4.2 Article

Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cardiac & Cardiovascular Systems

Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events

Yiyi Zhang et al.

Summary: This study found that cumulative LDL-C and TWA LDL-C during young adulthood and middle age were associated with the risk of incident coronary heart disease (CHD), independent of midlife LDL-C levels. These findings suggest that past levels of LDL-C may inform strategies for primary prevention of CHD and that maintaining optimal LDL-C levels at an earlier age may reduce the lifetime risk of developing atherosclerotic CVD.

JAMA CARDIOLOGY (2021)

Article Cardiac & Cardiovascular Systems

Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia

Mark Trinder et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

Amit V. Khera et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Letter Biochemical Research Methods

The mutation significance cutoff: gene-level thresholds for variant predictions

Yuval Itan et al.

NATURE METHODS (2016)

Article Cardiac & Cardiovascular Systems

Prevalence and management of familial hypercholesterolaemia in patients with acute coronary syndromes

David Nanchen et al.

EUROPEAN HEART JOURNAL (2015)

Article Genetics & Heredity

A general framework for estimating the relative pathogenicity of human genetic variants

Martin Kircher et al.

NATURE GENETICS (2014)

Review Cardiac & Cardiovascular Systems

Homozygous familial hypercholesterolemia: Current perspectives on diagnosis and treatment

Frederick J. Raal et al.

ATHEROSCLEROSIS (2012)