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R. Mesia et al.
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Prianka Singh et al.
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Christiana M. Neophytou et al.
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Daniel E. Johnson et al.
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Michael Bobardt et al.
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Virginia Senkomago et al.
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Barbara Burtness et al.
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C. Safferthal et al.
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Yongsheng Jiang et al.
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R. L. Ferris et al.
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Mona Saraiya et al.
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Stephanie Hehlgans et al.
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Oscar Matzinger et al.
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N. Vanlangenakker et al.
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M. Darding et al.
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Anil K. Chaturvedi et al.
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T. E. Graber et al.
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Patrick K. Ha et al.
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James E. Vince et al.
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Irene Esposito et al.
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Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer:: Pooled analysis in the international head and neck cancer epidemiology consortium
Mia Hashibe et al.
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Allison M. Hunter et al.
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Bipasha Mukherjee et al.
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IM Ward et al.
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SM Srinivasula et al.
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JJ Chai et al.
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CY Du et al.
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