Hepatoprotective and nephroprotective effects of Sedum adenotrichum in paracetamol-induced hepatotoxicity in rabbits

Article Chemistry, Multidisciplinary

Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats

Erdi Onur Gokkaya et al.

Summary: The study demonstrated that resveratrol and avocado oil have protective effects against paracetamol-induced hepatotoxicity in rats by reducing oxidative stress, DNA damage, and promoting antioxidant status.

DRUG AND CHEMICAL TOXICOLOGY (2022)

添加到收藏夹

Review Chemistry, Medicinal

Profile of herbal and dietary supplements induced liver injury in Latin America: A systematic review of published reports

Genario Santos et al.

Summary: This study reviewed the clinical features of HDS-related hepatotoxicity in LA region, with Centella asiatica, Carthamus tinctorius, and Herbalife (R) being the most reported culprit products. The clinical characteristics of HDS hepatotoxicity in LA were found to be similar to those in the USA, Europe, and China, with predominance of young females, hepatocellular damage, high rate of acute liver failure and mortality, more frequent inadvertent re-challenge, and chronic damage.

PHYTOTHERAPY RESEARCH (2021)

添加到收藏夹

Article

Protective potential of Cynara scolymus extract in thioacetamide model of hepatic injury in rats

Deena El-Deberky et al.

Revista Bionatura (2021)

添加到收藏夹

Article Environmental Sciences

Toxicological effects of deltamethrin on quail cerebrum: Weakened antioxidant defense and enhanced apoptosis

Jiayi Li et al.

Summary: Chronic exposure to deltamethrin induces inflammation and apoptosis in quail cerebrums through oxidative stress linked to inhibition of the Nrf2/TLR4 signaling pathway.

ENVIRONMENTAL POLLUTION (2021)

添加到收藏夹

Article Immunology

Lymphocyte Subset Alteration and Monocyte CD4 Expression Reduction in Patients with Severe COVID-19

Sumeyye Kazancioglu et al.

Summary: This study investigated alterations in peripheral blood cells in patients with COVID-19, particularly focusing on immune cell subsets. The findings revealed decreased lymphocytes, increased CD14+ 4- monocytes, and reduced expression levels of certain cells in severe COVID-19 cases. Age and CD4- monocytes were identified as independent predictors of disease severity, highlighting the importance of further research on the host immune response to SARS-CoV-2 infection for predicting disease severity and protecting against the virus.

VIRAL IMMUNOLOGY (2021)

添加到收藏夹

Article Neurosciences

Phytochemical Analysis, In Vitro Anticholinesterase, Antioxidant Activity and In Vivo Nootropic Effect of Ferula ammoniacum (Dorema ammoniacum) D. Don. in Scopolamine-Induced Memory Impairment in Mice

Nausheen Nazir et al.

Summary: This study evaluated the potential beneficial effect of Ferula ammoniacum seed extracts on learning and memory in mice. The extracts showed potent scavenging of free radicals, exhibited anticholinesterase activities, improved learning abilities, and reduced memory impairment. These findings suggest that the extracts could be utilized for managing oxidative stress, neurodegenerative diseases, and memory loss.

BRAIN SCIENCES (2021)

添加到收藏夹

Article Biology

Therapeutic effects of Typha elephantina leave's extract against paracetamol induced renal injury in rabbits

Bashir Ahmad et al.

Summary: The study demonstrates the potential of Typha elephantina leaves as a natural antioxidant to alleviate Paracetamol-induced toxicity in rabbits. The aqueous extract showed improvement in biochemical parameters and histological changes, indicating its therapeutic effects.

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2021)

添加到收藏夹

Article Biology

Phytochemical profiling and antioxidant potential of Daphne mucronata Royle and action against paracetamol-induced hepatotoxicity and nephrotoxicity in rabbits

Nausheen Nazir et al.

Summary: The methanolic extract of Daphne mucronata leaves exhibited strong antioxidant activity and protective effects against liver and kidney injuries induced by paracetamol, possibly due to its high content of phenolic and flavonoid compounds.

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2021)

添加到收藏夹

Article Pharmacology & Pharmacy