☆ 4.7 Review

Stage IV Colorectal Cancer Management and Treatment

JOURNAL OF CLINICAL MEDICINE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Molecular residual disease and efficacy of adjuvant chemotherapy in patients with colorectal cancer

Daisuke Kotani et al.

Summary: Circulating tumor DNA (ctDNA) analysis can help with risk stratification and treatment decisions for patients with resectable colorectal cancer (CRC). The study found that postsurgical ctDNA positivity was associated with higher recurrence risk and was the most significant prognostic factor for patients with stage II or III CRC. Furthermore, ctDNA positivity identified patients who derived benefit from adjuvant chemotherapy.

NATURE MEDICINE (2023)

添加到收藏夹

Review Medicine, General & Internal

Development of the Peritoneal Metastasis: A Review of Back-Grounds, Mechanisms, Treatments and Prospects

Kaijie Ren et al.

Summary: Peritoneal metastasis is a malignant disease originating from gastrointestinal and gynecological carcinomas, causing long-term suffering in patients. New molecular mechanisms and treatments have been proposed, but more research is needed due to the uncertainty of influencing factors and the lack of a standardized procedure. We aim to summarize the backgrounds, mechanisms, and treatments in this area and identify limitations or new aspects for treatments.

JOURNAL OF CLINICAL MEDICINE (2023)

添加到收藏夹

Article Oncology

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

A. Cervantes et al.

ANNALS OF ONCOLOGY (2023)

添加到收藏夹

Article Gastroenterology & Hepatology

Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN

Eileen Morgan et al.

Summary: Colorectal cancer is the third most common cancer worldwide, with the highest incidence rates in Australia/New Zealand and Europe, and the lowest rates in Africa and Southern Asia. The burden of colorectal cancer is projected to increase by 2040, with the majority of cases predicted to occur in high HDI countries.

GUT (2023)

添加到收藏夹

Article Oncology

Treatment of Metastatic Colorectal Cancer: ASCO Guideline

Van K. Morris et al.

Summary: The purpose of this study is to develop treatment recommendations for patients with metastatic colorectal cancer (mCRC). An Expert Panel convened by ASCO conducted a systematic review of relevant studies and developed recommendations for clinical practice. Based on the inclusion criteria, five systematic reviews and ten randomized controlled trials were included in the analysis. The recommendations include offering doublet chemotherapy or triplet therapy to previously untreated mCRC patients who are initially unresectable, based on studies of chemotherapy combined with anti-vascular endothelial growth factor antibodies. Pembrolizumab is recommended for first-line treatment of mCRC patients with microsatellite instability-high or deficient mismatch repair tumors. Chemotherapy and anti-epidermal growth factor receptor therapy are recommended for microsatellite stable or proficient mismatch repair left-sided treatment-naive RAS wild-type mCRC, while chemotherapy and anti-vascular endothelial growth factor therapy are recommended for microsatellite stable or proficient mismatch repair RAS wild-type right-sided mCRC. Encorafenib plus cetuximab is recommended for previously treated BRAF V600E-mutant mCRC patients who have progressed after one previous line of therapy. Other recommendations are provided for patients with colorectal peritoneal metastases, liver metastases, and candidates for potentially curative resection of liver metastases. Multidisciplinary team management and shared decision making are also recommended.

JOURNAL OF CLINICAL ONCOLOGY (2023)

添加到收藏夹

Review Oncology

Two stage hepatectomy (TSH) versus ALPPS for initially unresectable colorectal liver metastases: A systematic review and meta-analysis

Tamara Diaz Vico et al.

Summary: This systematic review and meta-analysis compared perioperative and oncological outcomes between Two Stage Hepatectomy (TSH) and Associating Liver Partition and Portal Vein Ligation for staged hepatectomy (ALPPS) in patients with initially unresectable colorectal liver metastases (CRLM). The results showed that ALPPS had higher postoperative major complications, higher completion of hepatectomy rates, and higher R0 resection rates compared to TSH. However, there were no significant differences in overall survival (OS) and disease-free survival (DFS) between the two groups.

EJSO (2023)

添加到收藏夹

Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Selected stage IV rectal cancer patients managed by the watch-and-wait approach after pelvic radiotherapy: a good alternative to total mesorectal excision surgery?

Petra A. Custers et al.

Summary: This study aimed to assess the clinical and oncological outcomes of stage IV rectal cancer patients who underwent the watch-and-wait approach following radiotherapy. The results showed that the watch-and-wait approach can help avoid total mesorectal excision and permanent colostomy in the majority of patients, despite a relatively high regrowth rate.

COLORECTAL DISEASE (2022)

添加到收藏夹

Article Oncology

First-Line Nivolumab Plus Low-Dose Ipilimumab for Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Phase II CheckMate 142 Study

Heinz-Josef Lenz et al.

Summary: Nivolumab plus low-dose ipilimumab demonstrated robust and durable clinical benefit and was well tolerated as a first-line treatment for MSI-H/dMMR mCRC.

JOURNAL OF CLINICAL ONCOLOGY (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Surgical Therapy in Patients with Colorectal Liver Metastases

Jan Keck et al.

Summary: Surgical options for colorectal liver metastases (CRLM) are limited by the location of the metastases and their proximity to major vessels and intrahepatic bile ducts. Lesions in the periphery can be excised with a parenchymal-sparing fashion, while anatomical resections based on segmental boundaries are performed in other cases.

DIGESTION (2022)

添加到收藏夹

Article Oncology

Panitumumab Plus Fluorouracil and Folinic Acid Versus Fluorouracil and Folinic Acid Alone as Maintenance Therapy in RAS Wild-Type Metastatic Colorectal Cancer: The Randomized PANAMA Trial (AIO KRK 0212)

Dominik Paul Modest et al.

