相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Natural product-based nanoformulations for cancer therapy: Opportunities and challenges
Dharambir Kashyap et al.
SEMINARS IN CANCER BIOLOGY (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
The ever-increasing importance of cancer as a leading cause of premature death worldwide
Freddie Bray et al.
CANCER (2021)
Recent progress of oridonin and its derivatives for cancer therapy and drug resistance
Yong-Feng Guan et al.
MEDICINAL CHEMISTRY RESEARCH (2021)
Oridonin: A Review of Its Pharmacology, Pharmacokinetics and Toxicity
Xiang Li et al.
FRONTIERS IN PHARMACOLOGY (2021)
Oridonin and its derivatives for cancer treatment and overcoming therapeutic resistance
Xi Liu et al.
GENES & DISEASES (2021)
Oridonin inhibits epithelial-mesenchymal transition of human nasopharyngeal carcinoma cells by negatively regulating AKT/STAT3 signaling pathway
Wei Liu et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)
Hydrogen sulfide releasing oridonin derivatives induce apoptosis through extrinsic and intrinsic pathways
Haonan Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Solubility and Bioavailability Enhancement of Oridonin: A Review
Yuanyuan Zhang et al.
MOLECULES (2020)
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2020)
Oridonin enhances the anti-tumor activity of gemcitabine towards pancreatic cancer by stimulating Bax- and Smac-dependent apoptosis
Dian-Lei Liu et al.
TRANSLATIONAL CANCER RESEARCH (2020)
Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer
Hong Yao et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Natural Products as Modulators of Sirtuins
Berin Karaman Mayack et al.
MOLECULES (2020)
Oridonin Improves the Sensitivity of Multiple Myeloma Cells to Bortezomib through the PTEN/PI3K/Akt Pathway
Hong Wu et al.
CURRENT TOPICS IN NUTRACEUTICAL RESEARCH (2020)
Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways
Jin-Huan Jiang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
ROS/JNK/c-Jun axis is involved in oridonin-induced caspase-dependent apoptosis in human colorectal cancer cells
Di Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Synthesis, and evaluation of in vitro and in vivo anticancer activity of 14-substituted oridonin analogs: A novel and potent cell cycle arrest and apoptosis inducer through the p53-MDM2 pathway
Qing-Kun Shen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Oridonin inhibits hypoxia-induced epithelial-mesenchymal transition and cell migration by the hypoxia-inducible factor-1α/matrix metallopeptidase-9 signal pathway in gallbladder cancer
Kunlun Chen et al.
ANTI-CANCER DRUGS (2019)
Oridonin, A natural diterpenoid, protected NGF-differentiated PC12 cells against MPP+ - and kainic acid-induced injury
Kuan-Ho Lin et al.
FOOD AND CHEMICAL TOXICOLOGY (2019)
Homoharringtonine synergy with oridonin in treatment of t(8;21) acute myeloid leukemia
Weina Zhang et al.
FRONTIERS OF MEDICINE (2019)
Protective Effects of Oridonin on Intestinal Epithelial Cells by Suppressing TNFα-Induced Inflammation and Epithelial-Mesenchymal Transition
Claire Cummins et al.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2019)
Synthesis of Oridonin Derivatives via Mizoroki-Heck Reaction and Click Chemistry for Cytotoxic Activity
Wei Hou et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2019)
Synergistic antitumor activity of oridonin and valproic acid on HL-60 leukemia cells
Wei Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Design and synthesis of novel oridonin analogues as potent anticancer agents
Qing-Kun Shen et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2018)
Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection
Jimin Xu et al.
MOLECULES (2018)
Oridonin inhibits VEGF-A-associated angiogenesis and epithelial-mesenchymal transition of breast cancer in vitro and in vivo
Chunyu Li et al.
ONCOLOGY LETTERS (2018)
Oridonin Targets Multiple Drug-Resistant Tumor Cells as Determined by in Silico and in Vitro Analyses
Onat Kadioglu et al.
FRONTIERS IN PHARMACOLOGY (2018)
Oridonin enhances the radiosensitivity of lung cancer cells by upregulating Bax and downregulating Bcl-2
Sirui Li et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)
Oridonin induces growth inhibition and apoptosis in human gastric carcinoma cells by enhancement of p53 expression and function
Enxu Bi et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2018)
Oridonin promotes G2/M arrest in A549 cells by facilitating ATM activation
Mingxing Zheng et al.
MOLECULAR MEDICINE REPORTS (2017)
Oridonin induces apoptosis in human oral cancer cells via phosphorylation of histone H2AX
In-Hyoung Yang et al.
