☆ 4.6 Review

Iranian clinical practice guideline for amyotrophic lateral sclerosis

FRONTIERS IN NEUROLOGY (2023)

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Article Rehabilitation

Healthcare professionals' involvement in breaking bad news to newly diagnosed patients with motor neurodegenerative conditions: a qualitative study

Eleftherios Anestis et al.

Summary: The study found that non-medical healthcare professionals play an important role in delivering bad news to newly diagnosed patients with motor neurodegenerative conditions in the UK. They are involved in supporting patients, reiterating diagnostic information, and helping patients understand the impact of their condition, ultimately empowering patients to regain control over their health and lives.

DISABILITY AND REHABILITATION (2022)

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Article Clinical Neurology

Embedded Psychiatric Services in a Multidisciplinary Amyotrophic Lateral Sclerosis Clinic: An Assessment of Patient Needs and Perceptions

Morgan Hardy et al.

Summary: The study involved embedding psychiatric services within a multidisciplinary clinic to evaluate and treat neuropsychiatric symptoms in ALS patients. Both patients and family members found meeting with a psychiatrist helpful and expressed a desire for continued access to psychiatric care in the future. This highlights the potential benefits of including psychiatrists in the care team for ALS patients.

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES (2022)

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Review Health Care Sciences & Services

Prevalence of Sialorrhea Among Amyotrophic Lateral Sclerosis Patients: A Systematic Review and Meta-Analysis

Yao Wang et al.

Summary: This study conducted a systematic review and meta-analysis of the prevalence of sialorrhea in ALS patients worldwide and found that sialorrhea is a relatively common symptom in ALS patients with a high prevalence. The study suggests that sialorrhea should be evaluated using more complex professional assessment scales to improve quality of life and early prognosis of the disease.

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2022)

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Article Otorhinolaryngology

A Novel Method for Triggering the Swallowing Reflex in Patients with Amyotrophic Lateral Sclerosis: the Ishizaki Press Method

Naohiko Ishizaki et al.

Summary: This study identified seven specific maxillofacial points triggering the swallowing reflex by finger pressure, with an efficacy of >= 70%. Stimulation at these points induced rapid swallowing reflex in less than 10 seconds, improving the management of dysphagia in patients with amyotrophic lateral sclerosis.

DYSPHAGIA (2022)

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Article Clinical Neurology

A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis

Merit E. Cudkowicz et al.

Summary: This study evaluated the efficacy of mesenchymal stem cells induced to secrete neurotrophic factors in slowing the progression of ALS. The results suggest that this therapy may have a positive effect on patients with less severe disease, but did not reach statistical significance on the primary endpoint.

MUSCLE & NERVE (2022)

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Article Clinical Neurology

Overcoming therapeutic nihilism. Breaking bad news of amyotrophic lateral sclerosis-a patient-centred perspective in rare diseases

Stanislaw Maksymowicz et al.

Summary: This article discusses the issue of delivering bad news to ALS patients in Poland and finds shortcomings in existing guidelines. Patients also have to deal with therapeutic nihilism and their end-of-life needs not being met. The study suggests using extended breaking bad news protocols and addressing the patients' treatment plan, hope, and psychological support.

NEUROLOGICAL SCIENCES (2022)

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Article Clinical Neurology

Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis

Simon Witzel et al.

Summary: This study found that long-term intravenous edaravone therapy for patients with ALS was feasible and well tolerated, but did not provide any disease-modifying benefit compared to standard therapy.

JAMA NEUROLOGY (2022)

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Review Clinical Neurology

A systematic review of non-motor symptom evaluation in clinical trials for amyotrophic lateral sclerosis

Emily Beswick et al.

Summary: Non-motor symptoms like neuropsychiatric, cognitive and behavioral changes, pain, fatigue, and disordered sleep have not been consistently evaluated in ALS clinical trials. When evaluated, these symptoms were mainly assessed using instruments not adapted for individuals with ALS. Future trials should include assessments of non-motor symptoms to explore potential therapeutic benefits.

JOURNAL OF NEUROLOGY (2022)

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Article Clinical Neurology

Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial

Sabrina Paganoni et al.

Summary: Early use of PB/TURSO can prolong tracheostomy/ventilation-free survival in ALS patients and delay the first hospitalization.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)

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Article Clinical Neurology

Higher incidence of cervical spinal cord compression in amyotrophic lateral sclerosis: a single-institute cohort study

Kosuke Matsuzono et al.

Summary: Among ALS, PD, and CIDP patients, the proportion of cervical spondylotic myelopathy (CSM) was highest in ALS patients, with cervical cord conditions significantly more crowded in ALS patients compared to others.

NEUROLOGICAL SCIENCES (2022)

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Article Clinical Neurology

Awaji criteria for the diagnosis of amyotrophic lateral sclerosis in Hanoi, Vietnam

Tuan Van Nguyen et al.

Summary: The study evaluated the role of electromyography and Awaji criteria for the early diagnosis of ALS, finding that Awaji criteria have higher sensitivity for early diagnosis of ALS.

NEUROLOGICAL SCIENCES (2022)

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Article Clinical Neurology

Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis

Stephen A. Goutman et al.

Summary: The diagnosis of amyotrophic lateral sclerosis can be challenging due to its diverse clinical presentation and overlap with other neurological disorders. However, an evolving understanding of the disease and the use of new diagnostic criteria can expedite diagnosis. Additionally, advancements in prognosis and monitoring tools are also being developed.

LANCET NEUROLOGY (2022)

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Article Medicine, General & Internal

Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

Timothy M. Miller et al.

