouse Model of Huntington's Disease
Fabiola M. Ribeiro et al.
JOURNAL OF NEUROSCIENCE (2010)
The Largest Group of Superficial Neocortical GABAergic Interneurons Expresses Ionotropic Serotonin Receptors
SooHyun Lee et al.
JOURNAL OF NEUROSCIENCE (2010)
Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity
Alice L. Rodriguez et al.
MOLECULAR PHARMACOLOGY (2010)
Animal models of cognitive dysfunction and negative symptoms of schizophrenia: Focus on NMDA receptor antagonism
Joanna C. Neill et al.
PHARMACOLOGY & THERAPEUTICS (2010)
Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia
Chantal Schlumberger et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2010)
Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
Jason M. Uslaner et al.
NEUROPHARMACOLOGY (2009)
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia
P. Jeffrey Conn et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
Reduced evoked gamma oscillations in the frontal cortex in schizophrenia patients: A TMS/EEG study
Fabio Ferrarelli et al.
AMERICAN JOURNAL OF PSYCHIATRY (2008)
Relationships between cognitive deficits, symptoms and quality of life in schizophrenia
Kara Savilla et al.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2008)
ADX47273 [S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities
Feng Liu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia
Peter J. Uhlhaas et al.
SCHIZOPHRENIA BULLETIN (2008)
Multiple distinct subtypes of GABAergic neurons in mouse visual cortex identified by triple immunostaining
Yuri Gonchar
Frontiers in Neuroanatomy (2008)
Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat
B. Grayson et al.
BEHAVIOURAL BRAIN RESEARCH (2007)
Age-related changes in transient and oscillatory brain responses to auditory stimulation in healthy adults 19-45 years old
Catherine Poulsen et al.
CEREBRAL CORTEX (2007)
Working memory related gamma oscillations in schizophrenia patients
Canan Basar-Eroglu et al.
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY (2007)
Influence of gender on working and spatial memory in the novel object recognition task in the rat
J. S. Sutcliffe et al.
BEHAVIOURAL BRAIN RESEARCH (2007)
Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks
Marlene Bartos et al.
NATURE REVIEWS NEUROSCIENCE (2007)
The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
Ekrem Dere et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2007)
Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat
Z. Abdul-Monim et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2007)
Ovarian steroids enhance object recognition in naturally cycling and ovariectomized, hormone-primed rats
Alicia A. Walf et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2006)
Glutamate and schizophrenia: Beyond the dopamine hypothesis
Joseph T. Coyle
CELLULAR AND MOLECULAR NEUROBIOLOGY (2006)
Negative symptoms and cognitive deficits: What is the nature of their relationship?
PD Harvey et al.
SCHIZOPHRENIA BULLETIN (2006)
Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness
MO Cunningham et al.
JOURNAL OF NEUROSCIENCE (2006)
Apoptotic mechanisms and the synaptic pathology of schizophrenia
LA Glantz et al.
SCHIZOPHRENIA RESEARCH (2006)
Development of the 40 Hz steady state auditory evoked magnetic field from ages 5 to 52
DC Rojas et al.
CLINICAL NEUROPHYSIOLOGY (2006)
Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes
YQ Zhang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Complementary roles of cholecystokinin- and parvalbumin-expressing GABAergic neurons in hippocampal network oscillations
T Klausberger et al.
JOURNAL OF NEUROSCIENCE (2005)
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
JA Lieberman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Cortical inhibitory neurons and schizophrenia
DA Lewis et al.
NATURE REVIEWS NEUROSCIENCE (2005)
Targeting synapses and myelin in the prevention of schizophrenia
TUW Woo et al.
SCHIZOPHRENIA RESEARCH (2005)
Activation of the phosphoinositide 3-kinase-akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression
LF Hou et al.
JOURNAL OF NEUROSCIENCE (2004)
Calcium dependence of native metabotropic glutamate receptor signaling in central neurons
T Tabata et al.
MOLECULAR NEUROBIOLOGY (2004)
Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro
N Hájos et al.
JOURNAL OF NEUROSCIENCE (2004)
Timing and balance of inhibition enhance the effect of long-term potentiation on cell firing
CP Marder et al.
JOURNAL OF NEUROSCIENCE (2004)
The endophenotype concept in psychiatry: Etymology and strategic intentions
II Gottesman et al.
AMERICAN JOURNAL OF PSYCHIATRY (2003)
Intracellular correlate of EPSP-spike potentiation in CA1 pyramidal neurons is controlled by GABAergic modulation
NP Staff et al.
HIPPOCAMPUS (2003)
Vaginal lavage attenuates cocaine-stimulated activity and establishes place preference in rats
QD Walker et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2002)
Postnatal development of parvalbumin- and GABA transporter-immunoreactive axon terminals in monkey prefrontal cortex
SL Erickson et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2002)