Summary: The PANAMA trial investigated the efficacy of adding panitumumab to maintenance therapy in patients with RAS wild-type metastatic colorectal cancer, and found that combining panitumumab with fluorouracil and folinic acid could significantly improve progression-free survival in these patients.

JOURNAL OF CLINICAL ONCOLOGY (2022)

添加到收藏夹

Article Health Care Sciences & Services

Eastern Cooperative Oncology Group Performance Status #434

Anne-Marie Mischel et al.

JOURNAL OF PALLIATIVE MEDICINE (2022)

添加到收藏夹

Article Oncology

Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study

Luis A. Diaz et al.

Summary: The final overall survival analysis of the KEYNOTE-177 study showed that while pembrolizumab continued to demonstrate durable antitumor activity and fewer treatment-related adverse events compared to chemotherapy in patients with microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer, there was no statistically significant difference in overall survival between the two treatment groups.

LANCET ONCOLOGY (2022)

添加到收藏夹

Review Surgery

Effect of radical lymphadenectomy in colorectal cancer with para-aortic lymph node metastasis: a systematic review and meta-analysis

Pengyue Zhao et al.

Summary: This systematic review and meta-analysis found that radical lymphadenectomy can significantly improve overall survival in patients with colorectal cancer and para-aortic lymph node metastasis. It also showed that radical lymphadenectomy does not increase the risk of postoperative complications.

BMC SURGERY (2022)

添加到收藏夹

Review Oncology

Efficacy and safety of different options for liver regeneration of future liver remnant in patients with liver malignancies: a systematic review and network meta-analysis

Fengming Yi et al.

Summary: This study compared the efficacy and safety of different surgical techniques for liver malignancies using network meta-analysis. The results showed that Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) had the highest increase in standardized future liver remnant (sFLR), shorter time to hepatectomy, and higher resection rate. However, ALPPS also had a higher complication rate and 90-day mortality compared to other treatments.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

Role Of Ovarian Metastases In Colorectal Cancer (ROMIC): a Dutch study protocol to evaluate the effect of prophylactic salpingo-oophorectomy in postmenopausal women

R. Van der Meer et al.

Summary: The study aims to evaluate the effect of prophylactic salpingo-oophorectomy (PSO) in postmenopausal patients with colorectal cancer (CRC). Information bulletins and decision guides will be implemented in several Dutch hospitals to collect prospective data and estimate the incidence of ovarian metastases (OM) and primary ovarian cancer. The expected results will provide valuable information on the necessity of PSO in postmenopausal CRC patients.

BMC WOMENS HEALTH (2022)

添加到收藏夹

Article Oncology

Modified FOLFOXIRI plus panitumumab (mFOLFOXIRI/PAN) versus mFOLFOX6/PAN as initial treatment of patients with unresectable RAS and BRAF wild-type metastatic colorectal cancer (mCRC): Results of the phase III randomized TRIPLETE study by GONO.

Chiara Cremolini et al.

JOURNAL OF CLINICAL ONCOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Survival Outcomes after Elective or Emergency Surgery for Synchronous Stage IV Colorectal Cancer

Ji-Yeon Mun et al.

Summary: Patients with stage IV colorectal cancer who have not undergone primary tumor resection are at risk of sudden medical emergencies. This study compared the survival outcomes of elective and emergency surgery in this population and found that elective surgery was associated with significantly better 2-year overall survival.

BIOMEDICINES (2022)

添加到收藏夹

Review Surgery

Synchronous liver and peritoneal metastases from colorectal cancer: Is cytoreductive surgery and hyperthermic intraperitoneal chemotherapy combined with liver resection a feasible option?

Sara Di Carlo et al.

Summary: This study reviewed the surgical and survival outcomes of an extensive surgical approach including cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) and liver resection (LR) for patients with colorectal liver and peritoneal metastases. The results showed higher morbidity and mortality rates in patients who underwent this extensive surgical approach compared to those who only underwent CRS and HIPEC. Additionally, the survival rates were worse for patients in the former group than the latter group. Therefore, a more accurate selection of patients and more restrictive surgical indications may improve outcomes in this subgroup of patients with limited curative options.

FRONTIERS IN SURGERY (2022)

添加到收藏夹

Review Public, Environmental & Occupational Health

Cost of treating metastatic colorectal cancer: a systematic review

N. Bhimani et al.

Summary: This systematic review examines the direct cost of treating metastatic colorectal cancer and highlights the significant economic burden it places on healthcare systems. The review emphasizes the need for future research to define cost components and examine the relationship between spending, overall survival, and quality of life.

PUBLIC HEALTH (2022)

添加到收藏夹

Article Oncology

Treatment With Stereotactic Ablative Radiotherapy for Up to 5 Oligometastases in Patients With Cancer Primary Toxic Effect Results of the Nonrandomized Phase 2 SABR-5 Clinical Trial

Robert Olson et al.

Summary: This study confirms that the incidence of high-grade toxic effects in the large cohort of patients receiving SABR for oligometastases is less than 5%. The lower rates of toxic effects compared to previous studies may support further enrollment in randomized phase 3 clinical trials.

JAMA ONCOLOGY (2022)

添加到收藏夹

Article Medicine, General & Internal

Incidence and Survival in Synchronous and Metachronous Liver Metastases From Colorectal Cancer

Noemi Reboux et al.

Summary: This study analyzed the temporal patterns and outcomes of synchronous and metachronous liver metastases from colorectal cancer using a population-based cohort study in France. The incidence of synchronous liver metastases remained relatively stable over time, while the probability of developing metachronous liver metastases decreased. Survival rates were significantly higher for patients with metachronous liver metastases compared to synchronous metastases. The differences in the epidemiological features of synchronous and metachronous liver metastases may have implications for future clinical trials.

