☆ 4.6 Article

Prognostic and recurrent significance of SII in patients with pancreatic head cancer undergoing pancreaticoduodenectomy

FRONTIERS IN ONCOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Gastroenterology & Hepatology

Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment

Liwen Wang et al.

Summary: This study explores the heterogeneity and pro-tumour mechanisms of neutrophils in pancreatic ductal adenocarcinoma (PDAC). The researchers discovered different subpopulations of tumour-associated neutrophils (TANs) associated with prognosis, as well as the glycolytic switch of TANs and the key regulatory factor in polarisation of neutrophils towards a pro-tumour phenotype. Importantly, immunohistochemistry analysis revealed the unfavorable prognostic value of BHLHE40(+) neutrophils in PDAC patients.

GUT (2023)

添加到收藏夹

Editorial Material Gastroenterology & Hepatology

A hypoxic ride for neutrophils in PDAC

Daniela Cerezo-Wallis et al.

GUT (2023)

添加到收藏夹

Article Cell Biology

Development and Validation of an Inflammatory Response-Related Gene Signature for Predicting the Prognosis of Pancreatic Adenocarcinoma

Zu-Liang Deng et al.

Summary: This study identified and constructed a prognostic gene signature using inflammatory response-related genes in pancreatic adenocarcinoma (PAAD). The signature was found to be associated with immune status and sensitivity of cancer cells to anti-tumor drugs, providing potential guidance for the treatment of PAAD.

INFLAMMATION (2022)

添加到收藏夹

Article Oncology

A Paradoxical Role for Regulatory T Cells in the Tumor Microenvironment of Pancreatic Cancer

Thomas Brouwer et al.

Summary: The infiltration of regulatory T cells (Tregs) in pancreatic ductal adenocarcinomas (PDAC) is associated with better overall survival of patients, independent of cytotoxic T cell infiltration and the transcriptomic profiles of their respective tumors.

CANCERS (2022)

添加到收藏夹

Review Oncology

Biological Rationale for Peripheral Blood Cell-Derived Inflammatory Indices and Related Prognostic Scores in Patients with Advanced Non-Small-Cell Lung Cancer

Giuseppe Luigi Banna et al.

Summary: Peripheral blood cell-derived inflammatory indexes and related scores are accurate, reproducible, and cost-effective prognostic tools with clinical and research utility.

CURRENT ONCOLOGY REPORTS (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Identification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis

Xu Wang et al.

Summary: A subset of immunosuppressive P2RX1-negative neutrophils accumulate in the liver metastases of pancreatic ductal adenocarcinoma (PDAC), expressing increased levels of immunosuppressive molecules such as PD-L1 and having enhanced mitochondrial metabolism. The upregulation of the transcription factor Nrf2 in P2RX1-deficient neutrophils is associated with PD-L1 expression and metabolic reprogramming, contributing to the evasion of antitumor immunity by metastatic PDAC tumors.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Review Oncology

Biliary Strictures and Cholangiocarcinoma - Untangling a Diagnostic Conundrum

Alexander Ney et al.

Summary: Cholangiocarcinoma is a rare and highly aggressive biliary tract malignancy that is difficult to diagnose early. Standard serum markers lack sensitivity and specificity, driving the search for novel biomarkers for screening and early detection. However, clinical translation of these biomarkers is slow and further validation in larger patient cohorts is needed.

FRONTIERS IN ONCOLOGY (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors

Alison P. Klein

Summary: Pancreatic cancer is a leading cause of cancer death globally, with significant risk factors including smoking, obesity, diabetes, and genetic factors. Efforts to understand and address these modifiable and inherited risk factors are crucial for early detection and prevention strategies for pancreatic cancer.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Oncology

Pancreatic Adenocarcinoma, Version 2.2021

Margaret A. Tempero et al.

Summary: Pancreatic cancer is the fourth leading cause of cancer-related death in the United States, with a major challenge being advanced disease at diagnosis. While survival rates have not significantly changed, newer treatments, including targeted therapies, offer hope for patients. The manuscript focuses on systemic therapy approaches for locally advanced and metastatic disease.

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2021)

添加到收藏夹

Review Nutrition & Dietetics

Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis

Alex F. Bullock et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2020)

添加到收藏夹

Review Oncology

Immunotherapy for pancreatic cancer: A 2020 update

Dimitrios Schizas et al.

CANCER TREATMENT REVIEWS (2020)

添加到收藏夹

Article Computer Science, Information Systems

The development an artificial intelligence algorithm for early sepsis diagnosis in the intensive care unit

Kuo-Ching Yuan et al.

INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS (2020)

添加到收藏夹

Review Hematology

The Immune Nature of Platelets Revisited

Amal Maouia et al.

TRANSFUSION MEDICINE REVIEWS (2020)

添加到收藏夹

Review Oncology

Neutrophil diversity and plasticity in tumour progression and therapy

Sebastien Jaillon et al.

NATURE REVIEWS CANCER (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Inflammation and Pancreatic Cancer: Focus on Metabolism, Cytokines, and Immunity

Andrea Padoan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

添加到收藏夹

Review Oncology

Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment

Chin-King Looi et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

添加到收藏夹

Review Immunology

The Neutrophil Life Cycle

Andres Hidalgo et al.

TRENDS IN IMMUNOLOGY (2019)

添加到收藏夹

Review Oncology

The Tumor Microenvironment Innately Modulates Cancer Progression

Dominique C. Hinshaw et al.

CANCER RESEARCH (2019)

添加到收藏夹

Article Multidisciplinary Sciences

A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling

Duc-Huy T. Nguyen et al.

SCIENCE ADVANCES (2019)

添加到收藏夹

Article Cell Biology

The role of coagulation and platelets in colon cancer-associated thrombosis

Annachiara Mitrugno et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)

添加到收藏夹

Review Anatomy & Morphology

Development of the human pancreas and its vasculature - An integrated review covering anatomical, embryological, histological, and molecular aspects

Brandon Michael Henry et al.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2019)

添加到收藏夹

Review Oncology

The Platelet Lifeline to Cancer: Challenges and Opportunities

Monika Haemmerle et al.

CANCER CELL (2018)

添加到收藏夹

Review Oncology

Role of platelets and platelet receptors in cancer metastasis

Martin Schlesinger

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

添加到收藏夹

Review Nutrition & Dietetics

Nutrition Implications for Long-Term Survivors of Pancreatic Cancer Surgery

Maria Q. B. Petzel et al.

NUTRITION IN CLINICAL PRACTICE (2017)

添加到收藏夹

Article Oncology

Preoperative Platelet-to-Albumin Ratio Predicts Prognosis of Patients with Pancreatic Ductal Adenocarcinoma After Pancreatic Resection

Yoshihiro Shirai et al.

ANTICANCER RESEARCH (2017)

添加到收藏夹

Article Oncology

Regulatory T cells that co-express RORt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer

Stalin Chellappa et al.

ONCOIMMUNOLOGY (2016)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.