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Article
Anthropology
Victoria N. Mutiso et al.
Summary: This study aimed to assess the validity and reliability of a culturally adapted version of the Edinburgh Postnatal Depression Scale (EPDS) in a local dialect (Kamba) in Kenya. The results showed that EPDS had good utility in detecting depressive disorder in Kamba-speaking postnatal women and can be administered by trained lay interviewers.
TRANSCULTURAL PSYCHIATRY
(2023)
Article
Cell Biology
Yumeng Miao et al.
Summary: Morin inhibits Th17 differentiation and alleviates rheumatoid arthritis by limiting fatty acid synthesis via activating PPAR gamma.
CELL BIOLOGY AND TOXICOLOGY
(2023)
Article
Psychiatry
Berta Moreno-Kustner et al.
Summary: The PRISS is a reliable and valid scale for measuring subjective experiences in patients with schizophrenia. It provides valuable information complementary to clinical evaluation.
ACTA PSYCHIATRICA SCANDINAVICA
(2022)
Article
Nursing
Michelle van Dam et al.
Summary: This study explores the challenges of implementing Cognitive Adaptation Training (CAT) in psychiatric care and identifies the factors influencing implementation. The results show that in addition to facilitators at the intervention and nursing levels, barriers at the organizational level need to be overcome. Future implementation initiatives should focus on providing ongoing training and supervision for CAT specialists, appointing local champions to enhance commitment among nursing staff, and involving management to address organizational barriers.
JOURNAL OF PSYCHIATRIC AND MENTAL HEALTH NURSING
(2022)
Article
Neurosciences
Alba Toll et al.
Summary: This study suggests that low baseline BDNF levels, smaller left amygdala relative volume, and score on the PANSS negative subscale are significant predictors of outcomes in first-episode psychosis. These findings could help tailor treatments for individuals with first-episode psychosis.
JOURNAL OF PSYCHIATRY & NEUROSCIENCE
(2022)
Article
Psychiatry
Pierre Lavaud et al.
Summary: The utilization of long-term care facilities is high among older patients with schizophrenia, and is significantly associated with factors such as higher levels of depression, lower cognitive functioning, more frequent hospitalizations in psychiatric departments, lack of consultations with general practitioners, urban living, and older age.
PSYCHIATRY RESEARCH
(2022)
Article
Psychiatry
Anthony O. Ahmed et al.
Summary: Negative symptom studies should use multidimensional models instead of single composite scores. This study compared different models using structural equation modeling and found that a five-dimensional model best captures the relationship between negative symptoms and other variables.
SCHIZOPHRENIA BULLETIN
(2022)
Article
Multidisciplinary Sciences
Sam Burgin et al.
Summary: Recent studies have explored self-disorders as the clinical core of the schizophrenia spectrum, but there have been few discussions on the quality and utility of the assessment tools. This study conducted a literature search and meta-analysis, finding that self-disorders are more aggregated within schizophrenia spectrum groups compared to non-schizophrenia spectrum groups, and have a greater likelihood of occurring within SSDs.
SCIENTIFIC REPORTS
(2022)
Review
Medicine, General & Internal
Claudia Bull et al.
Summary: This study aims to assess the psychometric properties of maternity patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) and evaluate their woman-centricity. The study will use a systematic review approach guided by the COSMIN guideline. The findings will be used to develop a maternity PROMs and PREMs database to support service and system performance measurement, and value-based maternity care initiatives.
Article
Psychiatry
Elmars Rancans et al.
Summary: This perspective paper aims to shed light on the appropriate dosing strategies of cariprazine, a novel antipsychotic medication, through summarizing clinical data and real-world evidence.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Biochemistry & Molecular Biology
Joao E. Rodrigues et al.
Summary: Mass spectrometry (MS)-based proteomics can effectively identify biomarkers and relevant biological pathways in schizophrenia (SCZ) patients, providing potential targets for prediction and diagnosis improvement. This study identified 217 differentially expressed proteins in SCZ patients through meta-analysis of 19 articles using MS proteomics approaches. Enriched biological pathways included lipid metabolism, complement and coagulation cascades, and immune response. The upregulation of FCN3 and downregulation of APO1, APOA2, APOC1, and APOC3 were suggested as potential biomarkers for SCZ. However, heterogeneity in the findings and confounding factors should be taken into account for future studies to enhance the understanding of differentially expressed proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Psychiatry
Benjamin Buck et al.
Summary: This review provides an initial guide to the use of measurement-based care (MBC) in the treatment of schizophrenia by reporting on psychometric studies of PROMs. The findings suggest that there are robust options for assessing symptom outcomes in schizophrenia, with measures showing strengths in internal consistency, reliability, and validity. Multiple measures demonstrated promising psychometric strengths, indicating their potential value in the context of MBC for schizophrenia.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Review
Psychiatry
Guru S. Gowda et al.
Summary: The review highlights the cost-effectiveness and efficacy of Assertive Community Treatment (ACT), Intensive Case Management (ICM), and Crisis Intervention as interventions for schizophrenia, especially in high-income countries. Tailor-made models based on these interventions have shown success in reducing substance use, homelessness, and criminal activity in community-dwelling individuals with schizophrenia.
CURRENT PSYCHIATRY REPORTS
(2022)
Review
Psychiatry
Daisy L. Spark et al.
Summary: Despite decades of drug discovery, current antipsychotics have limited efficacy in treating negative and cognitive symptoms of schizophrenia. The lack of translation between preclinical and clinical efficacy suggests a systematic failure in determining efficacy in preclinical rodent models. This review critically evaluates the current rodent models and behavioral tests used in preclinical efficacy research and proposes the use of objective, clinically informed measures to improve translational validity.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Psychiatry
C. Carswell et al.
Summary: This study explores the lived experience of individuals with severe mental illness and long-term physical conditions. It finds that people with co-existing mental illness and physical conditions often face significant barriers to self-management of their health due to competing demands and limited support. Providing social support and person-centred care is crucial for managing health in this population.