JAMA NETWORK OPEN (2022)

添加到收藏夹

Review Gastroenterology & Hepatology

Recent Advance in the Surgical Treatment of Metastatic Colorectal

Eun Jung Park et al.

Summary: Stage IV colorectal cancer (CRC) presents heterogeneous characteristics in tumor extent and biology, making treatment challenging. Tailored surgical treatments and multidisciplinary approaches may improve survival and the quality of life for patients with metastatic CRC.

JOURNAL OF THE ANUS RECTUM AND COLON (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Safety and long-term prognosis of simultaneous versus staged resection in synchronous colorectal cancer with liver metastasis: a systematic review and meta-analysis

Shi-hao Wang et al.

Summary: This meta-analysis compared the safety and prognosis of simultaneous and staged resection of synchronous colorectal liver metastases (SCLMs). The results showed that simultaneous resection had similar complications and survival outcomes compared to staged resection, but had lower intraoperative blood loss and shorter hospital stay. The study suggests that simultaneous resection can be considered as the first choice for resectable SCLM patients.

EUROPEAN JOURNAL OF MEDICAL RESEARCH (2022)

添加到收藏夹

Article Oncology

Surgery combined with intra-operative microwaves ablation for the management of colorectal cancer liver metastasis: A case-matched analysis and evaluation of recurrences

Simone Guadagni et al.

Summary: Hepatic resection is the only chance of cure for a subgroup of patients with colorectal cancer liver metastasis. Intra-operative microwaves ablation combined with hepatic resection does not seem to have significant advantages over surgery alone in terms of oncologic outcomes for patients undergoing metastases resection with radical intent.

FRONTIERS IN ONCOLOGY (2022)

添加到收藏夹

Article Oncology

An Evidence-Based Guideline for Surveillance of Patients after Curative Treatment for Colon and Rectal Cancer

Erin Kennedy et al.

Summary: Regular monitoring and surveillance are recommended for patients with Stage I-III colon cancer, including medical history, physical examination, and CT imaging. Current recommendations lack sufficient evidence to support similar surveillance regimens for patients with rectal cancer, Stage IV colon cancer, and elderly patients.

CURRENT ONCOLOGY (2022)

添加到收藏夹

Article Surgery

Simultaneous Versus Delayed Resection for Initially Resectable Synchronous Colorectal Cancer Liver Metastases A Prospective, Open-label, Randomized, Controlled Trial

Karim Boudjema et al.

Summary: This study compared simultaneous resection and delayed resection of synchronous colorectal cancer liver metastases, finding no significant difference in the rate of major complications between the two groups. However, delayed resection tended to impair overall survival.

ANNALS OF SURGERY (2021)

添加到收藏夹

Article Oncology

Survival outcome and prognostic factors for colorectal cancer with synchronous bone metastasis: a population-based study

Xiaofen Li et al.

Summary: The study investigated the survival outcomes and prognostic factors of patients with synchronous bone metastatic colorectal cancer, identifying seven independent prognostic factors including histological type, differentiation grade, T stage of primary tumor, CEA level, systemic chemotherapy, combined with liver metastasis and combined with lung metastasis. A novel nomogram based on these factors showed good performance in predicting survival outcomes in both internal and external validation.

CLINICAL & EXPERIMENTAL METASTASIS (2021)

添加到收藏夹

Article Oncology

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial

Francois Quenet et al.

Summary: This study aimed to evaluate the specific benefit of adding hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery compared with receiving cytoreductive surgery alone in patients with colorectal peritoneal metastases. The results showed no significant overall survival benefit after adding HIPEC, with more frequent postoperative late complications, suggesting that cytoreductive surgery alone should be prioritized as a treatment strategy.

LANCET ONCOLOGY (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surveillance and Survivorship Care of Patients After Curative Treatment of Colon and Rectal Cancer

Karin M. Hardiman et al.

DISEASES OF THE COLON & RECTUM (2021)

添加到收藏夹

Review Medicine, General & Internal

Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review

Leah H. Biller et al.

Summary: Colorectal cancer is the third most common cause of cancer mortality worldwide. For patients diagnosed with metastatic colorectal cancer, approximately 70% to 75% can survive beyond 1 year. Tailoring treatments based on the molecular and pathologic features of the tumor has shown to improve overall survival rates.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Oncology

Encorafenib Plus Cetuximab as a New Standard of Care for Previously Treated BRAF V600E-Mutant Metastatic Colorectal Cancer: Updated Survival Results and Subgroup Analyses from the BEACON Study

Josep Tabernero et al.

Summary: The study evaluated different treatment regimens for patients with BRAF V600E-mutant metastatic colorectal cancer, showing that encorafenib plus cetuximab improved overall survival, objective response rate, and progression-free survival compared to standard chemotherapy.

JOURNAL OF CLINICAL ONCOLOGY (2021)

添加到收藏夹

Review Oncology

The Role of Cancer Stem Cells in Colorectal Cancer: From the Basics to Novel Clinical Trials

Celine Hervieu et al.

Summary: This review highlights the significance of colorectal cancer stem cells (CCSCs) in tumor growth, therapy resistance, and metastasis, while also discussing the methods for isolating and characterizing them, as well as ongoing clinical trials targeting CCSCs. The complexity of studying CSCs in CRC poses challenges in developing effective treatments that address therapy resistance and tumor initiation.

CANCERS (2021)

添加到收藏夹

Article Oncology

Is There a Role for Perioperative Pelvic Radiotherapy in Surgically Resected Stage IV Rectal Cancer? A Propensity Score-matched Analysis

Jeanny Kwon et al.

