相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mavacamten: First Approval
Susan J. Keam
DRUGS (2022)
Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems
Sampath K. Gollapudi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Applications of Solution NMR in Drug Discovery
Li Shi et al.
MOLECULES (2021)
Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure
John R. Teerlink et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Cardiac myosin-binding protein C interaction with actin is inhibited by compounds identified in a high-throughput fluorescence lifetime screen
Thomas A. Bunch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors
Anthony R. Braun et al.
NPJ PARKINSONS DISEASE (2021)
Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin
Robyn T. Rebbeck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Force Generation by Myosin Motors: A Structural Perspective
Julien Robert-Paganin et al.
CHEMICAL REVIEWS (2020)
The Myosin Family of Mechanoenzymes: From Mechanisms to Therapeutic Approaches
Darshan V. Trivedi et al.
Annual Review of Biochemistry (2020)
Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules That Enhance Ca2+ Transport
Tory M. Schaaf et al.
CELLS (2020)
High-Throughput Screening: today's biochemical and cell-based approaches
Vincent Blay et al.
DRUG DISCOVERY TODAY (2020)
Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness
Mate Gyimesi et al.
CELL (2020)
Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial
Iacopo Olivotto et al.
LANCET (2020)
Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner
Hannah S. Picariello et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Meddling with myosin's mechanobiology in cancer
Alexandra Surcel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin
John A. Rohde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential
Anna A. Rauscher et al.
TRENDS IN BIOCHEMICAL SCIENCES (2018)
Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states
Eric W. Lake et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA
Tory M. Schaaf et al.
SLAS DISCOVERY (2017)
Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke
John A. Rohde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil
Vicente J. Planelles-Herrero et al.
NATURE COMMUNICATIONS (2017)
A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
Eric M. Green et al.
SCIENCE (2016)
High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs Antagonists
Bainan Wu et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)
Direct real-time detection of the structural and biochemical events in the myosin power stroke
Joseph M. Muretta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5
Joseph M. Muretta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structural basis for drug-induced allosteric changes to human β-cardiac myosin motor activity
Donald A. Winkelmann et al.
NATURE COMMUNICATIONS (2015)
Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure
Fady I. Malik et al.
SCIENCE (2011)
Lanthanide Luminescence for Biomedical Analyses and Imaging
Jean-Claude G. Buenzli
CHEMICAL REVIEWS (2010)
High-performance time-resolved fluorescence by direct waveform recording
Joseph M. Muretta et al.
REVIEW OF SCIENTIFIC INSTRUMENTS (2010)
The structural basis of blebbistatin inhibition and specificity for myosin II
JS Allingham et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)