Summary: This study examined the use of tofersen in patients with SOD1 ALS and found that it can reduce protein concentrations in the cerebrospinal fluid and plasma, but does not improve clinical outcomes and is associated with adverse events. Further investigation is needed to evaluate the effects of early initiation of tofersen.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Medicine, General & Internal

Intravenous edaravone treatment in ALS and survival: An exploratory, retrospective, administrative claims analysis

Benjamin Rix Brooks et al.

Summary: This study evaluated the overall survival of US patients with amyotrophic lateral sclerosis (ALS) treated with intravenous (IV) edaravone compared to those not treated with IV edaravone in a real-world setting. The findings showed that IV edaravone treatment was associated with prolonged overall survival in a large cohort of predominantly riluzole-treated ALS patients in the US.

ECLINICALMEDICINE (2022)

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Article Health Policy & Services

Effects of prolonged interruption of rehabilitation routines in amyotrophic lateral sclerosis patients

Filipe Goncalves et al.

Summary: The study indicates that prolonged interruption of rehabilitation during the lockdown may accelerate the functional decline in ALS patients' motor skills, increase fatigue, and negatively impact quality of life, especially in specific domains.

PALLIATIVE & SUPPORTIVE CARE (2022)

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Article Dentistry, Oral Surgery & Medicine

A case of MuSK antibody-positive myasthenia gravis patient mimicking amyotrophic lateral sclerosis with four videofluoroscopic examinations

Takashi Kasahara et al.

Summary: Patients with MuSK antibody-positive MG may present with bulbar symptoms that can be confused with bulbar-onset ALS. Videofluoroscopic evaluations are helpful in assessing the clinical course of such patients.

ORAL SCIENCE INTERNATIONAL (2022)

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Article Clinical Neurology

Amyotrophic lateral sclerosis with coexisting cancer: a single-center study

Onur Akan et al.

Summary: This study found that 11.6% of ALS patients were associated with cancer. ALS patients with cancer have lower survival rates, and in most cases, cancer is diagnosed before ALS.

ACTA NEUROLOGICA BELGICA (2021)

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Review Clinical Neurology

A systematic review of neuropsychiatric and cognitive assessments used in clinical trials for amyotrophic lateral sclerosis

Emily Beswick et al.

Summary: Up to 50% of ALS patients experience cognitive dysfunction, with high rates of depression and anxiety reported. However, past 25 years of clinical trials have largely neglected the importance of neuropsychiatric symptoms and cognitive impairment in ALS. Evaluation of these non-motor features is crucial for understanding the impact of candidate drugs on all symptoms of ALS.

JOURNAL OF NEUROLOGY (2021)

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Article Clinical Neurology

Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis

Sabrina Paganoni et al.

Summary: In the CENTAUR trial for ALS, orally administered PB-TURSO significantly slowed functional decline and a long-term survival analysis showed that participants receiving PB-TURSO treatment had a median survival 6.5 months longer than those on placebo. These results suggest that PB-TURSO has both functional and survival benefits in ALS.

MUSCLE & NERVE (2021)

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Article Clinical Neurology

Which are the factors influencing NIV adaptation and tolerance in ALS patients?

Massimo Russo et al.

Summary: ALS patients undergoing NIV treatment are affected by respiratory status, behavioral and cognitive impairments which are important factors influencing the adaptation time. Excessive salivation and neurobehavioral disorders are negative predictors of NIV adaptation.

NEUROLOGICAL SCIENCES (2021)

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Review Clinical Neurology

FUS mutation is probably the most common pathogenic gene for JALS, especially sporadic JALS

L. Chen

Summary: In recent years, there has been an increase in reported cases of Juvenile amyotrophic lateral sclerosis (JALS) with Fused in sarcoma (FUS) gene mutations, particularly in sporadic cases. The majority of FUS mutations in JALS occur in the nuclear localization signal (NLS) region, highlighting a potential new focus for diagnosis and treatment research.

REVUE NEUROLOGIQUE (2021)

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Article Toxicology

Results of botulinum toxin therapy for spasticity in patients with amyotrophic lateral sclerosis

Stéphanie Deffontaines Rufin et al.

TOXICON (2021)

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Review Environmental Sciences

Systematic Review of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis over Time

Laura Ortega-Hombrados et al.

Summary: The study found that therapeutic physical exercise can significantly improve the functional abilities of patients with amyotrophic lateral sclerosis (ALS) and help slow down the degeneration of muscles. Participants showed significant improvements in subjective perception and functional capacities in the short, medium and long terms.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Clinical Neurology

Diagnostic Utility of Gold Coast Criteria in Amyotrophic Lateral Sclerosis

Andrew Hannaford et al.

Summary: The study found that the Gold Coast criteria had high sensitivity in the diagnosis of ALS, with consistent accuracy across different subgroups based on disease origin, duration, and functional impairments. In atypical ALS phenotypes, the Gold Coast criteria showed higher sensitivity and specificity.

ANNALS OF NEUROLOGY (2021)

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Article Rehabilitation

A further Rasch analysis of the Fear-Avoidance Beliefs Questionnaire in adults with chronic low back pain suggests the revision of its rating scale

Franco Franchignoni et al.

Summary: This study aimed to examine the psychometric properties of the Fear-Avoidance Beliefs Questionnaire (FABQ) and its two subscales in subjects with chronic low back pain. The results showed that the FABQ-PA and FABQ-W subscales have adequate unidimensionality. Simplifying the response options of both subscales is strongly recommended to improve the technical quality of the scale.

EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE (2021)

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Article Genetics & Heredity

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Wouter van Rheenen et al.

Summary: A cross-ancestry genome-wide association meta-analysis of amyotrophic lateral sclerosis (ALS) identified 15 risk loci with distinct genetic architectures and neuron-specific biology. The study emphasized the urgent need for disease-modifying therapies for ALS. High cholesterol levels were suggested to have a causal role in the onset of ALS, among other environmental and lifestyle risk factors.