Summary: This study showed that perioperative pelvic radiotherapy significantly improved overall survival rates in stage IV rectal cancer patients, especially in those without lung metastases. A web-based calculator was successfully developed to provide individualized estimates of survival benefit with the addition of radiotherapy for these patients.

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2021)

添加到收藏夹

Review Gastroenterology & Hepatology

Current strategies to induce liver remnant hypertrophy before major liver resection

Celeste Del Basso et al.

Summary: Hepatic resection is the preferred treatment for liver tumors, but it carries the risk of post-operative liver failure. Clinical judgement is essential in selecting suitable patients for surgery and implementing effective pre-operative strategies to ensure an adequate future liver remnant.

WORLD JOURNAL OF HEPATOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colonic Volvulus and Acute Colonic Pseudo-Obstruction

Karim Alavi et al.

DISEASES OF THE COLON & RECTUM (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Metabolic Reprogramming of Colorectal Cancer Cells and the Microenvironment: Implication for Therapy

Miljana Nenkov et al.

Summary: Colorectal carcinoma is a common cancer characterized by metabolic reprogramming that provides tumor cells with energy and nutrients for malignant growth. The metabolic crosstalk between tumor cells, the tumor microenvironment, and gut microbiota facilitates the development and therapy resistance of colorectal carcinoma.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Oncology

The clinicopathological characteristics, prognosis, and CT features of ovary metastasis from colorectal carcinoma

Zeyang Chen et al.

Summary: In this study, the clinical manifestations, pathological characteristics, and developments of patients with ovary metastasis from colorectal carcinoma (OM-CRC) were investigated through CT results. The research found that characteristics such as a well-defined ovarian mass, predominantly cystic, presence of peritoneal implantation, and absence of lymphadenopathy were common in OM-CRC cases. Additionally, synchronous metastasis and R2 resection during cytoreductive surgery were negatively associated with the prognosis of OM-CRC, with R2 resection being identified as the only independent predictor of overall survival and progression-free survival rates.

TRANSLATIONAL CANCER RESEARCH (2021)

添加到收藏夹

Review Oncology

Strategies to tackle RAS-mutated metastatic colorectal cancer

G. Patelli et al.

Summary: RAS oncogene is commonly mutated in cancer, particularly in metastatic colorectal cancer (mCRC), leading to poor prognosis and resistance to certain treatments. Recent advancements in specific KRAS(G12C) inhibitors have renewed interest in targeting this biomarker. Direct KRAS(G12C) inhibition is emerging as a promising strategy in mCRC and other solid malignancies, showing potential for improved treatment efficacy in the future.

ESMO OPEN (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Diagnostic and Prognostic Value of CEA and CA19-9 in Colorectal Cancer

Leilani Lakemeyer et al.

Summary: Measuring CEA and CA19-9 preoperatively in colorectal cancer patients is a reasonable method to predict the 5-year survival and tumor recurrence.

DISEASES (2021)

添加到收藏夹

Article Surgery

Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases

Svein Dueland et al.

ANNALS OF SURGERY (2020)

添加到收藏夹

Article Oncology

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer

Yojiro Hashiguchi et al.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2020)

添加到收藏夹

Article Oncology

The Impact of Primary Tumor Location in Synchronous Metastatic Colorectal Cancer: Differences in Metastatic Sites and Survival

Nelleke P. M. Brouwer et al.

ANNALS OF SURGICAL ONCOLOGY (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Prognostic factors influencing survival in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for isolated colorectal peritoneal metastases: a systematic review and meta-analysis

V. Narasimhan et al.

COLORECTAL DISEASE (2020)

添加到收藏夹

Review Oncology

Surgical treatment of stage IV colorectal cancer with synchronous liver metastases: A systematic review and network meta-analysis

Mohammad Ghiasloo et al.

EJSO (2020)

添加到收藏夹

Article Oncology

Treatment strategies and overall survival for incurable metastatic colorectal cancer - A EURECCA international comparison including 21,196 patients from the Netherlands and Norway

A. J. Breugom et al.

EJSO (2020)

添加到收藏夹

Article Surgery

Aggressive Multimodal Treatment and Metastatic Colorectal Cancer Survival

George Q. Zhang et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2020)

添加到收藏夹

Article Oncology

Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials

David S. Hong et al.

LANCET ONCOLOGY (2020)

添加到收藏夹

Article Oncology

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials

Robert C. Doebele et al.

LANCET ONCOLOGY (2020)

添加到收藏夹

Review Oncology

The Role of Maintenance Strategies in Metastatic Colorectal Cancer A Systematic Review and Network Meta-analysis of Randomized Clinical Trials

Mohamad Bassam Sonbol et al.

JAMA ONCOLOGY (2020)

添加到收藏夹

Article Oncology

A Randomized Phase II Study of Perioperative Chemotherapy Plus Bevacizumab Versus Postoperative Chemotherapy Plus Bevacizumab in Patients With Upfront Resectable Hepatic Colorectal Metastases

You Jin Chun et al.

CLINICAL COLORECTAL CANCER (2020)

添加到收藏夹

Article Oncology

Epidemiology of liver metastases

Samantha R. Horn et al.

CANCER EPIDEMIOLOGY (2020)

添加到收藏夹

Article Oncology

ALPPS versus two-stage hepatectomy for colorectal liver metastases--a comparative retrospective cohort study

Jan Bednarsch et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2020)

添加到收藏夹

Article Oncology

Individual Patient Data Meta-Analysis of FOLFOXIRI Plus Bevacizumab Versus Doublets Plus Bevacizumab as Initial Therapy of Unresectable Metastatic Colorectal Cancer

Chiara Cremolini et al.

JOURNAL OF CLINICAL ONCOLOGY (2020)

添加到收藏夹

Review Oncology

Conventional Two-Stage Hepatectomy or Associating Liver Partitioning and Portal Vein Ligation for Staged Hepatectomy for Colorectal Liver Metastases? A Systematic Review and Meta-Analysis

Liang Zhang et al.

