4.5 Article

Curcumin protects against bisphenol A-induced hepatic steatosis by inhibiting cholesterol absorption and synthesis in CD-1 mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Gastroenterology & Hepatology

Global burden of NAFLD and chronic liver disease among adolescents and young adults

James M. Paik et al.

Summary: The study found that the prevalence and mortality rates of chronic liver disease (CLD) have increased among adolescents and young adults aged 15-29, driven primarily by non-alcoholic fatty liver disease (NAFLD). Meanwhile, the proportion of hepatitis B virus (HBV) cases decreased across all age groups, highlighting a shift in the causes of CLD among the younger population.

HEPATOLOGY (2022)

Article Engineering, Environmental

The hazardous threat of Bisphenol A: Toxicity, detection and remediation

Ayon Tarafdar et al.

Summary: Bisphenol A (BPA) is a toxic endocrine disrupting chemical with immunosuppressive activity, disrupting the endogenous hormones and requiring proper detection and remediation methods. More research is needed on integrated remediation technologies and the impact of food processing operations on BPA.

JOURNAL OF HAZARDOUS MATERIALS (2022)

Review Biochemistry & Molecular Biology

Pathogenesis and Therapeutic Strategies Related to Non-Alcoholic Fatty Liver Disease

Tieshan Teng et al.

Summary: Non-alcoholic fatty liver disease (NAFLD) is strongly correlated with obesity, insulin resistance, metabolic syndrome, and genetic components. The disease progression includes non-alcoholic fatty liver, non-alcoholic steatohepatitis, and liver cirrhosis, with different clinical phenotypes. There is currently no FDA-approved medication specifically for treating NAFLD.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Food Science & Technology

Protective effect of the association of curcumin with piperine on prostatic lesions: New perspectives on BPA-induced carcinogenesis

Camila Helena Facina et al.

Summary: Curcumin and piperine can mitigate the detrimental effects of BPA on the prostate gland, reducing nuclear atypia and maintaining the homeostasis of prostate epithelial cells. The protective action of these phytotherapeutic agents is associated with weight loss, anti-inflammatory potential, and control of prostate epithelial cell homeostasis.

FOOD AND CHEMICAL TOXICOLOGY (2021)

Review Environmental Sciences

Multisystemic alterations in humans induced by bisphenol A and phthalates: Experimental, epidemiological and clinical studies reveal the need to change health policies

A. Martinez-Ibarra et al.

Summary: Bisphenol A (BPA) and phthalates, as endocrine-disrupting chemicals, are widely distributed in the environment and can affect cellular proliferation, tissue development, and various physiological processes through interference with hormone synthesis and action. Exposure to these compounds is inevitable and unintentional for humans and living organisms, potentially leading to a wide range of chronic diseases later in life. Monitoring of EDC levels and their impact on human health is crucial for the general population and the healthcare system.

ENVIRONMENTAL POLLUTION (2021)

Article Gastroenterology & Hepatology

FOXA3 induction under endoplasmic reticulum stress contributes to non-alcoholic fatty liver disease

Caizhi Liu et al.

Summary: The study identified FOXA3 as a key bridging molecule connecting ER stress and NAFLD progression, with its deficiency alleviating fatty liver. Increased levels of FOXA3 were found in the livers of obese mice and patients with NAFLD, suggesting FOXA3 as a potential therapeutic target for fatty liver disease.

JOURNAL OF HEPATOLOGY (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

Quantification of Liver Fat Content with CT and MRI: State of the Art

Jitka Starekova et al.

Summary: Hepatic steatosis is defined as pathologically elevated liver fat content and has many underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, with an increasing prevalence among adults and children. Abnormal liver fat accumulation has serious consequences, including cirrhosis, liver failure, and hepatocellular carcinoma.

RADIOLOGY (2021)

Review Nutrition & Dietetics

Curcumin and Biochemical Parameters in Metabolic-Associated Fatty Liver Disease (MAFLD)-A Review

Gracjan Rozanski et al.

Summary: MAFLD, formerly known as NAFLD, is characterized by excess fat accumulation in liver cells and is a major global public health issue. Curcumin supplementation may have potential in treating MAFLD, but further research is needed to confirm its efficacy.

NUTRIENTS (2021)

Review Biotechnology & Applied Microbiology

Curcumin, the golden spice in treating cardiovascular diseases

Hong Li et al.

BIOTECHNOLOGY ADVANCES (2020)

Review Medicine, General & Internal

Disturbances in Cholesterol Homeostasis and Non-alcoholic Fatty Liver Diseases

Pooja Malhotra et al.

FRONTIERS IN MEDICINE (2020)

Article Food Science & Technology

Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects

Haroon Khan et al.

FOOD AND CHEMICAL TOXICOLOGY (2019)

Article Toxicology

Bisphenol A induces cholesterol biosynthesis in HepG2 cells via SREBP-2/HMGCR signaling pathway

Qingrong Li et al.

JOURNAL OF TOXICOLOGICAL SCIENCES (2019)

Article Gastroenterology & Hepatology

Role of bisphenol A as environmental factor in the promotion of non-alcoholic fatty liver disease: in vitro and clinical study

M. Dallio et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2018)

Article Agriculture, Multidisciplinary

Curcumin Protects against Atherosclerosis in Apolipoprotein E-Knockout Mice by Inhibiting Toll-like Receptor 4 Expression

Shanshan Zhang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Article Agriculture, Multidisciplinary

Hypocholesterolemic Activity of Curcumin Is Mediated by Down-regulating the Expression of Niemann-Pick C1-like 1 in Hamsters

Dan Feng et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Review Biochemistry & Molecular Biology

Recent insights on the role of cholesterol in non-alcoholic fatty liver disease

Graciela Arguello et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)

Review Biochemistry & Molecular Biology

Dietary spices as beneficial modulators of lipid profile in conditions of metabolic disorders and diseases

Krishnapura Srinivasan

FOOD & FUNCTION (2013)

Article Gastroenterology & Hepatology

SREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin

Pradeep Kumar et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)

Article Biochemistry & Molecular Biology

HNF1  and SREBP2 are important regulators of NPC1L1 in human liver

C. Pramfalk et al.

JOURNAL OF LIPID RESEARCH (2010)

Article Multidisciplinary Sciences

Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption

SW Altmann et al.

SCIENCE (2004)