Novel Non-Toxic Highly Antibacterial Chitosan/Fe(III)-Based Nanoparticles That Contain a Deferoxamine-Trojan Horse Ligands: Combined Synthetic and Biological Studies

Review Microbiology

Molecular mechanisms of antibiotic resistance revisited

Elizabeth M. Darby et al.

Summary: Antibiotic resistance is a global health emergency, and understanding the molecular mechanisms that bacteria use to resist antimicrobials is critical. Recent advances in research can aid in developing new antimicrobial therapies.

NATURE REVIEWS MICROBIOLOGY (2023)

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Article Multidisciplinary Sciences

Antimicrobial properties of chitosan from different developmental stages of the bioconverter insect Hermetia illucens

Anna Guarnieri et al.

Summary: Chitin, a biopolymer sourced from insects like Hermetia illucens, can be converted into chitosan, which has intrinsic antimicrobial activity. Studies have shown the antimicrobial capacity of chitosan derived from H. illucens, suggesting potential for its use in the biological field.

SCIENTIFIC REPORTS (2022)

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Article Multidisciplinary Sciences

Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity

Saikat Mitra et al.

Summary: Heavy metals are toxic pollutants that can accumulate in the human body through bioaccumulation. Recent studies have explored treatment options for heavy metal removal, including nanotechnology-based methods, which offer advantages such as a broad linear range, low detection limits, and high sensitivity.

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2022)

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Review Infectious Diseases

Antibiotic Resistance in Bacteria-A Review

Renata Urban-Chmiel et al.

Summary: This article discusses the global problem of multi-drug resistance among bacteria, explores the mechanisms of bacterial resistance, and provides statistical data on the occurrence of drug resistance among selected bacteria in different regions. The article also provides detailed information on the detection of drug resistance genes for specific groups of antibiotics.

ANTIBIOTICS-BASEL (2022)

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Article Engineering, Biomedical

Evaluation of the Antibacterial Properties of Iron Oxide, Polyethylene Glycol, and Gentamicin Conjugated Nanoparticles against Some Multidrug-Resistant Bacteria

Farah M. Abdulsada et al.

Summary: Antibacterial resistance is a global public health issue. A study showed that a combination of iron oxide nanoparticles and gentamicin could effectively treat wound infections caused by Staphylococcus epidermidis, Proteus mirabilis, and Acinetobacter baumannii.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2022)

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Article Engineering, Environmental

Antibacterial Mechanisms of Reduced Iron-Containing Smectite-Illite Clay Minerals

Dongyi Guo et al.

Summary: The antibacterial activity of different clay minerals towards Escherichia coli cells varied based on their layer expandability, with expandable smectite showing the strongest antibacterial activity. This antibacterial effect was attributed to the production of (OH)-O-center dot from the oxidation of structural Fe(II), highlighting the potential of clay minerals as antibacterial agents.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2021)

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Review Environmental Sciences

Antibiotic resistance in the environment: a critical insight on its occurrence, fate, and eco-toxicity

Sakina Bombaywala et al.

Summary: The review highlights the impact of antibiotics on the environment and microbial community, and critically examines the presence of antibiotic residues and resistant genes in different systems. The study identifies areas for further research and outlines global policies to combat antibiotic resistance.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021)

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Article Chemistry, Applied

New water-soluble chitin derivative with high antibacterial properties for potential application in active food coatings

Andreii S. Kritchenkov et al.

Summary: This study presents the synthesis of new chitin derivatives under Green Chemistry conditions using ultrasound-assisted treatment, resulting in water-soluble azido chitin derivatives with high antibacterial activity. These derivatives showed comparable antibacterial properties to commercial antibiotics, and were used for film coating of Ricotta cheese samples to effectively prolong their shelf life.

FOOD CHEMISTRY (2021)

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Review Infectious Diseases

Do Iron Oxide Nanoparticles Have Significant Antibacterial Properties?

Sergey V. Gudkov et al.

Summary: The use of iron oxide nanoparticles (IONPs) shows promise in overcoming antibiotic resistance in bacteria, with studies demonstrating their antimicrobial effects on Gram-negative and Gram-positive bacteria as well as fungi. IONPs also exhibit low toxicity to eukaryotic cells, making them potential antimicrobial agents with high biocompatibility.

ANTIBIOTICS-BASEL (2021)

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Review Biotechnology & Applied Microbiology

Antibiotics: An overview on the environmental occurrence, toxicity, degradation, and removal methods

Qiulian Yang et al.

Summary: This paper provides an overview of the presence of antibiotics in the environment, their toxicity to non-target organisms, and current treatment technologies. Studies have shown that antibiotics are most frequently detected in wastewater, exhibiting toxicity to aquatic organisms. Fluoroquinolones, tetracyclines, and sulfonamides are the most common antibiotics in the environment and can be removed through biotic or abiotic processes.

BIOENGINEERED (2021)

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Review Environmental Sciences