FRONTIERS IN ONCOLOGY (2020)

添加到收藏夹

Article Medicine, General & Internal

Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer

T. Andre et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Article Oncology

Canadian guidelines on the management of colorectal peritoneal metastases

A. Brind'Amour et al.

CURRENT ONCOLOGY (2020)

添加到收藏夹

Article Surgery

Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population-based study

V. Vayrynen et al.

BJS OPEN (2020)

添加到收藏夹

Review Oncology

Clinical outcomes of curative treatment for colorectal liver metastases combined with cytoreductive surgery and intraperitoneal chemotherapy for peritoneal metastases: a systematic review and meta-analysis of current evidence

Yifeng Zou et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2020)

添加到收藏夹

Article Pathology

Molecular characterization of cancers with NTRK gene fusions

Zoran Gatalica et al.

MODERN PATHOLOGY (2019)

添加到收藏夹

Article Surgery

Endovascular Treatment of Peripheral Vascular Blowout Syndrome in End-Stage Malignancies

Fabio Corvino et al.

ANNALS OF VASCULAR SURGERY (2019)

添加到收藏夹

Article Oncology

Survival Outcomes After Surgical Management of the Primary Tumor With and Without Radiotherapy for Metastatic Rectal Adenocarcinoma: A National Cancer Database (NCDB) Analysis

Paul Renz et al.

CLINICAL COLORECTAL CANCER (2019)

添加到收藏夹

Review Oncology

Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition)

Jian Li et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)

添加到收藏夹

Review Oncology

Historical perspective: Two decades of progress in treating metastatic colorectal cancer

Rachel M. Lee et al.

JOURNAL OF SURGICAL ONCOLOGY (2019)

添加到收藏夹

Article Oncology

Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas

Xin-Yu Wang et al.

WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2019)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Chemotherapy, Still an Option in the Twenty-First Century in Metastatic Colorectal Cancer?

Wolfgang Eisterer et al.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY (2019)

添加到收藏夹

Article Oncology

Maintenance Therapy With Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients With RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial

Filippo Pietrantonio et al.

JAMA ONCOLOGY (2019)

添加到收藏夹

Article Medicine, General & Internal

Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer

S. Kopetz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

添加到收藏夹

Review Oncology

Parenchymal-sparing versus extended hepatectomy for colorectal liver metastases: A systematic review and meta-analysis

Gang Deng et al.

CANCER MEDICINE (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Expert Consensus Document on Pulmonary Metastasectomy

John R. Handy et al.

ANNALS OF THORACIC SURGERY (2019)

添加到收藏夹

Review Pathology

Cancer stem cells in colorectal cancer: a review

Matthew J. Munro et al.

JOURNAL OF CLINICAL PATHOLOGY (2018)

添加到收藏夹

Review Surgery

Operative Results and Oncologic Outcomes of Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Versus Two-Stage Hepatectomy (TSH) in Patients with Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-Analysis

Dimitrios Moris et al.

WORLD JOURNAL OF SURGERY (2018)

添加到收藏夹

Article Oncology

Colorectal cancer (CRC) monitoring by 6-monthly 18FDG-PET/CT: an open-label multicentre randomised trial

I. Sobhani et al.

ANNALS OF ONCOLOGY (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Pulmonary Metastasectomy for Colorectal Cancer: Predictors of Survival in Routine Surgical Practice

Sulaiman Nanji et al.

ANNALS OF THORACIC SURGERY (2018)

添加到收藏夹

Article Oncology

Colorectal cancer liver metastases - a population-based study on incidence, management and survival

Jennie Engstrand et al.

BMC CANCER (2018)

添加到收藏夹

Article Oncology

Targeting HER2 in Colorectal Cancer: The Landscape of Amplification and Short Variant Mutations in ERBB2 and ERBB3

Jeffrey S. Ross et al.

CANCER (2018)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Radiofrequency and Microwave Ablation Compared to Systemic Chemotherapy and to Partial Hepatectomy in the Treatment of Colorectal Liver Metastases: A Systematic Review and Meta-Analysis

Martijn R. Meijerink et al.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY (2018)

添加到收藏夹

Article Gastroenterology & Hepatology

Comparisons of Rigid Proctoscopy, Flexible Colonoscopy, and Digital Rectal Examination for Determining the Localization of Rectal Cancers

Akira Tanaka et al.

DISEASES OF THE COLON & RECTUM (2018)

添加到收藏夹

Article Oncology

Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study

John D. Hainsworth et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

添加到收藏夹

Article Oncology

Bevacizumab Maintenance Versus No Maintenance During Chemotherapy-Free Intervals in Metastatic Colorectal Cancer: A Randomized Phase III Trial (PRODIGE 9)

Thomas Aparicio et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

添加到收藏夹

Article Oncology

Surgical Treatment of Metastatic Colorectal Cancer

Jeffery Chakedis et al.

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (2018)

添加到收藏夹

Article Oncology

Activity and Safety of Cetuximab Plus Modified FOLFOXIRI Followed by Maintenance With Cetuximab or Bevacizumab for RAS and BRAF Wild-type Metastatic Colorectal Cancer A Randomized Phase 2 Clinical Trial

Chiara Cremolini et al.

JAMA ONCOLOGY (2018)

添加到收藏夹

Review Oncology

Metastatic Colorectal Cancer to the Peritoneum: Current Treatment Options

Nikolaos Vassos et al.

CURRENT TREATMENT OPTIONS IN ONCOLOGY (2018)

添加到收藏夹

Article Surgery

ALPPS Improves Resectability Compared With Conventional Two-stage Hepatectomy in Patients With Advanced Colorectal Liver Metastasis Results From a Scandinavian Multicenter Randomized Controlled Trial (LIGRO Trial)

Per Sandstrom et al.

