Between noise and function: Toward a taxonomy of the non-canonical translatome

Eukaryotic genomes are pervasively translated, but the properties of translated sequences outside of canon-ical genes are poorly understood. A new study in Cell Systems reveals a large translatome that is not under significant evolutionary constraint but is still an active part of diverse cellular systems.

Automated summary

A recent study in Cell Systems uncovers a substantial translatome that lacks significant evolutionary constraint but plays an active role in various cellular systems.