4.8 Article

Improvement of cognitive function in wild-type and Alzheimer's disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

The Therapeutic Prospects of Targeting IL-1R1 for the Modulation of Neuroinflammation in Central Nervous System Disorders

Joao P. Luis et al.

Summary: IL-1R1 plays a crucial role in the immune system and is closely related to the pathogenesis of various CNS diseases. Blocking IL-1R1 signaling can reduce neuroinflammation and delay disease progression, making it a promising target for the development of treatments for CNS diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Clinical Neurology

Reorganizing brain structure through olfactory training in post-traumatic smell impairment: An MRI study

Abolhasan Rezaeyan et al.

Summary: This study investigates the effects of olfactory training on olfactory function and brain structure in patients with post-traumatic olfactory dysfunction (PTOD). The results show that both classical olfactory training and modified olfactory training can improve olfactory function, and the improvement is associated with changes in the structure of olfactory processing areas in the brain.

JOURNAL OF NEURORADIOLOGY (2022)

Review Neurosciences

Why Do Levels Of Anti-inflammatory Cytokines Increase During Memory Acquisition?

Sergey G. Levin et al.

Summary: Anti-inflammatory cytokines play a protective role in learning and memory in the brain, supporting information processing by optimizing neuronal circuit functioning. They also influence neuroplasticity, neurogenesis, and regulation of the neurovascular unit.

NEUROSCIENCE (2021)

Article Geriatrics & Gerontology

Olfactory Characterization and Training in Older Adults: Protocol Study

Fabiola Zambom-Ferraresi et al.

Summary: This study aims to assess the olfactory function in very old adults and the effect of intervention based on olfactory training. A total of 180 older adults will be recruited from different environments and divided into three groups for evaluation and intervention. The primary endpoint is the change in olfactory capacity after a 12-week intervention, with secondary endpoints including cognitive tasks, quality of life, mood, immune status, and functional capacity.

FRONTIERS IN AGING NEUROSCIENCE (2021)

Review Cell Biology

Modulation of olfactory signal detection in the olfactory epithelium: focus on the internal and external environment, and the emerging role of the immune system

Bertrand Bryche et al.

Summary: The olfactory system is crucial for animal survival as it detects and discriminates odorants in an ever-changing environment. Internal signals such as hormones and neurotransmitters directly affect the activity of olfactory neurons, while the olfactory epithelium interacts with the immune system leading to neuroimmune modulations. Olfactory neurons are exposed to environmental toxicants and pathogens, highlighting the importance of immune cells in the functioning of the olfactory epithelium.

CELL AND TISSUE RESEARCH (2021)

Article Psychiatry

Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease

Natalia M. Lyra e Silva et al.

Summary: Alzheimer's disease is associated with cognitive impairment and metabolic alterations, with mounting evidence suggesting that abnormal signaling in a brain-periphery metabolic axis plays a crucial role in its pathophysiology. The IL-6 pathway may serve as a key link between memory dysfunction and metabolic changes in AD. Targeting pro-inflammatory IL-6 signaling could be a strategy to alleviate memory impairment and metabolic alterations in the disease.

TRANSLATIONAL PSYCHIATRY (2021)

Review Veterinary Sciences

The olfactory system: the remote-sensing arm of the immune system

Ian Tizard et al.

Summary: Odors can influence behaviors in animals, transmit important information such as attracting or repelling disease vectors and predators, recognizing family members and partners, and playing a crucial role in mate selection.

ANIMAL HEALTH RESEARCH REVIEWS (2021)

Review Immunology

Neuromodulation by the immune system: a focus on cytokines

Andrea Francesca Salvador et al.

Summary: Interactions between the immune system and the nervous system play a crucial role in shaping host behavior and nervous system function. These interactions may have evolved to maximize an organism's ability to respond to environmental threats. The immune system relays information to the nervous system through cytokine signaling, and the brain may be hardwired to process information from the immune system in a specific way.

NATURE REVIEWS IMMUNOLOGY (2021)

Review Neurosciences

PLA2G4E, a candidate gene for resilience in Alzheimer's disease and a new target for dementia treatment

Marta Perez-Gonzalez et al.

PROGRESS IN NEUROBIOLOGY (2020)

Article Neurosciences

Smell training improves olfactory function and alters brain structure

Syrina Al Ain et al.

NEUROIMAGE (2019)

Review Neurosciences

Role of the Immune System in the Development of the Central Nervous System

Keiko Morimoto et al.

FRONTIERS IN NEUROSCIENCE (2019)

Review Neurosciences

The role of regulatory T cells in nervous system pathologies

Samuel S. Duffy et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2018)

Review Neurosciences

Neuro-Immune Hemostasis: Homeostasis and Diseases in the Central Nervous System

Ciro de Luca et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Article Clinical Neurology

Cerebral autoinflammatory disease treated with anakinra

Yoonhyuk Jang et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2018)

Article Chemistry, Analytical

Olfactory Dysfunction as a Global Biomarker for Sniffing out Alzheimer's Disease: A Meta-Analysis

Alisha M. Kotecha et al.

