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PLOS ONE (2013)
Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling
Elaine C. Budreck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The effect of transient increases in kynurenic acid and quinolinic acid levels early in life on behavior in adulthood: Implications for schizophrenia
Hannah F. Iaccarino et al.
SCHIZOPHRENIA RESEARCH (2013)
Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder
Lv Wang et al.
MOLECULAR AUTISM (2013)
Kynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice
Xiao-Dan Wang et al.
BRAIN RESEARCH (2012)
Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood
Ana Pocivavsek et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2012)
Glutamatergic Synapse Formation is Promoted by α7-Containing Nicotinic Acetylcholine Receptors
Adrian F. Lozada et al.
JOURNAL OF NEUROSCIENCE (2012)
Risk of Autism Spectrum Disorders in Low Birth Weight and Small for Gestational Age Infants
Katja M. Lampi et al.
JOURNAL OF PEDIATRICS (2012)
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
Hyejung Won et al.
NATURE (2012)
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
Brian J. O'Roak et al.
NATURE (2012)
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
John F. Cryan et al.
NATURE REVIEWS NEUROSCIENCE (2012)
Association with tryptophan hydroxylase 2 gene polymorphisms and autism spectrum disorders in Korean families
So Young Yang et al.
NEUROSCIENCE RESEARCH (2012)
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
Luc Pilotte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders
Brian J. O'Roak et al.
SCIENCE (2012)
Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism
Jill L. Silverman et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Endogenous activation of nAChRs and NMDA receptors contributes to the excitability of CA1 stratum radiatum interneurons in rat hippocampal slices: Effects of kynurenic acid
Manickavasagom Alkondon et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Gastrointestinal flora and gastrointestinal status in children with autism-comparisons to typical children and correlation with autism severity
James B. Adams et al.
BMC GASTROENTEROLOGY (2011)
15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain
Dag H. Yasui et al.
HUMAN MOLECULAR GENETICS (2011)
An Open Label Trial of Donepezil for Enhancement of Rapid Eye Movement Sleep in Young Children with Autism Spectrum Disorders
Ashura Williams Buckley et al.
JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY (2011)
NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1)
Takashi Namba et al.
JOURNAL OF NEUROCHEMISTRY (2011)
IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
Hongen Wei et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Age Dependency of Inhibition of α7 Nicotinic Receptors and Tonically Active N-Methyl-D-aspartate Receptors by Endogenously Produced Kynurenic Acid in the Brain
Manickavasagom Alkondon et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Mutations causing syndromic autism define an axis of synaptic pathophysiology
Benjamin D. Auerbach et al.
NATURE (2011)
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Christiane A. Opitz et al.
NATURE (2011)
Enterotypes of the human gut microbiome
Manimozhiyan Arumugam et al.
NATURE (2011)
Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity
James B. Adams et al.
NUTRITION & METABOLISM (2011)
Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances
Brent L. Williams et al.
PLOS ONE (2011)
Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia
Korrapati V. Sathyasaikumar et al.
SCHIZOPHRENIA BULLETIN (2011)
Deciphering the role of Th17 cells in human disease
Cailin Moira Wilke et al.
TRENDS IN IMMUNOLOGY (2011)
Maternal infection and immune involvement in autism
Paul H. Patterson
TRENDS IN MOLECULAR MEDICINE (2011)
Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia
J. Tarabeux et al.
TRANSLATIONAL PSYCHIATRY (2011)
Circulating and Decidual Th17 Cell Levels in Healthy Pregnancy
Akitoshi Nakashima et al.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2010)
Pyrosequencing study of fecal microflora of autistic and control children
Sydney M. Finegold et al.
ANAEROBE (2010)
Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism
John T. Morgan et al.
BIOLOGICAL PSYCHIATRY (2010)
The Astrocyte-Derived alpha 7 Nicotinic Receptor Antagonist Kynurenic Acid Controls Extracellular Glutamate Levels in the Prefrontal Cortex
Hui-Qiu Wu et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2010)
Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation
Simone Berkel et al.
NATURE GENETICS (2010)
Neurodevelopmental disorders involving genomic imprinting at human chromosome 15q11-q13
Stormy J. Chamberlain et al.
NEUROBIOLOGY OF DISEASE (2010)
Reduction of Endogenous Kynurenic Acid Formation Enhances Extracellular Glutamate, Hippocampal Plasticity, and Cognitive Behavior
Michelle C. Potter et al.
NEUROPSYCHOPHARMACOLOGY (2010)
CORTICAL KYNURENIC ACID BI-DIRECTIONALLY MODULATES PREFRONTAL GLUTAMATE LEVELS AS ASSESSED BY MICRODIALYSIS AND RAPID ELECTROCHEMISTRY
A. Konradsson-Geuken et al.
NEUROSCIENCE (2010)
Cortical Kynurenine Pathway Metabolism: A Novel Target for Cognitive Enhancement in Schizophrenia
Ikwunga Wonodi et al.