NATURE GENETICS (2021)

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Article Clinical Neurology

Assessment of feasibility and utility of universal referral to specialty palliative care in a multidisciplinary amyotrophic lateral sclerosis clinic: A cohort study

Julia Hafer et al.

Summary: This study explores the feasibility and utility of embedding a palliative care physician in an ALS clinic. Within the study period, 75% of patients with ALS were seen by the palliative care physician, with discussions on advance care planning and goals of care. The most common topics discussed were code status and meaning/values.

MUSCLE & NERVE (2021)

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Article Clinical Neurology

Persian adaptation of Edinburgh Cognitive and Behavioural Screen (ECAS)

Helia Mojtabavi et al.

Summary: The Persian version of ECAS shows high internal consistency and strong correlation with MoCA and ALS-FRS, effectively distinguishing between patients and healthy individuals.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2021)

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Review Clinical Neurology

The Safety and Efficacy of Stem Cell Therapy as an Emerging Therapy for ALS: A Systematic Review of Controlled Clinical Trials

Ammar Aljabri et al.

Summary: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with no cure currently available. Stem cell transplantation shows potential in treating ALS, but more properly conducted clinical trials are needed to evaluate its safety and efficacy.

FRONTIERS IN NEUROLOGY (2021)

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Article Clinical Neurology

Targeted sequencing panels in Italian ALS patients support different etiologies in the ALS/FTD continuum

Anna Bartoletti-Stella et al.

Summary: Research suggests that genetic abnormalities in major ALS genes primarily affect patients with a family history of pure ALS, while rare ALS/FTD gene variants are more common in patients with a family history of other neurodegenerative diseases. These two genetic components may help guide genetic screening protocols.

JOURNAL OF NEUROLOGY (2021)

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Article Clinical Neurology

Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes

Francesc Graus et al.

Summary: The updated diagnostic criteria for PNS proposed by a panel of experts involve the classification of high-risk, intermediate-risk, and low-risk phenotypes, as well as the introduction of a new classification of evidence for PNS.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2021)

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Article Cell & Tissue Engineering

Looking backward to move forward: a meta-analysis of stem cell therapy in amyotrophic lateral sclerosis

Cynthia Morata-Tarifa et al.

Summary: A meta-analysis was conducted to evaluate the outcomes of stem cell therapy trials for ALS, indicating a transient positive effect on clinical progression with mesenchymal stem cell intrathecal injection, but a worsening of respiratory function. Further research is needed to determine optimal cell products and administration routes for improved outcomes.

NPJ REGENERATIVE MEDICINE (2021)

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Article Neurosciences

Behavioural changes predict poorer survival in amyotrophic lateral sclerosis

Chilan Nguyen et al.

Summary: The presence of behavioral and cognitive impairments in ALS patients is associated with poor survival outcomes. The MiND-B and ACE inventories are simple and efficient clinical tools that can aid in the prognostication of this patient population in multidisciplinary ALS clinics.

BRAIN AND COGNITION (2021)

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Article Clinical Neurology

Gold Coast diagnostic criteria increase sensitivity in amyotrophic lateral sclerosis

Kirsten Pugdahl et al.

Summary: The study found that the "Gold Coast" diagnostic criteria for ALS had higher sensitivity compared to previous criteria, primarily due to considering PMA as a form of ALS. This simpler criteria can be used in clinical practice and may be included in clinical trials.

CLINICAL NEUROPHYSIOLOGY (2021)

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Review Immunology

A paraneoplastic syndrome misdiagnosed as ALS: What are the red flags? A case report and review of the literature

Assaf Tolkovsky et al.

Summary: This case report highlights a rare case of paraneoplastic motor neuron disease (PMND) with atypical clinical presentation including features such as autonomic dysfunction, sensory disturbance, and cognitive decline. It emphasizes the importance of considering paraneoplastic neurological syndromes in the differential diagnosis, especially when symptoms are not typical for other neurological conditions such as amyotrophic lateral sclerosis (ALS).

JOURNAL OF NEUROIMMUNOLOGY (2021)

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Article Clinical Neurology

Gold Coast diagnostic criteria: Implications for ALS diagnosis and clinical trial enrollment

Steve Vucic et al.

Summary: The diagnostic criteria for ALS have been simplified with the Gold Coast criteria, which have increased sensitivity, maintained accuracy, and differentiated atypical phenotypes. It is proposed that these criteria should be incorporated into routine practice and clinical trial settings.

MUSCLE & NERVE (2021)

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Article Clinical Neurology

Lung volume recruitment improves volitional airway clearance in amyotrophic lateral sclerosis

Stuart Cleary et al.

Summary: This study evaluated the effects of lung volume recruitment treatment (LVR) on volitional airway clearance and protection behaviors in people with ALS. LVR treatment significantly increased maximum expiratory rates during all tested behaviors, with effects lasting up to 30 minutes post-treatment. The findings have implications for patient care, offering control over ALS symptoms and improved respiratory care in low-resource settings.

MUSCLE & NERVE (2021)

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Article Neurosciences

The Gold Coast criteria increases the diagnostic sensitivity for amyotrophic lateral sclerosis in a Chinese population

Dongchao Shen et al.

Summary: The study showed that the Gold Coast criteria had greater diagnostic sensitivity for ALS than the rEEC and Awaji criteria in a Chinese population. The sensitivity remained robust across subgroups, especially in limb-onset ALS patients, indicating its potential for use in clinical practice and future therapeutic trials.

TRANSLATIONAL NEURODEGENERATION (2021)

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Article Neurosciences

Sensitivity of Awaji Criteria and Revised El Escorial Criteria in the Diagnosis of Amyotrophic Lateral Sclerosis (ALS) at First Visit in a Tunisian Cohort

Bademain Jean Fabrice Ido et al.

