期刊
JOURNAL OF CLINICAL MEDICINE
卷 12, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/jcm12051924
关键词
non-suicidal self-injury; stress response; cortisol; DHEA-S; emotional dysregulation; theory of urgency; Ottawa Self Injury Inventory
Non-suicidal self-injury (NSSI) is a significant public health issue that mainly affects female adolescents during puberty. Stress hormones, such as cortisol and DHEA-S, play a role in the development and maintenance of NSSI. Our study found correlations between stress hormones and various factors related to NSSI, suggesting their potential role in the regulation of stress responses and affective states. These findings may have implications for the improvement of treatment and prevention plans for NSSI.
Non-suicidal self-injury (NSSI) is a significant public health issue that particularly affects female adolescents usually emerging during puberty, with a subsequent reduction and even remission in the phenomenon later in life. The dysregulation of the hormonal stress response, particularly cortisol and dehydroepiandrosterone sulfate (DHEA-S), whose levels increase markedly during pubertal adrenarche, has been associated with the development and maintenance of a wide range of emotional disorders. Our study aims to investigate whether different cortisol-DHEA-S response patterns could be associated with the main motivational moderators to engage NSSI as well as with urgency and motivation to stop NSSI in a sample of female adolescents. We found significant correlations between stress hormones and several factors that support and sustain NSSI, specifically: cortisol levels and distressing/upsetting urge (r = 0.39 and a p = 8.94 x 10(-3)) and sensation seeking (r = -0.32 and a p = 0.04), as well as cortisol/DHEA-s ratio and external emotion regulation (r = 0.40 and a p = 0.01) and desire to stop NSSI (r = 0.40 and a p = 0.01). Cortisol and DHEA-S may play a role in NSSI through the regulation of stress responses and affective states. Such results could have implications for the development of new and improved treatment and prevention plans for NSSI.
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