SCHIZOPHRENIA BULLETIN (2010)
Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling
Brett C. DiNatale et al.
TOXICOLOGICAL SCIENCES (2010)
Indole as an intercellular signal in microbial communities
Jin-Hyung Lee et al.
FEMS MICROBIOLOGY REVIEWS (2010)
Innate IL-17-producing cells: the sentinels of the immune system
Daniel J. Cua et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release
A. Zmarowski et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Systemic Increase in the Ratio between Foxp3+ and IL-17-Producing CD4+ T Cells in Healthy Pregnancy but Not in Preeclampsia
Brigitte Santner-Nanan et al.
JOURNAL OF IMMUNOLOGY (2009)
Elevated immune response in the brain of autistic patients
Xiaohong Li et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
SPECIFIC INHIBITION OF KYNURENATE SYNTHESIS ENHANCES EXTRACELLULAR DOPAMINE LEVELS IN THE RODENT STRIATUM
L. Amori et al.
NEUROSCIENCE (2009)
Effects of acute tryptophan depletion on memory, attention and executive functions: A systematic review
Daniel Mendelsohn et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2009)
Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function
Edson X. Albuquerque et al.
PHYSIOLOGICAL REVIEWS (2009)
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
William R. Wikoff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice
Masaaki Kanai et al.
MOLECULAR BRAIN (2009)
IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi
Luigina Romani et al.
JOURNAL OF IMMUNOLOGY (2008)
Regulation of spine morphology and spine density by NMDA receptor signaling in vivo
Sila K. Ultanir et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Role of endogenous nicotinic signaling in guiding neuronal development
Zhaoping Liu et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Maternal immune activation alters fetal brain development through interleukin-6
Stephen E. P. Smith et al.
JOURNAL OF NEUROSCIENCE (2007)
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Liang Zhou et al.
NATURE IMMUNOLOGY (2007)
Action-potential-independent GABAergic tone mediated by nicotinic stimulation of immature striatal miniature synaptic transmission
Zhi Liu et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)
Transforming growth factor-β induces development of the TH17 lineage
PR Mangan et al.
NATURE (2006)
Histone hyperacetylation is associated with amelioration of experimental colitis in mice
Rainer Glauben et al.
JOURNAL OF IMMUNOLOGY (2006)
Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease
MT Sapko et al.
EXPERIMENTAL NEUROLOGY (2006)
Immunity, neuroglia and neuroinflammation in autism
CA Pardo et al.
INTERNATIONAL REVIEW OF PSYCHIATRY (2006)
The role of N-methyl-D-asparate receptors in neurogenesis
J Nacher et al.
HIPPOCAMPUS (2006)
Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children
HMRT Parracho et al.
JOURNAL OF MEDICAL MICROBIOLOGY (2005)
Cerebrospinal fluid and serum markers of inflammation in autism
AW Zimmerman et al.
PEDIATRIC NEUROLOGY (2005)
Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum
A Rassoulpour et al.
JOURNAL OF NEUROCHEMISTRY (2005)
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
DH Munn et al.
IMMUNITY (2005)
NMDA receptor currents suppress synapse formation on sprouting axons in vivo
MT Colonnese et al.
JOURNAL OF NEUROSCIENCE (2005)
Neuroglial activation and neuroinflammation in the brain of patients with autism
DL Vargas et al.
ANNALS OF NEUROLOGY (2005)
Cholinergic modulation of microglial activation by α7 nicotinic receptors
RD Shytle et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance
A Honig et al.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2004)
Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: An autoradiographic study in the rat brain
E Tribollet et al.
NEUROSCIENCE (2004)
Real-time PCR quantitation of clostridia in Feces of autistic children
YL Song et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Targeted deletion of the kynurenine aminotransferase II gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via α7 nicotinic receptors in the hippocampus
M Alkondon et al.
JOURNAL OF NEUROSCIENCE (2004)
Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator messenger ribonucleic acids and proteins in rat and human testis
R Schultz et al.
ENDOCRINOLOGY (2003)
Decreased tryptophan catabolism by placental indoleamine 2,3-dioxygenase in preeclampsia
Y Kudo et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2003)
Nicotinic receptor signaling in nonexcitable cells
G Sharma et al.
JOURNAL OF NEUROBIOLOGY (2002)
Gastrointestinal microflora studies in late-onset autism
SM Finegold et al.
CLINICAL INFECTIOUS DISEASES (2002)
The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression:: Physiopathological implications
C Hilmas et al.
JOURNAL OF NEUROSCIENCE (2001)
Short-term benefit from oral vancomycin treatment of regressive-onset autism
RH Sandler et al.
JOURNAL OF CHILD NEUROLOGY (2000)
Developmental regulation of tryptophan hydroxylase messenger RNA expression and enzyme activity in the raphe and its target fields
HB Rind et al.
NEUROSCIENCE (2000)
Perinatal kynurenine pathway metabolism in the normal and asphyctic rat brain
G Ceresoli-Borroni et al.
AMINO ACIDS (2000)