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Review
Microbiology
Hannah E. Davis et al.
Summary: Long COVID is a common and debilitating illness that affects at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, with a wide range of symptoms and impacts on multiple organ systems. There are an estimated 65 million individuals worldwide with long COVID, and the number of cases is increasing daily. Current diagnostic and treatment options are insufficient, and there is a need for clinical trials to address leading hypotheses. Future research should account for biases and testing issues, build on viral-onset research, include marginalized populations, and meaningfully engage patients.
NATURE REVIEWS MICROBIOLOGY
(2023)
Article
Medicine, General & Internal
Marco Ranucci et al.
Summary: According to a prospective cohort study, up to 60% of patients experienced long COVID symptoms, including fatigue, dyspnea, and neuropsychological disturbances, at a mean follow-up of 17 months. The study also found that full vaccination at the time of hospital admission was independently associated with the persistence of physical symptoms, while vaccination and previous neuropsychological symptoms were associated with the persistence of neuropsychological symptoms.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Silvia Bonizzato et al.
Summary: This study aimed to verify the effectiveness of an assessment model for patients with COVID-19, showing qualitative improvements in neuropsychological assessment results. A significant variation in AD-R depression score was found in the three months follow-up evaluation. Evaluating and tracking the impact of COVID-19 on cognitive, psychological, and behavioral domains is crucial for rehabilitation and long-term assistance planning.
NEUROLOGICAL SCIENCES
(2022)
Article
Medicine, General & Internal
Giuseppe Maglietta et al.
Summary: This study investigates the association between factors present during COVID-19 hospitalization and long-term sequelae. The findings suggest that female sex and acute disease severity may serve as independent prognostic factors. Further longitudinal studies with longer follow-up are needed to confirm these results and develop targeted prevention and management strategies for individuals at higher risk for PCS.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Kin Israel Notarte et al.
Summary: This systematic literature review and meta-analysis aimed to identify risk factors for the development of long COVID-19. The study found that advancing age was not associated with long COVID-19, but female sex was a risk factor. Additionally, medical comorbidities such as pulmonary disease, diabetes, obesity, and organ transplantation were also identified as potential risk factors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Carlos Bernal-Utrera et al.
Summary: Telerehabilitation appears to be an effective and safe strategy for recovering from short- and long-term post-COVID-19 sequelae. Mixed protocols of aerobic, respiratory, and low-load strength exercises have shown positive results in improving cardiovascular parameters and physical tests.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Ellen J. Thompson et al.
Summary: The frequency and risk factors of long COVID in community-based individuals are unclear. A study analyzing data from 10 UK population-based studies and electronic health records found wide variation in the frequency of long COVID between studies, but identified some consistent risk factors.
NATURE COMMUNICATIONS
(2022)
Article
Critical Care Medicine
Daniel Munblit et al.
Summary: This international consensus study aims to identify the core outcomes of post-COVID-19 condition, providing a standardized assessment framework for clinical care and global research.
LANCET RESPIRATORY MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Luis Ortega-Paz et al.
Summary: COVID-19 caused by severe acute respiratory syndrome coronavirus-2 can lead to intense inflammatory and prothrombotic states, with cardiovascular implications and an increased risk of thrombotic events. The virus utilizes angiotensin-converting enzyme 2 as a functional receptor, which is highly expressed in the respiratory and cardiovascular systems.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Medicine, General & Internal
Salvatore Corrao et al.
Summary: The immune cell patterns in COVID-19 patients who required hospitalization but not intensive care may have prognostic value, and further cohort studies with larger samples are needed to confirm the weight of prognostic value in predicting outcomes and improving clinical conditions related to immunological changes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Martin Molhave et al.
Summary: This study followed up on discharged COVID-19 patients for 48 weeks and found that 87% of patients reported persistence of at least one symptom, with fatigue and dyspnea being the most frequently reported. Further research is urgently needed to understand the long-term effects and therapeutic options for COVID-19 survivors.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Ani Nalbandian et al.
Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.
Review
Medicine, General & Internal
Shiva Rattan Ambardar et al.
Summary: This paper explores the long-term respiratory complications of severe COVID-19 infection, highlighting potential risks and discussing strategies for prevention.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Fahad M. Iqbal et al.
Summary: This study aimed to investigate the prevalence of clinical characteristics of acute and chronic post-COVID syndrome, finding that fatigue and dyspnoea were the most prevalent symptoms in acute stage, while fatigue and sleep disturbance were the most prevalent symptoms in chronic stage. However, the overall quality of available evidence is poor, with significant risk of bias.
Letter
Medicine, General & Internal
Angelo Carfi et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2020)
Editorial Material
Medicine, General & Internal
Trisha Greenhalgh et al.
BMJ-BRITISH MEDICAL JOURNAL
(2020)
Editorial Material
Infectious Diseases
Dana Yelin et al.
LANCET INFECTIOUS DISEASES
(2020)
