4.6 Article

Pancreatic Cancer Surveillance in Carriers of a Germline Pathogenic Variant in CDKN2A

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Gastroenterology & Hepatology

Long-term yield of pancreatic cancer surveillance in high-risk individuals

Kasper A. Overbeek et al.

Summary: The study aimed to determine the long-term yield of pancreatic cancer surveillance in hereditary high-risk individuals. Results showed substantial diagnostic yield in high-risk mutation carriers, but non-existent in mutation-negative familial pancreatic cancer (FPC) kindreds. Challenges in timely identification of resectable lesions were encountered despite concurrent use of EUS and MRI/MRCP, with the need for more sensitive diagnostic markers, including biomarkers, highlighted.
Article Gastroenterology & Hepatology

Timeline of Development of Pancreatic Cancer and Implications for Successful Early Detection in High-Risk Individuals

Kasper A. Overbeek et al.

Summary: Understanding the timeline and morphologic features of pancreatic cancer progression is crucial for successful imaging-based surveillance. Researchers found that nearly half of high-risk individuals with high-grade dysplasia or pancreatic cancer did not have prior lesions detected by imaging, suggesting the need for more sensitive diagnostic tools.

GASTROENTEROLOGY (2022)

Article Oncology

Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up

Derk C. F. Klatte et al.

Summary: This long-term surveillance study demonstrates a high incidence of pancreatic ductal adenocarcinoma (PDAC) in carriers of a pathogenic variant in the CDKN2A gene. Surveillance in this high-risk population leads to detection of early-stage PDAC with improved resectability and survival.

JOURNAL OF CLINICAL ONCOLOGY (2022)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Review Oncology

Familial Pancreatic Cancer: Current Perspectives

Joan Llach et al.

CANCER MANAGEMENT AND RESEARCH (2020)

Review Pathology

Current Approaches to Pancreatic Cancer Screening

Ankit Chhoda et al.

AMERICAN JOURNAL OF PATHOLOGY (2019)

Article Gastroenterology & Hepatology

European evidence-based guidelines on pancreatic cystic neoplasms

Marco Del Chiaro et al.

Review Gastroenterology & Hepatology

Familial Pancreatic Cancer and the Future of Directed Screening

Sara Welinsky et al.

GUT AND LIVER (2017)

Review Gastroenterology & Hepatology

Screening for pancreatic cancer in familial high-risk individuals: A systematic review

Chao Lu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Article Gastroenterology & Hepatology

Pancreatic ductal adenocarcinoma: Risk factors, screening, and early detection

Andrew E. Becker et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Oncology

Population-Level Analysis of Pancreatic Neuroendocrine Tumors 2 cm or Less in Size

Eric J. Kuo et al.

ANNALS OF SURGICAL ONCOLOGY (2013)

Article Oncology

ATM Mutations in Patients with Hereditary Pancreatic Cancer

Nicholas J. Roberts et al.

CANCER DISCOVERY (2012)

Review Gastroenterology & Hepatology

Review of screening for pancreatic cancer in high risk individuals

Alina Stoita et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

Review Gastroenterology & Hepatology

High Cancer Risk in Peutz-Jeghers Syndrome: A Systematic Review and Surveillance Recommendations

M. G. F. van Lier et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2010)

Article Oncology

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer

Allen S. Ho et al.

TRANSLATIONAL ONCOLOGY (2010)

Article Medicine, General & Internal

Risk of Pancreatic Cancer in Families With Lynch Syndrome

Fay Kastrinos et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Article Oncology

Pancreatic cancer and the FAMMM syndrome

Henry T. Lynch et al.

FAMILIAL CANCER (2008)

Article Radiology, Nuclear Medicine & Medical Imaging

Pancreatic cysts: Depiction on single-shot fast spin-echo MR images

XM Zhang et al.

RADIOLOGY (2002)