期刊
JOURNAL OF CLINICAL MEDICINE
卷 12, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/jcm12062321
关键词
multimorbidity; elderly; aortic; stiffness
Multimorbidity, driven by an aging population, is the coexistence of multiple health conditions, including hypertension, heart disease, chronic kidney disease, anemia, etc., in elderly individuals. Regular exercise, salt restriction, statins, and blood pressure control are interventions that can delay arterial stiffness progression and decrease multimorbidity in the elderly.
Multimorbidity, the coexistence of multiple health conditions in an individual, has emerged as one of the greatest challenges facing health services, and this crisis is partly driven by the aging population. Aging is associated with increased aortic stiffness (AoStiff), which in turn is linked with several morbidities frequently affecting and having disastrous consequences for the elderly. These include hypertension, ischemic heart disease, heart failure, atrial fibrillation, chronic kidney disease, anemia, ischemic stroke, and dementia. Two or more of these disorders (multimorbidity) often coexist in the same elderly patient and the specific multimorbidity pattern depends on several factors including sex, ethnicity, common morbidity routes, morbidity interactions, and genomics. Regular exercise, salt restriction, statins in patients at high atherosclerotic risk, and stringent blood pressure control are interventions that delay progression of AoStiff and most likely decrease multimorbidity in the elderly.
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