Summary: The study compared the sensitivities of revised El Escorial criteria (rEEC) and Awaji criteria (AC) in diagnosing definite ALS in a Tunisian hospital cohort. Results showed that AC had significantly higher sensitivity than rEEC in the early diagnosis of ALS, but this difference gradually decreased during disease progression.

NEUROLOGY RESEARCH INTERNATIONAL (2021)

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Letter Clinical Neurology

IgM-gammopathy strongly favours immune treatable MMN and MADSAM over ALS

Shahar Shelly et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2020)

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Article Clinical Neurology

Respiratory function and cognitive profile in amyotrophic lateral sclerosis

W. Huynh et al.

EUROPEAN JOURNAL OF NEUROLOGY (2020)

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Review Clinical Neurology

Global variation in prevalence and incidence of amyotrophic lateral sclerosis: a systematic review and meta-analysis

Lu Xu et al.

JOURNAL OF NEUROLOGY (2020)

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Article Clinical Neurology

Prognostic role of slow vital capacity in amyotrophic lateral sclerosis

Andrea Calvo et al.

JOURNAL OF NEUROLOGY (2020)

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Article Clinical Neurology

ALS phenotype is influenced by age, sex, and genetics: A population-based study

Adriano Chio et al.

NEUROLOGY (2020)

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Article Critical Care Medicine

The Oral Secretion Scale and Prognostic Factors for Survival in Subjects With Amyotrophic Lateral Sclerosis

Pamela A. Cazzolli et al.

RESPIRATORY CARE (2020)

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Article Clinical Neurology

Neuromuscular manifestations of lead poisoning in opium and herbal users in Iran

A. A. Okhovat et al.

REVUE NEUROLOGIQUE (2020)

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Review Rehabilitation

Effects of Exercise in Patients With Amyotrophic Lateral Sclerosis A Systematic Review and Meta-Analysis

Lijiao Meng et al.

AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION (2020)

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Review Clinical Neurology

The Use of Telehealth to Enhance Care in ALS and other Neuromuscular Disorders

Anne Haulman et al.

MUSCLE & NERVE (2020)

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Review Pathology

Common mutations of interest in the diagnosis of amyotrophic lateral sclerosis: how common are common mutations in ALS genes?

Benedetta Perrone et al.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2020)

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Article Medicine, General & Internal

Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

Timothy Miller et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Medicine, General & Internal

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis

Sabrina Paganoni et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Clinical Neurology

Discussing personalized prognosis in amyotrophic lateral sclerosis: development of a communication guide

Remko M. van Eenennaam et al.

BMC NEUROLOGY (2020)

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Article Medicine, General & Internal

Canadian best practice recommendations for the management of amyotrophic lateral sclerosis

Christen Shoesmith et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2020)

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Review Medicine, General & Internal

Magnesium for skeletal muscle cramps

Scott R. Garrison et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2020)

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Article Clinical Neurology

A Case of Cervical Spondylotic Amyotrophy Mimicking Amyotrophic Lateral Sclerosis

Pretty Sara Idiculla et al.

CASE REPORTS IN NEUROLOGY (2020)

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Review Clinical Neurology

Efficacy and safety of mexiletine in amyotrophic lateral sclerosis: a systematic review of randomized controlled trials

Karen Joy B Adiao et al.

NEURODEGENERATIVE DISEASE MANAGEMENT (2020)

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Article Critical Care Medicine

Respiratory Failure in Amyotrophic Lateral Sclerosis

Shannon Niedermeyer et al.

CHEST (2019)

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Review Clinical Neurology

Kennedy's disease (spinal and bulbar muscular atrophy): a clinically oriented review of a rare disease

Marianthi Breza et al.

JOURNAL OF NEUROLOGY (2019)

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Review Medicine, General & Internal

Motor Neuron Disease: Pathophysiology, Diagnosis, and Management

Laura A. Foster et al.

AMERICAN JOURNAL OF MEDICINE (2019)

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Article Clinical Neurology

Diagnostic criteria for amyotrophic lateral sclerosis: A multicentre study of inter-rater variation and sensitivity

B. Johnsen et al.

CLINICAL NEUROPHYSIOLOGY (2019)

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Article Clinical Neurology

Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Nilo Riva et al.

LANCET NEUROLOGY (2019)

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Article Radiology, Nuclear Medicine & Medical Imaging

Amyotrophic Lateral Sclerosis versus Multifocal Motor Neuropathy: Utility of MR Neurography

Moritz Kronlage et al.

RADIOLOGY (2019)

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Review Clinical Neurology

Epidemiology of amyotrophic lateral sclerosis: an update of recent literature

Elisa Longinetti et al.

CURRENT OPINION IN NEUROLOGY (2019)

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Article Clinical Neurology

Nutritional prognostic factors for survival in amyotrophic lateral sclerosis patients undergone percutaneous endoscopic gastrostomy placement

Michele Barone et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2019)

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Article Clinical Neurology

Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis

Marie Ryan et al.

JAMA NEUROLOGY (2019)

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Article Neurosciences

A Comprehensive Examination of Percutaneous Endoscopic Gastrostomy and Its Association with Amyotrophic Lateral Sclerosis Patient Outcomes

Leila Bond et al.

BRAIN SCIENCES (2019)

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Article Clinical Neurology

Provisional best practices guidelines for the evaluation of bulbar dysfunction in amyotrophic lateral sclerosis

Gary L. Pattee et al.

MUSCLE & NERVE (2019)

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Review Clinical Neurology

Efficacy and safety of edaravone in treatment of amyotrophic lateral sclerosisa systematic review and meta-analysis

Linting Luo et al.