ANNALS OF SURGERY (2018)

添加到收藏夹

Review Surgery

Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate, prolong survival, and potentially cure?

Camille L. Stewart et al.

CURRENT PROBLEMS IN SURGERY (2018)

添加到收藏夹

Article Oncology

Clinical and Genetic Determinants of Ovarian Metastases From Colorectal Cancer

Karuna Ganesh et al.

CANCER (2017)

添加到收藏夹

Review Gastroenterology & Hepatology

Parenchymal-Sparing Versus Anatomic Liver Resection for Colorectal Liver Metastases: a Systematic Review

Dimitrios Moris et al.

JOURNAL OF GASTROINTESTINAL SURGERY (2017)

添加到收藏夹

Article Oncology

Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial

Johan Erlandsson et al.

LANCET ONCOLOGY (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Prognostic value of pretreatment serum carbohydrate antigen 19-9 level in patients with colorectal cancer: A meta-analysis

Zhan Yu et al.

PLOS ONE (2017)

添加到收藏夹

Article Surgery

Palliative Endovascular Techniques for Management of Peripheral Vascular Blowout Syndrome in End-Stage Malignancies

Lauren A. Huntress et al.

VASCULAR AND ENDOVASCULAR SURGERY (2017)

添加到收藏夹

Article Surgery

Anatomical Resections Improve Disease-free Survival in Patients With KRAS-mutated Colorectal Liver Metastases

Georgios A. Margonis et al.

ANNALS OF SURGERY (2017)

添加到收藏夹

Article Surgery

Survival analysis of the CEAwatch multicentre clustered randomized trial

C. J. Verberne et al.

BRITISH JOURNAL OF SURGERY (2017)

添加到收藏夹

Article Oncology

A randomized study of KRAS-guided maintenance therapy with bevacizumab, erlotinib or metronomic capecitabine after first-line induction treatment of metastatic colorectal cancer: the Nordic ACT2 trial

H. Hagman et al.

ANNALS OF ONCOLOGY (2016)

添加到收藏夹

Article Oncology

Single-agent capecitabine as maintenance therapy after induction of XELOX (or FOLFOX) in first-line treatment of metastatic colorectal cancer: randomized clinical trial of efficacy and safety

H. Y. Luo et al.

ANNALS OF ONCOLOGY (2016)

添加到收藏夹

Article Oncology

Development of a Prognostic Nomogram for Patients with Peritoneally Metastasized Colorectal Cancer Treated with Cytoreductive Surgery and HIPEC

Geert A. Simkens et al.

ANNALS OF SURGICAL ONCOLOGY (2016)

添加到收藏夹

Article Oncology

XELOX vs. FOLFOX in metastatic colorectal cancer: An updated meta-analysis

Yu Guo et al.

CANCER INVESTIGATION (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

Clinicopathological Factors Associated with Recurrence and Prognosis after R0 Resection for Stage IV Colorectal Cancer with Peritoneal Metastasis

Harunobu Sato et al.

DIGESTIVE SURGERY (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

Diagnostic Accuracy of MRI for Assessment of T Category and Circumferential Resection Margin Involvement in Patients With Rectal Cancer: A Meta-Analysis

Ge Zhang et al.

DISEASES OF THE COLON & RECTUM (2016)

添加到收藏夹

Article Oncology

Cytoreductive surgery and intraperitoneal chemotherapy versus systemic chemotherapy for colorectal peritoneal metastases: A randomised trial

P. H. Cashin et al.

EUROPEAN JOURNAL OF CANCER (2016)

添加到收藏夹

Article Oncology

Meta-analysis comparing the efficacy of anti-EGFR monoclonal antibody therapy between KRAS G13D and other KRAS mutant metastatic colorectal cancer tumours

Andrew Rowland et al.

EUROPEAN JOURNAL OF CANCER (2016)

添加到收藏夹

Article Oncology

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

Andrea Sartore-Bianchi et al.

LANCET ONCOLOGY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Patterns of metastasis in colon and rectal cancer

Matias Riihimaki et al.

SCIENTIFIC REPORTS (2016)

添加到收藏夹

Meeting Abstract Oncology

Impact of primary (1°) tumor location on overall survival (OS) and progression-free survival (PFS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB/SWOG 80405 (Alliance).

Alan P. Venook et al.

JOURNAL OF CLINICAL ONCOLOGY (2016)

添加到收藏夹

Article Oncology

Bevacizumab continuation versus no continuation after first-line chemotherapy plus bevacizumab in patients with metastatic colorectal cancer: a randomized phase III non-inferiority trial (SAKK 41/06)

D. Koeberle et al.

ANNALS OF ONCOLOGY (2015)

添加到收藏夹

Article Surgery

Failure to Achieve a 2-Stage Hepatectomy for Colorectal Liver Metastases How to Prevent It?

Katsunori Imai et al.

ANNALS OF SURGERY (2015)

添加到收藏夹

Article Oncology

Recurrence After Partial Hepatectomy for Metastatic Colorectal Cancer: Potentially Curative Role of Salvage Repeat Resection

Jean M. Butte et al.

ANNALS OF SURGICAL ONCOLOGY (2015)

添加到收藏夹

Article Oncology

Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer

A. Rowland et al.

BRITISH JOURNAL OF CANCER (2015)

添加到收藏夹

Article Oncology

Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases

Lydia G. M. van der Geest et al.

CLINICAL & EXPERIMENTAL METASTASIS (2015)

添加到收藏夹

Article Oncology

Trends in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of synchronous peritoneal carcinomatosis of colorectal origin in the Netherlands

L. G. E. M. Razenberg et al.

EJSO (2015)

添加到收藏夹

Review Oncology

Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: A meta-analysis

Filippo Pietrantonio et al.