BIOSENSORS-BASEL (2018)

Article Clinical Neurology

Regulatory T cells delay disease progression in Alzheimer-like pathology

Cira Dansokho et al.

Article Biochemistry & Molecular Biology

Neuroinflammation: the devil is in the details

Damon J. DiSabato et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Article Multidisciplinary Sciences

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

Anthony J. Filiano et al.

NATURE (2016)

Article Psychiatry

Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance

S. Monteiro et al.

TRANSLATIONAL PSYCHIATRY (2016)

Article Multidisciplinary Sciences

Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer's disease pathology

Kuti Baruch et al.

NATURE COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

IFN-γ and TNF-α Are Involved During Alzheimer Disease Progression and Correlate with Nitric Oxide Production: A Study in Algerian Patients

Mourad Belkhelfa et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2014)

Article Neurosciences

Single App knock-in mouse models of Alzheimer's disease

Takashi Saito et al.

NATURE NEUROSCIENCE (2014)

Article Neurosciences

IFN-γ differentially modulates memory-related processes under basal and chronic stressor conditions

Darcy Litteljohn et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2014)

Article Psychology, Multidisciplinary

A pleasant familiar odor influences perceived stress and peripheral nervous system activity during normal aging

Pauline Joussain et al.

FRONTIERS IN PSYCHOLOGY (2014)

Article Psychology, Clinical

Odor Identification Deficit Predicts Clinical Conversion from Mild Cognitive Impairment to Dementia Due to Alzheimer's Disease

Marta Zaffira Conti et al.

ARCHIVES OF CLINICAL NEUROPSYCHOLOGY (2013)

Review Neurosciences

Learning and memory ... and the immune system

Ioana Marin et al.

LEARNING & MEMORY (2013)

Article Multidisciplinary Sciences

Brain-Immune Interaction Accompanying Odor-Evoked Autobiographic Memory

Masahiro Matsunaga et al.

PLOS ONE (2013)

Article Geriatrics & Gerontology

Interleukin-6 and Memory Functions of Encoding and Recall in Healthy and Depressed Elderly Adults

Virginia Elderkin-Thompson et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2012)

Article Biotechnology & Applied Microbiology

Vaccine for the mind Immunity against self at the choroid plexus for erasing biochemical consequences of stressful episodes

Michal Schwartz et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2012)

Article Immunology

Immune modulation of learning, memory, neural plasticity and neurogenesis

Raz Yirmiya et al.

BRAIN BEHAVIOR AND IMMUNITY (2011)

Article Pharmacology & Pharmacy

Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease

M. Cuadrado-Tejedor et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Article Neurosciences

Olfactory deficit detected by fMRI in early Alzheimer's disease

Jianli Wang et al.

BRAIN RESEARCH (2010)

Review Neurosciences

Interleukin-1β with learning and memory

Zhen-Bo Huang et al.

NEUROSCIENCE BULLETIN (2010)

Article Geriatrics & Gerontology

Increased Serum IL-1 beta Level in Alzheimer's Disease and Mild Cognitive Impairment

Orestes Vicente Forlenza et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2009)

Editorial Material Medicine, General & Internal

Cool with Plaques and Tangles

Douglas C. Ewbank et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Immunology

Adaptive immunity affects learning behavior in mice

Anna Brynskikh et al.

BRAIN BEHAVIOR AND IMMUNITY (2008)

Review Biochemistry & Molecular Biology

Regulatory T cells and immune tolerance

Shimon Sakaguchi et al.

Article Pharmacology & Pharmacy

Impairment of recognition memory in interleukin-6 knock-out mice

Anna Hryniewicz et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2007)

Article Immunology

Systemic infections and inflammation affect chronic neurodegeneration

V. Hugh Perry et al.

NATURE REVIEWS IMMUNOLOGY (2007)

Article Immunology

To smell the immune system: Olfaction, autoimmunity and brain involvement

Rael D. Strous et al.

AUTOIMMUNITY REVIEWS (2006)

Article Biochemistry & Molecular Biology

Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

Rebecca Radde et al.

EMBO REPORTS (2006)

Article Immunology

Interleukin-1 mediates Alzheimer and Lewy body pathologies

W. Sue T. Griffin et al.

JOURNAL OF NEUROINFLAMMATION (2006)

Review Behavioral Sciences

The olfactory bulbectomised rat as a model of depression

C Song et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2005)

Article Multidisciplinary Sciences

T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

J Kipnis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Dermatology

Mitigation of stress-induced suppression of contact hypersensitivity by odorant inhalation

J Hosoi et al.

BRITISH JOURNAL OF DERMATOLOGY (2001)

Review Neurosciences

Interleukin I in the brain: biology, pathology and therapeutic target

NJ Rothwell et al.

TRENDS IN NEUROSCIENCES (2000)