NEUROLOGICAL SCIENCES (2019)

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Review Clinical Neurology

Screening for cognitive and behavioral change in amyotrophic lateral sclerosis/motor neuron disease: a systematic review of validated screening methods

Natalie Simon et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2019)

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Article Medicine, General & Internal

Subacute combined degeneration of the spinal cord masking motor neuron disease: a case report

Paula Loveland et al.

JOURNAL OF MEDICAL CASE REPORTS (2019)

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Review Clinical Neurology

Tracheostomy in motor neurone disease

Martin R. Turner et al.

PRACTICAL NEUROLOGY (2019)

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Article Clinical Neurology

IMPROVING SYMPTOM MANAGEMENT FOR PEOPLE WITH AMYOTROPHIC LATERAL SCLEROSIS

Katharine Nicholson et al.

MUSCLE & NERVE (2018)

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Review Health Care Sciences & Services

Caregiver burden in amyotrophic lateral sclerosis: A systematic review

Jessica de Wit et al.

PALLIATIVE MEDICINE (2018)

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Article Audiology & Speech-Language Pathology

Speech deterioration in amyotrophic lateral sclerosis (ALS) after manifestation of bulbar symptoms

Tanja Makkonen et al.

INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS (2018)

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Review Clinical Neurology

Nutrition management methods effective in increasing weight, survival time and functional status in ALS patients: a systematic review

Jaylin Kellogg et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2018)

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Article Nutrition & Dietetics

ESPEN guideline clinical nutrition in neurology

Rosa Burgos et al.

CLINICAL NUTRITION (2018)

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Article Clinical Neurology

Impact of an early respiratory care programme with non-invasive ventilation adaptation in patients with amyotrophic lateral sclerosis

M. Vitacca et al.

EUROPEAN JOURNAL OF NEUROLOGY (2018)

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Review Clinical Neurology

Neuroimaging in amyotrophic lateral sclerosis: current and emerging uses

Federica Agosta et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2018)

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Article Clinical Neurology

Motor neuron disease of paraneoplastic origin: a rare but treatable condition

Nicolas Mele et al.

JOURNAL OF NEUROLOGY (2018)

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Article Clinical Neurology

MOTOR UNIT NUMBER INDEX AND NEUROPHYSIOLOGICAL INDEX AS CANDIDATE BIOMARKERS OF PRESYMPTOMATIC MOTOR NEURON LOSS IN AMYOTROPHIC LATERAL SCLEROSIS

Marcio Luiz Escorcio-Bezerra et al.

MUSCLE & NERVE (2018)

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Article Nutrition & Dietetics

Influence of a multidisciplinary protocol on nutritional status at diagnosis in amyotrophic lateral sclerosis

Juan Jose Lopez-Gomez et al.

NUTRITION (2018)

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Review Clinical Neurology

Neuroimaging in amyotrophic lateral sclerosis: current and emerging uses

Federica Agosta et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2018)

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Article Clinical Neurology

Associative Increases in Amyotrophic Lateral Sclerosis Survival Duration With Non-invasive Ventilation Initiation and Usage Protocols

Nishad Khamankar et al.

FRONTIERS IN NEUROLOGY (2018)

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Editorial Material Orthopedics

Clinimetrics: Amyotrophic Lateral Sclerosis Functional Rating Scale-revised (ALSFRS-R)

Michael Lee et al.

JOURNAL OF PHYSIOTHERAPY (2018)

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Review Clinical Neurology

Physical therapy for individuals with amyotrophic lateral sclerosis: current insights

Vanina Dal Bello-Haas

DEGENERATIVE NEUROLOGICAL AND NEUROMUSCULAR DISEASE (2018)

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Review Medicine, General & Internal

Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease

Chris Gibbons et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)

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Letter Clinical Neurology

Sialorrhoea and reversals in ALS functional rating scale

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JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)

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Article Clinical Neurology

What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis

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JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)

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Article Clinical Neurology

Hypoparathyroidism: A rare mimic of amyotrophic lateral sclerosis

Haris Hakeem et al.

MUSCLE & NERVE (2017)

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Article Clinical Neurology

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis

Alexander J. Mcgeachan et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Article Clinical Neurology

Meditation training for people with amyotrophic lateral sclerosis: a randomized clinical trial

F. Pagnini et al.

EUROPEAN JOURNAL OF NEUROLOGY (2017)

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Article Clinical Neurology

Comorbidity of dementia with amyotrophic lateral sclerosis (ALS): insights from a large multicenter Italian cohort

Francesca Trojsi et al.

JOURNAL OF NEUROLOGY (2017)

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Review Clinical Neurology

Pain in amyotrophic lateral sclerosis

Adriano Chio et al.

LANCET NEUROLOGY (2017)

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Article Clinical Neurology

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Koji Abe et al.

LANCET NEUROLOGY (2017)

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Article Medicine, General & Internal

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

R. S. Finkel et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

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Article Clinical Neurology

Decision-making for tracheostomy in amyotrophic lateral sclerosis (ALS): a retrospective study

Piero Ceriana et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Article Clinical Neurology

Post-hoc analysis of MCI186-17, the extension study to MCI186-16, the confiratory double-blind, parallel-group, placebo-controlled study of edaravone in amyotrophic lateral sclerosis

Fumihiro Takahashi et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Article Clinical Neurology

A safety analysis of edaravone (MCI-186) during the first six cycles (24 weeks) of amyotrophic lateral sclerosis (ALS) therapy from the double-blind period in three randomized, placebo-controlled studies

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AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Article Clinical Neurology

The evaluation of bulbar dysfunction in amyotrophic lateral sclerosis: survey of clinical practice patterns in the United States

Emily K. Plowman et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Article Clinical Neurology

Ability of pulmonary function decline to predict death in amyotrophic lateral sclerosis patients

Irina Enache et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Review Clinical Neurology

Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria

Michael J. Strong et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2017)

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Article Medicine, General & Internal

Amyotrophic lateral sclerosis

Orla Hardiman et al.