EUROPEAN JOURNAL OF CANCER (2015)

添加到收藏夹

Article Oncology

Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17

S. Y. Brule et al.

EUROPEAN JOURNAL OF CANCER (2015)

添加到收藏夹

Article Gastroenterology & Hepatology

Treatment of perforated colon carcinomas-outcomes of radical surgery

M. Daniels et al.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2015)

添加到收藏夹

Article Medicine, General & Internal

Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group

Lieke H. J. Simkens et al.

LANCET (2015)

添加到收藏夹

Article Oncology

Maintenance strategies after first-line oxaliplatin plus fluoropyrimidine plus bevacizumab for patients with metastatic colorectal cancer (AIO 0207): a randomised, non-inferiority, open-label, phase 3 trial

Susanna Hegewisch-Becker et al.

LANCET ONCOLOGY (2015)

添加到收藏夹

Article Oncology

Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study

Josep Tabernero et al.

LANCET ONCOLOGY (2015)

添加到收藏夹

Article Medicine, General & Internal

Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer

Robert J. Mayer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

添加到收藏夹

Article Oncology

Colorectal Cancer Survival Gains and Novel Treatment Regimens A Systematic Review and Analysis

Irfan Jawed et al.

JAMA ONCOLOGY (2015)

添加到收藏夹

Article Gastroenterology & Hepatology

Metachronous metastases from colorectal cancer: a population-based study in North-East Netherlands

Marloes A. G. Elferink et al.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2015)

添加到收藏夹

Review Oncology

Palliative pelvic radiotherapy of symptomatic incurable rectal cancer - a systematic review

Marte Gronlie Cameron et al.

ACTA ONCOLOGICA (2014)

添加到收藏夹

Article Oncology

Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study)

G. Folprecht et al.

ANNALS OF ONCOLOGY (2014)

添加到收藏夹

Article Oncology

Resection of Pulmonary Metastases from Colon and Rectal Cancer: Factors to Predict Survival Differ Regarding to the Origin of the Primary Tumor

G. Meimarakis et al.

ANNALS OF SURGICAL ONCOLOGY (2014)

添加到收藏夹

Article Oncology

Bevacizumab with 5-fluorouracil, leucovorin, and oxaliplatin versus bevacizumab with capecitabine and oxaliplatin for metastatic colorectal carcinoma: results of a large registry-based cohort analysis

Tomas Buchler et al.

BMC CANCER (2014)

添加到收藏夹

Article Oncology

Patterns of metachronous metastases after curative treatment of colorectal cancer

Yvette R. B. M. van Gestel et al.

CANCER EPIDEMIOLOGY (2014)

添加到收藏夹

Article Oncology

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

Sabine Venderbosch et al.

CLINICAL CANCER RESEARCH (2014)

添加到收藏夹

Article Oncology

Capecitabine Plus Irinotecan Versus 5-FU/Leucovorin Plus Irinotecan in the Treatment of Colorectal Cancer: A Meta-analysis

Yuanbiao Guo et al.

CLINICAL COLORECTAL CANCER (2014)

添加到收藏夹

Article Oncology

A multiple microwave ablation strategy in patients with initially unresectable colorectal cancer liver metastases - A safety and feasibility study of a new concept

J. Engstrand et al.

EJSO (2014)

添加到收藏夹

Article Oncology

Preoperative Magnetic Resonance Imaging Assessment of Circumferential Resection Margin Predicts Disease-Free Survival and Local Recurrence: 5-Year Follow-Up Results of the MERCURY Study

Fiona G. M. Taylor et al.

JOURNAL OF CLINICAL ONCOLOGY (2014)

添加到收藏夹

Article Gastroenterology & Hepatology

Role of surgery in colorectal cancer liver metastases

Ozgur Akgul et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

添加到收藏夹

Article Surgery

Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer

Morten Hagness et al.

ANNALS OF SURGERY (2013)

添加到收藏夹

Article Oncology

Comparison of recurrence patterns between 5 years and >5 years after curative operations in colorectal cancer patients

Seok In Seo et al.

JOURNAL OF SURGICAL ONCOLOGY (2013)

添加到收藏夹

Article Medicine, General & Internal

Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

Axel Grothey et al.

LANCET (2013)

添加到收藏夹

Article Oncology

Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial

Bernard Nordlinger et al.

LANCET ONCOLOGY (2013)

添加到收藏夹

Article Oncology

Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial

David Cunningham et al.

LANCET ONCOLOGY (2013)

添加到收藏夹

Article Medicine, General & Internal

Panitumumab-FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

Jean-Yves Douillard et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

添加到收藏夹

Article Oncology

Bevacizumab plus Capecitabine as Maintenance Therapy after Initial Bevacizumab plus XELOX Treatment in Previously Untreated Patients with Metastatic Colorectal Cancer: Phase Ill 'Stop and Go' Study Results - A Turkish Oncology Group Trial

Suayib Yalcin et al.

ONCOLOGY (2013)

添加到收藏夹

Article Surgery

Post-treatment surveillance of patients with colorectal cancer with surgically treated liver metastases

Omar Hyder et al.

SURGERY (2013)

添加到收藏夹

Article Surgery

A prospective evaluation of short-term and long-term results from colonic stenting for palliation or as a bridge to elective operation versus immediate surgery for large-bowel obstruction

Luca Gianotti et al.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2013)

添加到收藏夹

Article Surgery

Palliative management for patients with subacute obstruction and stage IV unresectable rectosigmoid cancer: colostomy versus endoscopic stenting: final results of a prospective randomized trial

Enrico Fiori et al.

