Tuning the Effect of Chitosan on the Electrochemical Responsiveness of Lignin Nanoparticles

Chitosan and ligninmixed nanoparticles were preparedby layer-by-layerand nanoprecipitation methodologies as responsive platforms for sustainablebiosensors. The novel nanoparticles showed effective chemophysicaland electrochemical properties dependent on the preparation methodology,molecular weight of chitosan, and type of lignin. HOMO-LUMOenergy gap calculations suggested the presence of structure-activityrelationships between the electrochemical responsiveness and the orderand orientation of lignin aromatic subunits and chitosan chains inthe nanodevices.

Automated summary

Chitosan and lignin mixed nanoparticles were prepared using layer-by-layer and nanoprecipitation methodologies as sustainable biosensor platforms. The nanoparticles exhibited effective chemophysical and electrochemical properties, depending on the preparation methodology, chitosan molecular weight, and lignin type. HOMO-LUMO energy gap calculations indicated the existence of structure-activity relationships between electrochemical responsiveness and the order and orientation of lignin aromatic subunits and chitosan chains in the nanodevices.