NATURE REVIEWS DISEASE PRIMERS (2017)

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Article Multidisciplinary Sciences

The Awaji criteria increases the diagnostic sensitivity of the revised El Escorial criteria for amyotrophic lateral sclerosis diagnosis in a Chinese population

Da-Wei Li et al.

PLOS ONE (2017)

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Article Multidisciplinary Sciences

The path to specialist multidisciplinary care in amyotrophic lateral sclerosis: A population-based study of consultations, interventions and costs

Miriam Galvin et al.

PLOS ONE (2017)

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Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease

A. Radunovic et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

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Article Clinical Neurology

Physician perceptions about living organ donation in patients with Amyotrophic Lateral Sclerosis

S. Ansari et al.

CLINICAL NEUROLOGY AND NEUROSURGERY (2017)

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Article Respiratory System

The predictive value of respiratory function tests for non-invasive ventilation in amyotrophic lateral sclerosis

T. B. M. Tilanus et al.

RESPIRATORY RESEARCH (2017)

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Article Clinical Neurology

Motor Unit Number Index (MUNIX) detects motor neuron loss in pre-symptomatic muscles in Amyotrophic Lateral Sclerosis

Christoph Neuwirth et al.

CLINICAL NEUROPHYSIOLOGY (2017)

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Review Medicine, General & Internal

Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease

Louisa Ng et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

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Clinical and demographic factors and outcome of amyotrophic lateral sclerosis in relation to population ancestral origin

Benoit Marin et al.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2016)

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Article Clinical Neurology

Pseudobulbar affect (PBA) in an incident ALS cohort: results from the Apulia registry (SLAP)

Rosanna Tortelli et al.

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Review Medicine, Research & Experimental

The Role of Radiation Therapy in the Management of Sialorrhea: A Systematic Review

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LARYNGOSCOPE (2016)

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Article Gastroenterology & Hepatology

Discriminant ability of the Eating Assessment Tool-10 to detect aspiration in individuals with amyotrophic lateral sclerosis

E. K. Plowman et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2016)

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Article Clinical Neurology

Item response theory analysis of the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised in the Pooled Resource Open-Access ALS Clinical Trials Database

Elizabeth D. Bacci et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2016)

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Review Clinical Neurology

Awaji criteria improves the diagnostic sensitivity in amyotrophic lateral sclerosis: A systematic review using individual patient data

Nimeshan Geevasinga et al.

CLINICAL NEUROPHYSIOLOGY (2016)

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Article Clinical Neurology

Intraspinal delivery of bone marrow stromal cell-derived neural stem cells in patients with amyotrophic lateral sclerosis: A safety and feasibility study

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JOURNAL OF THE NEUROLOGICAL SCIENCES (2016)

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Myasthenia gravis with muscle specific kinase antibodies mimicking amyotrophic lateral sclerosis

Maartje G. Huijbers et al.

NEUROMUSCULAR DISORDERS (2016)

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Article Multidisciplinary Sciences

Projected increase in amyotrophic lateral sclerosis from 2015 to 2040

Karissa C. Arthur et al.

NATURE COMMUNICATIONS (2016)

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Article Audiology & Speech-Language Pathology

Oral motor functions, speech and communication before a definitive diagnosis of amyotrophic lateral sclerosis

Tanja Makkonen et al.

JOURNAL OF COMMUNICATION DISORDERS (2016)

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Article Clinical Neurology

Demographic and clinical features of ALS in northeastern Iran from March 2007 through March 2013; A case series study

Reza Boostani et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2016)

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Article Health Care Sciences & Services

Family caregivers' accounts of caring for a family member with motor neurone disease in Norway: a qualitative study

Sverre Vigeland Lerum et al.

BMC PALLIATIVE CARE (2016)

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Article Medicine, General & Internal

Noninvasive ventilation in amyotrophic lateral sclerosis: effects on sleep quality and quality of life

Eva Vandoorne et al.

ACTA CLINICA BELGICA (2016)

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Editorial Material Clinical Neurology

Characterization of monoclonal gammopathy in patients with amyotrophic lateral sclerosis

H. -H. Wolf et al.

ACTA NEUROLOGICA SCANDINAVICA (2015)

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Article Health Care Sciences & Services

Patient journey to a specialist amyotrophic lateral sclerosis multidisciplinary clinic: an exploratory study

M. Galvin et al.

BMC HEALTH SERVICES RESEARCH (2015)

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Article Medicine, General & Internal

Anti-MuSK Antibody-positive Myasthenia Gravis Mimicking Amyotrophic Lateral Sclerosis

Natsumi Furuta et al.

INTERNAL MEDICINE (2015)

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Article Clinical Neurology

Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study

Christopher J. McDermott et al.

LANCET NEUROLOGY (2015)

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Review Audiology & Speech-Language Pathology

Is There a Role for Exercise in the Management of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis?

Emily K. Plowman

JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH (2015)

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Amyotrophic lateral sclerosis progression: Iran-ALS clinical registry, a multicentre study

Hosein Shamshiri et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2015)

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Article Clinical Neurology

Validation of the Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen (ECAS): A cognitive tool for motor disorders

Elaine Niven et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2015)

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Cognitive behavioural therapy and quality of life in psychologically distressed patients with amyotrophic lateral sclerosis and their caregivers: Results of a prematurely stopped randomized controlled trial

Annerieke C. Van Groenestijn et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2015)

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Article Clinical Neurology

Development and evaluation of a clinical staging system for amyotrophic lateral sclerosis

Adriano Chio et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2015)

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Article Clinical Neurology

Cognitive correlates in amyotrophic lateral sclerosis: a population-based study in Italy

Anna Montuschi et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2015)

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Cognitive Impairment in Chinese Patients with Sporadic Amyotrophic Lateral Sclerosis

Bo Cui et al.