Review
Pharmacology & Pharmacy
Javier-David Lopez-Morinigo et al.
Summary: Treatment of early-onset schizophrenia needs to consider the unmet needs in cognition, functioning, quality of life, suicidal behavior, mortality, services utilization, and cost-effectiveness. Some drugs have been proven effective but also have side effects, more research is needed to meet the unmet needs.
PHARMACOPSYCHIATRY
(2022)
Article
Psychiatry
Samuel J. Abplanalp et al.
Summary: This study utilized network psychometrics to explore the associations and structure between positive symptoms, negative symptoms, and functional domains in individuals with schizophrenia. The findings indicate that anhedonia plays a central role and is connected to multiple functional domains.
Article
Environmental Sciences
Renata Piotrkowska et al.
Summary: Most patients undergoing vascular surgeries showed high or moderate levels of nicotine dependence and low motivation to quit smoking. The higher the nicotine addiction, the lower the motivation to quit. Social and demographic factors do not affect the degree of nicotine addiction and motivation to quit smoking.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Psychiatry
Gabriele Nibbio et al.
Summary: Schizophrenia Spectrum Disorders (SSD) and Autism Spectrum Disorders (ASD) are considered separate entities, but there are important similarities between the two spectra. This systematic review examines the use of the PANSS Autism Score (PAUSS) in assessing autistic symptoms in people with SSD and analyzes the cognitive, functional, and neurobiological correlates of these symptoms. The results show that autistic symptoms in individuals with SSD are associated with poorer cognitive performance, particularly in the social cognition domain, and worse psychosocial functioning. However, the presence of autistic symptoms may also have a protective role on functioning in individuals with more severe psychotic symptoms. Further research on the impact of autistic symptoms could be of great scientific and clinical interest.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Medicine, General & Internal
Ezgi Ince Guliyev et al.
Summary: This study compared effort allocation capacity between patients with recent-onset schizophrenia and healthy controls, and investigated the association of effort allocation capacity with negative symptoms within the schizophrenia group. The results showed that patients with schizophrenia exhibited a general reduction in effort allocation capacity and made inefficient choices. The effects of negative symptoms on effort expenditure were more pronounced when the rewarding stimulus was vague.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychology, Clinical
Sara Jalali-Farahani et al.
Summary: This study developed and assessed the psychometric properties of an indigenous scale for body image evaluation among Iranian adolescents, and found that gender and body weight status have significant effects on body dissatisfaction. These findings are important for the development of future health promotion programs targeting overweight and obesity in adolescents.
JOURNAL OF EATING DISORDERS
(2022)
Article
Psychiatry
Kiyoka Enomoto et al.
Summary: This study aimed to develop and validate the psychometric properties of the Japanese version of the POAM-P (POAM-P-J) in Japanese individuals with chronic pain. The results confirmed the internal consistency, test-retest reliability, and concurrent validity of the POAM-P-J, although its structural validity remains questionable. The POAM-P-J is useful in both research and clinical practice for evaluating the activity patterns of Japanese patients with chronic pain.
BIOPSYCHOSOCIAL MEDICINE
(2022)
Article
Surgery
Sattar Mahmoudi et al.
Summary: The study confirmed that the Iranian version of ROE is a valid instrument for assessing outcomes in rhinoplasty patients. The research demonstrated internal consistency and validity of the questionnaire.
WORLD JOURNAL OF PLASTIC SURGERY
(2022)
Article
Psychology, Multidisciplinary
Man-Man Peng et al.
Summary: The study examined the long-term caregiving experiences of family caregivers of people with schizophrenia, highlighting the caregivers' burden, psychological status, coping strategies, and potential patient-related consequences. Recommendations include developing stress management skills, empowering care recipients to take care of themselves, and providing more effective family-based interventions tailored to diverse needs.
Article
Clinical Neurology
Leslie Citrome et al.
Summary: This study suggests that clinicians may be reluctant to discuss or recommend switching patients to an LAI antipsychotic medication if they are perceived as doing well on current therapy. A clinician's perception of relapse was a strong driver of whether or not the clinician would discuss/recommend an LAI antipsychotic medication.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Review
Medicine, General & Internal
Angela C. Wolff et al.
Summary: This systematic review aims to synthesize evidence on how healthcare providers implement individual-level PROMs and PREMs data into daily practice. The methods include peer-reviewed research evidence in qualitative, quantitative, and mixed methods, as well as systematic reviews and organizational implementation projects. Data management will be conducted using NVivo 12(TM) for data extraction and synthesis.
SYSTEMATIC REVIEWS
(2021)
Review
Psychiatry
Ling-Ling Wang et al.
Summary: The study explored the relationship between amotivation and value representation, and how the brain utilizes external information to represent value. The results indicated that patients at different stages of schizophrenia spectrum exhibit distinct patterns in their range adaptation abilities.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Psychiatry
Sophie E. Legge et al.
Summary: The study found that in patients with schizophrenia, disorganized symptoms and cognitive ability are associated with genetic liability to schizophrenia, while cognitive ability is also related to genetic risk for intelligence.
Article
Psychiatry
Mariia Kaliuzhna et al.
SCHIZOPHRENIA RESEARCH
(2020)
Article
Psychology, Clinical
Chris Keyworth et al.
BRITISH JOURNAL OF HEALTH PSYCHOLOGY
(2020)
Article
Psychiatry
L. Aimola et al.
Article
Public, Environmental & Occupational Health
W. Scott Comulada et al.
PUBLIC HEALTH NUTRITION
(2018)
