期刊
JOURNAL OF CLINICAL MEDICINE
卷 12, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/jcm12051813
关键词
Merkel cell carcinoma; lymph node; sentinel lymph node biopsy; lymphadenectomy; epidemiology
Merkel cell carcinoma is an aggressive malignant skin tumor with high recurrence and low survival. Lymph nodal metastases are associated with a worse overall prognosis. Factors such as increasing age, tumor size, and truncal location are associated with higher positive lymph node rates.
Merkel cell carcinoma is an aggressive malignant skin tumor with high recurrence and low survival. Lymph nodal metastases are associated with a worse overall prognosis. Our aim was to assess how lymph node procedures and positivity are influenced by demographic, tumor, and treatment characteristics. The Surveillance, Epidemiology and End Results database was searched for all cases of Merkel cell carcinoma of the skin between 2000 and 2019. Univariable analysis was conducted using the chi-squared test with the aim of identifying differences in lymph node procedures and lymph node positivity for each variable. We identified 9182 patients, of which 3139 had sentinel lymph node biopsy/sampling, and 1072 had therapeutic lymph node dissection. Increasing age, increasing tumor size, and truncal location were associated with higher positive lymph node rates.
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