PLOS ONE (2015)

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Review Critical Care Medicine

A Review of Options for Treating Sialorrhea in Amyotrophic Lateral Sclerosis

Paolo Banfi et al.

RESPIRATORY CARE (2015)

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Dysarthria and dysphagia in Amyotrophic Lateral Sclerosis with spinal onset: A study of quality of life related to swallowing

Andressa da Costa Franceschini et al.

NEUROREHABILITATION (2015)

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Review Medicine, General & Internal

Percutaneous endoscopic gastrostomy versus nasogastric tube feeding for adults with swallowing disturbances

Claudio A. R. Gomes et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)

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Review Medicine, General & Internal

Quinine for muscle cramps

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COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)

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Review Neurosciences

Dissection of genetic factors associated with amyotrophic lateral sclerosis

Claire S. Leblond et al.

EXPERIMENTAL NEUROLOGY (2014)

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Editorial Material Clinical Neurology

Tracheostomy ventilation in ALS: A Japanese bias

Andrea Vianello et al.

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Rehabilitation in amyotrophic lateral sclerosis: Why it matters

Salony Majmudar et al.

MUSCLE & NERVE (2014)

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GENETIC HETEROGENEITY OF AMYOTROPHIC LATERAL SCLEROSIS: IMPLICATIONS FOR CLINICAL PRACTICE AND RESEARCH

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MUSCLE & NERVE (2014)

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Article Geriatrics & Gerontology

Repeat expansion in C9ORF72 is not a major cause of amyotrophic lateral sclerosis among Iranian patients

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NEUROBIOLOGY OF AGING (2014)

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Review Cell & Tissue Engineering

Concise Review: Stem Cell Therapies for Amyotrophic Lateral Sclerosis: Recent Advances and Prospects for the Future

J. Simon Lunn et al.

STEM CELLS (2014)

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Screening for cognition and behaviour changes in ALS

Sharon Abrahams et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2014)

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Article Clinical Neurology

Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients

Koji Abe et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2014)

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Estimating clinical stage of amyotrophic lateral sclerosis from the ALS Functional Rating Scale

Rubika Balendra et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2014)

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A commonly overlooked motor neuron disease mimicker

Manas Ghosh et al.

ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS (2014)

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Review Clinical Neurology

Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect

Kerri A. Schoedel et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2014)

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Evidence of multidimensionality in the ALSFRS- R Scale: a critical appraisal on its measurement properties using Rasch analysis

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Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial

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Article Biotechnology & Applied Microbiology

Synergistic Effects of GDNF and VEGF on Lifespan and Disease Progression in a Familial ALS Rat Model

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MOLECULAR THERAPY (2013)

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Article Geriatrics & Gerontology

Genetic analysis and SOD1 mutation screening in Iranian amyotrophic lateral sclerosis patients

Afagh Alavi et al.

NEUROBIOLOGY OF AGING (2013)

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SYSTEMIC TREATMENT WITH ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AMELIORATES CLINICAL AND PATHOLOGICAL FEATURES IN THE AMYOTROPHIC LATERAL SCLEROSIS MURINE MODEL

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NEUROSCIENCE (2013)

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Dysphagia in Stroke, Neurodegenerative Disease, and Advanced Dementia

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OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA (2013)

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Nocturnal Hypoxia in ALS Is Related to Cognitive Dysfunction and Can Occur as Clusters of Desaturations

Su-Yeon Park et al.

PLOS ONE (2013)

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Prevalence and characteristics of pain in early and late stages of ALS

Itza Rivera et al.

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2013)

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Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease

Johannes Brettschneider et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2013)

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Editorial Material Medicine, General & Internal

Lead Poisoning Mimicking Amyotrophic Lateral Sclerosis: An Adverse Effect of Rituals

Claude Bachmeyer et al.

AMERICAN JOURNAL OF MEDICINE (2012)

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A proposed staging system for amyotrophic lateral sclerosis

Jose C. Roche et al.

BRAIN (2012)

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EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) - revised report of an EFNS task force

Peter M. Andersen et al.

EUROPEAN JOURNAL OF NEUROLOGY (2012)

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Correction Clinical Neurology

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study (vol 11, pg 232, 2012)

S. Byrne et al.

LANCET NEUROLOGY (2012)

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Review Clinical Neurology

Respiratory therapies for amyotrophic lateral sclerosis: A primer

Kirsten L. Gruis et al.

MUSCLE & NERVE (2012)

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Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

Robert G. Miller et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2012)

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Article Clinical Neurology

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study

Susan Byrne et al.

LANCET NEUROLOGY (2012)

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Article Clinical Neurology

A comparison of assisted cough techniques in stable patients with severe respiratory insufficiency due to amyotrophic lateral sclerosis

Cristina Senent et al.

AMYOTROPHIC LATERAL SCLEROSIS (2011)

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Review Nutrition & Dietetics

Nutritional state, energy intakes and energy expenditure of amyotrophic lateral sclerosis (ALS) patients

L. Genton et al.

CLINICAL NUTRITION (2011)

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Review Clinical Neurology

Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments

Ariel Miller et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2011)

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Botulinum Toxin A Versus B in Sialorrhea: A Prospective, Randomized, Double-Blind, Crossover Pilot Study in Patients with Amyotrophic Lateral Sclerosis or Parkinson's Disease

Arianna Guidubaldi et al.

MOVEMENT DISORDERS (2011)

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Executive dysfunction is a negative prognostic indicator in patients with ALS without dementia

M. Elamin et al.

NEUROLOGY (2011)

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Dual transplantation of human neural stem cells into cervical and lumbar cord ameliorates motor neuron disease in SOD1 transgenic rats

Leyan Xu et al.

