期刊
APPLIED SCIENCES-BASEL
卷 13, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/app13084936
关键词
particulate matter 2; 5; vascular endothelial function; flow-mediated dilation; aerobic exercise
This study aimed to compare the vascular responses to moderate-intensity treadmill running in high PM2.5 (HPM2.5) and low PM2.5 (LPM2.5) conditions in healthy young males. The results showed that acute PM2.5 exposure can counteract the positive effect of aerobic exercise on vascular endothelial function in young males.
Particulate matter 2.5 (PM2.5) is an environmental pollutant linked with the risk of cardiovascular disease. Aerobic exercise performed in polluted environments may have fewer benefits because of increased PM2.5 inhalation during exercise. However, the vascular responses to aerobic exercise in high PM2.5 (HPM2.5) conditions remain unknown. This study aimed to examine the acute flow-mediated dilation (FMD) response to moderate-intensity treadmill running in HPM2.5 levels compared to low PM2.5 (LPM2.5) levels in healthy young males. Treadmill running in both HPM2.5 and LPM2.5 levels was completed by nine subjects. Brachial artery FMD was measured before and after the exercise to assess vascular endothelial function. Indoor PM2.5 concentration was significantly higher in HPM2.5 than in LPM2.5 conditions (p < 0.001). Scaled FMD significantly increased after the exercise in LPM2.5 conditions but not in HPM2.5 (p = 0.03), and baseline diameter increased only in HPM2.5 conditions after the exercise (p = 0.001). Baseline diameter and peak diameter were smaller, and time to peak dilation was delayed in HPM2.5 compared to LPM2.5 in pre-exercise intervention measurements (p < 0.05). Therefore, acute PM2.5 exposure can counteract the positive effect of aerobic exercise on vascular endothelial function in young males.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据