AMERICAN JOURNAL OF SURGERY (2012)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Is Lymph Node Dissection Required in Pulmonary Metastasectomy for Colorectal Adenocarcinoma?

Masatsugu Hamaji et al.

ANNALS OF THORACIC SURGERY (2012)

添加到收藏夹

Article Gastroenterology & Hepatology

A critical appraisal of endorectal ultrasound and transanal endoscopic microsurgery and decision-making in early rectal cancer

S. Ashraf et al.

COLORECTAL DISEASE (2012)

添加到收藏夹

Article Oncology

Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

Eric Van Cutsem et al.

JOURNAL OF CLINICAL ONCOLOGY (2012)

添加到收藏夹

Article Oncology

High Survival Rate After Two-Stage Resection of Advanced Colorectal Liver Metastases: Response-Based Selection and Complete Resection Define Outcome

Antoine Brouquet et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

添加到收藏夹

Article Oncology

Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status

Eric Van Cutsem et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

添加到收藏夹

Article Gastroenterology & Hepatology

Metastasectomy for Stage IV Colorectal Cancer

Najjia Mahmoud et al.

DISEASES OF THE COLON & RECTUM (2010)

添加到收藏夹

Article Gastroenterology & Hepatology

Epidemiology, management and prognosis of colorectal cancer with lung metastases: a 30-year population-based study

Emmanuel Mitry et al.

GUT (2010)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Diagnostic Imaging of Colorectal Liver Metastases with CT, MR Imaging, FDG PET, and/or FDG PET/CT: A Meta-Analysis of Prospective Studies Including Patients Who Have Not Previously Undergone Treatment

Maarten Christian Niekel et al.

RADIOLOGY (2010)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Non-imaged pulmonary nodules discovered during thoracotomy for metastasectomy by lung palpation

Robert James Cerfolio et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2009)

添加到收藏夹

Article Oncology

Can Chemotherapy Be Discontinued in Unresectable Metastatic Colorectal Cancer? The GERCOR OPTIMOX2 Study

Benoist Chibaudel et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

添加到收藏夹

Article Oncology

Evidence for Cure by Adjuvant Therapy in Colon Cancer: Observations Based on Individual Patient Data From 20,898 Patients on 18 Randomized Trials

Daniel Sargent et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

添加到收藏夹

Article Medicine, General & Internal

Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial

David Sebag-Montefiore et al.

LANCET (2009)

添加到收藏夹

Article Surgery

Rates and Patterns of Recurrence Following Curative Intent Surgery for Colorectal Liver Metastasis An International Multi-Institutional Analysis of 1669 Patients

Mechteld C. de Jong et al.

ANNALS OF SURGERY (2009)

添加到收藏夹

Article Surgery

Systematic extended right posterior sectionectomy - A safe and effective alternative to right hepatectomy

Guido Torzilli et al.

ANNALS OF SURGERY (2008)

添加到收藏夹

Article Oncology

Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer:: A randomized phase III study

Leonard B. Saltz et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

添加到收藏夹

Article Oncology

Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: Results of the TREE study

Howard S. Hochster et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

添加到收藏夹

Article Surgery

Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases

Srinevas K. Reddy et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2008)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Microwave ablation of lung malignancies: Effectiveness, CT findings, and safety in 50 patients

Farrah J. Wolf et al.

RADIOLOGY (2008)

添加到收藏夹

Article Oncology

Two-stage hepatectomy approach for initially unresectable colorectal hepatic metastases

Rene Adam et al.

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (2007)

添加到收藏夹

Article Oncology

Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200

Bruce J. Giantonio et al.

JOURNAL OF CLINICAL ONCOLOGY (2007)

添加到收藏夹

Review Oncology

Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group

Bernard Nordlinger et al.

EUROPEAN JOURNAL OF CANCER (2007)

添加到收藏夹

Article Surgery

Neoadjuvant chemotherapy and resection of advanced synchronous liver metastases before treatment of the colorectal primary

G. Mentha et al.

BRITISH JOURNAL OF SURGERY (2006)

添加到收藏夹

Article Oncology

Colorectal cancer surveillance: 2005 update of an American Society of Clinical Oncology practice guideline

CE Desch et al.

JOURNAL OF CLINICAL ONCOLOGY (2005)

添加到收藏夹

Article Oncology

Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab

FA Scappaticci et al.

JOURNAL OF SURGICAL ONCOLOGY (2005)

添加到收藏夹

Article Oncology

Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A Multicenter study of the Gruppo Oncologico Dell'Italia Meridionale

G Colucci et al.

JOURNAL OF CLINICAL ONCOLOGY (2005)

添加到收藏夹

Article Oncology

Addition of bevacizurnab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial

FF Kabbinavar et al.

JOURNAL OF CLINICAL ONCOLOGY (2005)

添加到收藏夹

Article Oncology

FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer:: A randomized GERCOR study

C Tournigand et al.

JOURNAL OF CLINICAL ONCOLOGY (2004)

添加到收藏夹

Review Radiology, Nuclear Medicine & Medical Imaging

Rectal cancer: Local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging - A meta-analysis

S Bipat et al.

RADIOLOGY (2004)

添加到收藏夹

Article Surgery

A two-stage hepatectomy procedure combined with portal vein embolization to achieve curative resection for initially unresectable multiple and bilobar colorectal liver metastases

D Jaeck et al.

ANNALS OF SURGERY (2004)

添加到收藏夹

Article Medicine, General & Internal

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

H Hurwitz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

添加到收藏夹

Article Oncology

Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer

VJ Verwaal et al.

JOURNAL OF CLINICAL ONCOLOGY (2003)

添加到收藏夹

Article Surgery

Anatomical bi- and trisegmentectomies as alternatives to extensive liver resections

E Chouillard et al.

ANNALS OF SURGERY (2003)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.