NEUROSCIENCE LETTERS (2011)

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Article Multidisciplinary Sciences

Capnography for Assessing Nocturnal Hypoventilation and Predicting Compliance with Subsequent Noninvasive Ventilation in Patients with ALS

Sung-Min Kim et al.

PLOS ONE (2011)

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Article Clinical Neurology

Detecting frontotemporal dysfunction in ALS: Utility of the ALS Cognitive Behavioral Screen (ALS-CBS™)

Susan C. Woolley et al.

AMYOTROPHIC LATERAL SCLEROSIS (2010)

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Review Clinical Neurology

Dysarthria in amyotrophic lateral sclerosis: A review

Barbara Tomik et al.

AMYOTROPHIC LATERAL SCLEROSIS (2010)

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Epidemiology of amyotrophic lateral sclerosis in Isfahan, Iran

M. Sajjadi et al.

EUROPEAN JOURNAL OF NEUROLOGY (2010)

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Article Clinical Neurology

EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision

N. Attal et al.

EUROPEAN JOURNAL OF NEUROLOGY (2010)

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Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord

Sharyn L. Rossi et al.

PLOS ONE (2010)

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Article Clinical Neurology

Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease

Richard S. Bedlack et al.

AMYOTROPHIC LATERAL SCLEROSIS (2009)

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Review Clinical Neurology

Prognostic factors in ALS: A critical review

Adriano Chio et al.

AMYOTROPHIC LATERAL SCLEROSIS (2009)

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Familial Aggregation of Amyotrophic Lateral Sclerosis

Fang Fang et al.

ANNALS OF NEUROLOGY (2009)

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LATE-ONSET HEXOSAMINIDASE A DEFICIENCY MIMICKING PRIMARY LATERAL SCLEROSIS

Clecio Godeiro-Junior et al.

ARQUIVOS DE NEURO-PSIQUIATRIA (2009)

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Human Neural Stem Cell Grafts in the Spinal Cord of SOD1 Transgenic Rats: Differentiation and Structural Integration into the Segmental Motor Circuitry

Leyan Xu et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2009)

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Review Health Care Sciences & Services

Systematic Review of the Effectiveness of Botulinum Toxin or Radiotherapy for Sialorrhea in Patients with Amyotrophic Lateral Sclerosis

Carol A. Stone et al.

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2009)

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Review Clinical Neurology

Practice Parameter update: The care of the patient with amyotrophic lateral sclerosis: Multidisciplinary care, symptom management, and cognitive/behavioral impairment (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology

R. G. Miller et al.

NEUROLOGY (2009)

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Review Clinical Neurology

A Systematic Review of the Effect of Moderate Intensity Exercise on Function and Disease Progression in Amyotrophic Lateral Sclerosis

Andrew J. Lui et al.

JOURNAL OF NEUROLOGIC PHYSICAL THERAPY (2009)

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Review Medicine, General & Internal

Multidisciplinary care for adults with amyotrophic lateral sclerosis or motor neuron disease

Louisa Ng et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2009)

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Review Clinical Neurology

Creatine monohydrate in ALS: Effects on strength, fatigue, respiratory status and ALSFRS

Jeffrey Rosenfeld et al.

AMYOTROPHIC LATERAL SCLEROSIS (2008)

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Review Clinical Neurology

Electrodiagnostic criteria for diagnosis of ALS

Mamede de Carvalho et al.

CLINICAL NEUROPHYSIOLOGY (2008)

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Article Clinical Neurology

ALSFRS-R score and its ratio: A useful predictor for ALS-progression

Katja Kollewe et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)

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Article Biotechnology & Applied Microbiology

Direct Muscle Delivery of GDNF With Human Mesenchymal Stem Cells Improves Motor Neuron Survival and Function in a Rat Model of Familial ALS

Masatoshi Suzuki et al.

MOLECULAR THERAPY (2008)

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Article Clinical Neurology

A longitudinal study on quality of life and depression in ALS patient-caregiver couples

A. Gauthier et al.

NEUROLOGY (2007)

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Article Medicine, General & Internal

Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord

Jun Yan et al.

PLOS MEDICINE (2007)

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Article Clinical Neurology

Excellent inter-rater, intra-rater, and telephone-administered reliability of the ALSFRS-R in a multicenter clinical trial

Petra Kaufmann et al.

AMYOTROPHIC LATERAL SCLEROSIS (2007)

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Article Clinical Neurology

Early use of non-invasive ventilation prolongs survival in subjects with ALS

Noah Lechtzin et al.

AMYOTROPHIC LATERAL SCLEROSIS (2007)

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Article Neurosciences

Motor unit number estimation (mune) as a quantitative measure of disease progression and motor unit reorganization in amyotrophic lateral sclerosis

F. Sartucci et al.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2007)

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Preliminary findings: Behavioral worsening on donepezil in patients with frontotemporal dementia

Mario F. Mendez et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2007)

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Article Clinical Neurology

Caregiver time use in ALS

A. Chio et al.

NEUROLOGY (2006)

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Article Clinical Neurology

Predictors and course of elective long-term mechanical ventilation: A prospective study of ALS patients

Judith G. Rabkin et al.

AMYOTROPHIC LATERAL SCLEROSIS (2006)

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Article Clinical Neurology

Progression rate of ALSFRS-R at time of diagnosis predicts survival time in ALS

F Kimura et al.

NEUROLOGY (2006)

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Review Clinical Neurology

Muscle cramps

TM Miller et al.

MUSCLE & NERVE (2005)

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Prevalence and patterns of cognitive impairment in sporadic ALS

GM Ringholz et al.

NEUROLOGY (2005)

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Article Neurosciences

Primary hyperparathyroidism simulating motor neuron disease:: Case report

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