4.7 Article

Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Meeting Abstract Biochemistry & Molecular Biology

Xanthine Oxidase has a Protective Role During Heme Crisis by Binding Heme and Facilitating Degradation

Heidi Schmidt et al.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

Article Hematology

Xanthine Oxidase Drives Hemolysis and Vascular Malfunction in Sickle Cell Disease

Heidi M. Schmidt et al.

Summary: In a mouse model of sickle cell disease, treatment with XO inhibitor febuxostat for 10 weeks significantly decreased hemolysis and improved pulmonary vasoreactivity. Although hepatic XO accounts for >50% of circulating XO, it is not the driver of hemolysis in SCD.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)

Article Public, Environmental & Occupational Health

COVID-19 pandemic and worldwide organ transplantation: a population-based study

Olivier Aubert et al.

Summary: The study evaluated the impact of the COVID-19 pandemic on worldwide organ transplantation activities and found an overall decrease in transplant activity in all countries studied. Kidney transplantation was most affected, followed by lung, liver, and heart transplants. There was a marked reduction in transplant activity during the first 3 months of the pandemic, with losses stabilizing after June 2020 but decreasing again from October to December 2020.

LANCET PUBLIC HEALTH (2021)

Article Clinical Neurology

Sleep phenotype in the Townes mouse model of sickle cell disease

Brett J. O'Donnell et al.

SLEEP AND BREATHING (2019)

Review Medicine, General & Internal

Sickle cell disease: a review for the internist

Valeria Maria Pinto et al.

INTERNAL AND EMERGENCY MEDICINE (2019)

Article Public, Environmental & Occupational Health

Challenges of achieving sustainable community health services for community case management of malaria

Michelle D. S. Boakye et al.

BMC PUBLIC HEALTH (2018)

Article Cardiac & Cardiovascular Systems

Current Practice of State-of-the-Art Surgical Coronary Revascularization

Stuart J. Head et al.

CIRCULATION (2017)

Article Critical Care Medicine

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis

Carolin Fleischmann et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)

Review Biochemistry & Molecular Biology

Hemoglobin-mediated nitric oxide signaling

Christine Helms et al.

FREE RADICAL BIOLOGY AND MEDICINE (2013)

Article Medicine, Research & Experimental

Extracellular hemin crisis triggers acute chest syndrome in sickle mice

Samit Ghosh et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Hematology

Mechanisms of hemolysis-associated platelet activation

C. C. Helms et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)

Article Multidisciplinary Sciences

Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

Adam C. Straub et al.

NATURE (2012)

Review Hematology

Measurement of Red Cell Lifespan and Aging

Robert S. Franco

TRANSFUSION MEDICINE AND HEMOTHERAPY (2012)

Article Medicine, General & Internal

Sickle-cell disease

David C. Rees et al.

LANCET (2010)

Review Medicine, General & Internal

Pulmonary Complications of Sickle Cell Disease.

Mark T. Gladwin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Physiology

Hypoxia-induced acute lung injury in murine models of sickle cell disease

KA Pritchard et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)

Article Biochemistry & Molecular Biology

Hemoglobin redox reactions and oxidative stress

JM Rifkind et al.

REDOX REPORT (2003)

Article Multidisciplinary Sciences

Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease

M Aslan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Medical Laboratory Technology

Hemopexin: a review of biological aspects and the role in laboratory medicine

JR Delanghe et al.

CLINICA CHIMICA ACTA (2001)

Article Biochemistry & Molecular Biology

Reaction of hydrogen peroxide with ferrylhemoglobin: Superoxide production and heme degradation

E Nagababu et al.

BIOCHEMISTRY (2000)