EUROPEAN JOURNAL OF ORAL SCIENCES (2017)
A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway
Shengtao Xu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells
Zhuo Yao et al.
CELL DEATH & DISEASE (2017)
Oridonin induces apoptosis and reverses drug resistance in cisplatin resistant human gastric cancer cells
Zhongwei He et al.
ONCOLOGY LETTERS (2017)
Oridonin induces G2/M cell cycle arrest and apoptosis via the PI3K/Akt signaling pathway in hormone-independent prostate cancer cells
Jianlei Lu et al.
ONCOLOGY LETTERS (2017)
Oridonin synergistically enhances JQ1-triggered apoptosis in hepatocellular cancer cells through mitochondrial pathway
Hua-Peng Zhang et al.
ONCOTARGET (2017)
The value of pyrans as anticancer scaffolds in medicinal chemistry
Dinesh Kumar et al.
RSC ADVANCES (2017)
Reactive oxygen species mediate oridonin-induced apoptosis through DNA damage response and activation of JNK pathway in diffuse large B cell lymphoma
Zi-Zhen Xu et al.
LEUKEMIA & LYMPHOMA (2016)
Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies
Shengtao Xu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Discovery and development of natural product oridonin-inspired anticancer agents
Ye Ding et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound
Dahong Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Combined oridonin with cetuximab treatment shows synergistic anticancer effects on laryngeal squamous cell carcinoma: Involvement of inhibition of EGFR and activation of reactive oxygen species-mediated JNK pathway
Shijie Cao et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Oridonin Alleviates Visceral Hyperalgesia in a Rat Model of Postinflammatory Irritable Bowel Syndrome: Role of Colonic Enterochromaffin Cell and Serotonin Availability
Kai-hong Zang et al.
JOURNAL OF MEDICINAL FOOD (2016)
Protective effects of oridonin on the sepsis in mice
Yan-Jun Zhao et al.
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES (2016)
Antitumor and Antibacterial Derivatives of Oridonin: A Main Composition of Dong-Ling-Cao
Dahong Li et al.
MOLECULES (2016)
Oridonin suppress cell migration via regulation of nonmuscle myosin IIA
Yin-Chao Li et al.
CYTOTECHNOLOGY (2016)
Oridonin induces apoptosis in uveal melanoma cells by upregulation of Bim and downregulation of Fatty Acid Synthase
Zhimin Gu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis
Fredrick J. Bohanon et al.
JOURNAL OF SURGICAL RESEARCH (2014)
Enhancement of the effects of gemcitabine against pancreatic cancer by oridonin via the mitochondrial caspase-dependent signaling pathway
Dian-Lei Liu et al.
MOLECULAR MEDICINE REPORTS (2014)
ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids
Chunyong Ding et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Novel Hybrids of Natural Oridonin-Bearing Nitrogen Mustards as Potential Anticancer Drug Candidates
Shengtao Xu et al.
ACS MEDICINAL CHEMISTRY LETTERS (2014)
Amino acids as promoieties in prodrug design and development
Balvinder S. Vig et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Enmein-type diterpenoid analogs from natural kaurene-type oridonin: Synthesis and their antitumor biological evaluation
Dahong Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Synthesis of spirolactone-type diterpenoid derivatives from kaurene-type oridonin with improved antiproliferative effects and their apoptosis-inducing activity in human hepatoma Bel-7402 cells
Dahong Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Oridonin suppresses transplant rejection by depleting T cells from the periphery
Wenzhi Guo et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2013)
The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells
Hiu-Yee Kwan et al.
JOURNAL OF GASTROENTEROLOGY (2013)
Novel Nitrogen-Enriched Oridonin Analogues with Thiazole-Fused A-Ring: Protecting Group-Free Synthesis, Enhanced Anticancer Profile, and Improved Aqueous Solubility
Chunyong Ding et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Oridonin Ring A-Based Diverse Constructions of Enone Functionality: Identification of Novel Dienone Analogues Effective for Highly Aggressive Breast Cancer by Inducing Apoptosis
Chunyong Ding et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: Synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents
Lei Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells
Hui Wang et al.
ONCOLOGY REPORTS (2010)
Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates
Jinyi Xu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Pharmacokinetic behaviors and oral bioavailability of oridonin in rat plasma
Wen Xu et al.
ACTA PHARMACOLOGICA SINICA (2006)
Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL-7402 cells
Jun-Feng Zhang et al.
HEPATOLOGY RESEARCH (2006)
分享论文
