4.7 Article

Validation of Enzyme Immunoassays via an Adrenocorticotrophic Stimulation Test for the Non-Invasive Quantification of Stress-Related Hormone Metabolites in Naked Mole-Rats

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Veterinary Sciences

The Effect of Disease and Injury on Faecal Cortisol Metabolites, as an Indicator of Stress in Wild Hospitalised Koalas, Endangered Australian Marsupials

Flavia Santamaria et al.

Summary: Habitat loss, urbanisation and climate change can cause stress in koalas. Non-invasive monitoring of faecal cortisol metabolites (FCMs) can be used to evaluate the impact of stress. The effectiveness of two enzyme immunoassays (EIAs), 50c and cortisol, in measuring FCM values in wild, stressed koalas was tested. Diseased and injured koalas had significantly higher FCM values than clinically healthy control animals as measured by the 50c EIA. Only the 50c EIA detected higher absolute values in males, and also found that females showed a more elevated response to stress manifested by injury and disease. The cortisol EIA was also found unreliable in detecting stress in rehabilitated koalas treated with synthetic glucocorticoids as it cross-reacts with these chemicals.

VETERINARY SCIENCES (2023)

Review Endocrinology & Metabolism

Regulation of stress response on the hypothalamic-pituitary-gonadal axis via gonadotropin-inhibitory hormone

You Lee Son et al.

Summary: Under stressful conditions, the GnIH neuropeptide may play a key role in regulating reproductive function. Different types and durations of stress can modulate the GnIH system, impacting the activity of the HPG axis. GnIH appears to be a potential novel mediator responsible for stress-induced reproductive dysfunction.

FRONTIERS IN NEUROENDOCRINOLOGY (2022)

Article Endocrinology & Metabolism

Patterns of faecal glucocorticoid metabolite levels in captive roan antelope (Hippotragus equinus) in relation to reproductive status and season

Vanessa W. Kamgang et al.

Summary: This study aimed to establish a non-invasive method to monitor stress levels in roan antelope and investigate the relationship between stress levels and reproductive activity and cycles. The results showed that male roan antelope had significantly increased fGCM concentrations during their active reproductive periods, while female roan antelope had significantly higher fGCM concentrations during pregnancy and remained elevated postpartum.

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2022)

Review Biology

Stress in an underground empire

Katarina Medger

Summary: The naked mole-rat and the Damaraland mole-rat live in underground tunnel systems in Africa with most members suppressed from reproduction. Social stress and glucocorticoids may play important roles in reproductive suppression.

BIOLOGY LETTERS (2022)

Article Biochemistry & Molecular Biology

Identification of Koala (Phascolarctos cinereus) Faecal Cortisol Metabolites Using Liquid Chromatography-Mass Spectrometry and Enzyme Immunoassays

Flavia Santamaria et al.

Summary: The koala is an arboreal folivorous marsupial endemic to Australia. Due to threats from anthropogenic activities and climate change, a non-invasive method was used in this study to objectively measure stress in koalas, revealing tetrahydrocortisol as the main faecal cortisol metabolite.

METABOLITES (2021)

Article Endocrinology & Metabolism

Effect of colony disruption and social isolation on naked mole-rat endocrine correlates

Arantxa S. Blecher et al.

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2020)

Article Biochemistry & Molecular Biology

Sex and dose-dependent responses of urinary and faecal glucocorticoid metabolite concentrations following an ACTH challenge in eastern rock sengis (Elephantulus myurus)

Katarina Medger et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2020)

Review Psychology, Biological

Non-invasive measurement of glucocorticoids: Advances and problems

Rupert Palme

PHYSIOLOGY & BEHAVIOR (2019)

Article Endocrinology & Metabolism

Excretion and measurement of corticosterone and testosterone metabolites in bank voles (Myodes glareolus)

Saana Sipari et al.

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2017)

Article Computer Science, Interdisciplinary Applications

Fitting Linear Mixed-Effects Models Using lme4

Douglas Bates et al.

JOURNAL OF STATISTICAL SOFTWARE (2015)

Review Behavioral Sciences

Neural control of chronic stress adaptation

James P. Herman

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2013)

Article Nutrition & Dietetics

Steroid metabolism and excretion in severe anorexia nervosa: effects of refeeding

Wassif S. Wassif et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)

Article Physiology

Sex differences in the excretion of fecal glucocorticoid metabolites in the Syrian hamster

Marie-Odile M. Chelini et al.

JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY (2010)

Article Veterinary Sciences

Non-invasive measurement of adrenocortical activity in male and female rats

M. Lepschy et al.

LABORATORY ANIMALS (2007)

Review Endocrinology & Metabolism

Use of fecal glucocorticold metabolite measures in conservation biology research: considerations for application and interpretation

JJ Millspaugh et al.

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2004)

Review Ecology

Physiological stress in ecology: lessons from biomedical research

LM Romero

TRENDS IN ECOLOGY & EVOLUTION (2004)

Article Veterinary Sciences

Stress and distress: evaluating their impact for the well-being of zoo animals

N Wielebnowski

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2003)

Article Endocrinology & Metabolism

Effects of sex and time of day on metabolism and excretion of corticosterone in urine and feces of mice

C Touma et al.

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2003)

Article Agriculture, Dairy & Animal Science

Hormones as indicators of stress

E Möstl et al.

DOMESTIC ANIMAL ENDOCRINOLOGY (2002)

Article Veterinary Sciences

Measurement of cortisol metabolites in faeces of ruminants

E Mostl et al.

VETERINARY RESEARCH COMMUNICATIONS (2002)