Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment

Thymoma and thymic carcinoma are the most common tumors of the anterior mediastinum and a relatively rare type of thoracic cancer. The prerequisite for surgery is clinical staging and operative evaluation, both of which are based on medical imaging. The best strategy for treating a thymic epithelial tumor is surgical resection of the organ and surrounding tissue. Thymectomy modalities vary, including open surgery and minimally invasive surgery, and surgeons have used various innovations to better meet the needs of the procedure; therefore, it is critical to select the appropriate procedure based on the patient's characteristics. Evaluation of resectability is the first step of surgical resection for thymic tumors without distant metastasis. The decision regarding unresectability should be made carefully. During subsequent chemotherapy or chemoradiotherapy, reevaluation of whether an area is resectable or not remains essential. Despite numerous technological advances in the surgical treatment of thymic tumors, several contentious issues remain, including the selection of surgical approaches for difficult cases, the selection of video-assisted thoracoscopic approaches, the evaluation of resectability, minimally invasive surgery for locally advanced thymic tumors, lymphadenectomy in thymic tumors, neoadjuvant therapy for thymic tumors, debulking surgery, and salvage surgery. In solving these problems, the surgeon's judgment, surgical experience, and surgical skills are especially important.

Automated summary

Thymoma and thymic carcinoma are the most common tumors in the anterior mediastinum and a relatively rare type of thoracic cancer. Surgical resection is the best treatment strategy, with various modalities available. The selection of the appropriate procedure should be based on patient characteristics. Evaluation of resectability and careful decision-making are crucial, and reevaluation during subsequent therapy is essential. Several contentious issues remain in the surgical treatment of thymic tumors, requiring the surgeon's judgment, experience, and skills.